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https://www.readbyqxmd.com/read/28213958/significance-of-a-negative-sinus-p-wave-in-lead-v2-of-the-clinical-electrocardiogram
#1
Rex N MacAlpin
BACKGROUND: A negative sinus P wave in lead V2 (NPV2 ) of the electrocardiogram (ECG) is rare when leads are positioned correctly. This study was undertaken to clarify the significance of an unusually high incidence of this anomaly found in ECGs at my institution. METHODS: One thousand four hundred thirty-five ECGs were randomly selected to determine the incidence and gender frequency in tracings showing positive (PPV2 ), and biphasic (BPV2 ) P waves in V2 , as well as NPV2 ...
February 18, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28212053/transthoracic-echocardiography-pitfalls-and-limitations-as-delineated-at-cardiac-ct-and-mr-imaging
#2
Sachin B Malik, Natalie Chen, Rex A Parker, Joe Y Hsu
Transthoracic echocardiography ( TTE transthoracic echocardiography ) is a critical tool in the field of clinical cardiology. It often serves as one of the first-line imaging modalities in the evaluation of cardiac disease owing to its low cost, portability, widespread availability, lack of ionizing radiation, and ability to evaluate both anatomy and function of the heart. Consequently, a large majority of patients undergoing a cardiac computed tomography (CT) or magnetic resonance (MR) imaging examination will have a TTE transthoracic echocardiography available for review...
February 17, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28202277/sub-lethal-effects-of-a-glyphosate-based-commercial-formulation-and-adjuvants-on-juvenile-oysters-crassostrea-gigas-exposed-for-35days
#3
Alexis Séguin, Antoine Mottier, Carole Perron, Jean Marc Lebel, Antoine Serpentini, Katherine Costil
Glyphosate-based herbicides include active matter and adjuvants (e.g. polyethoxylated tallow amines, POEAs). In addition to a previous investigation on the effect of glyphosate on oysters, the aim of the present study was to investigate the effects of sub-chronic exposures (35days) to three concentrations (0.1, 1 and 100μgL(-1)) of Roundup Express® (REX) and POEAs on oysters belonging to the same age group. Low mortality rates were calculated, and only few significant differences (i.e. shell length) between exposure conditions were observed at a given date...
February 12, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28196033/thromboembolic-disease-in-patients-with-metastatic-femoral-lesions-a-comparison-between-prophylactic-fixation-and-fracture-fixation
#4
Arun Aneja, Jimmy J Jiang, Anna Cohen-Rosenblum, Hue L Luu, Terrance D Peabody, Samer Attar, T David Luo, Rex C Haydon
BACKGROUND: We are not aware of any previous studies that have compared the rate of venous thromboembolic events in patients who underwent prophylactic intramedullary nailing because of an impending fracture with the rate in patients who underwent intramedullary nailing after a pathological fracture. The objective of the present study was to determine if the rate of venous thromboembolic events varies between patients who are managed with prophylactic fixation and those who are managed with fixation after a pathological fracture...
February 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28193579/zinc-enhances-intestinal-epithelial-barrier-function-through-the-pi3k-akt-mtor-signaling-pathway-in-caco-2-cells
#5
Yuxin Shao, Patricia G Wolf, Shuangshuang Guo, Yuming Guo, H Rex Gaskins, Bingkun Zhang
Zinc plays an important role in maintaining intestinal barrier function as well as modulating cellular signaling recognition and protein kinase activities. The phosphatidylinositol 3-kinase (PI3K) cascade has been demonstrated to affect intercellular integrity and tight junction (TJ) proteins. The current study investigated the hypothesis that zinc regulates intestinal intercellular junction integrity through the PI3K/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway. A transwell model of Caco-2 cell was incubated with 0, 50 and 100 μM of zinc at various time points...
January 31, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28188133/pd1-blockade-with-pembrolizumab-is-highly-effective-in-relapsed-or-refractory-nk-t-cell-lymphoma-failing-l-asparaginase
#6
Yok-Lam Kwong, Thomas S Y Chan, Daryl Tan, Seok Jin Kim, Li-Mei Poon, Benjamin Mow, Pek-Lan Khong, Florence Loong, Rex Au-Yeung, Jabed Iqbal, Colin Phipps, Eric Tse
Natural killer (NK)/T-cell lymphomas failing L-asparaginse-regimens have no known salvage and are almost invariably fatal. Seven male NK/T-cell lymphoma patients (age: 49, 31-68, years) failing 2 (1-5) regimens (including L-asparaginase-regimens, and allogeneic hematopoietic stem cell transplantation, HSCT, in 2 cases), were treated with the anti-programmed-death-1 (PD1) antibody pembrolizumab. All patients responded, according to various clinical, radiologic (positron emission tomography), morphologic and molecular (circulating Epstein-Barr virus, EBV, DNA) criteria...
