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https://www.readbyqxmd.com/read/28079829/breath-hold-and-free-breathing-f-18-fdg-pet-ct-in-malignant-melanoma-detection-of-additional-tumoral-foci-and-effects-on-quantitative-parameters
#1
Robert Bärwolf, Mariana Zirnsak, Martin Freesmeyer
During PET/CT acquisition, respiratory motion generates artifacts in the form of breath-related blurring, which may impair lesion detectability and diagnostic accuracy. This observational study was undertaken to verify whether breath-hold F-18-FDG-PET/CT (bhPET) detects additional foci compared to free-breathing PET/CT (fbPET) in cases of malignant melanoma, and to assess the impact of breath-holding on standard uptake values (SUV) and metabolic isocontoured volume (mVic40).Thirty-four patients with melanoma were examined...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28079825/the-utility-of-bispectral-index-monitoring-for-prevention-of-rocuronium-induced-withdrawal-movement-in-children-a-randomized-controlled-trial
#2
Byung Gun Lim, Il Ok Lee, Young Sung Kim, Young Ju Won, Heezoo Kim, Myoung Hoon Kong
BACKGROUND: This study was designed to determine whether a deep hypnotic state with a bispectral index (BIS) value less than 40 could alleviate withdrawal movement (WM) upon rocuronium injection during anesthesia induction in children. METHODS: Finally, 135 healthy children (3-12 years) scheduled for minor elective surgery were studied. Without premedication, anesthesia was induced with thiopental sodium 5 mg/kg. Patients were randomized into 2 groups (control vs experimental) and then by virtue of rocuronium injection time, patients in the experimental group were allocated into 2 groups, as follows: in the control group (group C; n = 45), rocuronium 0...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28079815/morning-breathing-exercises-prolong-lifespan-by-improving-hyperventilation-in-people-living-with-respiratory-cancer
#3
Wei-Jie Wu, Shan-Huan Wang, Wei Ling, Li-Jun Geng, Xiao-Xi Zhang, Lan Yu, Jun Chen, Jiang-Xi Luo, Hai-Lu Zhao
Disturbance of oxygen-carbon dioxide homeostasis has an impact on cancer. Little is known about the effect of breath training on cancer patients. Here we report our 10-year experience with morning breathing exercises (MBE) in peer-support programs for cancer survivors.We performed a cohort study to investigate long-term surviving patients with lung cancer (LC) and nasopharyngeal cancer (NPC) who practiced MBE on a daily basis. End-tidal breath holding time (ETBHT) after MBE was measured to reflect improvement in alveolar O2 pressure and alveolar CO2 pressure capacity...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28071964/hypercapnia-is-essential-to-reduce-the-cerebral-oxidative-metabolism-during-extreme-apnea-in-humans
#4
Anthony R Bain, Philip N Ainslie, Otto F Barak, Ryan L Hoiland, Ivan Drvis, Tanja Mijacika, Damian M Bailey, Antoinette Santoro, Daniel K DeMasi, Zeljko Dujic, David B MacLeod
The cerebral metabolic rate of oxygen (CMRO2) is reduced during apnea that yields profound hypoxia and hypercapnia. In this study, to dissociate the impact of hypoxia and hypercapnia on the reduction in CMRO2, 11 breath-hold competitors completed three apneas under: (a) normal conditions (NM), yielding severe hypercapnia and hypoxemia, (b) with prior hyperventilation (HV), yielding severe hypoxemia only, and (c) with prior 100% oxygen breathing (HX), yielding the greatest level of hypercapnia, but in the absence of hypoxemia...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28065694/real-time-cardiac-magnetic-resonance-cine-imaging-with-sparse-sampling-and-iterative-reconstruction-for-left-ventricular-measures-comparison-with-gold-standard-segmented-steady-state-free-precession
#5
Gabriel C Camargo, Fernanda Erthal, Leticia Sabioni, Filipe Penna, Ralph Strecker, Michaela Schmidt, Michael O Zenge, Ronaldo de S L Lima, Ilan Gottlieb
BACKGROUND: Segmented cine imaging with a steady-state free-precession sequence (Cine-SSFP) is currently the gold standard technique for measuring ventricular volumes and mass, but due to multi breath-hold (BH) requirements, it is prone to misalignment of consecutive slices, time consuming and dependent on respiratory capacity. Real-time cine avoids those limitations, but poor spatial and temporal resolution of conventional sequences has prevented its routine application. We sought to examine the accuracy and feasibility of a newly developed real-time sequence with aggressive under-sampling of k-space using sparse sampling and iterative reconstruction (Cine-RT)...
