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https://www.readbyqxmd.com/read/28531232/changes-in-primary-healthcare-providers-attitudes-and-counseling-behaviors-related-to-dietary-sodium-reduction-docstyles-2010-and-2015
#1
Zerleen S Quader, Mary E Cogswell, Jing Fang, Sallyann M Coleman King, Robert K Merritt
High blood pressure is a major risk factor for cardiovascular disease. The 2013 ACC/AHA Lifestyle Management Guideline recommends counseling pre-hypertensive and hypertensive patients to reduce sodium intake. Population sodium reduction efforts have been introduced in recent years, and dietary guidelines continued to emphasize sodium reduction in 2010 and 2015. The objective of this analysis was to determine changes in primary health care providers' sodium-reduction attitudes and counseling between 2010 and 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28530195/facile-synthesis-of-silver-nanoparticles-mediated-by-polyacrylamide-reduction-approach-to-antibacterial-application
#2
Hosam I Salaheldin, Meshal H K Almalki, Abd Elhameed M Hezma, Gamal E H Osman
The current time increase in the prevalence of antibiotic resistant 'super-bugs' and the risks associated with food safety have become global issues. Therefore, further research is warranted to identify new and effective antimicrobial substances. Silver nanoparticles (Ag-NPs) were synthesized by autoclaving technique using, different concentrations of Ag salt (AgNO3) solution (1, 5, 10, and 25 mM). Their presence was confirmed by a surface plasmon resonance band at ∼435 nm using UV-Vis absorption spectra...
June 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28529591/antitumor-activity-of-7-o-succinyl-macrolactin-a-tromethamine-salt-in-the-mouse-glioma-model
#3
Jun Jin, Suh Hee Choi, Jung Eun Lee, Jin-Deok Joo, Jung Ho Han, Su-Young Park, Chae-Yong Kim
Chemoradiotherapy with temozolomide is the current standard treatment option for patients with glioblastoma. However, the majority of patients with glioblastoma survive for <2 years. Therefore, it is necessary to develop more effective therapeutic strategies for the treatment of glioblastoma. 7-O-succinyl macrolactin A tromethamine salt (SMA salt), a macrolactin compound, is known to possess an antiangiogenic activity. The present study investigated the antitumor effects of SMA salt in the treatment of glioblastoma by evaluating in vitro and in vivo antitumor effects of SMA salt in an experimental glioblastoma model...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28528213/optimal-electrostatic-interactions-between-substrate-and-protein-are-essential-for-radical-chemistry-in-ornithine-4-5-aminomutase
#4
Caitlyn Makins, Douglas A Whitelaw, Michael McGregor, Alix Petit, Robert G Mothersole, Kathleen E Prosser, Kirsten R Wolthers
Ornithine 4,5-aminomutase (OAM) from Clostridium sticklandii is an adenosylcobalamin (AdoCbl) and pyridoxal 5'-phosphate (PLP)-dependent enzyme that catalyzes a 1,2-amino shift, interconverting D-ornithine and 2S, 4R-diaminopentanoate. The reaction occurs via a radical-based mechanism whereby a PLP-bound substrate radical undergoes intramolecular isomerization via an azacyclopropylcarbinyl radical intermediate. Herein, we investigated the catalytic role of active site residues that form non-covalent interactions with PLP and/or substrate, D-ornithine...
May 17, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28526345/facile-fabrication-of-3d-porous-hybrid-sphere-by-co-immobilization-of-multi-enzyme-directly-from-cell-lysates-as-an-efficient-and-recyclable-biocatalyst-for-asymmetric-reduction-with-coenzyme-regeneration-in-situ
#5
MinganYu, Duqiang Liu, Lili Sun, Jing Li, Qian Chen, Lijun Pan, Jingchuan Shang, Shurong Zhang, Wei Li
Ni(2+)-agarose bead-wrapped multi-enzyme/inorganic hybrid sphere composed of the immobilized enzymes as organic component and NaH2PO4 and NaCl as inorganic component was developed by co-immobilizing extracellular His-tagged 3-quinuclidinone reductases and glucose dehydrogenase without pre-purification. The resulting biocatalysts has 3D porous architectures as confirmed by SEM and FESEM, and it enabled the continuous biotransformation of 3-quinuclidone to (R)-3-quinuclidinol with cofactor regeneration in situ...