February 10, 2017: Blood
https://www.readbyqxmd.com/read/28186023/randomized-trial-of-population-based-clinical-decision-support-to-facilitate-care-transitions
#7
Eric L Eisenstein, Janese M Willis, Rex Edwards, Kevin J Anstrom, Kensaku Kawamoto, Guilherme Del Fiol, Fred S Johnson, David F Lobach
Medicaid beneficiaries in 6 North Carolina counties were randomly assigned to 1 of 3 clinical decision support (CDS) care transition strategies: (1) usual care (Control), (2) CDS messaging to patients and their medical homes (Reports), or (3) CDS messaging to patients, their medical homes, and their care managers (Reports+). We included 7146 Medicaid patients and evaluated transitions from specialist visit, ER and hospital encounters back to the patient's medical home. Patients enrolled in Medicare and Medicaid were not eligible...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28183499/an-87-year-old-woman-with-pleural-effusion-and-tortuous-aorta
#8
Bruce Sabath, Rimoun Hakim, Rex Yung
No abstract text is available yet for this article.
February 2017: Chest
https://www.readbyqxmd.com/read/28181962/use-of-narrow-band-imaging-in-the-diagnosis-of-hypovascular-endobronchial-sarcoidosis
#9
Rimoun Hakim, Bruce Sabath, Tugba Kaplan, Rex Yung
Narrow band imaging (NBI) has been widely applied for the evaluation of numerous disease conditions that present with increased vascularity of the mucosa, most often malignancies. It is increasingly being used in benign conditions as well. We present the first case in which NBI was used, rather, to detect areas of bronchial hypovascularity due to its ability to increase the visual contrast between normal and hypovascular mucosa. Endobronchial biopsy of these nodules led to the diagnosis of sarcoidosis. Had conventional white light alone been utilized, the diagnosis would likely have been missed because not only were these lesions difficult to visualize under white light but transbronchial lung biopsy and transbronchial needle aspiration were unremarkable...
February 8, 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28179950/extrusion-back-to-the-future-using-an-established-technique-to-reform-automated-chemical-synthesis
#10
REVIEW
Deborah E Crawford
Herein, the benefits which extrusion can provide for the automated continuous synthesis of organic compounds are highlighted. Extrusion is a well-established technique that has a vital role in the manufacturing processes of polymers, pharmaceuticals and food products. Furthermore, this technique has recently been applied to the solvent-free continuous synthesis of co-crystals and coordination compounds including metal-organic frameworks (MOFs). To date, a vast amount of research has already been conducted into reactive extrusion (REX), particularly in the polymer industry, which in many cases has involved organic transformations, however, it has not received significant recognition for this...
2017: Beilstein Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28165112/bayesian-network-response-regression
#11
Lu Wang, Daniele Durante, Rex E Jung, David B Dunson
No abstract text is available yet for this article.
February 6, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28158790/igfbp2-produces-rapid-acting-and-long-lasting-effects-in-rat-models-of-post-traumatic-stress-disorder-via-a-novel-mechanism-associated-with-structural-plasticity
#12
Jeffrey Burgdorf, Elizabeth M Colechio, Nayereh Ghoreishi-Haack, Amanda L Gross, Christopher S Rex, Xiao-Lei Zhang, Patric K Stanton, Roger A Kroes, Joseph R Moskal
No abstract text is available yet for this article.
February 1, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28155059/outcomes-and-financial-implications-of-intra-articular-distal-radius-fractures-a-comparative-study-of-open-reduction-internal-fixation-orif-with-volar-locking-plates-versus-nonoperative-management
#13
Dong Hao Toon, Rex Antony Xavier Premchand, Jane Sim, Rajaratnam Vaikunthan
BACKGROUND: To evaluate the functional and radiographic outcomes, as well as the treatment costs, of closed displaced intra-articular distal radius fractures treated with either open reduction internal fixation (ORIF) with volar locking plates or nonoperative treatment with plaster cast immobilisation. MATERIALS AND METHODS: A total of 60 patients (32 receiving ORIF, 28 receiving nonoperative treatment) with closed intra-articular distal radius fractures were included...
February 2, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28154928/c-rex-k-wiring-principles-and-techniques-thieme-stuttgart-new-york-delhi-rio-2016-eur-d-79-99-eur-a-82-30-chf-92-00-isbn-978-93-82076-57-5
#14
Alain G Graftiaux, Pierre Kehr
No abstract text is available yet for this article.
