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Breast cancer, MRI

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https://www.readbyqxmd.com/read/28221238/additional-magnetic-resonance-imaging-detected-suspicious-lesions-in-known-patients-with-breast-cancer-comparison-of-second-look-digital-tomosynthesis-and-ultrasonography
#1
Jieun Koh, Eun-Kyung Kim, Min Jung Kim, Jung Hyun Yoon, Hee Jung Moon
PURPOSE: The aim of the study was to compare the performances of second-look digital breast tomosynthesis (DBT) and ultrasonography (US) for additional magnetic resonance imaging (MRI)-detected suspicious lesions in patients referred for breast cancer. METHODS: Fifty-five patients (52.5 [9.3] years) with breast cancers newly diagnosed at a referring hospital underwent MRI and afterward DBT and US in our institution. The frequency for detecting additional MRI-detected suspicious lesions on DBT and US and performances of DBT and US were compared...
February 18, 2017: Ultrasound Quarterly
https://www.readbyqxmd.com/read/28220929/increasing-the-efficiency-on-producing-radiology-reports-for-breast-cancer-diagnosis-by-means-of-structured-reports-a-comparative-study
#2
J Damian Segrelles, Rosana Medina, Ignacio Blanquer, Luis Martí-Bonmatí
BACKGROUND: Radiology reports are commonly written on free-text using voice recognition devices. Structured reports (SR) have a high potential but they are usually considered more difficult to fill-in so their adoption in clinical practice leads to a lower efficiency. However, some studies have demonstrated that in some cases, producing SRs may require shorter time than plain-text ones. This work focuses on the definition and demonstration of a methodology to evaluate the productivity of software tools for producing radiology reports...
February 21, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28219911/triple-negative-breast-cancer-with-brain-metastasis-in-a-pregnant-woman
#3
Francisco Trinca, Mariana Inácio, Teresa Timóteo, Rui Dinis
A woman aged 35 years was diagnosed with triple-negative breast cancer in October 2012. During the investigation, it was discovered that she was pregnant, the patient decided to have an abortion. She was submitted to a radical modified mastectomy and adjuvant chemotherapy followed by adjuvant breast radiotherapy of the left breast. 2 months after the adjuvant treatment, she began to have headaches and dizziness. The cranial MRI (head MRI) showed brain metastasis. She was then treated with whole brain radiotherapy, stereotactic radiosurgery and concomitant temozolomide which resulted in complete response...
February 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28218347/breast-cancer-early-diagnosis-and-effective-treatment-by-drug-delivery-tracing
#4
Mahdiyeh Shamsi, Jalil Pirayesh Islamian
Breast cancer is the most frequent cancer in women and it is the main reason of cancer-related deaths of women worldwide. Different types of breast cancer diagnostic examinations are also available, such as mammography, MRI, biopsy, ultrasound and molecular imaging. Radionuclide-based imaging methods including SPECT and PET are useful in early diagnosis and treatment of the cancer. The radiolabeling of chemo drugs with nanoparticles should be recommended from the standpoint of an early diagnosis and effective treatment of breast cancer...
2017: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/28210553/impact-of-value-based-breast-cancer-care-pathway-implementation-on-pre-operative-breast-magnetic-resonance-imaging-utilization
#5
Devina K S McCray, Stephen R Grobmyer, Holly J Pederson
BACKGROUND: Bilateral breast magnetic resonance imaging (MRI) is commonly used in the diagnostic workup of breast cancer (BC) to assess extent of disease and identify occult foci of disease. However, evidence for routine use of pre-operative MRI is lacking. Breast MRI is costly and can lead to unnecessary tests and treatment delays. Clinical care pathways (care paths) are value-based guidelines, which define management recommendations derived by expert consensus and available evidence based data...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28209330/role-of-magnetic-resonance-imaging-in-detection-of-pathologic-complete-remission-in-breast-cancer-patients-treated-with-neoadjuvant-chemotherapy-a-meta-analysis
#6
REVIEW
Yan-Lin Gu, Si-Meng Pan, Jie Ren, Zhi-Xue Yang, Guo-Qin Jiang
Pathologic complete remission after neoadjuvant chemotherapy has a role in guiding the management of breast cancer. The present meta-analysis examined the accuracy of contrast-enhanced magnetic resonance imaging (CE-MRI) and diffusion-weighted magnetic resonance imaging (DW-MRI) in detecting the response to neoadjuvant chemotherapy and compared CE-MRI with ultrasonography, mammography, and positron emission tomography/computed tomography (PET/CT). Medical subject heading terms and related keywords were searched to generate a compilation of eligible studies...