January 5, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28065661/generalism-in-modern-subspecializing-medicine
#6
Marcel Levi
INTRODUCTION: Medicine is currently developing at a breath holding pace. Diseases and medical conditions for which no remedy was available only a few years ago, can now be treated or even completely cured. However, this advancement of medicine comes with increasing complexity in many situations. AIM AND METHOD: This article discusses how we have to adapt our health care organization and our work as physicians to better cope with the new challenges of the enormous advancement of medicine, with a specific focus on internal medicine...
January 5, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28058956/neuromuscular-blockade-and-inspiratory-breath-hold-during-stereotactic-body-radiation-therapy-for-treatment-of-heart-base-tumors-in-four-dogs
#7
Krista L Kelsey, Lyndsay N Kubicek, Nicholas J Bacon, Terry Torres, Sheilah A Robertson
CASE DESCRIPTION 4 dogs were examined because of pleural effusion and ventricular tachycardia, coughing and supraventricular tachycardia, appendicular osteosarcoma, and syncopal episodes. CLINICAL FINDINGS In all 4 dogs, a heart base tumor was identified by means of thoracic CT. TREATMENT AND OUTCOME In all 4 dogs, the heart base tumors were treated by means of stereotactic body radiation therapy. Dogs were anesthetized, and neuromuscular blockade was achieved with atracurium or vecuronium. A circle rebreathing system with 15 m (50 feet) of anesthetic tubing coursing through the vault wall was used to connect the patient to the anesthesia machine, which was located in the control room...
January 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28051962/drowning-deaths-from-unsupervised-breath-holding-separating-necessary-training-from-unwarranted-risk
#8
Jordan D Lane
No abstract text is available yet for this article.
January 2017: Military Medicine
https://www.readbyqxmd.com/read/28048853/su-f-p-14-oxygen-inhalation-should-be-the-conventional-approach-in-the-treatment-of-thoracic-and-abdominal-cancer-by-radiotherapy-with-active-breathing-control-abc
#9
G Gong, Y Guo, Y Yin
PURPOSE: To investigate the feasibility and potential benefit of oxygen inhalation (OI) during radiotherapy applying an active breathing control (ABC) device, by analyzing the blood oxygen saturation (SpO2) and the instantaneous heart rate (IHR) variation in breath holding with OI and oxygen non-inhalation (ONI). METHODS: The 27 healthy volunteers (16 males, 11 females) who were involved in this trial were all required to hold their breath for 10 times, non-inhaling and inhaling oxygen successively...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048848/mo-fg-campus-jep3-04-feasibility-study-of-real-time-ultrasound-monitoring-for-abdominal-stereotactic-body-radiation-therapy
#10
Lin Su, Sook Kien Ng, Ying Zhang, Tianlong Ji, Iulian Iordachita, Joseph Herman, John Wong, H Tutkun Sen, Peter Kazanzides, Muyinatu A Lediju Bell, Kai Ding
PURPOSE: Ultrasound is ideal for real-time monitoring in radiotherapy with high soft tissue contrast, non-ionization, portability, and cost effectiveness. Few studies investigated clinical application of real-time ultrasound monitoring for abdominal stereotactic body radiation therapy (SBRT). This study aims to demonstrate the feasibility of real-time monitoring of 3D target motion using 4D ultrasound. METHODS: An ultrasound probe holding system was designed to allow clinician to freely move and lock ultrasound probe...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048836/su-f-j-30-application-of-intra-fractional-imaging-for-pretreatment-cbct-of-breath-hold-lung-sbrt
#11
D Cao, M Jermoumi, V Mehta, D Shepard
