keyword
MENU ▼
Read by QxMD icon Read
search

PPCPs

keyword
https://www.readbyqxmd.com/read/28412404/development-of-human-biotransformation-qsars-and-application-for-pbt-assessment-refinement
#1
Ester Papa, Alessandro Sangion, Jon A Arnot, Paola Gramatica
Toxicokinetics heavily influence chemical toxicity as the result of Absorption, Distribution, Metabolism (Biotransformation) and Elimination (ADME) processes. Biotransformation (metabolism) reactions can lead to detoxification or, in some cases, bioactivation of parent compounds to more toxic chemicals. Moreover, biotransformation has been recognized as a key process determining chemical half-life in an organism and is thus a key determinant for bioaccumulation assessment for many chemicals. This study addresses the development of QSAR models for the prediction of in vivo whole body human biotransformation (metabolism) half-lives measured or empirically-derived for over 1000 chemicals, mainly represented by pharmaceuticals...
April 13, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28384602/removal-characteristics-of-pharmaceuticals-and-personal-care-products-comparison-between-membrane-bioreactor-and-various-biological-treatment-processes
#2
Junwon Park, Naoyuki Yamashita, Chulhwi Park, Tatsumi Shimono, Daniel M Takeuchi, Hiroaki Tanaka
We investigated the concentrations of 57 target compounds in the different treatment units of various biological treatment processes in South Korea, including modified biological nutrient removal (BNR), anaerobic-anoxic-aerobic (A2O), and membrane bioreactor (MBR) systems, to elucidate the occurrence and removal fates of PPCPs in WWTPs. Biological treatment processes appeared to be most effective in eliminating most PPCPs, whereas some PPCPs were additionally removed by post-treatment. With the exception of the MBR process, the A2O system was effective for PPCPs removal...
April 2, 2017: Chemosphere
https://www.readbyqxmd.com/read/28364207/effects-of-applying-biosolids-to-soils-on-the-adsorption-and-bioavailability-of-17%C3%AE-ethinylestradiol-and-triclosan-in-wheat-plants
#3
Romina Cantarero, Pablo Richter, Sally Brown, Loreto Ascar, Inés Ahumada
Biosolids contain inorganic and organic contaminants, including pharmaceutical and personal care products (PPCPs) that have accounted for a series of emerging contaminants, such as triclosan (TCS) and the hormone 17α-ethinylestradiol (EE2). The general aim of this study was to evaluate the effects of biosolid application on EE2 and TCS adsorption and bioavailability in soils through testing with wheat plants. For the bioavailability study, sand and two soils, Lampa and Lo Prado, were used. The sand and soils were treated using two biosolid application rates (0 and 90 mg ha(-1)), and the EE2 and TCS concentrations in the biosolids were determined as 0...
April 1, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28360000/spatial-distribution-of-organic-contaminants-in-three-rivers-of-southern-england-bound-to-suspended-particulate-material-and-dissolved-in-water
#4
John L Wilkinson, Peter S Hooda, Julian Swinden, James Barker, Stephen Barton
The spatial distribution of pharmaceuticals, personal care products (PPCPs) and other emerging contaminants (ECs) such as plasticisers, perflourinated compounds (PFCs) and illicit drug metabolites in water and bound to suspended particulate material (SPM) is not well-understood. Here, we quantify levels of thirteen selected contaminants in water (n=88) and their partition to suspended particulate material (SPM, n=16) in three previously-unstudied rivers of Greater London and Southern England during a key reproduction/spawning period...
March 27, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28346910/occurrence-temporal-variation-and-estrogenic-burden-of-five-parabens-in-sewage-sludge-collected-across-the-united-states
#5
Jing Chen, Benny F G Pycke, Bruce J Brownawell, Chad A Kinney, Edward T Furlong, Dana W Kolpin, Rolf U Halden
Five parabens used as preservatives in pharmaceuticals and personal care products (PPCPs) were measured in sewage sludges collected at 14 U.S. wastewater treatment plants (WWTPs) located in nine states. Detected concentration ranges (ng/g, dry weight) and frequencies were as follows: methyl paraben (15.9 to 203.0; 100%), propyl paraben (0.5 to 7.7; 100%), ethyl paraben (<0.6 to 2.6; 63%), butyl paraben (<0.4 to 4.3; 42%) and benzyl paraben (<0.4 to 3.3; 26%). The estrogenicity inherent to the sum of parabens detected in sewage sludge (ranging from 10...
