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https://www.readbyqxmd.com/read/28527280/-pperformance-of-led-fluorescence-microscopy-for-the-detection-of-acid-fast-bacilli-from-respiratory-samples-in-peripheral-laboratories-in-argentina
#1
María Imaz, Sonia Allassia, Mónica Aranibar, Alba Gunia, Susana Poggi, Ana Togneri, Lidia Wolff, Group Of Implementation Of Fluorescence
INTRODUCTION: Light-emitting diode fluorescence microscopy (LED-FM) has been endorsed by the World Health Organization (WHO) for tuberculosis diagnosis, but its accuracy in HIV-infected patients remains controversial, and only some few studies have explored procedural factors that may affect its performance. OBJECTIVE: To evaluate the performance of LED-FM for tuberculosis diagnosis in patients with and without HIV infection using a newer, less expensive LED lamp...
June 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28527156/the-effect-of-aerobic-or-aerobic-strength-exercise-on-body-composition-and-functional-capacity-in-patients-with-bmi-%C3%A2-35-after-bariatric-surgery-a-randomized-control-trial
#2
Alireza Hassannejad, Alireza Khalaj, Mohammad Ali Mansournia, Mastaneh Rajabian Tabesh, Zahra Alizadeh
BACKGROUND: Although previous studies suggested that bariatric surgery is the most effective and sustainable treatment method for morbid obesity in long term, but without changing in lifestyle, maintaining optimal weight loss is almost impossible. METHODS: Sixty morbid obese patients (BMI ≥ 35) were evaluated before and after 12 weeks of bariatric surgery in order to compare the impact of two different exercise programs on body composition and functional capacity outcomes...
May 19, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28526981/rubisco-mutants-of-chlamydomonas-reinhardtii-display-divergent-photosynthetic-parameters-and-lipid-allocation
#3
M G Esquível, A R Matos, J Marques Silva
Photosynthesis and lipid allocation were investigated in Rubisco small subunit mutants of the microalga Chlamydomonas reinhardtii. Comparative analyses were undertaken with cells grown photoheterotrophically under sulphur-replete or sulphur-depleted conditions. The Y67A Rubisco mutant, which has previously demonstrated a pronounced reduction in Rubisco levels and higher hydrogen production rates than the wild type, also shows the following divergences in photosynthetic phenotype and lipid allocation: (i) low Fv/Fm (maximum photochemical efficiency), (ii) low effective quantum yield of photosystem II (ΦPSII), (iii) low effectiveness at protection against high light intensities, (iv) a higher level of total lipids per pigment and (v) changes in the relative proportions of different fatty acids, with a marked decrease in unsaturated fatty acids (FAs)...
May 19, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28526431/measurement-of-apt-using-a-combined-cert-arex-approach-with-varying-duty-cycles
#4
Zhongliang Zu, Hua Li, Junzhong Xu, Xiao-Yong Zhang, Moritz Zaiss, Ke Li, Mark D Does, John C Gore, Daniel F Gochberg
The goal is to develop an imaging method where contrast reflects amide-water magnetization exchange, with minimal signal contributions from other sources. Conventional chemical exchange saturation transfer (CEST) imaging of amides (often called amide proton transfer, or APT, and quantified by the metric MTRasym) is confounded by several factors unrelated to amides, such as aliphatic protons, water relaxation, and macromolecular magnetization transfer. In this work, we examined the effects of combining our previous chemical exchange rotation (CERT) approach with the non-linear AREX method while using different duty cycles (DC) for the label and reference scans...
May 16, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28526116/allelopathic-interactions-between-the-macroalga-hizikia-fusiformis-harvey-and-the-harmful-blooms-forming-dinoflagellate-karenia-mikimotoi
#5
Zengling Ma, Mingjiang Wu, Lidong Lin, Ronald W Thring, Hengguo Yu, Xu Zhang, Min Zhao
The effects of algal blooms on seaweeds have been rarely studied, although harmful algal blooms (HABs) are now normally regarded as worldwide incidents. In the present study, the effects of dense Karenia mikimotoi cells on the growth and photosynthesis of Hizikia fusiformis, a common and commercially cultivated macroalga in coastal waters of the East China Sea (ECS), were studied to understand the possible consequences when the mariculture encountered a dense harmful algal bloom. Furthermore, the counteraction of the latter on the growth and photosynthetic activities of K...
