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https://www.readbyqxmd.com/read/27916450/dramatic-response-after-functional-hemispherectomy-in-a-patient-with-epileptic-encephalopathy-carrying-a-de-novo-col4a1-mutation
#1
Naomi Hino-Fukuyo, Atsuo Kikuchi, Masaki Iwasaki, Yuko Sato, Yuki Kubota, Tomoko Kobayashi, Tojo Nakayama, Kazuhiro Haginoya, Natsuko Arai-Ichinoi, Tetsuya Niihori, Ryo Sato, Tasuku Suzuki, Hiroki Kudo, Ryo Funayama, Keiko Nakayama, Yoko Aoki, Shigeo Kure
We describe the first case of a successful functional hemispherectomy in a patient with epileptic encephalopathy and a de novo collagen type IV alpha 1 (COL4A1) mutation. A 4-year-old girl was COL4A1 mutation-positive and suffered from drug-resistant epilepsy, hemiplegia, and developmental delay. Magnetic resonance imaging detected no porencephaly, and she had no cataract or renal abnormality. Following a presurgical evaluation for epilepsy, she underwent a functional hemispherectomy. She has been seizure free with no intracranial hemorrhage or other perioperative complications...
December 1, 2016: Brain & Development
https://www.readbyqxmd.com/read/27913085/anti-n-methyl-d-aspartate-receptor-encephalitis-and-rasmussen-like-syndrome-an-association
#2
Kevin Gurcharran, Shefali Karkare
BACKGROUND: N-methyl-D-aspartate (NMDA) receptor encephalitis is an immune-mediated condition that has a broad spectrum of manifestations, including seizures, coma, psychosis, and focal neurological deficits. Although usually a diffuse process, unihemispheric involvement mimicking early stages of Rasmussen encephalitis can occur. Rasmussen's encephalitis is a unique syndrome characterized by progressive hemiplegia, drug-resistant focal epilepsy, cognitive decline, and hemispheric brain atrophy contralateral to the hemiplegia...
October 11, 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/27909274/-three-mitral-valve-operations-in-a-patient-with-trousseau-syndrome-and-nonbacterial-thrombotic-endocarditis-caused-by-ovarian-cancer
#3
Masahito Saito, Naoki Asano, Kazunori Ota, Kazuho Niimi, Koyu Tanaka, Shigeyoshi Gon, Hiroshi Takano
A 52-year-old woman was admitted to our hospital for acute right hemi-paresis, left homonymous hemianopia, and fever. Magnetic resonance imaging of the brain showed multiple cerebral infarctions and transesophageal echocardiography (TEE) revealed a vegetation on the posterior leaflet of her mitral valve. Mitral valve repair was performed under a diagnosis of infective endocarditis (IE). Further multiple cerebral infarctions occurred on the 11th postoperative day, resulting in left hemiplegia and dysarthria...
December 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27907872/does-unilateral-single-event-multilevel-surgery-improve-gait-in-children-with-spastic-hemiplegia-a-retrospective-analysis-of-a-long-term-follow-up
#4
Christian Schranz, Annika Kruse, Tanja Kraus, Gerhardt Steinwender, Martin Svehlik
Single event multilevel surgery (SEMLS) has become a standard intervention for children with cerebral palsy (CP). SEMLS proved to improve the gait in bilateral spastic cerebral palsy and those improvements can be maintained in the long term. However there is no evidence on the long-term outcome of unilateral SEMLS in children with unilateral spastic cerebral palsy. The gait analyses and clinical data of 14 children (9 male/5 female, mean age 12.1) with unilateral CP (6 children Gross Motor Function Classification System Scale level I and 8 children level II) were retrospectively reviewed at four time-points: preoperatively, 1year, 3-5 years and approximately 10 years after unilateral SEMLS...
November 15, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27893159/modified-technique-for-common-carotid-artery-transposition-in-standing-horses
#5
Heidi Tapio, David Argüelles, Luis A Gracia-Calvo, Marja Raekallio
OBJECTIVE: To describe a modified technique for permanent translocation of the common carotid artery (CCA) to a subcutaneous position in standing horses. STUDY DESIGN: Experimental study. ANIMALS: Healthy adult Standardbred and Warmblood horses (n = 8). METHODS: Surgery was performed with the horses standing under sedation and with local anesthesia. A combination of previously described techniques was used modifying the approach and closure of the incision...
