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https://www.readbyqxmd.com/read/28448425/vulnerability-to-psychopathology-and-dimensions-of-personality-in-patients-with-fibromyalgia
#1
Alba Garcia-Fontanals, Mariona Portell, Susanna García-Blanco, Violant Poca-Dias, Ferran García-Fructuoso, Marina López-Ruiz, Teresa Gutiérrez-Rosado, Montserrat Gomà-I-Freixanet, Joan Deus
OBJECTIVE: Fibromyalgia (FM) patients may present psychopathology and some characteristic personality traits that may affect their adaptation to the disease. This paper aims to study the relationship between personality dimensions according to the psychobiological model of Cloninger and the presence of psychopathology. METHOD: The study sample consisted of 42 patients with FM and 38 healthy controls. The assessment instruments administered were the Temperament and Character Inventory (TCI-R) and the Millon Clinical Multiaxial Inventory (MCMI-III)...
April 26, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28448210/body-composition-and-inflammatory-markers-in-pubertal-girls-comparison-between-athletes-and-non-athletic-controls
#2
Jaak Jürimäe, Kristel Võsoberg, Anna-Liisa Tamm, Katre Maasalu, Liina Remmel, Vallo Tillmann
Various inflammation parameters are increased with childhood obesity, but few comparable data are found in lean growing athletes. This study aims to characterize differences in 12 simultaneously measured inflammatory parameters between pubertal rhythmic gymnasts (RG) and untrained controls (UC), and to examine the relationship between body composition and inflammatory markers. Sixty 10-12-year-old girls were divided into RG (n = 30) and UC (n = 30). Fat mass (FM) and fat free mass (FFM) were measured by dual-energy X-ray absorptiometry...
April 27, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28446247/difference-in-oxidative-stress-tolerance-between-rice-cultivars-estimated-with-chlorophyll-fluorescence-analysis
#3
Ichiro Kasajima
BACKGROUND: Oxidative stress is considered to be involved in growth retardation of plants when they are exposed to a variety of biotic and abiotic stresses. Despite its potential importance in improving crop production, comparative studies on oxidative stress tolerance between rice (Oryza sativa L.) cultivars are limited. This work describes the difference in term of oxidative stress tolerance between 72 rice cultivars. METHODS: 72 rice cultivars grown under naturally lit greenhouse were used in this study...
April 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28446030/anthropometric-measures-are-not-accurate-predictors-of-fat-mass-in-als
#4
Zara A Ioannides, Frederik J Steyn, Robert D Henderson, Pamela A Mccombe, Shyuan T Ngo
BACKGROUND: Anthropometric measurements including body mass index (BMI) and body adiposity index (BAI) are widely employed as indicators of fat mass (FM). Metabolic abnormalities in amyotrophic lateral sclerosis (ALS) impact disease progression, therefore assessment of FM informs care. The aim of this study was to determine whether BMI and BAI are accurate predictors of FM in ALS. Methodology and main findings: BMI, BAI and percentage FM (determined by air displacement plethysmography; FM-ADP) were measured in control (n = 35) and ALS (n = 44) participants...
April 27, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28445454/body-composition-at-birth-and-its-relationship-with-neonatal-anthropometric-ratios-the-newborn-body-composition-study-of-the-intergrowth-21st-project
#5
José Villar, Fabien A Puglia, Tanis R Fenton, L Cheikh Ismail, Eleonora Staines-Urias, Francesca Giuliani, Eric O Ohuma, Cesar G Victora, Peter Sullivan, Fernando C Barros, Ann Lambert, Aris T Papageorghiou, Roseline Ochieng, Yasmin A Jaffer, Douglas G Altman, Alison J Noble, Michael G Gravett, Manorama Purwar, Ruyan Pang, Ricardo Uauy, Stephen H Kennedy, Zulfiqar A Bhutta
BACKGROUND: We aimed to describe newborn body composition and identify which anthropometric ratio (weight/length; BMI; or ponderal index, PI) best predicts fat mass (FM) and fat-free mass (FFM). METHODS: Air-displacement plethysmography (PEA POD) was used to estimate FM, FFM and body fat percentage (BF%). Associations between FFM, FM and BF% and weight/length, BMI and PI were evaluated in 1,019 newborns using multivariate regression analysis. Charts for FM, FFM and BF% were generated using a prescriptive sub-sample (n=247)...
