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https://www.readbyqxmd.com/read/28449254/bioresorbable-fe-mn-and-fe-mn-ha-materials-for-orthopedic-implantation-enhancing-degradation-through-porosity-control
#1
Michael Heiden, Eric Nauman, Lia Stanciu
Resorbable, porous iron-manganese-hydroxyapatite biocomposites with suitable degradation rates for orthopedic applications are prepared using salt-leaching for the first time. These transient biomaterials have the potential to replace inert, permanent implants that can suffer from long-term complications, or have to be surgically removed, leaving an unfavorable void. Fe30Mn-10HA materials are newly developed to address inadequate resorption rates of degradable materials proposed for orthopedic environments in the past...
April 27, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28444441/the-activity-of-the-rectal-gland-of-the-north-pacific-spiny-dogfish-squalus-suckleyi-is-glucose-dependent-and-stimulated-by-glucagon-like-peptide-1
#2
Courtney A Deck, W Gary Anderson, J Michael Conlon, Patrick J Walsh
Elasmobranchs possess a specialised organ, the rectal gland, which is responsible for excreting sodium chloride via the posterior intestine. Previous work has indicated that the gland may be activated by a number of hormones, some of which are likely related to the salt or volume loads associated with feeding. Furthermore, evidence exists for the gland being glucose dependent which is atypical for an elasmobranch tissue. In this study, the presence of sodium-glucose co-transporters (SGLTs) in the rectal gland and their regulation by feeding were investigated...
April 25, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/28443102/effect-of-hbdhn1-and-hbdhn2-genes-on-abiotic-stress-responses-in-arabidopsis
#3
Yuxin Cao, Xian Xiang, Mengting Geng, Qin You, Xi Huang
Dehydrin is a type of late embryogenesis abundant (LEA) protein. The dehydrin genes, HbDHN1 and HbDHN2, in Hevea brasiliensis were previously found to be induced at the wounding site of epicormic shoots, with local tissue dehydration identified as the key signal for laticifer differentiation. However, the exact role of the HbDHNs remains unknown. In this study, HbDHN1 and HbDHN2 expression was examined under multiple abiotic stresses; namely, cold, salt, drought, wounding, abscisic acid (ABA), ethylene (ET), and jasmonic acid (JA) treatment...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28441792/urinary-iodine-concentrations-in-cancer-patients
#4
Saeed Kargar, Seyed Mostafa Shiryazdi, Seyed Reza Atashi, Hossein Neamatzadeh, Mahdieh Kamali
Background: It has been suggested that incidence of some cancers, especially examples in the breast and stomach may be influenced by the iodine intake. However, only few studies are available at present. Therefore, we have conducted the present assessment of iodine status in Iranian patients diagnosed with a malignancy. Materials and Methods: This cross-sectional study was conducted in 85 patients diagnosed with different types of cancer at Shahid Sadoughi Hospital, Yazd, Iran. The method used was based on the Sandell–Kolthoff reaction...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28441726/sodium-and-potassium-intake-in-healthy-adults-in-thessaloniki-greater-metropolitan-area-the-salt-intake-in-northern-greece-sing-study
#5
Eleni Vasara, Georgios Marakis, Joao Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos Rodopaios, Alexandra A Koulouri, Francesco P Cappuccio
A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High potassium intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and potassium intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and potassium intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium intakes or sodium-to-potassium ratio...
April 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28441407/changes-in-secondary-metabolites-in-the-halophytic-putative-crop-species-crithmum-maritimum-l-triglochin-maritima-l-and-halimione-portulacoides-l-aellen-as-reaction-to-mild-salinity
#6
Christian Boestfleisch, Jutta Papenbrock
It is assumed that salinity enhances the concentration of valuable metabolites in halophytes. The objective was to find a salt concentration and a point in time at which the yield for the valuable metabolites was maximal. Therefore, three different halophyte species were grown under different salinities and harvested over a period from shortly after stress induction up to three weeks. Various reaction patterns were found in the metabolite composition of the analyzed plant material. Halimione portulacoides showed a "short term response", indicated by an increase in all metabolites analyzed after a few hours, whereas Crithmum maritimum showed a "long term response" through accumulation of proline starting after days...