March 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28342346/can-wastewater-based-epidemiology-be-used-to-evaluate-the-health-impact-of-temperature-an-exploratory-study-in-an-australian-population
#6
Dung Phung, Jochen Mueller, Foon Yin Lai, Jake O'Brien, Nhung Dang, Lidia Morawska, Phong K Thai
Ambient temperature is known to have impact on population health but assessing its impact by the traditional cohort approach is resource intensive. Wastewater-based epidemiology (WBE) could be an alternative for the traditional approach. This study was to provide the first evaluation to see if WBE can be used to assess the impact of temperature exposure to a population in South East Queensland, Australia using selected pharmaceuticals and personal care products (PPCPs) as biomarkers. Daily loads of eight PPCPs in wastewater collected from a wastewater treatment plant were measured from February 2011 to June 2012...
March 22, 2017: Environmental Research
https://www.readbyqxmd.com/read/28333519/-doctor-are-you-listening-communication-about-children-s-mental-health-and-psychosocial-concerns
#7
Anne E Pidano, Madhavi M Padukkavidana, Lisa Honigfeld
Effective communication is critical, including in the pediatric primary care setting. Pediatric primary care providers (PPCPs) are in a unique position to address psychosocial and mental health concerns during office visits, and effective communication skills play a crucial role in providing an opportunity for parents and patients to disclose and discuss such concerns. In this article, the authors encourage two relatively simple strategies that have shown potential for enhancing effective communication in pediatric primary care regarding mental health and psychosocial issues: (a) ensure that pediatric residents and practicing providers have access to brief, targeted communications training and (b) strongly promote the use of screening tools both to encourage discussion and to assist in identifying children who may benefit from further assessment and/or treatment...
March 2017: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/28300022/optimization-of-a-modified-quechers-method-for-multiresidue-analysis-of-pharmaceuticals-and-personal-care-products-in-sewage-and-surface-water-by-lc-ms-ms
#8
Akanksha S Kachhawaha, Pranav M Nagarnaik, Manjusha Jadhav, Anjali Pudale Pawan K Labhasetwar, Kaushik Banerjee
A quick, sensitive multiresidue method was developed for the analysis of 19 multiclass pharmaceuticals and personal care products (PPCPs) in surface water and sewage water. The proposed modified QuEChERS method involved the extraction of water samples (10 mL) with acetonitrile (10 mL) after the addition of 1% acetic acid, 4 g magnesium sulfate, and 0.2 g ammonium acetate, and was validated in distilled water, surface water, and sewage water with respect to linearity, LOD and LOQ, precision, and accuracy. The LOD and LOQ varied within the ranges of 0...
March 16, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28297635/oh-initiated-transformation-and-hydrolysis-of-aspirin-in-aops-system-dft-and-experimental-studies
#9
Lin He, Xiaomin Sun, Fanping Zhu, Shaojie Ren, Shuguang Wang
Advanced oxidation processes (AOPs) are widely used in wastewater treatment of pharmaceutical and personal care products (PPCPs). In this work, the OH-initiated transformation as well as the hydrolysis of a typical PPCPs, aspirin, was investigated using density functional theory (DFT) calculations and laboratory experiments. For DFT calculations, the frontier electron densities and bond dissociation energies were analyzed. Profiles of the potential energy surface were constructed, and all the possible pathways were discussed...
March 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28292733/rapid-determination-of-54-pharmaceutical-and-personal-care-products-in-fish-samples-using-microwave-assisted-extraction-hollow-fiber-liquid-solid-phase-microextraction
#10
Yi Zhang, Wen Guo, Zhenfeng Yue, Li Lin, Fengjuan Zhao, Peijin Chen, Weidong Wu, Hong Zhu, Bo Yang, Yanyun Kuang, Jiong Wang
In this paper, a simple, rapid, solvent-less and environmental friendliness microextraction method, microwave-assisted extraction-hollow fiber-liquid/solid phase microextraction (MAE-HF-L/SME), was developed for simultaneous extraction and enrichment of 54 trace hydrophilic/lipophilic pharmaceutical and personal care products (PPCPs) from fish samples. A solid-phase extraction material, solid-phase microextraction (SPME) fiber, was synthesized. The SPME fiber had a homogeneous, loose structure and good mechanical properties, and they exhibited a good adsorption capacity for most PPCPs selected...
