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https://www.readbyqxmd.com/read/29789896/an-offline-technique-to-evaluate-residual-motion-of-the-diaphragm-during-deep-inspiratory-breath-hold-from-cone-beam-ct-datasets
#1
Manuel Blessing, Julian Hofmann, Lena Vogel, Judit Boda-Heggemann, Frank Lohr, Frederik Wenz, Florian Stieler, Anna Simeonova-Chergou
PURPOSE: In radiation therapy, the computer-assisted deep inspiration breath-hold (DIBH) technique is one approach to deal with respiratory motion of tumors in the lung, liver, or upper abdomen. However, inter- and intra-breath-hold deviations from an optimal static tumor position might occur. A novel method is presented to noninvasively measure the diaphragm position and thus estimate its residual deviation (as surrogate for the tumor position) based on cone-beam computed tomography (CBCT) projection data using active breathing control during acquisition...
May 22, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29785834/development-of-a-robust-mri-fiducial-system-for-automated-fusion-of-mr-us-abdominal-images
#2
Christopher P Favazza, Krzysztof R Gorny, Matthew R Callstrom, Anil N Kurup, Michael Washburn, Pamela S Trester, Charles L Fowler, Nicholas J Hangiandreou
We present the development of a two-component magnetic resonance (MR) fiducial system, that is, a fiducial marker device combined with an auto-segmentation algorithm, designed to be paired with existing ultrasound probe tracking and image fusion technology to automatically fuse MR and ultrasound (US) images. The fiducial device consisted of four ~6.4 mL cylindrical wells filled with 1 g/L copper sulfate solution. The algorithm was designed to automatically segment the device in clinical abdominal MR images...
May 21, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29773686/drivers-of-the-dive-response-in-pinnipeds-apnea-submergence-or-temperature
#3
Jeppe Kaczmarek, Colleen Reichmuth, Birgitte I McDonald, Jakob H Kristensen, Josefin Larson, Fredrik Johansson, Jenna L Sullivan, Peter T Madsen
Long and deep dives in marine mammals are enabled by high mass-specific oxygen stores and the dive response (DR), which reduces oxygen consumption in concert with increased peripheral vasoconstriction and a lowered heart rate during dives. Diving heart rates of pinnipeds are highly variable and modulated by many factors, such as breath holding (apnea), pressure, swimming activity, temperature, and even cognitive control. However, the individual effects of these factors on diving heart rate are poorly understood due to the difficulty of parsing their relative contributions in diving pinnipeds...
May 17, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29773446/effects-of-preparatory-coaching-and-home-practice-for-deep-inspiration-breath-hold-on-cardiac-dose-for-left-breast-radiation-therapy
#4
A Kim, A M Kalet, N Cao, D S Hippe, L C Fang, L Young, J Meyer, E V Lang, N A Mayr
AIMS: Deep inspiration breath hold (DIBH) reduces cardiac radiation exposure by creating cardiac-chest wall separation in breast cancer radiotherapy. DIBH requires sustaining chest wall expansion for up to 40 s and involves complex co-ordination of thoraco-abdominal muscles, which may not be intuitive to patients. We investigated the effect of in-advance preparatory DIBH coaching and home practice on cardiac doses. MATERIALS AND METHODS: Successive patients from 1 February 2015 to 31 December 2016 with left-sided breast cancer who underwent tangential field radiotherapy utilising the DIBH technique were included...
May 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29771557/distress-tolerance-associations-with-trauma-and-substance-cue-reactivity-in-low-income-inner-city-adults-with-substance-use-disorders-and-posttraumatic-stress
#5
Anka A Vujanovic, Margaret C Wardle, Jafar Bakhshaie, Lia J Smith, Charles E Green, Scott D Lane, Joy M Schmitz
Cue reactivity has great potential to advance our understanding of posttraumatic stress disorder (PTSD), substance use disorder (SUD), and PTSD/SUD comorbidity. The present investigation examined distress tolerance (DT) with regard to trauma and substance cue reactivity. Participants included 58 low-income, inner-city adults (49.1% women; Mage = 45.73, SD = 10.00) with substance dependence and at least 4 symptoms of PTSD. A script-driven cue reactivity paradigm was utilized. Four DT measures were administered, including the Distress Tolerance Scale (DTS), Mirror-Tracing Persistence Task (MTPT), Breath-Holding Task (BH), and Paced Auditory Serial Addition Task (PASAT)...