2017: PloS One
https://www.readbyqxmd.com/read/28440836/controllable-hydrothermal-synthesis-of-ni-h-bea-with-a-hierarchical-core-shell-structure-and-highly-enhanced-biomass-hydrodeoxygenation-performance
#7
Bing Ma, Huimei Cui, Darui Wang, Peng Wu, Chen Zhao
Ni based catalysts are wildly used in catalytic industrial processes due to their low costs and high activities. The design of highly hierarchical core-shell structured Ni/HBEA is achieved using a sustainable, simple, and easy-tunable hydrothermal synthesis approach using combined NH4Cl and NH3·H2O as a co-precipitation agent at 120 °C. Starting from a single-crystalline hierarchical H(+)-exchanged beta polymorph zeolite (HBEA), the adjustment of the precipitate conditions shows that mixed NH4Cl and NH3·H2O precipitates with proper concentrations are vital in the hydrothermal synthesis for preserving a good crystalline morphology of HBEA and generating abundant highly-dispersed Ni nanoparticles (loading: 41 wt%, 5...
April 25, 2017: Nanoscale
https://www.readbyqxmd.com/read/28438314/progression-of-experimental-autoimmune-encephalomyelitis-is-associated-with-up-regulation-of-major-sodium-transporters-in-the-mouse-kidney-cortex-under-a-normal-salt-diet
#8
Xiaoming Zhou, Balamurugan Packialakshmi, Yao Xiao, Saule Nurmukhambetova, Jason R Lees
Recent demonstrations of exacerbation of experimental autoimmune encephalomyelitis (EAE) by high salt diets prompted us to study whether EAE stimulated Na absorption by the renal cortex, a primary regulatory site for Na balance, even under a normal NaCl diet. We found that as EAE progressed from mild to severe symptoms, there were parallel increases in the protein abundance of NHE3 and αENaC and the Na,K-ATPase activity with an affiliated elevation of its β1-subunit protein. These effects are associated with increases in the protein levels of the well-known regulators SGK1 and scaffold NHERF2, and phosphorylation of ERK1/2...
April 18, 2017: Cellular Immunology
https://www.readbyqxmd.com/read/28437860/chronic-inhibition-of-fatty-acid-amide-hydrolase-by-urb597-produces-differential-effects-on-cardiac-performance-in-normotensive-and-hypertensive-rats
#9
Anna Pedzinska-Betiuk, Jolanta Weresa, Marek Toczek, Marta Baranowska-Kuczko, Irena Kasacka, Ewa Harasim-Symbor, Barbara Malinowska
BACKGROUND AND PURPOSE: Fatty acid amide hydrolase (FAAH) inhibitors are postulated to possess anti-hypertensive potential, because their acute injection decreases blood pressure (BP) in spontaneously hypertensive rats (SHR) partially through normalization of cardiac contractile function. Here, we examined whether the potential hypotensive effect of chronic FAAH inhibition by URB597 in hypertensive rats correlates with changes in cardiac performance. EXPERIMENTAL APPROACH: Experiments were performed using perfused hearts and left atria isolated from 8-10 week old SHR, age-matched deoxycorticosterone acetate (DOCA-salt) rats and normotensive controls chronically treated with URB597 (1 mg kg(-1) ) or vehicle...
April 24, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28437742/biological-treatment-of-model-dyes-and-textile-wastewaters
#10
Alicia Paz, Julia Carballo, María José Pérez, José Manuel Domínguez
Previous works conducted in our laboratory, reveled that Bacillus aryabhattai DC100 produce ligninolytic enzymes such as laccases and/or peroxidases, opening new applications in different bioprocesses, including the treatment of disposal residues such as dyestuffs from textile processing industries. This work described the degradation of three commercial model dyes Coomassie Brilliant Blue G-250 (CBB), Indigo Carmine (IC) and Remazol Brilliant Blue R (RBBR) under different culture media and operational conditions...