April 15, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28291611/degradation-kinetics-of-pharmaceuticals-and-personal-care-products-in-surface-waters-photolysis-vs-biodegradation
#11
Rosa María Baena-Nogueras, Eduardo González-Mazo, Pablo A Lara-Martín
Poor removal of many pharmaceuticals and personal care products (PPCPs) in sewage treatment leads to their discharge into the receiving waters, where they may cause negative effects. Their elimination from the water column depends of several processes, including photochemical and biological degradation. We have focused this research on comparing the degradation kinetics of a wide number (n=33) of frequently detected PPCPs considering different types of water, pH and solar irradiation. For those compounds that were susceptible of photodegradation, their rates (k) varied from 0...
March 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28288906/an-aop-analysis-of-selective-serotonin-reuptake-inhibitors-ssris-for-fish
#12
REVIEW
M Danielle McDonald
Pharmaceuticals and personal care products (PPCPs) are found in measureable quantities within the aquatic environment. Selective serotonin reuptake inhibitor (SSRI) antidepressants are one class of pharmaceutical compound that has received a lot of attention. Consistent with most PPCPs, the pharmacokinetics and physiological impacts of SSRI treatment have been well-studied in small mammals and humans and this, combined with the evolutionary conservation of the serotonergic system across vertebrates, allows for the read-across of known SSRI effects in mammals to potential SSRI impacts on aquatic organisms...
March 10, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/28284648/the-relative-risk-and-its-distribution-of-endocrine-disrupting-chemicals-pharmaceuticals-and-personal-care-products-to-freshwater-organisms-in-the-bohai-rim-china
#13
Meng Zhang, Yajuan Shi, Yonglong Lu, Andrew C Johnson, Suriyanarayanan Sarvajayakesavalu, Zhaoyang Liu, Chao Su, Yueqing Zhang, Monika D Juergens, Xiaowei Jin
In this study, the risks to aquatic organisms posed by 12 commonly detected pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) that are extensively used in Bohai coastal region of China were examined. These were linear alkylbenzene sulfonate (LAS), nonylphenol (NP), diethylhexyl phthalate (DEHP), norfloxacin (NOR), sulfamethoxazole (SMX), erythromycin (ERY), bisphenol A (BPA), ofloxacin (OFL), carbamazepine (CBZ), naproxen (NPX), atenolol (ATL) and metoprolol (MET)...
March 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28284644/suitability-of-pharmaceuticals-and-personal-care-products-ppcps-and-artificial-sweeteners-ass-as-wastewater-indicators-in-the-pearl-river-delta-south-china
#14
Yuan-Yuan Yang, Wang-Rong Liu, You-Sheng Liu, Jian-Liang Zhao, Qian-Qian Zhang, Min Zhang, Jin-Na Zhang, Yu-Xia Jiang, Li-Juan Zhang, Guang-Guo Ying
Wastewater indicator is a useful tool for evaluating the wastewater impact on natural water, but there is little information about the suitability of wastewater indicators for different regions. This study aimed to select suitable wastewater indicators in the Pearl River Delta region, south China by screening a range of wastewater related organic compounds. The screening campaign was carried out by investigating the occurrence and removal efficiencies of 93 pharmaceuticals and personal care products (PPCPs) and 5 artificial sweeteners (ASs) in nine wastewater treatment plants (WWTPs) located in the region, and the occurrence of these target compounds in the contaminated and clean surface water of the Pearl River...
March 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28284634/contamination-sources-and-distribution-patterns-of-pharmaceuticals-and-personal-care-products-in-alpine-rivers-strongly-affected-by-tourism
#15
Ladislav Mandaric, Elena Diamantini, Elisa Stella, Karina Cano-Paoli, Jennifer Valle-Sistac, Daniel Molins-Delgado, Alberto Bellin, Gabriele Chiogna, Bruno Majone, M Silvia Diaz-Cruz, Sergi Sabater, Damia Barcelo, Mira Petrovic
Knowledge regarding the impact of tourism on the emergence of pharmaceuticals and personal care products (PPCPs) in Alpine river waters is limited and scarce. Therefore, a study on the occurrence patterns and spatiotemporal variability of 105 PPCPs in an Alpine river basin located in the Trentino-Alto Adige region (North-Eastern Italy) has been conducted. We observed that the total concentration of analyzed PPCPs was generally higher in all sampling sites during winter than in the summer. The analysis of tourist data revealed that during both sampling campaigns the number of tourists was lower in the downstream sites in comparison with the upstream area of the basin (Val di Sole)...
