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https://www.readbyqxmd.com/read/29749641/antioxidant-rich-foods-and-response-to-altitude-training-a-randomized-controlled-trial-in-elite-endurance-athletes
#1
Anu Elisa Koivisto, Gøran Paulsen, Ingvild Paur, Ina Garthe, Espen Tønnessen, Truls Raastad, Nasser Ezzatkhah Bastani, Jostein Hallén, Rune Blomhoff, Siv Kjølsrud Bøhn
High doses of isolated antioxidant supplements such as vitamin C and E, have demonstrated the potential to blunt cellular adaptations to training It is, however, unknown whether intake of high doses of antioxidants from foods has similar effects. Hence, the aim of the study was to investigate whether intake of antioxidant-rich foods affects adaptations to altitude training in elite athletes. In a randomized controlled trial, 31 national team endurance athletes (23 ± 5 years), ingested antioxidant-rich foods (n=16) or eucaloric control foods (n=15) daily during a 3-week altitude training camp (2320 m)...
May 11, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29705603/hypobaric-hypoxia-impairs-cued-and-contextual-fear-memory-in-rats
#2
Punita Kumari, Hina Kauser, Meetu Wadhwa, Koustav Roy, Shahnawaz Alam, Surajit Sahu, Krishna Kishore, Koushik Ray, Usha Panjwani
Fear memory is essential for survival, and its dysregulation leads to disorders. High altitude hypobaric hypoxia (HH) is known to induce cognitive decline. However, its effect on fear memory is still an enigma. We aimed to investigate the temporal effect of HH on fear conditioning and the underlying mechanism. Adult male Sprague-Dawley rats were trained for fear conditioning and exposed to simulated HH equivalent to 25,000 ft for different durations (1, 3, 7, 14 and 21 days). Subsequently, rats were tested for cued and contextual fear conditioning...
April 26, 2018: Brain Research
https://www.readbyqxmd.com/read/29695978/the-effects-of-altitude-training-on-erythropoietic-response-and-hematological-variables-in-adult-athletes-a-narrative-review
#3
REVIEW
Kamila Płoszczyca, Józef Langfort, Miłosz Czuba
Background: One of the goals of altitude training is to increase blood oxygen-carrying capacity in order to improve sea-level endurance performance in athletes. The elevated erythropoietin (EPO) production in hypoxia is a key factor in the achievement of enhanced hematological variables. The level of the EPO increase and acceleration of erythropoiesis depend on the duration of exposure and degree of hypoxia. Furthermore, many other factors may affect the hematological response to altitude training. Aim: The purpose of this narrative review was to: (1) analyze the kinetics of EPO and hematological variables during and after altitude training; (2) summarize the current state of knowledge about the possible causes of individual or cohort differences in EPO and hematological response to altitude training; (3) formulate practical guidelines for athletes to improve the efficiency of altitude training...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29653429/gis-based-groundwater-potential-analysis-using-novel-ensemble-weights-of-evidence-with-logistic-regression-and-functional-tree-models
#4
Wei Chen, Hui Li, Enke Hou, Shengquan Wang, Guirong Wang, Mahdi Panahi, Tao Li, Tao Peng, Chen Guo, Chao Niu, Lele Xiao, Jiale Wang, Xiaoshen Xie, Baharin Bin Ahmad
The aim of the current study was to produce groundwater spring potential maps using novel ensemble weights-of-evidence (WoE) with logistic regression (LR) and functional tree (FT) models. First, a total of 66 springs were identified by field surveys, out of which 70% of the spring locations were used for training the models and 30% of the spring locations were employed for the validation process. Second, a total of 14 affecting factors including aspect, altitude, slope, plan curvature, profile curvature, stream power index (SPI), topographic wetness index (TWI), sediment transport index (STI), lithology, normalized difference vegetation index (NDVI), land use, soil, distance to roads, and distance to streams was used to analyze the spatial relationship between these affecting factors and spring occurrences...
April 10, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29623089/real-time-human-detection-for-aerial-captured-video-sequences-via-deep-models
#5
Nouar AlDahoul, Aznul Qalid Md Sabri, Ali Mohammed Mansoor
Human detection in videos plays an important role in various real life applications. Most of traditional approaches depend on utilizing handcrafted features which are problem-dependent and optimal for specific tasks. Moreover, they are highly susceptible to dynamical events such as illumination changes, camera jitter, and variations in object sizes. On the other hand, the proposed feature learning approaches are cheaper and easier because highly abstract and discriminative features can be produced automatically without the need of expert knowledge...