November 28, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27891376/smokeless-tobacco-and-stroke-a-clinico-epidemiological-follow-up-study-in-a-tertiary-care-hospital
#6
Subhransu Sekhar Jena, Shobhitendu Kabi, Baikuntha Nath Panda, B C Kameswari, Payal, Ishwar Chandra Behera, Subrat Kumar Tripathy, Seemanchana Mahanta
INTRODUCTION: Among the modifiable risk factors for stroke, tobacco smoking is well recognized. In some studies the use of Smokeless Tobacco (ST) has also been contributed as a risk factor for ischemic stroke. Use of ST is very common in South-East Asia. The form of ST varies according to the geographical and cultural variation. AIM: To study the various clinical symptoms and radiological findings of stroke due to different types of ST. MATERIALS AND METHODS: This was a prospective hospital based study carried out over a period of 2 years...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27882910/does-nintendo-wii-balance-board-improve-standing-balance-a-randomised-controlled-trial-in-children-with-cerebral-palsy
#7
Valeska Gatica-Rojas, Guillermo Méndez-Rebolledo, Eduardo Guzman-Muñoz, Alex Soto-Poblete, Ricardo Cartes-Velásquez, Edith Elgueta-Cancino, Eduardo Cofré Lizama
BACKGROUND: Evidence on the effect of systemic exercise programs to improve the standing balance with the Nintendo Wii system is very limited and its post- treatment effectiveness is unknown in cerebral palsy (CP) patients. AIM: Primary aim was to compare the effect of Nintendo Wii balance board (Wii- therapy) and standard physiotherapy (SPT), on the performance of standing balance in children and adolescents with CP. Secondary aim was to determine the post-treatment effectiveness of Wii-therapy and SPT...
November 24, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27882256/eeg-triggered-functional-electrical-stimulation-therapy-for-restoring-upper-limb-function-in-chronic-stroke-with-severe-hemiplegia
#8
Cesar Marquez-Chin, Aaron Marquis, Milos R Popovic
We report the therapeutic effects of integrating brain-computer interfacing technology and functional electrical stimulation therapy to restore upper limb reaching movements in a 64-year-old man with severe left hemiplegia following a hemorrhagic stroke he sustained six years prior to this study. He completed 40 90-minute sessions of functional electrical stimulation therapy using a custom-made neuroprosthesis that facilitated 5 different reaching movements. During each session, the participant attempted to reach with his paralyzed arm repeatedly...
2016: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/27879456/hindlimb-spasticity-after-unilateral-motor-cortex-lesion-in-rats-is-reduced-by-contralateral-nerve-root-transfer
#9
Hai Yang Zong, Fenfen Ma, Lai Yin Zhang, Hui Ping Lu, Jing Ru Gong, Min Cai, Hao Dong Lin, Yizhun Zhun Zhu, Chun Lin Hou
The aim was to test the feasibility and effectiveness of contralateral nerve root transfer in reducing post stroke spasticity of the affected hindlimb muscles in rats. In our study, we for the first time created a novel animal hindlimb spastic hemiplegia model in rats with photothrombotic lesion of unilateral motor cortex and we established a novel surgical procedure in reducing motor cortex lesion induced hindlimb spastic hemiplegia in rats. Thirty six rats were randomized into three groups. In group A, rats received sham operation...
November 22, 2016: Bioscience Reports
https://www.readbyqxmd.com/read/27866949/perioperative-periprosthetic-fractures-associated-with-primary-total-hip-arthroplasty
#10
Kwan J Park, Mariano E Menendez, C Lowry Barnes
BACKGROUND: Periprosthetic fracture (PPF) is a rare but devastating complication of primary total hip arthroplasty (THA). While PPF is associated with increased morbidity and mortality, early revision rate, and poor patient outcome, there is a paucity of data on patient and hospital-dependent risk factors. Using a large administrative database, we investigated epidemiology and the risk factors associated with perioperative PPF after primary THA. METHODS: We performed a retrospective review of the National Inpatient Sample records from 2006 to 2011 and identified 1062 PPFs of 1,187,969 patients using International Classification of Diseases, Ninth Revision code for PPF (996...