January 11, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28203064/women-s-experiences-and-preferences-regarding-breast-imaging-after-completing-breast-cancer-treatment
#7
Susan Brandzel, Dori E Rosenberg, Dianne Johnson, Mary Bush, Karla Kerlikowske, Tracy Onega, Louise Henderson, Larissa Nekhlyudov, Wendy DeMartini, Karen J Wernli
BACKGROUND: After treatment for breast cancer, most women receive an annual surveillance mammography to look for subsequent breast cancers. Supplemental breast MRI is sometimes used in addition to mammography despite the lack of clinical evidence for it. Breast imaging after cancer treatment is an emotionally charged experience, an important part of survivorship care, and a topic about which limited patient information exists. We assessed women's experiences and preferences about breast cancer surveillance imaging with the goal of determining where gaps in care and knowledge could be filled...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28187928/2-d-and-3-d-ultrasound-for-tumor-volume-analysis-a%C3%A2-prospective%C3%A2-study
#8
Segundo J González, Blaise Mooney, Hui-Yi Lin, Xiuhua Zhao, John V Kiluk, Nazanin Khakpour, Christine Laronga, M Catherine Lee
Ultrasound (US) allows real-time tumor assessment. We evaluated the volumetric limits of 2-D and 3-D US, compared with magnetic resonance imaging (MRI), with a prospective institutional review board-approved clinical evaluation of US-to-MRI volumetric correlation. US images of pre- and post-neoadjuvant breast cancers were obtained. Volume discrepancy was evaluated with the non-parametric Wilcoxon signed-rank test. Expected inter-observer variability <14% was evaluated as relative paired difference (RPD); clinical relevance was gauged with the volumetric standard error of the mean (SEM)...
February 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28187373/impact-of-selective-use-of-breast-mri-on-surgical-decision-making-in-women-with-newly-diagnosed-operable-breast-cancer
#9
Meagan E Brennan, Merran McKessar, Kylie Snook, Ian Burgess, Andrew J Spillane
BACKGROUND: This study evaluated the impact of breast MRI on surgical planning in selected cases of breast malignancy (invasive cancer or DCIS). MRI was used when there was ambiguity on clinical and/or conventional imaging assessment. METHODS: Consecutive women with breast malignancy undergoing breast MRI were included. Clinical, mammogram and ultrasound findings and surgical plan before and after MRI were recorded. MRI findings and histopathology results were documented and the impact of MRI on treatment planning was evaluated...
February 7, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28184053/gastrointestinal-diseases-and-their-oro-dental-manifestations-part-4-peutz-jeghers-syndrome
#10
S E Korsse, M E van Leerdam, E Dekker
Peutz-Jeghers syndrome (PJS) is a rare, autosomal dominant inherited disorder, caused by germline mutations in the LKB1 tumour suppressor gene. It is clinically characterised by distinct perioral mucocutaneous pigmentations, gastrointestinal polyposis and an increased cancer risk in adult life. Hamartomatous polyps can develop already in the first decade of life and may cause various complications, including abdominal pain, bleeding, anaemia, and acute intestinal obstruction. Furthermore, patients have an increased risk for developing cancer, both in the gastrointestinal tract as in other organs...
February 10, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28181348/can-algorithmically-assessed-mri-features-predict-which-patients-with-a-preoperative-diagnosis-of-ductal-carcinoma-in-situ-are-upstaged-to-invasive-breast-cancer
#11
Michael R Harowicz, Ashirbani Saha, Lars J Grimm, P Kelly Marcom, Jeffrey R Marks, E Shelley Hwang, Maciej A Mazurowski
PURPOSE: To assess the ability of algorithmically assessed magnetic resonance imaging (MRI) features to predict the likelihood of upstaging to invasive cancer in newly diagnosed ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: We identified 131 patients at our institution from 2000-2014 with a core needle biopsy-confirmed diagnosis of pure DCIS, a 1.5 or 3T preoperative bilateral breast MRI with nonfat-saturated T1 -weighted MRI sequences, no preoperative therapy before breast MRI, and no prior history of breast cancer...
