Huating Li, Lei Zhang, Jun Li, Qian Wu, Lingling Qian, Junsheng He, Yueqiong Ni, Petia Kovatcheva-Datchary, Rui Yuan, Shuangbo Liu, Li Shen, Mingliang Zhang, Bin Sheng, Ping Li, Kang Kang, Liang Wu, Qichen Fang, Xiaoxue Long, Xiaolin Wang, Yanli Li, Yaorui Ye, Jianping Ye, Yuqian Bao, Yueliang Zhao, Guowang Xu, Xinyu Liu, Gianni Panagiotou, Aimin Xu, Weiping Jia
Emerging evidence suggests that modulation of gut microbiota by dietary fibre may offer solutions for metabolic disorders. In a randomized placebo-controlled crossover design trial (ChiCTR-TTRCC-13003333) in 37 participants with overweight or obesity, we test whether resistant starch (RS) as a dietary supplement influences obesity-related outcomes. Here, we show that RS supplementation for 8 weeks can help to achieve weight loss (mean -2.8 kg) and improve insulin resistance in individuals with excess body weight...
February 26, 2024: Nature metabolism