PURPOSE: Clinical implementation of gated lung SBRT requires tools to verify the accuracy of the target positioning on a daily basis. This is a particular challenge on Elekta linacs where the XVI imaging system does not interface directly to any commercial gating solution. In this study, we used the Elekta's intra-fractional imaging functionality to perform the pretreatment CBCT verifications and evaluated both the image quality and gating accuracy. METHODS: To use intrafraction imaging tools for pretreatment verifications, we planned a 360-degree arc with 1mmx5mm MLC opening...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048831/su-g-jep4-01-an-assessment-of-a-microsoft-kinect-v2-sensor-for-voluntary-breath-hold-monitoring-in-radiotherapy
#12
D Edmunds, E Donovan
PURPOSE: To determine whether the Microsoft Kinect Version 2 (Kinect v2), a commercial off-the-shelf (COTS) depth sensors designed for entertainment purposes, were robust to the radiotherapy treatment environment and could be suitable for monitoring of voluntary breath-hold compliance. This could complement current visual monitoring techniques, and be useful for heart sparing left breast radiotherapy. METHODS: In-house software to control Kinect v2 sensors, and capture output information, was developed using the free Microsoft software development kit, and the Cinder creative coding C++ library...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048824/su-f-t-123-the-simulated-effect-of-the-breath-hold-reproducibility-treating-locally-advanced-lung-cancer-with-pencil-beam-scanned-proton-therapy
#13
J Dueck, R Perrin, G F Persson, A Lomax, M Josipovic, S A Engelholm, D C Weber, P Munck, A F Rosenschöld
PURPOSE: The breath-hold (BH) technique has been suggested to mitigate motion and reduce target coverage degradation due to motion effects. The aim of this study was to investigate the effect of inter-BH residual motion on the dose distribution for pencil beam scanned (PBS) proton therapy of locally-advanced lung cancer patients. METHODS: A dataset of visually-guided BH CT scans was acquired (10 scans per patient) taken from five lung cancer patients: three intra-fractionally repeated CT scans on treatment days 2,16 and 31, in addition to the day 0 planning CT scan...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048814/su-f-j-123-ct-based-determination-of-dibh-variability-and-its-dosimetric-impact-on-post-mastectomy-plus-regional-nodal-radiation-therapy
#14
M Malin, H Kang, K Tatebe, Y Hasan, S Chmura, H Al-Hallaq
PURPOSE: Breast cancer radiotherapy delivered using voluntary deep inspiration breath-hold (DIBH) requires reproducible breath holds, particularly when matching supraclavicular fields to tangential fields. We studied the impact of variation in DIBHs on CTV and OAR dose metrics by comparing the dose distribution computed on two DIBH CT scans taken at the time of simulation. METHODS: Ten patients receiving 50Gy in 25 fractions to the left chestwall and regional lymph nodes were studied...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048808/su-f-j-19-robust-region-of-interest-roi-for-consistent-registration-on-deteriorated-surface-images
#15
H Kang, M Malin, S Chmura, Y Hasan, H Al-Hallaq
PURPOSE: For African-American patients receiving breast radiotherapy with a bolus, skin darkening can affect the surface visualization when using optical imaging for daily positioning and gating at deep-inspiration breath holds (DIBH). Our goal is to identify a region-of-interest (ROI) that is robust against deteriorating surface image quality due to skin darkening. METHODS: We study four patients whose post-mastectomy surfaces are imaged daily with AlignRT (VisionRT, UK) for DIBH radiotherapy and whose surface image quality is degraded toward the end of treatment...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048736/su-f-j-55-feasibility-of-supraclavicular-field-treatment-by-investigating-variation-of-junction-position-between-breast-tangential-and-supraclavicular-fields-for-deep-inspiration-breath-hold-dibh-left-breast-radiation
#16
H Zhao, V Sarkar, A Paxton, P Rassiah-Szegedi, Y Huang, M Szegedi, L Huang, F Su, B Salter