February 9, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28177554/identifying-relations-between-imaging-phenotypes-and-molecular-subtypes-of-breast-cancer-model-discovery-and-external-validation
#12
Jia Wu, Xiaoli Sun, Jeff Wang, Yi Cui, Fumi Kato, Hiroki Shirato, Debra M Ikeda, Ruijiang Li
PURPOSE: To determine whether dynamic contrast enhancement magnetic resonance imaging (DCE-MRI) characteristics of the breast tumor and background parenchyma can distinguish molecular subtypes (ie, luminal A/B or basal) of breast cancer. MATERIALS AND METHODS: In all, 84 patients from one institution and 126 patients from The Cancer Genome Atlas (TCGA) were used for discovery and external validation, respectively. Thirty-five quantitative image features were extracted from DCE-MRI (1...
February 8, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28176853/quantifying-tumor-associated-macrophages-in-breast-cancer-a-comparison-of-iron-and-fluorine-based-mri-cell-tracking
#13
Ashley V Makela, Jeffrey M Gaudet, Paula J Foster
Tumor associated macrophages (TAMs) are associated with tumor growth and metastasis. MRI can detect TAMs labeled with iron oxide (USPIO) or perfluorocarbon (PFC) agents. This study compared these two cell tracking approaches for imaging TAMs in vivo. 4T1 tumors were imaged with MRI at 4 days or 3 weeks post cell implantation after intravenous (i.v.) administration of either USPIO or PFC. Signal loss was detected within tumors at both time points post USPIO. Images acquired at 4 days demonstrated signal loss encompassing the entire tumor and around the periphery at 3 weeks...
February 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28170371/imaging-tests-in-staging-and-surveillance-of-non-metastatic-breast-cancer-changes-in-routine-clinical-practice-and-cost-implications
#14
S De Placido, C De Angelis, M Giuliano, C Pizzi, R Ruocco, V Perrone, D Bruzzese, G Tommasielli, M De Laurentiis, S Cammarota, G Arpino, G Arpino
BACKGROUND: Although guidelines do not recommend computerised tomography (CT), positron emission tomography (PET) or magnetic resonance imaging (MRI) for the staging or follow-up of asymptomatic patients with non-metastatic breast cancer, they are often requested in routine clinical practice. The aim of this study was to determine the staging and follow-up patterns, and relative costs in a large population of breast cancer patients living and treated in a Southern Italian region. METHODS: We analysed the clinical computerised information recorded by 567 primary-care physicians assisting about 650 000 inhabitants in the Campania region...
February 7, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28169313/visualization-of-tumor-related-blood-vessels-in-human-breast-by-photoacoustic-imaging-system-with-a-hemispherical-detector-array
#15
M Toi, Y Asao, Y Matsumoto, H Sekiguchi, A Yoshikawa, M Takada, M Kataoka, T Endo, N Kawaguchi-Sakita, M Kawashima, E Fakhrejahani, S Kanao, I Yamaga, Y Nakayama, M Tokiwa, M Torii, T Yagi, T Sakurai, K Togashi, T Shiina
Noninvasive measurement of the distribution and oxygenation state of hemoglobin (Hb) inside the tissue is strongly required to analyze the tumor-associated vasculatures. We developed a photoacoustic imaging (PAI) system with a hemispherical-shaped detector array (HDA). Here, we show that PAI system with HDA revealed finer vasculature, more detailed blood-vessel branching structures, and more detailed morphological vessel characteristics compared with MRI by the use of breast shape deformation of MRI to PAI and their fused image...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28166261/radiomic-analysis-reveals-dce-mri-features-for-prediction-of-molecular-subtypes-of-breast-cancer
#16
Ming Fan, Hui Li, Shijian Wang, Bin Zheng, Juan Zhang, Lihua Li
The purpose of this study was to investigate the role of features derived from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and to incorporated clinical information to predict the molecular subtypes of breast cancer. In particular, 60 breast cancers with the following four molecular subtypes were analyzed: luminal A, luminal B, human epidermal growth factor receptor-2 (HER2)-over-expressing and basal-like. The breast region was segmented and the suspicious tumor was depicted on sequentially scanned MR images from each case...