April 26, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28444988/inhibitory-action-of-oxytocin-on-spontaneous-contraction-of-rat-distal-colon-by-nitrergic-mechanism-involvement-of-cyclic-gmp-and-apamin-sensitive-k-channels
#6
R Wang, M T Han, X L Lv, Y A Yu, S Q Chai, C M Qu, C Y Liu
AIM: The mechanisms underlying the inhibitory effects of oxytocin (OT) on colon tone are not totally understood. We explore the mechanisms of OT on spontaneous contractility in rat distal colon, and identify the mediators involved in this action. METHODS: In rat distal colon strips, mechanical activity was analyzed and the production of nitric oxide (NO) in tissue loaded with the fluorochrome DAF-FM was visualized by confocal microscopy. OT receptor (OTR) expression was determined by western blotting and immunofluorescence...
April 26, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28443830/paco-sub-2-sub-measurement-in-cerebral-haemodynamics-face-mask-or-nasal-cannulae
#7
Jatinder Singh Minhas, Thompson Robinson, Ronney Panerai
Objective PaCO2 affects cerebral blood flow (CBF) and its regulatory mechanisms, but the effects of CO2 measurement technique on cerebrovascular parameters are unknown. In order to determine if the two most commonly used approaches, face mask (FM) or nasal cannulae (NC), are interchangeable or not, we tested the hypothesis that the use of FM versus NC does not lead to significant differences in CO2-related systemic and cerebrovascular parameters. Approach Recordings of CBF velocity (CBFV), blood pressure (BP), heart rate, and end-tidal CO2 (EtCO2) were performed in 42 subjects during normocapnia (FM or NC) and 5% CO2 inhalation (FM) or hyperventilation (NC)...
April 26, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28442780/the-effect-of-body-composition-and-serum-inflammatory-markers-on-the-functional-muscle-bone-unit-in-premenopausal-women
#8
S M Mueller, I Herter-Aeberli, A C Cepeda-Lopez, M Flück, H H Jung, M Toigo
BACKGROUND/OBJECTIVES: A number of recent studies dealing with the relationship between the effects of high body mass (BM) and fat mass (FM) on bone mass and strength exhibit a range of contrasting variations in their findings. These diverse findings have led to an ongoing controversy as to whether high BM and FM positively or negatively affect bone mass and strength. Excessive fat mass and the associated low-grade inflammation might overturn the higher mechanical stimulus arising from a higher body mass...
April 26, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28441766/fat-mass-is-positively-associated-with-estimated-hip-bone-strength-among-chinese-men-aged-50-years-and-above-with-low-levels-of-lean-mass
#9
Guiyuan Han, Yu-Ming Chen, Hua Huang, Zhanyong Chen, Lipeng Jing, Su-Mei Xiao
This study investigated the relationships of fat mass (FM) and lean mass (LM) with estimated hip bone strength in Chinese men aged 50-80 years (median value: 62.0 years). A cross-sectional study including 889 men was conducted in Guangzhou, China. Body composition and hip bone parameters were generated by dual-energy X-ray absorptiometry (DXA). The relationships of the LM index (LMI) and the FM index (FMI) with bone phenotypes were detected by generalised additive models and multiple linear regression. The associations between the FMI and the bone variables in LMI tertiles were further analysed...