2018: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/29608739/submaximal-exercise-testing-at-low-altitude-for-prediction-of-exercise-tolerance-at-high-altitude
#6
Martin Burtscher, Michael Philadelphy, Hannes Gatterer, Johannes Burtscher, Rudolf Likar
Annually, thousands of air travellers visit high altitude destinations to enjoy hiking tours to attractions in surrounding areas. However, many of them are not adequately trained, not sufficiently acclimatized and/or may suffer from pre-existing diseases. To prevent adverse health effects and unpleasant experiences at high altitude, simple submaximal exercise testing at low altitude for the prediction of exercise tolerance at high altitude would be helpful. Therefore, 40 healthy males and females performed submaximal exercise tests at low (600 m) and high altitude (3500 m)...
January 1, 2018: Journal of Travel Medicine
https://www.readbyqxmd.com/read/29575975/oxidative-stress-in-elite-athletes-training-at-moderate-altitude-and-at-sea-level
#7
Josefa León-López, Carmen Calderón-Soto, Matías Pérez-Sánchez, Belén Feriche, Xavier Iglesias, Diego Chaverri, Ferran A Rodréguez
Using a controlled parallel group longitudinal trial design, we investigated the effects of different training interventions on the prooxidant/antioxidant status of elite athletes: living and training at moderate altitude for 3 (Hi-Hi3) and 4 weeks (Hi-Hi), and for 4 weeks too, living high and training high and low (Hi-HiLo) and living and training at sea level (Lo-Lo). From 61 swimmers, 54 completed the study. Nitrites, carbonyls, and lipid peroxidation (LPO) levels were assessed in plasma. Enzymatic antioxidants glutathione peroxidase (GPx) and glutathione reductase (GRd), and non-enzymatic antioxidants total glutathione (GST), reduced glutathione (GSH) and oxidized glutathione (GSSG) were analysed in the erythrocyte fraction...
March 24, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29541032/the-influence-of-co-2-and-exercise-on-hypobaric-hypoxia-induced-pulmonary-edema-in-rats
#8
Ryan L Sheppard, Joshua M Swift, Aaron Hall, Richard T Mahon
Introduction: Individuals with a known susceptibility to high altitude pulmonary edema (HAPE) demonstrate a reduced ventilation response and increased pulmonary vasoconstriction when exposed to hypoxia. It is unknown whether reduced sensitivity to hypercapnia is correlated with increased incidence and/or severity of HAPE, and while acute exercise at altitude is known to exacerbate symptoms the effect of exercise training on HAPE susceptibility is unclear. Purpose: To determine if chronic intermittent hypercapnia and exercise increases the incidence of HAPE in rats...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29538179/intravenous-iron-does-not-augment-the-haemoglobin-mass-response-to-simulated-hypoxia
#9
Laura A Garvican-Lewis, Victor L Vuong, Andrew D Govus, Peter Peeling, Grace Jung, Elizabeta Nemeth, David Hughes, Greg Lovell, Daniel Eichner, Christopher J Gore
PURPOSE: Iron is integral for erythropoietic adaptation to hypoxia, yet the importance of supplementary iron compared to existing stores is poorly understood. The aim of the present study was to compare the magnitude of the haemoglobin mass (Hbmass) response to altitude in athletes supplemented with intravenous (IV), oral or placebo iron supplementation. METHODS: Thirty-four, non-anaemic, endurance-trained athletes completed 3 weeks of simulated altitude (3000 m, 14h...
March 12, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29526495/automated-detection-of-radioisotopes-from-an-aircraft-platform-by-pattern-recognition-analysis-of-gamma-ray-spectra
#10
Brian W Dess, John Cardarelli, Mark J Thomas, Jeff Stapleton, Robert T Kroutil, David Miller, Timothy Curry, Gary W Small
A generalized methodology was developed for automating the detection of radioisotopes from gamma-ray spectra collected from an aircraft platform using sodium-iodide detectors. Employing data provided by the U.S Environmental Protection Agency Airborne Spectral Photometric Environmental Collection Technology (ASPECT) program, multivariate classification models based on nonparametric linear discriminant analysis were developed for application to spectra that were preprocessed through a combination of altitude-based scaling and digital filtering...
