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https://www.readbyqxmd.com/read/28214375/anti-fatigue-effects-of-troxerutin-on-exercise-endurance-capacity-oxidative-stress-and-mmp-9-levels-in-trained-male-rats
#1
Mohammad Zamanian, Mohammad R Hajizadeh, Ali Esmaeili Nadimi, Ali Shamsizadeh, Mohammad Allahtavakoli
The aim of this study was to investigate effects of troxerutin (TRX) on endurance capacity, oxidative stress and MMP-9 levels in trained male rats. Forty male Wistar rats were divided into five groups. The control (Vehicle) and exercise training (5 days/week) with vehicle treatment (Exercise), exercise training with TRX treatment at 75 (Ex-TRX75), 150 (Ex-TRX150), and 300 mg/kg (Ex-TRX300). The treated groups received TRX by gavage every day while the other groups received water for 30 days. On the 30(th) day, rats were sacrificed immediately after exhaustive swimming test, and some biochemical parameters were measured...
February 18, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/28187266/short-term-effects-of-troxerutin-vitamin-p4-on-muscle-fatigue-and-genes-expression-of-bcl-2-and-bax-in-the-hepatic-tissue-of-rats
#2
Mohammad Zamanian, Ali Shamsizadeh, Ali Esmaeili Nadimi, Mohammad R Hajizadeh, Fatemeh Allatavakoli, Mohammad R Rahmani, Ayat Kaeidi, Hamid R Safari Khalegh, Mohammad Allahtavakoli
In the current study, the effects of troxerutin (TXER) on muscle fatigue and genes expression of Bcl-2 and Bax in the hepatic tissue of rats was investigated. 40 male Wistar rats were randomly divided into four groups and designated as control and TXER treatment at 75 (TXER75), 150 (TXER150), and 300 mg/kg/day (TXER300). The treated groups and control group received TXER and water orally for 7 days. After an exhaustive swimming test on the 7th day, all animals were sacrificed immediately and several biochemical parameters related to fatigue and genes expression of Bcl-2 and Bax in the hepatic tissue were measured...
February 10, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28165424/changbai-mountain-ginseng-panax-ginseng-c-a-mey-extract-supplementation-improves-exercise-performance-and-energy-utilization-and-decreases-fatigue-associated-parameters-in-mice
#3
Guo-Dong Ma, Chun-Hui Chiu, Yi-Ju Hsu, Chien-Wen Hou, Yi-Ming Chen, Chi-Chang Huang
Changbai Mountain Ginseng (CMG, Panax ginseng C.A. Mey) is a traditional medicine commonly found in Northeast China and grows at elevations of 2000 m or higher in the Changbai Mountain Range. CMG, considered to be a "buried treasure medicine", is priced higher than other types of ginseng. However, few studies have demonstrated the effects of CMG supplementation on exercise performance, physical fatigue, and the biochemical profile. The major compound of CMG extract was characterized by electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS)...
February 5, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28163267/cornu-cervi-pantotrichum-supplementation-improves-physiological-adaptions-during-intensive-endurance-training
#4
Wen-Ching Huang, Chi-Chang Huang, Hsiao-Li Chuang, Wen-Chyuan Chen, Mei-Chich Hsu
Cornu cervi pantotrichum (CCP), used in traditional Chinese medicine, is a well-known yang-invigorating agent with multifunctional bioactivities. We previously showed, through an acute exercise challenge, that short-term CCP supplementation improved physical activities and fatigue-associated biochemical indices. Questions about the long-term effects of CCP treatment on exercise performance and physical fatigue, as well as safety, with intensive exercise training need further research. ICR-strain mice were randomly assigned to three groups: (1) sedentary control and vehicle treatment (SC); (2) exercise training with vehicle treatment (ET); (3) ET with CCP treatment at 4108 mg/kg/day (ET+CCP)...
February 3, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28145412/hydraulic-hydrogel-actuators-and-robots-optically-and-sonically-camouflaged-in-water
#5
Hyunwoo Yuk, Shaoting Lin, Chu Ma, Mahdi Takaffoli, Nicolas X Fang, Xuanhe Zhao
Sea animals such as leptocephali develop tissues and organs composed of active transparent hydrogels to achieve agile motions and natural camouflage in water. Hydrogel-based actuators that can imitate the capabilities of leptocephali will enable new applications in diverse fields. However, existing hydrogel actuators, mostly osmotic-driven, are intrinsically low-speed and/or low-force; and their camouflage capabilities have not been explored. Here we show that hydraulic actuations of hydrogels with designed structures and properties can give soft actuators and robots that are high-speed, high-force, and optically and sonically camouflaged in water...