August 31, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27858578/severe-cerebral-edema-following-nivolumab-treatment-for-pediatric-glioblastoma-case-report
#11
Xiao Zhu, Michael M McDowell, William C Newman, Gary E Mason, Stephanie Greene, Mandeep S Tamber
Nivolumab is an immune checkpoint inhibitor (ICI) currently undergoing Phase III clinical trials for the treatment of glioblastoma. The authors present the case of a 10-year-old girl with glioblastoma treated with nivolumab under compassionate-use guidelines. After the first dose of nivolumab the patient developed hemiparesis, cerebral edema, and significant midline shift due to severe tumor necrosis. She was managed using intravenous dexamethasone and discharged on a dexamethasone taper. The patient's condition rapidly deteriorated after the second dose of nivolumab, demonstrating hemiplegia, seizures, and eventually unresponsiveness with a fixed and dilated left pupil...
November 18, 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27857035/recovery-of-long-term-paresis-following-resection-of-who-grade-ii-gliomas-infiltrating-the-pyramidal-pathway
#12
Juan Martino, Hugo Caballero, Enrique M DE Lucas, Rousinelle DA Silva-Freitas, Carlos Velasquez, Elsa Gomez, Javier Vazquez-Bourgon, Alfonso Vázquez-Barquero
Recent publications had reported high rates of preoperative neurological impairments in WHO grade II gliomas (GIIG) that significantly affect the quality of life. Consequently, one step further in the analysis of surgical outcome in GIIG is to evaluate if surgery is capable to improve preoperative deficits. Here are reported two cases of GIIG infiltrating the primary motor cortex and pyramidal pathway that had a long-term paresis before surgery. Both patients were operated with intraoperative electrical stimulation mapping, with identification and preservation of the primary motor cortex and pyramidal tract...
February 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27852706/efficacy-of-two-injection-site-localisation-techniques-for-botulinum-toxin-injections-a-single-blind-crossover-randomised-trial-protocol-among-adults-with-hemiplegia-due-to-stroke
#13
Claire Morel, Isabelle Hauret, Nicolas Andant, Armand Bonnin, Bruno Pereira, Emmanuel Coudeyre
INTRODUCTION: Botulinum toxin injections are an effective treatment for limb spasticity following stroke. Different tracking techniques are used for this purpose: palpation, electrostimulation, electromyography and ultrasound. Yet very few studies have compared these different techniques, and none has successfully proved the superior efficacy of ultrasound-guided injections compared to another tracking method. The primary objective of our study was therefore to compare the efficacy of botulinum toxin injections depending on the tracking technique used: ultrasound versus electrostimulation...
November 15, 2016: BMJ Open
https://www.readbyqxmd.com/read/27833886/a-drastic-aftermath-of-embolisation-in-juvenile-nasopharyngeal-angiofibroma
#14
Narayanan Janakiram, Shilpee Bhatia Sharma, Vidya Bhargavan Panicker, C V Srinivas
The role of preoperative embolization in alleviating intra operative haemorrhage in small to medium sized JNA is dubious. We report an unusual case of JNA who developed cerebral edema, hemiplegia and aphasia following glue embolisation and underwent frontotemporal craniectomy. This drastic aftermath of embolisation challenges the safety of preoperative embolisation in such lesions.
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27830942/postural-asymmetry-correlated-with-lateralization-of-cerebellar-perfusion-in-persons-with-chronic-stroke-a-role-of-crossed-cerebellar-diaschisis-in-left-side
#15
Cheng-Chiang Chang, Chih-Hung Ku, Shin-Tsu Chang
OBJECTIVE: Hemiplegia after stroke leads to impairment of the affected limbs and induces more weight on the non-paretic lower limb to form postural asymmetry. Studies of asymmetric cerebral functions have found similarly asymmetric functions in the cerebellum. Crossed cerebellar diaschisis (CCD) is defined as reduced blood flow and hypometabolism in the cerebellar hemisphere contralateral to supratentorial cerebral pathology. No study explored the relationship between posture (standing balance) and CCD in those persons yet...