March 8, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29517422/locomotor-respiratory-coupling-is-maintained-in-simulated-moderate-altitude-in-trained-distance-runners
#11
Timothy J Fulton, Hunter L Paris, Abigail S L Stickford, Allison H Gruber, Timothy D Mickleborough, Robert F Chapman
To determine if acute exposure to simulated moderate altitude alters locomotor-respiratory coupling (LRC) patterns in runners, 13 trained male distance runners performed a running economy and maximal oxygen uptake (V̇O2max ) test in normoxia (NORM) and hypoxia (HYP) (FIO2 = 15.8%; ~ 2400m / 8000ft) on separate days. Running economy (RE), the degree of LRC, stride frequency-to-breathing frequency quotients (SF/fb ), ratings of perceived exertion (RPE), and dyspnea (DYS) were assessed at three common submaximal speeds and V̇O2max ...
March 8, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29516744/interrelationships-between-changes-in-erythropoietin-plasma-volume-haemoglobin-concentration-and-total-haemoglobin-mass-in-endurance-athletes
#12
Dariusz Sitkowski, Zbigniew Szygula, Andrzej Pokrywka, Dariusz Turowski, Jadwiga Malczewska-Lenczowska
Interrelationships between physiological changes (Δ) in erythropoietin (EPO), plasma volume (PV), haemoglobin concentration ([Hb]), and total haemoglobin mass (tHb-mass) were examined in cyclists who trained in different altitudes. Regardless of differences in pattern of changes observed in three training locations, ΔEPO was correlated positively with ΔPV, negatively with Δ[Hb], and trivially with ΔtHb-mass. Δ[Hb] was negatively correlated with ΔPV. In the pooled data the Spearman's rank correlation coefficients were as follows: r = 0...
March 8, 2018: Research in Sports Medicine
https://www.readbyqxmd.com/read/29502890/issues-to-resolve-with-the-use-of-extracorporeal-membrane-oxygenation-during-interfacility-transportation
#13
P Burgueño, C González, A Sarralde, F Gordo
Extracorporeal membrane oxygenation (ECMO) support is indicated in patients who are refractory to treatment, those with cardiogenic shock or respiratory failure and those with exacerbations eligible for heart and lung transplantation. Physician experience and quantity of necessary resources are reasons why regionalization could benefit patients of this kind, establishing ECMO reference centers and integrating a transportation network specialized in ECMO. This type of transportation is a challenge for healthcare systems and physicians, given its greater complexity, requiring a multidisciplinary and inter-territorial approach...
March 1, 2018: Medicina Intensiva
https://www.readbyqxmd.com/read/29495152/-relationship-between-occupational-stress-and-working-ability-of-workers-in-a-petroleum-processing-enterprise-in-high-altitude-area
#14
X M Ma, H L Kang, C B Shi, Y Li, Y F Wu, Z H Liu, G Wang, H Y Lei
Objective: To investigate the relationship between occupational stress and working ability of workers in a petroleum processing enterprise in a high altitude area. Methods: A total of 728 workers in a petroleum processing enterprise at an altitude of 2850 m were subjected to a survey using Occupational Stress Inventory (OSI) , Work Ability Index (WAI) Scale, Occupational Role Questionnaire (ORQ) , Personal Strain Questionnaire (PSQ) , and Personal Resource Questionnaire (PRQ) from May 2014 to August 2016. Results: Of the 728 workers, 55 (7...
December 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/29469995/hypobaric-live-high-train-low-does-not-improve-aerobic-performance-more-than-live-low-train-low-in-cross-country-skiers
#15
P Robach, J Hansen, A Pichon, A-K Meinild Lundby, S Dandanell, G Slettaløkken Falch, D Hammarström, D H Pesta, C Siebenmann, S Keiser, P Kérivel, J E Whist, B R Rønnestad, C Lundby
Live high-train low (LHTL) using hypobaric hypoxia was previously found to improve sea-level endurance performance in well-trained individuals; however, confirmatory controlled data in athletes are lacking. Here, we test the hypothesis that natural-altitude LHTL improves aerobic performance in cross-country skiers, in conjunction with expansion of total hemoglobin mass (Hbmass , carbon monoxide rebreathing technique) promoted by accelerated erythropoiesis. Following duplicate baseline measurements at sea level over the course of 2 weeks, nineteen Norwegian cross-country skiers (three women, sixteen men, age 20 ± 2 year, maximal oxygen uptake (VO2 max) 69 ± 5 mL/min/kg) were assigned to 26 consecutive nights spent at either low (1035 m, control, n = 8) or moderate altitude (2207 m, daily exposure 16...