April 18, 2017: Chemosphere
https://www.readbyqxmd.com/read/28436654/crystal-phase-transitions-and-photocatalysis-in-supramolecular-scaffolds
#11
Roman V Kazantsev, Adam J Dannenhoffer, Adam S Weingarten, Brian T Phelan, Boris Harutyunyan, Taner Aytun, Ashwin Narayanan, Daniel J Fairfield, Job Boekhoven, Hiroaki Sai, Andrew Senesi, Pascual I O'Dogherty, Liam C Palmer, Michael J Bedzyk, Michael R Wasielewski, Samuel I Stupp
The energy landscape of a supramolecular material can include different molecular packing configurations that differ in stability and function. We report here on a thermally driven crystalline order transition in the landscape of supramolecular nanostructures formed by charged chromophore amphiphiles in salt-containing aqueous solutions. An irreversible transition was observed from a metastable to a stable crystal phase within the nanostructures. In the stable crystalline phase, the molecules end up organized in a short scroll morphology at high ionic strengths and as long helical ribbons at lower salt content...
April 24, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28434242/-hungarian-diet-and-nutritional-status-survey-ot%C3%A3-p2014-iii-macroelement-intake-of-the-hungarian-population
#12
Barbara Nagy, Zsuzsanna Nagy-Lőrincz, Márta Bakacs, Éva Illés, Eszter Sarkadi Nagy, Éva Martos
INTRODUCTION AND AIM: The Hungarian Diet and Nutritional Status Survey examined the dietary habits of the Hungarian adult population. The aim of the study is to present the macroelement intake of the population. METHOD: The study represents the macrolement intake of the population with age 18 or over on the day of 31 December 2013, of those who are non-institutionalised. RESULTS: Salt intake decreased compared to the findings of the previous study in 2009 but it is still extremely high (15...
April 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28433661/differential-protein-acetylation-assists-import-of-excess-sod2-into-mitochondria-and-mediates-sod2-aggregation-associated-with-cardiac-hypertrophy-in-the-murine-sod2-tg-heart
#13
Liwen Zhang, Chwen-Lih Chen, Patrick T Kang, Zhicheng Jin, Yeong-Renn Chen
SOD2 is the primary antioxidant enzyme neutralizing ((•))O2((-)) in mitochondria. Cardiac-specific SOD2 overexpression (SOD2-tg) induces supernormal function and cardiac hypertrophy in the mouse heart. However, the reductive stress imposed by SOD2 overexpression results in protein aggregation of SOD2 pentamers and differential hyperacetylation of SOD2 in the mitochondria and cytosol. Here, we studied SOD2 acetylation in SOD2-tg and wild-type mouse hearts. LC-MS/MS analysis indicated the presence of four acetylated lysines in matrix SOD2 and nine acetylated lysines in cytosolic SOD2 from the SOD2-tg heart...
April 19, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28431384/sediment-and-salinity-effects-on-the-bioaccumulation-of-sulfamethoxazole-in-zebrafish-danio-rerio
#14
Y Chen, J L Zhou, L Cheng, Y Y Zheng, J Xu
The dynamic distribution of a widely used antibiotic sulfamethoxazole between water, sediment and aquatic organisms (zebrafish) was studied in microcosms. Sulfamethoxazole concentrations in water were gradually reduced, while in sediment and zebrafish gradually increased, suggesting active adsorption and bioaccumulation processes occurring. The presence of sediment particles and their interactions with water reduced the bioaccumulation of sulfamethoxazole in zebrafish by 13-28%. The sediment of smaller particle size with more organic carbon content and higher surface area, adsorbed sulfamethoxazole more extensively and decreased its bioaccumulation most significantly...
April 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28430843/carotid-body-denervation-markedly-improves-survival-in-rats-with-hypertensive-heart-failure
#15
Kana Fujii, Keita Saku, Takuya Kishi, Yasuhiro Oga, Takeshi Tohyama, Takuya Nishikawa, Takafumi Sakamoto, Masataka Ikeda, Tomomi Ide, Hiroyuki Tsutsui, Kenji Sunagawa
BACKGROUND: Hypertension is a major cause of heart failure. Excessive sympathoexcitation in patients with heart failure leads to poor prognosis. Since carotid body denervation (CBD) has been shown to reduce sympathetic nerve activity in animal models of hypertension and heart failure, we examined if bilateral CBD attenuates the progression of hypertensive heart failure and improves survival. METHODS: We randomly allocated Dahl salt-sensitive rats fed a high-salt diet from 6 weeks of age into CBD (n = 31) and sham-operation (SHAM; n = 50) groups, and conducted CBD or SHAM at 7 weeks of age...