May 2017: Harmful Algae
https://www.readbyqxmd.com/read/28525632/effect-of-baseline-characteristics-on-the-pain-response-to-pregabalin-in-fibromyalgia-patients-with-comorbid-depression
#6
Stuart L Silverman, Miroslav Backonja, Lynne Pauer, Jaren Landen, Pritha Bhadra Brown, Joseph M Scavone, Richard Vissing, Andrew Clair
Objective. : To evaluate the effect of baseline characteristics on the treatment response to pregabalin in fibromyalgia (FM) patients with depression. Design. : Post hoc analysis from a randomized, double-blind, placebo-controlled, two-way crossover study of pregabalin (300 or 450 mg/day, twice daily). Subjects. : A total of 193 FM patients taking an antidepressant for comorbid depression. Methods. : The effect of patient baseline characteristics on the treatment response to pregabalin vs placebo was assessed for the primary efficacy end point (mean pain score on an 11-point numeric rating scale)...
May 19, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28525594/availability-and-use-of-cheap-tobacco-in-the-uk-2002-2014-findings-from-the-international-tobacco-control-project
#7
Timea R Partos, Anna B Gilmore, Sara C Hitchman, Rosemary Hiscock, J Robert Branston, Ann McNeill
Introduction: Raising tobacco prices is the most effective population-level intervention for reducing smoking, but this is undermined by the availability of cheap tobacco. This study monitors trends in cheap tobacco use among adult smokers in the UK between 2002-2014 via changes in product type, purchase source, and prices paid. Methods: Weighted data from 10 waves of the International Tobacco Control policy evaluation study were used. This is a longitudinal cohort study of adult smokers with replenishment; 6169 participants provided 15812 responses...
May 19, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28524158/sequencing-of-dicer1-in-sarcomas-identifies-biallelic-somatic-dicer1-mutations-in-an-adult-onset-embryonal-rhabdomyosarcoma
#8
Leanne de Kock, Barbara Rivera, Timothée Revil, Paul Thorner, Catherine Goudie, Dorothée Bouron-Dal Soglio, Catherine S Choong, John R Priest, Paul J van Diest, Jantima Tanboon, Anja Wagner, Jiannis Ragoussis, Peter Fm Choong, William D Foulkes
BACKGROUND: Sarcomas are rare and heterogeneous cancers. We assessed the contribution of DICER1 mutations to sarcoma development. METHODS: The coding region of DICER1 was sequenced in 67 sarcomas using a custom Fluidigm Access Array. The RNase III domains were Sanger sequenced in six additional sarcomas to identify hotspot DICER1 variants. RESULTS: The median age of sarcoma diagnosis was 45.7 years (range: 3 months to 87.4 years). A recurrent embryonal rhabdomyosarcoma (ERMS) of the broad ligament, first diagnosed at age 23 years, harboured biallelic pathogenic somatic DICER1 variants (1 truncating and 1 RNase IIIb missense)...
May 18, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28524090/wind-turbine-diagnosis-under-variable-speed-conditions-using-a-single-sensor-based-on-the-synchrosqueezing-transform-method
#9
Yanjie Guo, Xuefeng Chen, Shibin Wang, Ruobin Sun, Zhibin Zhao
The gearbox is one of the key components in wind turbines. Gearbox fault signals are usually nonstationary and highly contaminated with noise. The presence of amplitude-modulated and frequency-modulated (AM-FM) characteristics compound the difficulty of precise fault diagnosis of wind turbines, therefore, it is crucial to develop an effective fault diagnosis method for such equipment. This paper presents an improved diagnosis method for wind turbines via the combination of synchrosqueezing transform and local mean decomposition...
May 18, 2017: Sensors
https://www.readbyqxmd.com/read/28524026/-high-flow-nasal-cannulae-oxygen-in-patients-with-respiratory-failure-a-meta-analysis
#10
Weigang Yue, Zhigang Zhang, Caiyun Zhang, Liping Yang, Jufang He, Yuying Hou, Ying Tang, Jinhui Tian
OBJECTIVE: To systematically evaluate the efficacy of high-flow nasal cannulae oxygen (HFNC) in patients with respiratory failure. METHODS: Computerized PubMed, Embase, Web of Science, the Cochrane Library, CNKI, CBM, VIP, Wanfang Database up to March 31st, 2017, all published available randomized controlled trials (RCTs) or cohort studies about HFNC therapy for patients with respiratory failure were searched. The control group was treated with face mask oxygen therapy (FM) or non-invasive positive pressure ventilation (NIPPV), while the experimental group was treated with HFNC...