May 16, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28524742/piqueria-trinervia-as-a-source-of-metabolites-against-giardia-intestinalis
#6
Yadira Rufino-González, Martha Ponce-Macotela, Manuel Jiménez-Estrada, Candy N Jiménez-Fragoso, Guadalupe Palencia, Gabriel Sansón-Romero, Anahi Anzo-Osorio, Mario N Martínez-Gordillo
CONTEXT: Piqueria trinervia Cav. (Asteraceae) is a plant species with a long history in traditional medicine to cure diarrhoea and other digestive disorders. OBJECTIVE: The study investigates the antigiardial activity of piquerol, trinervinol, red oil and two fractions (F1 and F2) from P. trinervia. MATERIALS AND METHODS: P. trinervia was collected in the Ajusco in Mexico City. Aerial parts were ground and mixed with water to obtain the extract, which was treated with dichloromethane to isolate piquerol and trinervinol (P & T)...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28521233/fouling-reduction-using-adsorbents-flocculants-in-a-submerged-anaerobic-membrane-bioreactor
#7
Qiaoyun Zhang, Suniti Singh, David C Stuckey
Using adsorbents/flocculants in anaerobic membrane bioreactors (AnMBRs) to reduce membrane fouling is comparatively rare. This study evaluated 8 additives: 3 powdered activated carbons, 2 granular activated carbons, 1 cationic polymer, and 2 metal salts to identify the best additive and dose to minimise membrane fouling. Small cross flow filtration tests showed 400mg/L PAC SAE2, or 150mg/L FeCl3, reduced the transmembrane pressure (TMP) rise from 0.94 to 0.06kPa/h, indicating excellent fouling reduction. The best filtration performance correlated with a significant reduction in supernatant supracolloidal particles, colloids and SMPs...
May 5, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28516760/from-highly-fluorescent-donors-to-strongly-absorbing-acceptors-the-tunable-properties-of-fluorubines
#8
Dominique Mario Gampe, Stefan Schramm, Steffen Ziemann, Matthias Westerhausen, Helmar Görls, Pance Naumov, Rainer Beckert
The synthesis and characterization of three novel fluorubine derivatives is reported via three to four simple reaction steps with isolatable intermediates. The functional dyes are characterized by their strong absorption peaks in the visible region and high fluorescence quantum yields. A significant and useful feature is that the properties can be tuned over a wide range by changing the pH. Transformation of the dyes into protonated amidinium salts leads to narrower band gaps and drastically lower LUMO energies...
May 18, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28514901/fixed-bed-study-for-bone-char-adsorptive-removal-of-refractory-organics-from-electrodialysis-concentrate-produced-by-petroleum-refinery
#9
Patrícia da Luz Mesquita, Cássia Ribeiro Souza, Nilza Tatiane G Santos, Sônia Denise Ferreira Rocha
Water reuse in industrial processes has been an increasing need encouraged in recent years. However, as the streams are recycled, solutes accumulate, thus requiring purification techniques. Membrane processes (reverse osmosis and electrodialysis) have been implemented and in order to increase the reuse of water at its highest level, crystallization has been evaluated to remove salts from the concentrate produced and get a feasible disposal. Nevertheless, contaminants affect the crystallization performance, thus making the removal of residual organics important for both, the efficiency of crystallization as well as the increase of water reuse...
May 17, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28512108/clinical-relevance-and-role-of-neuronal-at1-receptors-in-adam17-mediated-ace2-shedding-in-neurogenic-hypertension
#10
Jiaxi Xu, Srinivas Sriramula, Huijing Xia, Lisa Moreno-Walton, Frank Culicchia, Oliver Domenig, Marko Poglitsch, Eric Lazartigues
Rationale: Neurogenic hypertension is characterized by an increase in sympathetic activity and often resistance to drug treatments. We previously reported that it is also associated with a reduction of Angiotensin Converting Enzyme 2 (ACE2) and an increase in A Disintegrin And Metalloprotease 17 (ADAM17) activity in experimental hypertension. In addition, while multiple cells within the central nervous system have been involved in the development of neurogenic hypertension, the contribution of ADAM17 has not been investigated...