April 19, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28429470/meta-analysis-combining-parallel-and-cross-over-trials-with-random-effects
#16
François Curtin
Meta-analysis can necessitate the combination of parallel and cross-over trial designs. Because of the differences in the trial designs and potential biases notably associated with the crossover trials, one often combines trials of the same designs only, which decreases the power of the meta-analysis. To combine results of clinical trials from parallel and cross-over designs, we extend the method proposed in an accompanying study to account for random effects. We propose here a hierarchical mixed model allowing the combination of the 2 types of trial designs and accounting for additional covariates where random effects can be introduced to account for heterogeneity in trial, treatment effect, and interactions...
April 21, 2017: Research Synthesis Methods
https://www.readbyqxmd.com/read/28429019/facile-syntheses-of-pure-uranium-halides-ucl4-ubr4-and-ui4
#17
Stefan S Rudel, Florian Kraus
Herein we describe convenient lab scale syntheses of several uranium(iv) halides of high purity by reaction of AlX3 (X = Cl, Br and I) with UO2, which is readily available by reduction of uranyl salts like UO2(NO3)2·6H2O. UCl4, UBr4, and UI4 are obtained in the form of aggregates of large single crystals. Their identities and purity were checked by powder X-ray diffraction, IR spectroscopy and elemental analysis. The syntheses introduced here avoid the need for pure metallic uranium and are based on more readily available starting materials, UO2, which does not even have to be pure, and the respective aluminium halide...
April 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28427673/sonocatalytic-rapid-degradation-of-congo-red-dye-from-aqueous-solution-using-magnetic-fe-0-polyaniline-nanofibers
#18
Raghunath Das, Madhumita Bhaumik, Somnath Giri, Arjun Maity
Nano-sized magnetic Fe(0)/polyaniline (Fe(0)/PANI) nanofibers were used as an effective material for sonocatalytic degradation of organic anionic Congo red (CR) dye. Fe(0)/PANI, was synthesized via reductive deposition of nano-Fe(0) onto the PANI nanofibers at room temperature. Prepared catalyst was characterized using HR-TEM, FE-SEM, XRD, FTIR instruments. The efficacy of catalyst in removing CR was assessed colorimetrically using UV-visible spectroscopy under different experimental conditions such as % of Fe(0) loading into the composite material, solution pH, initial concentration of dye, catalyst dosage, temperature and ultrasonic power...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28426213/role-of-mediator-and-effects-of-temperature-on-ortho-c-n-bond-fusion-reactions-of-aniline-using-ruthenium-templates-isolation-and-characterization-of-new-ruthenium-complexes-of-the-in-situ-generated-ligands
#19
Suman K Roy, Debabrata Sengupta, Santi Prasad Rath, Tanushri Saha, Subhas Samanta, Sreebrata Goswami
In this work, ortho-C-N bond fusion reactions of aniline are followed by the use of two different ruthenium mediators. Reaction of aniline with [Ru(III)(terpy)Cl3] (terpy = 2,2':6',2″-terpyridine) resulted in a trans bis-aniline ruthenium(II) complex [1](+) which upon oxidation with H2O2 produced compound [2](+) of a bidentate ligand, N-phenyl-1,2-benzoquinonediimine, due to an oxidative ortho-C-N bond fusion reaction. Complex [1](+) and aniline (neat) at 185 °C produced a bis-chelated ruthenium complex (3)...
April 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28425705/facile-aqueous-phase-synthesis-of-ptau-bi2o3-hybrid-catalyst-for-efficient-electro-oxidation-of-ethanol
#20
Sumanta Sarkar, Rajkumar Jana, Hiranmayee Vadlamani, Swetha Ramani, Dundappa Mumbaraddi, Sebastian C Peter
In this work, we present a facile aqueous phase synthesis of a hybrid catalyst consists of PtAu alloy supported on Bi2O3 microspheres. Multistep reduction of HAuCl4 and K2PtCl4 salts on Bi2O3 and subsequent annealing leads to the formation of this hybrid catalyst. To the best of our knowledge, this is the first report of using Bi2O3 as a catalyst support in Fuel cell applications. The material was characterized by powder X-ray diffraction and various microscopic techniques. This composite showed remarkable activity as well as stability towards the electro-oxidation of ethanol in comparison to commercially available Pt/C...
April 20, 2017: ACS Applied Materials & Interfaces
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