February 2, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28153960/race-dependent-association-of-sulfidogenic-bacteria-with-colorectal-cancer
#15
Cemal Yazici, Patricia G Wolf, Hajwa Kim, Tzu-Wen L Cross, Karin Vermillion, Timothy Carroll, Gaius J Augustus, Ece Mutlu, Lisa Tussing-Humphreys, Carol Braunschweig, Rosa M Xicola, Barbara Jung, Xavier Llor, Nathan A Ellis, H Rex Gaskins
OBJECTIVE: Colorectal cancer (CRC) incidence is higher in African Americans (AAs) compared with non-Hispanic whites (NHWs). A diet high in animal protein and fat is an environmental risk factor for CRC development. The intestinal microbiota is postulated to modulate the effects of diet in promoting or preventing CRC. Hydrogen sulfide, produced by autochthonous sulfidogenic bacteria, triggers proinflammatory pathways and hyperproliferation, and is genotoxic. We hypothesised that sulfidogenic bacterial abundance in colonic mucosa may be an environmental CRC risk factor that distinguishes AA and NHW...
February 2, 2017: Gut
https://www.readbyqxmd.com/read/28153346/usefulness-for-predicting-cardiac-events-after-orthotopic-liver-transplantation-of-myocardial-perfusion-imaging-and-dobutamine-stress-echocardiography-preoperatively
#16
David Snipelisky, Jordan Ray, Saraschandra Vallabhajosyula, Gautam Matcha, Samuel Squier, Jacob Lewis, Rex Holliday, Niti Aggarwal, J Wells Askew, Brian Shapiro, Nandan Anavekar
Patients undergoing orthotopic liver transplantation have high rates of cardiac morbidity and mortality. Although guidelines recommend noninvasive stress testing as part of the preoperative evaluation, little data have evaluated clinical outcomes following orthotopic liver transplantation. A retrospective study at 2 high-volume liver transplantation centers was performed. All patients undergoing noninvasive stress testing (myocardial perfusion imaging [MPI] or dobutamine stress echocardiography [DSE]) over a 5-year period were included...
January 6, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28131035/a-huge-diversity-of-metopids-ciliophora-armophorea-in-soil-from-the-murray-river-floodplain-australia-i-description-of-five-new-species-and-redescription-of-metopus-setosus-kahl-1927
#17
Peter Vďačný, Wilhelm Foissner
Six metopid ciliates from soil of the Murray River floodplain in Australia were studied using live observation, various silver impregnation methods, scanning electron microscopy, and multivariate statistics. One of the species is affiliated with M. setosus while the others represent new taxa. Metopus filum nov. spec. is distinguished from most congeners by the slender body, the absence of cortical granules, and the low number of ciliary rows and adoral polykinetids. Metopus palaeformides nov. spec. most resembles Heterometopus palaeformis (Kahl, 1927) Foissner, 2016b but they can be distinguished by body size, the number of adoral polykinetids, and the oral area pattern...
December 13, 2016: European Journal of Protistology
https://www.readbyqxmd.com/read/28129102/karyotypic-comparison-of-hoplias-malabaricus-bloch-1794-characiformes-erythrinidae-in-central-amazon
#18
Erika Milena Corrêa Guimarães, Natália Dayane Moura Carvalho, Carlos Henrique Schneider, Eliana Feldberg, Maria Claudia Gross
Hoplias malabaricus comprises seven karyomorphs (A-G) and evolutionary units have been described in some of them. In this study, the karyotypic composition and genomic organization of individual H. malabaricus from Central Amazon are described and to verify whether they can be classified according to known karyomorphs. Individuals from the Ducke Reserve have 2n = 42 chromosomes, similar to karyomorph A. Individuals from Catalão Lake and Marchantaria Island exhibit 2n = 40 chromosomes, similar to karyomorph C...
February 2017: Zebrafish
https://www.readbyqxmd.com/read/28127816/the-idl-of-e-coli-ssb-links-ssdna-and-protein-binding-by-mediating-protein-protein-interactions
#19
Piero R Bianco, Sasheen Pottinger, Hui Yin Tan, Trong Nguyenduc, Kervin Rex, Umesh Varshney
The E. coli single strand DNA binding protein (SSB) is essential to viability where it functions in two seemingly disparate roles: it binds to single stranded DNA (ssDNA) and to target proteins that comprise the SSB interactome. The link between these roles resides in a previously under-appreciated region of the protein known as the intrinsically disordered linker (IDL). We present a model wherein the IDL is responsible for mediating protein-protein interactions critical to each role. When interactions occur between SSB tetramers, cooperative binding to ssDNA results...
February 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28124226/erratum-to-journal-of-clinical-monitoring-and-computing-2016-end-of-year-summary-cardiovascular-and-hemodynamic-monitoring
#20
Bernd Saugel, Karim Bendjelid, Lester A Critchley, Steffen Rex, Thomas W L Scheeren
No abstract text is available yet for this article.
January 25, 2017: Journal of Clinical Monitoring and Computing
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