May 16, 2017: Circulation Research
https://www.readbyqxmd.com/read/28507723/p-doping-of-graphene-in-hybrid-materials-with-3-10-diazapicenium-dications
#11
Alexandra Roth, Tobias A Schaub, Ute Meinhardt, Dominik Thiel, Jan Storch, Vladimír Církva, Pavel Jakubík, Dirk M Guldi, Milan Kivala
N,N'-Didodecyl-substituted 3,10-diazapicenium salts featuring bromide and hexafluorophosphate counterions have been designed as novel dopants to realize individualized graphene sheets in a series of cutting edge experiments and to intrinsically stabilize them via p-doping. Importantly, electrochemical studies revealed two consecutive irreversible one-electron reductions of the N,N'-didodecyl-substituted 3,10-diazapicenium salts to yield the corresponding radical cation and neutral quinoidal species. Formation of both species was accompanied by characteristic changes in the absorption spectra...
May 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28504878/raspberry-like-nanostructured-silicon-composite-anode-for-high-performance-lithium-ion-batteries
#12
Shan Fang, Zhenkun Tong, Ping Nie, Gao Liu, Xiaogang Zhang
Adjusting the particle size and nanostructure or applying carbon materials as the coating layers are promising to hold the volume expansion of Si in order for its practical application in lithium ion batteries (LIBs). Herein, the mild carbon-coating combined with a molten salt reduction is precisely designed to synthesize a raspberry-like hollow Silicon spheres coated with carbon shells (HSi@C) as the anode materials for LIBs. The HSi@C exhibits a remarkable electrochemical performance, a high reversible specific capacity of 886...
May 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28502049/evaluation-of-carbofuran-mediated-toxicity-against-human-lymphocytes-and-red-blood-cells-in-simulated-wastewater-degraded-by-coagulation-flocculation
#13
Roli Saini, Pradeep Kumar, Sumit Kumar Hira, Partha Pratim Manna
Coagulation-flocculation in water treatment has been relied upon aluminum (Al) and iron (Fe) salts for treatment of contaminants present in source waters containing dissolved organic compounds. However, water quality deteriorates day by day which makes it urgent to improve the standards of the treatment procedure. Coagulation-flocculation-sedimentation performance of ferric chloride and alum was comparatively investigated for carbofuran treatment in simulated wastewater. Coagulation trails were performed in a jar test at several pH levels and coagulant doses to determine reduction efficiencies of carbofuran degradation and chemical oxygen demand (COD)...
May 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28497960/using-dynamic-covalent-chemistry-to-drive-morphological-transitions-controlled-release-of-encapsulated-nanoparticles-from-block-copolymer-vesicles
#14
Renhua Deng, Matthew J Derry, Charlotte J Mable, Yin Ning, Steven P Armes
Dynamic covalent chemistry is exploited to drive morphological order-order transitions to achieve the controlled release of a model payload (e.g., silica nanoparticles) encapsulated within block copolymer vesicles. More specifically, poly(glycerol monomethacrylate)-poly(2-hydroxypropyl methacrylate) (PGMA-PHPMA) diblock copolymer vesicles were prepared via aqueous polymerization-induced self-assembly in either the presence or absence of silica nanoparticles. Addition of 3-aminophenylboronic acid (APBA) to such vesicles results in specific binding of this reagent to some of the pendent cis-diol groups on the hydrophilic PGMA chains to form phenylboronate ester bonds in mildly alkaline aqueous solution (pH ∼ 10)...
May 23, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28494444/associations-of-usual-24-hour-sodium-and-potassium-intakes-with-blood-pressure-and-risk-of-hypertension-among-adults-in-china-s-shandong-and-jiangsu-provinces
#15
Jianwei Xu, Xiaorong Chen, Zeng Ge, Hao Liang, Liuxia Yan, Xiaolei Guo, Yongqing Zhang, Linhong Wang, Jixiang Ma
BACKGROUND/AIMS: High sodium intake and low intake of potassium can increase blood pressure (BP) and risk of developing hypertension. Few studies have examined the association between 24-h urinary sodium and potassium excretion and BP or risk of hypertension in China, and most used only a single 24-h urinary sample. METHODS: We analyzed data on 2281 participants aged 18-69 years by using two 24-h urinary sodium and potassium excretions from the supplemental baseline survey of the Shandong-Ministry of Health Action on Salt Reduction and Hypertension (SMASH) project...