May 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/29761336/-syncope-in-children-and-adolescents
#6
REVIEW
Matthias J Müller, Thomas Paul
Syncope is common in children and adolescents. Neurally mediated syncope including pallid and cyanotic breath holding spells, vagovasal syncope and neurocardiogenic syncope is based on a common pathomechanism and accounts for approximately 75% of cases. A potentially life-threatening cardiac cause of syncope may be present in up to 6%. Detailed history, physical examination and 12-lead electrocardiogram (ECG) allow discrimination between benign and serious syncope in the majority of pediatric patients. Tilt-testing can be useful when diagnosis is unclear...
May 14, 2018: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29761316/impact-of-visual-feedback-on-dose-volume-histograms-for-organs-at-risk-in-postoperative-radiotherapy-with-deep-inspiration-breath-holding-for-patients-treated-with-breast-conserving-therapy-a-planning-study
#7
Keiko Nemoto Murofushi, Masaru Nakajima, Tetsuya Tomita, Minako Sumi, Yasuo Yoshioka, Masahiko Oguchi, Hideyuki Sakurai
BACKGROUND: We evaluated the effectiveness of visual feedback (VF) on radiotherapy with deep inspiration breath-holding (DIBH), and reviewed the dose for organs at risk (OARs). METHODS: Respiratory motions during DIBH for 15 s were monitored during planning computed tomography (CT)-scanning and simulation for 40 patients after breast-conserving surgery from June 2007 to February 2008. For 22 of 40 patients, a goggle-type liquid crystal display monitor was used for VF...
May 14, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29755846/repeatability-of-fdg-pet-ct-metrics-assessed-in-free-breathing-and-deep-inspiration-breath-hold-in-lung-cancer-patients
#8
Lotte Nygård, Marianne C Aznar, Barbara M Fischer, Gitte F Persson, Charlotte B Christensen, Flemming L Andersen, Mirjana Josipovic, Seppo W Langer, Andreas Kjær, Ivan R Vogelius, Søren M Bentzen
We measured the repeatability of FDG PET/CT uptake metrics when acquiring scans in free breathing (FB) conditions compared with deep inspiration breath hold (DIBH) for locally advanced lung cancer. Twenty patients were enrolled in this prospective study. Two FDG PET/CT scans per patient were conducted few days apart and in two breathing conditions (FB and DIBH). This resulted in four scans per patient. Up to four FDG PET avid lesions per patient were contoured. The following FDG metrics were measured in all lesions and in all four scans: Standardized uptake value (SUV)peak , SUVmax , SUVmean , metabolic tumor volume (MTV) and total lesion glycolysis (TLG), based on an isocontur of 50% of SUVmax ...
2018: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29755217/immediate-effects-of-yoga-breathing-with-intermittent-breath-holding-on-response-inhibition-among-healthy-volunteers
#9
Apar Avinash Saoji, B R Raghavendra, S K Rajesh, N K Manjunath
Background: There is very little evidence available on the effects of yoga-based breathing practices on response inhibition. The current study used stop-signal paradigm to assess the effects of yoga breathing with intermittent breath holding (YBH) on response inhibition among healthy volunteers. Materials and Methods: Thirty-six healthy volunteers (17 males + 19 females), with mean age of 20.31 ± 3.48 years from a university, were recruited in a within-subject repeated measures (RM) design...
May 2018: International Journal of Yoga
https://www.readbyqxmd.com/read/29750713/valsalva-maneuver-and-peripapillary-oct-angiography-vessel-density
#10
Gábor Holló
PURPOSE: To investigate the potential influence of breath holding on the results of peripapillary vessel density (VD) measurement with optical coherence tomography angiography (OCTA). METHODS: Three peripapillary VD measurements were made at 2-minute intervals on the right eye of 12 healthy young volunteers using the Angiovue/RTvue-XR OCT (software version 2017.1, Phase 7 update) without changing the head and body positions. During the first 2 measurements the volunteers were breathing normally...
May 10, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29750135/pitfalls-of-ovarian-ablative-magnetic-resonance-guided-radiation-therapy-for-refractory-endometriosis
#11
Shyama Tetar, Anna Bruynzeel, Omar Bohoudi, Theodoor Nieboer, Frank Lagerwaard
In this case presentation, we describe the challenges of performing magnetic resonance-guided radiation therapy (MRgRT) with plan adaptation in a patient with advanced endometriosis, in whom several prior therapeutic attempts were unsuccessful and extensive pelvic irradiation was regarded as being too toxic. Treatment was delivered in two sessions, first for the seemingly only active right ovary, and at a later stage for the left ovary. Some logistical problems were encountered during the preparation of the first treatment, which were subsequently optimized for the second treatment by using transvaginal ultrasound to determine the optimum time point for simulation and delivery...