March 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28264771/occurrence-and-ecological-risk-assessment-of-emerging-organic-chemicals-in-urban-rivers-guangzhou-as-a-case-study-in-china
#16
Feng-Jiao Peng, Chang-Gui Pan, Min Zhang, Nai-Sheng Zhang, Ronja Windfeld, Daniel Salvito, Henriette Selck, Paul J Van den Brink, Guang-Guo Ying
Urban rivers may receive contamination from various sources including point sources like domestic sewage and nonpoint sources (e.g., runoff), resulting in contamination with various chemicals. This study investigated the occurrence of emerging organic contaminants (3 endocrine disrupting compounds (EDCs), and 17 pharmaceuticals and personal care products (PPCPs)) in six urban rivers of a representative subtropical city, Guangzhou (southern China). Our results showed that EDCs and personal care products were frequently detected in the water phase and sediment phase...
March 2, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28249192/occurrence-of-pharmaceuticals-and-personal-care-products-in-effluent-dominated-saudi-arabian-coastal-waters-of-the-red-sea
#17
Aasim M Ali, Helene Thorsen Rønning, Walied Alarif, Roland Kallenborn, Sultan S Al-Lihaibi
The occurrence of selected pharmaceuticals and personal care products (PPCPs) and the pesticide atrazine were investigated in seawater samples collected from stations located at effluent dominated sites in the Saudi Arabian coastal waters of the Red Sea. PPCPs were analysed using solid phase extraction (SPE) followed by high performance liquid chromatography - tandem mass spectrometry (HPLC-MS/MS). A multi component method for the ultra-trace level quantification of 13 target PPCPs in Seawater was developed and validated for the here performed study...
May 2017: Chemosphere
https://www.readbyqxmd.com/read/28244310/impact-of-in-sewer-degradation-of-pharmaceutical-and-personal-care-products-ppcps-population-markers-on-a-population-model
#18
Jake William O'Brien, Andrew Phillip William Banks, Andrew Joseph Novic, Jochen F Mueller, Guangming Jiang, Christoph Ort, Geoff Eaglesham, Zhiguo Yuan, Phong K Thai
A key uncertainty of wastewater-based epidemiology is the size of the population which contributed to a given wastewater sample. We previously developed and validated a Bayesian inference model to estimate population size based on 14 population markers which: (1) are easily measured and (2) have mass loads which correlate with population size. However, the potential uncertainty of the model prediction due to in-sewer degradation of these markers was not evaluated. In this study, we addressed this gap by testing their stability under sewer conditions and assessed whether degradation impacts the model estimates...
March 21, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28242224/validation-of-a-method-to-monitor-the-occurrence-of-20-relevant-pharmaceuticals-and-personal-care-products-in-167-bottled-waters
#19
Sophie Lardy-Fontan, Véronique Le Diouron, Catherine Drouin, Béatrice Lalere, Sophie Vaslin-Reimann, Xavier Dauchy, Christophe Rosin
Research on emerging substances in drinking water presents major interest and the possibility of trace contamination has seen increasing concern from the scientific community and the public authorities. More particularly, residues of pharmaceuticals and personal care products (PPCPs) in bottled water are a very important issue due to societal concerns and potential media impact. In this context, it has become necessary to carry out reliable monitoring. This requires measurements of high quality with demonstration of accuracy and well-defined uncertainty...
February 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28202359/preliminary-assessment-on-the-bioaccessibility-of-contaminants-of-emerging-concern-in-raw-and-cooked-seafood
#20
Ricardo N Alves, Ana L Maulvault, Vera L Barbosa, Sara Cunha, Christiaan J A F Kwadijk, Diana Álvarez-Muñoz, Sara Rodríguez-Mozaz, Òscar Aznar-Alemany, Ethel Eljarrat, Damià Barceló, Margarita Fernandez-Tejedor, Alice Tediosi, António Marques
A preliminary assessment of the bioaccessibility of contaminants of emerging concern (CeCs), including perfluorinated compounds (PFCs; i.e. PFOS and PFUnA), brominated flame retardants (BFRs; i.e. BDE47, BDE100, α-HBCD) and pharmaceuticals and personal care products (PPCPs; i.e. venlafaxine, methylparaben and UV-filter OC) was performed in seafood species available in the European markets. Additionally, the effect of steaming on CeCs bioaccessibility was also investigated for the first time. Overall, steaming affected differentially contaminants' concentrations, for instance, decreasing PFOS levels in flounder, but increasing both BDE47 and BDE100...
February 13, 2017: Food and Chemical Toxicology
keyword
keyword
64789
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"