2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28494363/reductive-solidification-stabilization-of-chromate-in-municipal-solid-waste-incineration-fly-ash-by-ascorbic-acid-and-blast-furnace-slag
#16
Xian Zhou, Min Zhou, Xian Wu, Yi Han, Junjun Geng, Teng Wang, Sha Wan, Haobo Hou
Fly ash is a hazardous byproduct of municipal solid waste incineration (MSWI). Cementitious material that is based on ground-granulated blast furnace slag (GGBFS) has been tested and proposed as a binder to stabilize Pb, Cd, and Zn in MSWI fly ash (FA). Cr, however, still easily leaches from MSWI FA. Different reagents, such as ascorbic acid (VC), NaAlO2, and trisodium salt nonahydrate, were investigated as potential Cr stabilizers. The results of the toxicity characteristic leaching procedure (TCLP) showed that VC significantly improved the stabilization of Cr via the reduction of Cr(VI) to Cr(III)...
April 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28494317/consumer-evaluations-of-processed-meat-products-reformulated-to-be-healthier-a-conjoint-analysis-study
#17
Liran C Shan, Aoife De Brún, Maeve Henchion, Chenguang Li, Celine Murrin, Patrick G Wall, Frank J Monahan
Recent innovations in processed meats focus on healthier reformulations through reducing negative constituents and/or adding health beneficial ingredients. This study explored the influence of base meat product (ham, sausages, beef burger), salt and/or fat content (reduced or not), healthy ingredients (omega 3, vitamin E, none), and price (average or higher than average) on consumers' purchase intention and quality judgement of processed meats. A survey (n=481) using conjoint methodology and cluster analysis was conducted...
May 1, 2017: Meat Science
https://www.readbyqxmd.com/read/28492325/theoretical-study-of-the-solvation-effect-on-the-reductive-reaction-of-vinylene-carbonate-in-the-electrolyte-solution-of-lithium-ion-batteries
#18
Kento Kasahara, Hiroshi Nakano, Hirofumi Sato
Carbon monoxide generation reaction of vinylene carbonate (VC) in the electrolyte solution of lithium ion batteries (ethylene carbonate (EC) and 1.0 M LiClO4/EC) is studied using the RISM-SCF-SEDD method, a hybrid methodology of statistical mechanics for molecular liquids and quantum chemistry. The analytical treatment of the solvent and lithium salt enables us to treat the complicated composition of the solution such as the concentration of the salt which is difficult for the methods based on the molecular dynamics (MD) simulation...
May 11, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28488436/fine-co-nanoparticles-encapsulated-in-n-doped-porous-carbon-matrix-with-superficial-n-doped-porous-carbon-nanofibers-for-efficient-oxygen-reduction
#19
Xiao Ma, Xue Zhao, Jianshe Huang, Litai Sun, Qun Li, Xiurong Yang
Herein, we develop a novel method to synthesize evenly dispersed fine Co nanoparticles (NPs) (particle size of ~ 42 nm) encapsulated in N-doped porous carbon matrix (NPCM) with superficial N-doped porous carbon nanofibers (NPCNF) (denoted as Co@NPCM/CNF-850) as an oxygen reduction reaction (ORR) electrocatalyst. Such electrocatalyst is the direct pyrolysis product of the novel pine needle-like ZIF-67-based metal-organic framework nanowire array (MOFNWA) prepared by inorganic cobalt carbonate hydroxide (Co(CO3)0...
May 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28488226/the-prevalence-of-antibiotic-resistant-bacteria-arb-in-waters-of-the-lower-ballona-creek-watershed-los-angeles-county-california
#20
Stephanie Kawecki, Gary Kuleck, John H Dorsey, Christopher Leary, Michelle Lum
Screening for the prevalence of antibiotic-resistant bacteria (ARB) was done at the Ballona Creek and Wetlands, an urban-impacted wetland system in Los Angeles, California. The goals were (1) to assess the overall prevalence of ARB, and (2) compare differences in ARB abundance and the types of antibiotic resistance (AR) among the following sample types: lagoon water from Del Rey Lagoon, urban runoff from Ballona Creek, and water from the Ballona Wetlands (tidal water flooding in from the adjacent estuary, and ebbing out from the salt marsh)...
June 2017: Environmental Monitoring and Assessment
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