November 10, 2016: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27829722/cerebral-hyperperfusion-syndrome-after-intracranial-stenting-of-the-middle-cerebral-artery
#16
Boby Varkey Maramattom
Cerebral hyperperfusion syndrome (CHS) is a rare complication following cerebral revascularization. It presents with ipsilateral headache, seizures, and intracerebral hemorrhage. It has mostly been described following extracranial carotid endarterectomy and stenting and it is very unusual after intracranial stenting. A 71-year-old man with a stuttering stroke was taken up for a cerebral angiogram (digital subtraction angiography), which showed a dissection of the distal left middle cerebral artery. This was recanalized with a solitaire AB stent...
October 2016: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/27829642/reversible-motor-paralysis-and-early-cardiac-rehabilitation-in-patients-with-advanced-heart-failure-receiving-left-ventricular-assist-device-therapy
#17
Rie Amao, Teruhiko Imamura, Yasuo Nakahara, Satoko Noguchi, Osamu Kinoshita, Haruo Yamauchi, Minoru Ono, Nobuhiko Haga
Advanced heart failure (HF) is sometimes complicated with brain impairment because of a microthrombosis caused by decreased left ventricular contraction or reduced brain circulation. Some patients may recover after left ventricular assist device (LVAD) implantation. However, little is known about the perioperative therapeutic strategy in patients suffering from such complications, particularly from a cardiac rehabilitation viewpoint. We report on a 58-year-old male patient with a previous history of poliomyelitis and a light paralysis in the left upper extremity, who suffered left hemiplegia with no evidence of stroke after hemodynamic deterioration...
November 9, 2016: International Heart Journal
https://www.readbyqxmd.com/read/27829640/experiences-with-aggressive-cardiac-rehabilitation-in-pediatric-patients-receiving-mechanical-circulatory-supports
#18
Rie Amao, Teruhiko Imamura, Yusuke Sawada, Sachiko Endo, Shinichi Ozaki, Kenichi Okamura, Akihiro Masuzawa, Tetsuhiro Takaoka, Yasutaka Hirata, Takahiro Shindo, Minoru Ono, Nobuhiko Haga
Although some patients with fulminant myocarditis can be rescued owing to the improvements in mechanical circulatory support therapy, there are few reports providing evidence of cardiac rehabilitation during mechanical circulatory supports, particularly among pediatric patients. We treated two pediatric patients who underwent aggressive cardiac rehabilitation during mechanical support. Five days after the initiation of extracorporeal membrane oxygenation therapy aggressive cardiac rehabilitation was started in a 10-year-old girl with fulminant myocarditis...
November 9, 2016: International Heart Journal
https://www.readbyqxmd.com/read/27829533/dermatomal-sensory-manifestations-in-opalski-syndrome
#19
Tomoya Kon, Yukihisa Funamizu, Tatsuya Ueno, Rie Haga, Haruo Nishijima, Akira Arai, Chieko Suzuki, Jinichi Nunomura, Masayuki Baba, Masahiko Tomiyama
A 31-year-old Japanese woman presented with sudden-onset unstable gait followed by nuchal pain. A neurological examination revealed right-sided limb weakness and decreased pain and thermal sensation on the left side below the level of the L1 dermatome. A lower lateral medullary infarction with ipsilateral hemiplegia, known as Opalski syndrome, caused by spontaneous vertebral artery dissection was diagnosed by magnetic resonance imaging. The spinothalamic tract in the medulla oblongata has a topographic arrangement of sensory fibers, and the dermatomal sensory deficit in this case can be explained in relation to that...
November 7, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27828736/an-unusual-cause-of-hemiplegia-post-percutaneous-coronary-intervention
#20
Caroline J Magri, Dillon Mintoff, Sara Xuereb, Robert G Xuereb
No abstract text is available yet for this article.
November 2, 2016: British Journal of Hospital Medicine
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