March 9, 2018: Curēus
https://www.readbyqxmd.com/read/29750133/use-of-indirect-target-gating-in-magnetic-resonance-guided-liver-stereotactic-body-radiotherapy-case-report-of-an-oligometastatic-patient
#12
Luca Boldrini, Francesco Cellini, Stefania Manfrida, Giuditta Chiloiro, Stefania Teodoli, Davide Cusumano, Bruno Fionda, Gian Carlo Mattiucci, Anna Maria De Gaetano, Luigi Azario, Vincenzo Valentini
The case of a 73-year-old woman affected by anal canal cancer with concomitant liver metastases is presented here. The patient was addressed to stereotactic body radiotherapy (SBRT) on two hepatic secondary lesions after the first radiochemotherapy treatment of the primary tumor. A Tri-60-Co magnetic resonance hybrid radiotherapy unit was used for SBRT treatment delivery. Both liver lesions were not clearly visible on the setup magnetic resonance imaging (MRI) due to their limited dimensions (maximum diameter 13 mm); however, the presence of two cysts adjacent to the metastases allowed the use of an indirect target gating approach...
March 9, 2018: Curēus
https://www.readbyqxmd.com/read/29747708/efficacy-of-treatment-with-belladonna-in-children-with-severe-pallid-breath-holding-spells
#13
M Cecilia Gonzalez Corcia, Adrien Bottosso, Isabelle Loeckx, Françoise Mascart, Guy Dembour, Geneviève François
IntroductionPallid breath-holding spells are common and dramatic forms of recurrent syncope in infancy. They are very stressful despite their harmless nature and sometimes require treatment. OBJECTIVE: The objective of this study was to evaluate the efficacy of belladonna in severe breath-holding spells. METHODS: This is a multicentric, retrospective series involving 84 children with severe pallid breath-holding spells. Inclusion criteria were >1 pallid breath-holding spell with loss of consciousness, paediatric cardiology evaluation, and follow-up >6 months...
May 11, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29746482/implementation-of-a-voluntary-deep-inspiration-breath-hold-technique-vdibh-using-brainlab-exactrac-infrared-optical-tracking-system
#14
Edy Ippolito, Michele Fiore, Alessia Di Donato, Sonia Silipigni, Carla Rinaldi, Patrizia Cornacchione, Erminia Infusino, Cristina Di Venanzio, Carlo Greco, Lucio Trodella, Sara Ramella, Rolando Maria D'Angelillo
BACKGROUND: Voluntary deep inspiration breath hold technique (vDIBH) is considered as the key to achieving the widest cardiac sparing in whole breast irradiation. Several techniques have been implemented to achieve a reproducible, fast and friendly treatment. The aim of the present study is to implement vDIBH using the ExacTrac (BrainLAB AG, Germany) monitoring system. METHODS: Women with left-sided breast cancer, younger than 50 years or with cardiac disease, underwent whole breast RT with vDIBH using the ExacTrac (BrainLAB AG, Germany) monitoring system...
2018: PloS One
https://www.readbyqxmd.com/read/29744064/two-episodes-of-taravana-syndrome-in-a-breath-hold-diver-with-hyperhomocysteinemia
#15
Giuseppe Accurso, Andrea Cortegiani, Sabrina Caruso, Oriana Danile, Domenico Garbo, Pasquale Iozzo, Filippo Vitale, Santi Maurizio Raineri, Cesare Gregoretti, Antonino Giarratano
Taravana syndrome is a rare dysbaric disease characterized by neurologic signs and symptoms. Differently from others decompression illness, it has unspecified pathophysiology and unclear predisposing factors. Our cases suggest that thrombophilic state due to hyperhomocysteinemia could increase the risk to develop Taravana syndrome.