May 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28521738/multidimensional-daily-diary-of-fatigue-fibromyalgia-17-items-mdf-fibro-17-part-2-psychometric-evaluation-in-fibromyalgia-patients
#11
Y Li, S Morris, J Cole, S Dube', J A M Smith, C Burbridge, T Symonds, S Hudgens, W Wang
BACKGROUND: The Multidimensional Daily Diary of Fatigue-Fibromyalgia-17 instrument (MDF-Fibro-17) has been developed for use in fibromyalgia (FM) clinical studies and includes 5 domains: Global Fatigue Experience, Cognitive Fatigue, Physical Fatigue, Motivation, and Impact on Function. Psychometric properties of the MDF-Fibro-17 needed to demonstrate the appropriateness of using this instrument in clinical studies are presented. METHODS: Psychometric analyses were conducted to evaluate the factor structure, reliability, validity, and responsiveness of the MDF-Fibro-17 using data from a Phase 2 clinical study of FM patients (N = 381)...
May 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28516759/reduced-graphene-oxide-wrapped-nickel-rich-cathode-materials-for-lithium-ion-batteries
#12
Jae-Hyun Shim, Young-Min Kim, Miji Park, Jongsik Kim, Sanghun Lee
The encapsulation of Ni-rich cathode materials (LiNi0.6Co0.2Mn0.2O2) for lithium ion batteries in reduced graphene oxide (rGO) sheets is introduced to improve electrochemical performances. Using (3-aminopropyl)triethoxysilane, the active materials are completely wrapped with several rGO layers of ~2 nm thickness. By virtue of the great electrical conductivity of graphene, the rGO-coated cathode materials exhibit much enhanced electrochemical performances of cycling property and rate capability. In addition, it is shown that the structural degradation of the active materials, which is from the rhombohedral layered structure (R-3 m) to the spinel (Fd-3 m) or rock-salt phase (Fm-3 m), is significantly reduced as well as delayed due to the protection of the active materials in the rGO layers from direct contact with electrolytes and the consequent suppression of side reactions...
May 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28515718/fungal-diversity-in-field-mold-damaged-soybean-fruits-and-pathogenicity-identification-based-on-high-throughput-rdna-sequencing
#13
Jiang Liu, Jun-Cai Deng, Cai-Qiong Yang, Ni Huang, Xiao-Li Chang, Jing Zhang, Feng Yang, Wei-Guo Liu, Xiao-Chun Wang, Tai-Wen Yong, Jun-Bo Du, Kai Shu, Wen-Yu Yang
Continuous rain and an abnormally wet climate during harvest can easily lead to soybean plants being damaged by field mold (FM), which can reduce seed yield and quality. However, to date, the underlying pathogen and its resistance mechanism have remained unclear. The objective of the present study was to investigate the fungal diversity of various soybean varieties and to identify and confirm the FM pathogenic fungi. A total of 62,382 fungal ITS1 sequences clustered into 164 operational taxonomic units (OTUs) with 97% sequence similarity; 69 taxa were recovered from the samples by internal transcribed spacer (ITS) region sequencing...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28515064/genetics-of-serum-carotenoid-concentrations-and-their-correlation-with-obesity-related-traits-in-mexican-american-children
#14
Vidya S Farook, Lavanya Reddivari, Srinivas Mummidi, Sobha Puppala, Rector Arya, Juan Carlos Lopez-Alvarenga, Sharon P Fowler, Geetha Chittoor, Roy G Resendez, Birunda Mohan Kumar, Anthony G Comuzzie, Joanne E Curran, Donna M Lehman, Christopher P Jenkinson, Jane L Lynch, Ralph A DeFronzo, John Blangero, Daniel E Hale, Ravindranath Duggirala, Jairam Kp Vanamala
Background: Dietary intake of phytonutrients present in fruits and vegetables, such as carotenoids, is associated with a lower risk of obesity and related traits, but the impact of genetic variation on these associations is poorly understood, especially in children.Objective: We estimated common genetic influences on serum carotenoid concentrations and obesity-related traits in Mexican American (MA) children.Design: Obesity-related data were obtained from 670 nondiabetic MA children, aged 6-17 y. Serum α- and β-carotenoid concentrations were measured in ∼570 (α-carotene in 565 and β-carotene in 572) of these children with the use of an ultraperformance liquid chromatography-photodiode array...
May 17, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28514233/energy-balance-over-one-athletic-season
#15
Analiza M Silva, Catarina N Matias, Diana A Santos, Diana Thomas, Anja Bosy-Westphal, Manfred J Müller, Steven B Heymsfield, Luís B Sardinha
INTRODUCTION: Magnitude and variation in energy balance (EB) components over an athletic season are largely unknown. PURPOSE: We investigated the longitudinal changes in EB over one season and explored the association between EB variation and the change in the main fat-free mass (FFM) components in highly trained athletes. METHODS: Eighty athletes (54 males; handball, volleyball, basketball, triathlete, and swimming) were evaluated from the beginning of the season to the main competition stage...