2017: PloS One
https://www.readbyqxmd.com/read/28166153/cerebral-parenchymal-photopenia-on-fdg-pet-ct-reflecting-vasogenic-edema-due-to-leptomeningeal-metastasis-in-breast-cancer
#17
Mitsutomi Ishiyama, Manuela Christina Matesan
A 61-year-old woman with metastatic breast cancer presented with migrainelike episodes over the past 10 months. FDG-PET/CT(PET/CT) showed relatively symmetric areas of photopenia predominantly in the bilateral superior parietal lobules. Subsequent contrast-enhanced MRI revealed leptomeningeal metastasis in the bilateral posterior parietal regions with associated vasogenic edema in the adjacent brain parenchyma. There was no clear evidence of parenchymal metastasis on MRI. After chemotherapy, the areas of abnormality resolved on PET/CT 8 months later, and the patient showed interval symptomatic improvement...
February 3, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28157381/informing-women-and-their-physicians-about-recommendations-for-adjunct-breast-mri-screening-a-cohort-study
#18
John T Brinton, Lora D Barke, Mary E Freivogel, Tiffany C Talley, Michelle D Lexin, Alicia L Drew, Rachel B Beam, Deborah H Glueck
It is unclear how best to communicate recommendations for breast cancer screening with MRI as an adjunct to mammography for women at high risk. This study compares the rates of breast MRI screening for two different methods of communication. The retrospective IRB-approved cohort study was conducted at Invision Sally Jobe Breast Centers (ISJBC). ISJBC provided Gail model risk assessment to all women presenting for screening mammography. Women with scores ≥ 19.6% were considered to be high risk. Over 2 years, ISJBC used two different methods to inform women at elevated lifetime risk and their physicians about recommendations for adjunct MRI screening (N = 561, mean age = 52 years, s...
February 3, 2017: Health Communication
https://www.readbyqxmd.com/read/28152879/contralateral-prophylactic-mastectomy-decision-making-in-the-population-based-icancare-study-of-early-stage-breast-cancer-patients
#19
Sarah T Hawley, Kent A Griffith, Nancy K Janz, Allison W Kurian, Kevin C Ward, Ann S Hamilton, Steven J Katz, Monica Morrow
: 177 Background: Contralateral prophylactic mastectomy (CPM) use is increasing in women who are not at increased risk of contralateral cancer development and will experience no survival benefit from the more morbid procedure. Little is known about treatment decision-making or provider interactions. METHODS: We surveyed a weighted random sample of newly diagnosed patients with early-stage breast cancer who were treated in 2013-14, identified through the population-based SEER registries of Los Angeles and Georgia about 3 months after surgical treatment, and merged with SEER data (N=2632, RR=70%), to determine receipt of diagnostic tests and factors related to the decision about surgery (including knowledge and perceived physician recommendation)...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152694/using-a-disease-pathway-management-approach-to-improve-the-quality-of-breast-cancer-care-in-ontario
#20
Jasmin Soobrian, Ashley Tyrrell, Clement Li, Derek Muradali, Margaret F Forbes, Angelika Gollnow, Jillian Ross, Claire Holloway
: 109 Background: Disease Pathway Management (DPM) is used by Cancer Care Ontario (CCO) to set priorities for cancer control, plan cancer services, and improve the quality of care in Ontario by promoting standardization. The DPM approach applies a framework to examine the performance of the entire system from prevention to end of life care, and to identify any gaps within the system. In 2014, DPM began its breast cancer pathway initiative by mapping the patient journey, depicting evidence-based best practice along the breast cancer care continuum, identifying where further guidance is needed for clinical decision making, and identifying gaps in quality of care and performance measurement indicators...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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