May 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29740971/target-position-reproducibility-in-left-breast-irradiation-with-deep-inspiration-breath-hold-using-multiple-optical-surface-control-points
#16
Aurora Fassi, Giovanni B Ivaldi, Paola Tabarelli de Fatis, Marco Liotta, Ilaria Meaglia, Patrizia Porcu, Lea Regolo, Marco Riboldi, Guido Baroni
The aim of this study was to investigate the use of 3D optical localization of multiple surface control points for deep inspiration breath-hold (DIBH) guidance in left-breast radiotherapy treatments. Ten left-breast cancer patients underwent whole-breast DIBH radiotherapy controlled by the Real-time Position Management (RPM) system. The reproducibility of the tumor bed (i.e., target) was assessed by the position of implanted clips, acquired through in-room kV imaging. Six to eight passive fiducials were positioned on the patients' thoraco-abdominal surface and localized intrafractionally by means of an infrared 3D optical tracking system...
May 8, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29730991/feasibility-of-cardiovascular-magnetic-resonance-to-detect-oxygenation-deficits-in-patients-with-multi-vessel-coronary-artery-disease-triggered-by-breathing-maneuvers
#17
Kady Fischer, Kyohei Yamaji, Silvia Luescher, Yasushi Ueki, Bernd Jung, Hendrik von Tengg-Kobligk, Stephan Windecker, Matthias G Friedrich, Balthasar Eberle, Dominik P Guensch
BACKGROUND: Hyperventilation with a subsequent breath-hold has been successfully used as a non-pharmacological vasoactive stimulus to induce changes in myocardial oxygenation. The purpose of this pilot study was to assess if this maneuver is feasible in patients with multi-vessel coronary artery disease (CAD), and if it is effective at detecting coronary artery stenosis > 50% determined by quantitative coronary angiography (QCA). METHODS: Twenty-six patients with coronary artery stenosis (QCA > 50% diameter stenosis) underwent a contrast-free cardiovascular magnetic resonance (CMR) exam in the time interval between their primary coronary angiography and a subsequent percutaneous coronary intervention (PCI, n = 24) or coronary artery bypass (CABG, n = 2) revascularization procedure...
May 7, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29729010/lung-morphometry-using-hyperpolarized-129-xe-multi-b-diffusion-mri-with-compressed-sensing-in-healthy-subjects-and-patients-with-copd
#18
Huiting Zhang, Junshuai Xie, Sa Xiao, Xiuchao Zhao, Ming Zhang, Lei Shi, Ke Wang, Guangyao Wu, Xianping Sun, Chaohui Ye, Xin Zhou
PURPOSE: To demonstrate the feasibility of compressed sensing (CS) to accelerate the acquisition of hyperpolarized (HP) 129 Xe multi-b diffusion MRI for quantitative assessments of lung microstructural morphometry. METHODS: Six healthy subjects and six chronic obstructive pulmonary disease (COPD) subjects underwent HP 129 Xe multi-b diffusion MRI (b = 0, 10, 20, 30, and 40 s/cm2 ). First, a fully sampled (FS) acquisition of HP 129 Xe multi-b diffusion MRI was conducted in one healthy subject...
May 4, 2018: Medical Physics
https://www.readbyqxmd.com/read/29728744/free-breathing-quantification-of-hepatic-fat-in-healthy-children-and-children-with-nonalcoholic-fatty-liver-disease-using-a-multi-echo-3-d-stack-of-radial-mri-technique
#19
Tess Armstrong, Karrie V Ly, Smruthi Murthy, Shahnaz Ghahremani, Grace Hyun J Kim, Kara L Calkins, Holden H Wu
BACKGROUND: In adults, noninvasive chemical shift encoded Cartesian magnetic resonance imaging (MRI) and single-voxel magnetic resonance (MR) spectroscopy (SVS) accurately quantify hepatic steatosis but require breath-holding. In children, especially young and sick children, breath-holding is often limited or not feasible. Sedation can facilitate breath-holding but is highly undesirable. For these reasons, there is a need to develop free-breathing MRI technology that accurately quantifies steatosis in all children...
May 4, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29726838/estimating-regions-of-air-trapping-from-electrical-impedance-tomography-data
#20
Jennifer L Mueller, Peter A Muller, Michelle Mellenthin, Rashmi Murthy, Michael Capps, Melody Alsaker, Robin Deterding, Scott D Sagel, Emily DeBoer
OBJECTIVE: Electrical impedance tomography (EIT) has been shown as a viable non-invasive, bedside imaging modality to monitor lung function.This paper introduces a method for identifying regions of air trapping from EIT data collected during tidal breathing and breath-holding maneuvers. APPROACH: Ventilation-perfusion index maps are computed from dynamic EIT images. These maps are then used to identify regions of air trapping in the area of the lung as regions that are poorly ventilated but well perfused throughout the breathing and cardiac cycles...
May 4, 2018: Physiological Measurement
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