PURPOSE: To explore the feasibility of supraclavicular field treatment by investigating the variation of junction position between tangential and supraclavicular fields during left breast radiation using DIBH technique. METHODS: Six patients with left breast cancer treated using DIBH technique were included in this study. AlignRT system was used to track patient's breast surface. During daily treatment, when the patient's DIBH reached preset AlignRT tolerance of ±3mm for all principle directions (vertical, longitudinal, and lateral), the remaining longitudinal offset was recorded...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048704/mo-fg-bra-09-towards-an-optimal-breath-holding-procedure-for-radiotherapy-differences-in-organ-motion-during-inhalation-and-exhalation-breath-holds
#17
E Lens, O Gurney-Champion, A van der Horst, D Tekelenburg, Z van Kesteren, M Parkes, G van Tienhoven, A Nederveen, A Bel
PURPOSE: Breath-holding (BH) is often used to reduce organ motion during radiotherapy. The aim of this study was to determine the differences in pancreatic and diaphragmatic motion during BH between inhalation and exhalation BHs with variable lung volumes and to investigate whether motion increases/decreases during BH. METHODS: Sixteen healthy volunteers were asked to perform four different 60-second BHs, from fully inflated to fully deflated lungs (i.e. lung volumes of: 100%, ∼70%, ∼30% and 0% of inspiratory capacity) three times (total of 192 BHs)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048690/su-f-j-22-lung-volumevariability-assessed-by-bh-cbct-in-3d-surface-image-guided-deep-inspirationbreath-hold-dibh-radiotherapy-for-left-sided-breast-cancer
#18
A Gutierrez, D Stanley, N Papanikolaou, R Crownover
PURPOSE: With the increasing use of DIBH techniques for left-sided breast cancer, 3D surface-image guided DIBH techniques have improved patient setup and facilitated DIBH radiation delivery. However, quantification of the daily separation between the heart and left breast still presents a challenge. One method of assuring separation is to ensure consistent left lung filling. With this in mind, the aim of this study is to retrospectively quantify left lung volume from weekly breath hold-CBCTs (bh-CBCT) of left-sided breast patients treated using a 3D surface imaging system...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048600/su-f-t-514-evaluation-of-the-accuracy-of-free-breathing-and-deep-inspiration-breath-hold-gated-beam-delivery-using-an-elekta-linac
#19
M Jermoumi, R Xie, D Cao, D Housley, D Shepard
PURPOSE: In this study, we evaluated the performance of an Elekta linac in the delivery of gated radiotherapy. We examined whether the use of either a short gating window or a long beam hold impacts the accuracy of the delivery METHODS: The performance of an Elekta linac in the delivery of gated radiotherapy was assessed using a 20cmX 20cm open field with the radiation delivered using a range of beam-on and beam-off time periods. Two SBRT plans were used to examine the accuracy of gated beam delivery for clinical treatment plans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048390/su-f-t-415-differences-in-lung-sparing-in-deep-inspiration-breath-hold-and-free-breathing-breast-plans-calculated-in-pinnacle-and-monaco
#20
D Saenz, S Stathakis
PURPOSE: Deep inspiration breath-hold (DIBH) is used for left-sided breast radiotherapy to spare the heart and lung. The magnitude of sparing has been shown to be significant. Monte Carlo, furthermore, has the potential to calculate most accurately the dose in the heterogeneous lung medium at the interface with the lung wall. The lung dose was investigated in Monaco to determine the level of sparing relative to that calculated in Pinnacle(3) . METHODS: Five patients undergoing DIBH radiotherapy on an Elekta Versa HD linear accelerator in conjunction with the Catalyst C-RAD surface imaging system were planned using Phillips Pinnacle(3) ...
June 2016: Medical Physics
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