April 24, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28440280/targeting-asic3-for-relieving-mice-fibromyalgia-pain-roles-of-electroacupuncture-opioid-and-adenosine
#10
Liang-Ta Yen, Ching-Liang Hsieh, Hsin-Cheng Hsu, Yi-Wen Lin
Many scientists are seeking better therapies for treating fibromyalgia (FM) pain. We used a mouse model of FM to determine if ASIC3 and its relevant signaling pathway participated in FM pain. We demonstrated that FM-induced mechanical hyperalgesia was attenuated by electroacupuncture (EA). The decrease in fatigue-induced lower motor function in FM mice was also reversed by EA. These EA-based effects were abolished by the opioid receptor antagonist naloxone and the adenosine A1 receptor antagonist rolofylline...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28439841/label-free-direct-detection-of-mirnas-with-poly-silicon-nanowire-biosensors
#11
Jing He, Jianjun Zhu, Bin Jiang, Yulan Zhao
The diagnostic and prognostic value of microRNAs (miRNAs) in diseases becomes promising. Owing to fast response and high sensitivity, silicon nanowire (SiNW) biosensor has been considered a potential tool for miRNAs detection. Here, we describe a booming method to detect miRNAs with poly-silicon nanowire biosensors. Standard and real miRNA samples are applied in this study. The results show a limitation of 1 fM in the detection of standard miRNA sample with our poly-nanowire devices. Meanwhile, one-base mismatched sequence could be distinguished...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28439838/mirna-quantitation-with-microelectrode-sensors-enabled-by-enzymeless-electrochemical-signal-amplification
#12
Tanyu Wang, Gangli Wang, Didier Merlin, Emilie Viennois
Quantification of circulating microRNAs (miRNAs) is of great interest because of their potentials as disease biomarkers. Currently, quantitative reverse transcription polymerase chain reaction (qRT-PCR) and microarray are considered mainstream techniques for miRNA identification and quantitation. However, these techniques are challenged by the low levels and wide dynamic range (from aM to nM) of miRNAs in a physiological sample, as well as the difficulty in the implementation in point-of-care settings. Here, we describe a one-step label-free electrochemical sensing technique by assembling a triple-stem DNA-redox probe structure on a gold microelectrode and introducing a reductant, tris(2-carboxyethyl) phosphine hydrochloride (TCEP) in the detection buffer solution to achieve ultrasensitive miRNAs detection with a detection limit of 0...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28438566/t-type-voltage-gated-calcium-channels-are-involved-in-endothelium-dependent-relaxation-of-mice-pulmonary-artery
#13
Guillaume Gilbert, Arnaud Courtois, Mathilde Dubois, Laure-Anne Cussac, Thomas Ducret, Philippe Lory, Roger Marthan, Jean-Pierre Savineau, Jean-François Quignard
In pulmonary arterial endothelial cells, Ca(2+) channels and intracellular Ca(2+)concentration ([Ca(2+)]i) control the release of vasorelaxant factors such as nitric oxide and are involved in the regulation of pulmonary arterial blood pressure. The present study was undertaken to investigate the implication of T-type voltage-gated Ca(2+)channels (T-VGCCs, Cav3.1 channel) in the endothelium-dependent relaxation of intrapulmonary arteries. Relaxation was quantified by means of a myograph in wild type and Cav3...
April 21, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28437637/analysis-of-free-moment-and-center-of-pressure-frequency-components-during-quiet-standing-using-magnitude-squared-coherence
#14
Dean C Hay, Mark P Wachowiak
To date, no postural studies have investigated the specific relationship between linear (anteroposterior (AP) and mediolateral (ML)) postural sway and the free moment (FM) over the range of biomechanically important frequencies. The goal of the current paper is to study the relationship between FM and the AP/ML movements during quiet standing with respect to individual frequencies. Mean squared coherence, which measures the degree of the relationship between two signals as a function of frequency, is employed to address this question...
April 21, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28437220/lean-mass-and-fat-mass-as-mediators-of-the-relationship-between-physical-activity-and-bone-mineral-density-in-postmenopausal-women
#15
Jing Xiang, Yongjie Chen, Yupeng Wang, Shaofei Su, Xinyu Wang, Biao Xie, Qiuju Zhang, Meina Liu
BACKGROUND: The relationship between physical activity (PA) and bone health is well known, but the role of lean mass (LM) and fat mass (FM) in this relationship remains uncertain. Therefore, the aim of this study was to examine the mediating effect of LM and FM on the relationship between PA and bone mineral density (BMD) in postmenopausal women. MATERIALS AND METHODS: This cross-sectional study involved 282 postmenopausal women aged between 50 and 65 year, who were randomly selected from Hongqi community of Harbin City in China...