February 22, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29457371/validation-of-a-blood-marker-for-plasma-volume-in-endurance-athletes-during-a-live-high-train-low-altitude-training-camp
#16
Louisa M Lobigs, Laura A Garvican-Lewis, Victor L Vuong, Nicolin Tee, Christopher J Gore, Peter Peeling, Brian Dawson, Yorck O Schumacher
Altitude is a confounding factor within the Athlete Biological Passport (ABP) due, in part, to the plasma volume (PV) response to hypoxia. Here, a newly developed PV blood test is applied to assess the possible efficacy of reducing the influence of PV on the volumetric ABP markers; haemoglobin concentration ([Hb]) and the OFF-score. Endurance athletes (n=34) completed a 21-night simulated live-high train-low (LHTL) protocol (14 h.d-1 at 3000 m). Bloods were collected twice pre-altitude; at days 3, 8, and 15 at altitude; and 1, 7, 21, and 42 days post-altitude...
February 19, 2018: Drug Testing and Analysis
https://www.readbyqxmd.com/read/29455381/groundwater-potential-mapping-using-c5-0-random-forest-and-multivariate-adaptive-regression-spline-models-in-gis
#17
Ali Golkarian, Seyed Amir Naghibi, Bahareh Kalantar, Biswajeet Pradhan
Ever increasing demand for water resources for different purposes makes it essential to have better understanding and knowledge about water resources. As known, groundwater resources are one of the main water resources especially in countries with arid climatic condition. Thus, this study seeks to provide groundwater potential maps (GPMs) employing new algorithms. Accordingly, this study aims to validate the performance of C5.0, random forest (RF), and multivariate adaptive regression splines (MARS) algorithms for generating GPMs in the eastern part of Mashhad Plain, Iran...
February 17, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29431548/impact-of-energy-availability-health-and-sex-on-hemoglobin-mass-responses-following-lhth-altitude-training-in-elite-female-and-male-distance-athletes
#18
Ida A Heikura, Louise M Burke, Dan Bergland, Arja L T Uusitalo, Antti A Mero, Trent Stellingwerff
BACKGROUND: We investigated the effects of sex, energy availability (EA), and health status on the change in hemoglobin mass (ΔHbmass) in elite endurance athletes over ~3 to 4 weeks of Live-High/Train-High altitude training (Flagstaff, AZ, 2135m; n=27 females; n=21 males; 27% 2016 Olympians). METHODS: Pre- and post-camp Hbmass (optimized CO re-breathing method) and iron status were measured, EA was estimated via food and training logs and Low Energy Availability in Females Questionnaire (LEAF-Q) and a general injury/illness questionnaire was completed...
February 12, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29423544/high-intensity-interval-training-in-hypoxia-does-not-affect-muscle-hif-responses-to-acute-hypoxia-in-humans
#19
Stefan De Smet, Gommaar D'Hulst, Chiel Poffé, Ruud Van Thienen, Emanuele Berardi, Peter Hespel
PURPOSE: The myocellular response to hypoxia is primarily regulated by hypoxia-inducible factors (HIFs). HIFs thus conceivably are implicated in muscular adaptation to altitude training. Therefore, we investigated the effect of hypoxic versus normoxic training during a period of prolonged hypoxia ('living high') on muscle HIF activation during acute ischaemia. METHODS: Ten young male volunteers lived in normobaric hypoxia for 5 weeks (5 days per week, ~ 15.5 h per day, Fi O2 : 16...
April 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29420150/adaptations-in-muscle-oxidative-capacity-fiber-size-and-oxygen-supply-capacity-after-repeated-sprint-training-in-hypoxia-combined-with-chronic-hypoxic-exposure
#20
Stephan van der Zwaard, Franck Brocherie, Bengt L G Kom, Grégoire P Millet, Louise Deldicque, Willem J van der Laarse, Olivier Girard, Richard T Jaspers
In this study, we investigate adaptations in muscle oxidative capacity, fiber size and oxygen supply capacity in team-sport athletes after six repeated-sprint sessions in normobaric hypoxia or normoxia combined with 14 days of chronic normobaric hypoxic exposure. Lowland elite field hockey players resided at simulated altitude ({greater than or equal to}14 h∙d-1 at 2800-3000 m) and performed regular training plus six repeated-sprint sessions in normobaric hypoxia (3000 m; LHTLH; n=6) or normoxia (0 m, LHTL; n=6) or lived at sea level with regular training only (LLTL; n=6)...
February 8, 2018: Journal of Applied Physiology
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