March 22, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28511678/multidimensional-daily-diary-of-fatigue-fibromyalgia-17-items-mdf-fibro-17-part-1-development-and-content-validity
#16
S Morris, Y Li, J A M Smith, S Dube', C Burbridge, T Symonds
BACKGROUND: Fibromyalgia (FM), a disorder characterized by chronic widespread pain and tenderness, affects greater than five million individuals in the United States alone. Patients experience multiple symptoms in addition to pain, and among them, fatigue is one of the most bothersome and disabling. There is a growing body of literature suggesting that fatigue is a multidimensional concept. Currently, to our knowledge, no multidimensional Patient Reported Outcome (PRO) measure of FM-related fatigue meets Food and Drug Administration (FDA) requirements to support a product label claim...
May 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28511284/non-mix-fragrances-are-top-sensitizers-in-consecutive-dermatitis-patients%C3%A2-%C3%A2-a-cross-sectional-study-of-the-26-eu-labelled-fragrance-allergens
#17
Niels H Bennike, Claus Zachariae, Jeanne D Johansen
BACKGROUND: For cosmetics, it is mandatory to label 26 fragrance substances, including all constituents of fragrance mix I (FM I) and fragrance mix II (FM II). Earlier reports have not included oxidized R-limonene [hydroperoxides of R-limonene (Lim-OOH)] and oxidized linalool [hydroperoxides of linalool (Lin-OOH)], and breakdown testing of FM I and FM II has mainly been performed in selected, mix-positive patients. OBJECTIVES: To report the prevalence of sensitization to the 26 fragrances, and to assess concomitant reactivity to FM I and/or FM II...
May 16, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28510766/detection-of-3-3-dichlorobiphenyl-in-human-maternal-plasma-and-its-effects-on-axonal-and-dendritic-growth-in-primary-rat-neurons
#18
Sunjay Sethi, Kimberly P Keil, Hao Chen, Keri Hayakawa, Xueshu Li, Yanping Lin, Hans-Joachim Lehmler, Birgit Puschner, Pamela J Lein
3,3'-Dichlorobiphenyl (PCB 11), a byproduct of pigment production, is increasingly detected in environmental samples. While more highly chlorinated PCB congeners are known developmental neurotoxicants, nothing is known about the potential developmental neurotoxicity of PCB 11. To address this critical data gap, we measured PCB 11 levels in human maternal plasma and quantified the effects of PCB 11 and its major metabolites on morphometric parameters of neuronal connectivity in cultured primary neurons. Mass spectrometry analyses of plasma from 241 pregnant women enrolled in the MARBLES study (University of California, Davis) detected PCB 11 in all samples at concentrations ranging from 0...
May 16, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28506845/ex-vivo-mesenchymal-precursor-cell-expanded-cord-blood-transplantation-following-reduced-intensity-conditioning-regimens-improves-time-to-neutrophil-recovery
#19
Rohtesh S Mehta, Rima M Saliba, Kai Cao, Indreshpal Kaur, Katy Rezvani, Julianne Chen, Amanda Olson, Simrit Parmar, Nina Shah, David Marin, Amin Alousi, Chitra Hosing, Uday Popat, Partow Kebriaei, Richard Champlin, Marcos de Lima, Donna Skerrett, Elizabeth Burke, Elizabeth J Shpall, Betul Oran
We previously showed the safety of using cord blood (CB) expanded ex vivo in cocultures with allogeneic mesenchymal precursor cells (MPC) after myeloablative conditioning with faster recovery of neutrophils and platelets compared with historical controls. Herein, we report the transplant outcomes of 27 patients with hematologic cancers who received one CB unit ex vivo expanded with MPCs in addition to an unmanipulated CB (MPC group) after reduced intensity conditioning (RIC). The results in this group were compared with 51 historical controls who received two unmanipulated CB units (control group)...
May 12, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28506257/an-overview-of-systematic-reviews-of-complementary-and-alternative-therapies-for-fibromyalgia-using-both-amstar-and-robis-as-quality-assessment-tools
#20
Rachel Perry, Verity Leach, Philippa Davies, Chris Penfold, Andy Ness, Rachel Churchill
BACKGROUND: Fibromyalgia (FM) is a chronic, debilitating pain disorder. Dissatisfaction with conventional medicine can lead people with FM to turn to complementary and alternative medicine (CAM). Two previous overviews of systematic reviews of CAM for FM have been published, but they did not assessed for risk of bias in the review process. METHODS: Five databases Medline, Embase, AMED (via OVID), Web of Science and Central were searched from their inception to December 2015...
May 15, 2017: Systematic Reviews
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