February 28, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28434989/colorimetric-detection-of-microrna-based-hybridization-chain-reaction-for-signal-amplification-and-enzyme-for-visualization
#16
Na Ying, Taifan Sun, Zhibao Chen, Guangping Song, Bingyao Qi, Shengjun Bu, Xiuwei Sun, Jiayu Wan, Zehong Li
MicroRNAs (miRNAs) have key roles in gene expression and can be employed as biomarkers for early diagnosis of various diseases, especially cancers. Detection of miRNAs remains challenging and often requires detection platforms. Here, a horseradish peroxidase (HRP)-assisted hybridization chain reaction (HCR) for colorimetric detection of miR-155 was described. In the presence of target miRNA, the capture probe immobilized on the microplate sandwiched the target miR-155 with the 3' end of the reporter probe. Another exposed part of the RP at the 5'end triggered HCR producing double-stranded DNA polymers with multiple fluorescein isothiocyanates (FITC) for signal amplification...
April 20, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28434208/dietary-interventions-for-adults-with-chronic-kidney-disease
#17
REVIEW
Suetonia C Palmer, Jasjot K Maggo, Katrina L Campbell, Jonathan C Craig, David W Johnson, Bernadet Sutanto, Marinella Ruospo, Allison Tong, Giovanni Fm Strippoli
BACKGROUND: Dietary changes are routinely recommended in people with chronic kidney disease (CKD) on the basis of randomised evidence in the general population and non-randomised studies in CKD that suggest certain healthy eating patterns may prevent cardiovascular events and lower mortality. People who have kidney disease have prioritised dietary modifications as an important treatment uncertainty. OBJECTIVES: This review evaluated the benefits and harms of dietary interventions among adults with CKD including people with end-stage kidney disease (ESKD) treated with dialysis or kidney transplantation...
April 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28432885/from-laboratory-to-field-studies-the-assessment-of-biscutella-laevigata-suitability-to-biological-reclamation-of-areas-contaminated-with-lead-and-cadmium
#18
Ewa Muszyńska, Ewa Hanus-Fajerska, Barbara Piwowarczyk, Joanna Augustynowicz, Krystyna Ciarkowska, Tomasz Czech
The aim of the work was to evaluate the usefulness of the in vitro multiplication of Biscutella laevigata calamine ecotype for in situ reclamation of post-flotation wastes polluted with Pb and Cd. The experiment was conducted on three steps: (i) plant shoots' production under in vitro condition, (ii) establishment of the material in greenhouse experiment, and finally (iii) field cultivation directly on the mining-waste heap of Olkusz Ore-Bearing Region, Poland. This region is known to be one of the most chemically-degraded area in central Europe...
April 19, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28431972/mitochondrial-energy-metabolism-of-rat-hippocampus-after-treatment-with-the-antidepressants-desipramine-and-fluoxetine
#19
Roberto Federico Villa, Federica Ferrari, Laura Bagini, Antonella Gorini, Nicoletta Brunello, Fabio Tascedda
Alterations in mitochondrial functions have been hypothesized to participate in the pathogenesis of depression, because brain bioenergetic abnormalities have been detected in depressed patients by neuroimaging in vivo studies. However, this hypothesis is not clearly demonstrated in experimental studies: some suggest that antidepressants are inhibitors of mitochondrial metabolism, while others observe the opposite. In this study, the effects of 21-day treatment with desipramine (15 mg/kg) and fluoxetine (10 mg/kg) were examined on the energy metabolism of rat hippocampus, evaluating the catalytic activity of regulatory enzymes of mitochondrial energy-yielding metabolic pathways...
April 18, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28429595/ultrasensitive-detection-of-micrornas-with-morpholino-functionalized-nanochannel-biosensor
#20
Tangbin Liao, Xiaorui Li, Qian Tong, Kai Zou, Hang Zhang, Lina Tang, Zhongyue Sun, Guo-Jun Zhang
Here we demonstrate a phosphorodiamidate morpholino oligos (PMO)-functionlized nanochannel biosensor for label-free detection of microRNAs (miRNAs) with ultrasensitivity and high sequence-specificity. PMO, as a capture probe, was covalently anchored on the nanochannel surface. Because of the neutral character and high sequence-specific affinity of PMO, hybridization efficiency between PMO and miRNAs was enhanced, thus decreasing background signals largely and improving the detection specificity and sensitivity highly...
April 21, 2017: Analytical Chemistry
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