February 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28141662/effects-of-a-dance-based-aquatic-exercise-program-in-obese-postmenopausal-women-with-knee-osteoarthritis-a-randomized-controlled-trial
#6
Jesús Casilda-López, Marie Carmen Valenza, Irene Cabrera-Martos, Ana Díaz-Pelegrina, Maria Paz Moreno-Ramírez, Gerald Valenza-Demet
OBJECTIVE: To evaluate the effects of a dance-based aquatic exercise program on functionality, cardiorespiratory capacity, postexercise heart rate, and fatigue in obese postmenopausal women with knee osteoarthritis. METHODS: A randomized controlled trial was performed. In all, 34 obese women diagnosed with knee osteoarthritis participated. Women were randomly allocated to an experimental group (n = 17) or a control group (n = 17). Participants in the experimental group were included in an 8-week dance-based aquatic exercise program conducted in community swimming pools...
January 30, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28121323/ingestion-of-soy-whey-blended-protein-augments-sports-performance-and-ameliorates-exercise-induced-fatigue-in-a-rat-exercise-model
#7
Guangxu Ren, Suqing Yi, Hongru Zhang, Jing Wang
This study sought to determine the effects of soy-whey blended protein supplementation on sports performance and related biochemical parameters after long-term training. After a week of adaptation, eighteen 6-week-old male Wistar rats were randomly assigned to 3 groups: the standard chow diet plus whey protein (Whey) group, the standard chow diet plus soy-whey blended protein (BP) group and the standard chow diet only (control) group. Each group included 6 rats for the seven-week experiment. Before the experiment, the baseline values of body weight, grasping force and time to exhaustion due to the loaded-swimming test were recorded for each group...
January 25, 2017: Food & Function
https://www.readbyqxmd.com/read/28121265/%C3%AE-alanine-supplementation-improves-throwing-velocities-in-repeated-sprint-ability-and-200-m-swimming-performance-in-young-water-polo-players
#8
Gabriel Machado Claus, Paulo Eduardo Redkva, Gabriel Mota Pinheiro Brisola, Elvis Sousa Malta, Rodrigo de Araujo Bonetti de Poli, Willian Eiji Miyagi, Alessandro Moura Zagatto
The purpose of this study was to investigate the effects of β-alanine supplementation on specific tests for water polo. Fifteen young water polo players (16±2years) underwent a 200-m swimming performance, repeated-sprint ability test (RSA) with free throw (shooting), and 30-s maximal teth-ered eggbeater kicks. Participants were randomly allocated into two groups (placebo x β-alanine) and supplemented with 6.4g∙day(-1) of β-alanine or a placebo for six weeks. The mean and total RSA times, the magnitude based inference analysis showed a likely beneficial effect for β-alanine sup-plementation (both 79...
January 25, 2017: Pediatric Exercise Science
https://www.readbyqxmd.com/read/28106808/anti-fatigue-effects-of-the-unique-polysaccharide-marker-of-dendrobium-officinale-on-balb-c-mice
#9
Wei Wei, Zhi-Peng Li, Tong Zhu, Hau-Yee Fung, Tin-Long Wong, Xin Wen, Dik-Lung Ma, Chung-Hang Leung, Quan-Bin Han
Dendrobium officinale extract shows potent anti-fatigue effects; however, the active substance responsible for these effects remains undetermined. A glucomannan with a huge molecular size of 730 kDa, called DOP, was identified as the unique authentication marker of this expensive herb. DOP exhibited immunomodulating effects on macrophages and lymphocytes in our previous study. Clinical reports also showed that people with fatigue syndrome have a disturbed immune system. Because DOP is the unique and dominant component of D...
January 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27995604/exercise-therapy-for-chronic-fatigue-syndrome
#10
REVIEW
Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen, Jonathan R Price
BACKGROUND: Chronic fatigue syndrome (CFS) is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headaches and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health problem. Treatment may include physical interventions, such as exercise therapy, which was last reviewed in 2004. OBJECTIVES: The objective of this review was to determine the effects of exercise therapy (ET) for patients with CFS as compared with any other intervention or control...
20, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27983571/anti-fatigue-effects-of-small-molecule-oligopeptides-isolated-from-panax-ginseng-c-a-meyer-in-mice
#11
Lei Bao, Xiaxia Cai, Junbo Wang, Yuan Zhang, Bin Sun, Yong Li
Panax ginseng C. A. Meyer (ginseng) is an edible and medicinal Chinese herb, which is often used in Asian countries for physical fitness. Ginseng is reported to have a wide range of biological activity and pharmaceutical properties. There were more studies on ginsenosides and polysaccharides, but fewer studies on ginseng oligopeptides (GOP), which are small molecule oligopeptides isolated from ginseng. The present study was designed to evaluate the anti-fatigue effects of GOP in mice and explore the possible underlying mechanism...
December 13, 2016: Nutrients
https://www.readbyqxmd.com/read/27983570/anti-fatigue-effect-by-peptide-fraction-from-protein-hydrolysate-of-croceine-croaker-pseudosciaena-crocea-swim-bladder-through-inhibiting-the-oxidative-reactions-including-dna-damage
#12
Yu-Qin Zhao, Li Zeng, Zui-Su Yang, Fang-Fang Huang, Guo-Fang Ding, Bin Wang
The swim bladder of the croceine croaker (Pseudosciaena crocea) was believed to have good curative effects in various diseases, including amnesia, insomnia, dizziness, anepithymia, and weakness after giving birth, in traditional Chinese medicine. However, there is no research focusing on the antioxidant and anti-fatigue peptides from croceine croaker swim bladders at present. Therefore, the purpose of this study was to investigate the bioactivities of peptide fractions from the protein hydrolysate of croceine croaker related to antioxidant and anti-fatigue effects...
December 13, 2016: Marine Drugs
https://www.readbyqxmd.com/read/27967270/effects-of-4-weeks-of-%C3%AE-alanine-supplementation-on-swim-performance-parameters-in-water-polo-players
#13
Gabriel Motta Pinheiro Brisola, Fabio Milioni, Marcelo Papoti, Alessandro Moura Zagatto
PURPOSE: In water polo several high-intensity efforts are performed, leading to the fatigue process due to accumulation of hydrogen ions, and thus β-alanine supplementation could be an efficient strategy to increase the intramuscular acid buffer. Therefore, the purpose of this study was to investigate whether 4 weeks of β-alanine supplementation enhances parameters related to water polo performance. METHODS: Twenty-two highly-trained male water polo players of national level were randomly assigned to receive either 28 days of β-alanine or a placebo (4...
December 14, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27937032/effects-of-naringin-on-physical-fatigue-and-serum-mmp-9-concentration-in-female-rats
#14
Mohammad Zamanian, Mohammadreza Hajizadeh, Ali Shamsizadeh, Mohammad Moemenzadeh, Morteza Amirteimouri, Mohammad Elshiekh, Mohammad Allahtavakoli
CONTEXT: Oxidative stress has a critical role in the development of physical fatigue and activation of matrix metalloproteinases-9 (MMP-9). Naringin (Nar) is a bioflavonoid that has antioxidant activity and suppresses MMP-9 expression. OBJECTIVE: The present study evaluates the anti-fatigue activity of Nar on physical fatigue and serum MMP-9 concentration in rats. MATERIALS AND METHODS: Fifty female Wistar rats were randomly divided into five groups (n = 10); a control group, vehicle group and three Nar treatment groups...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27834150/intranasal-delivery-of-microspheres-loaded-with-20-r-ginsenoside-rg3-enhances-anti-fatigue-effect-in-mice
#15
Wei Zhang, Xiaoyu Wang, Min Zhang, Min Xu, Wenyan Tang, Yi Zhang, Lei Lu, Jing Gao, Shen Gao
Nasal delivery of 20 (R) -ginsenoside Rg3 (Rg3) has a short-lived anti-fatigue effect owing to rapid clearance by nasal cilia. Thus, in order to extend the residence time of Rg3 in the nasal cavity, a new drug delivery system is needed. Chitosan microspheres loaded with Rg3 were prepared using a multi-step emulsification method. They had a spherical shape with a mean diameter of 44.9±12.6 µm. The drug-loading ratio was 10.25±0.08%, and the encapsulation ratio was 30.61±1.46%. Our in vitro mucoadhesion experiment demonstrated that 70...
November 9, 2016: Current Drug Delivery
https://www.readbyqxmd.com/read/27783320/lignans-rich-extract-from-herpetospermum-caudigerum-alleviate-physical-fatigue-in-mice
#16
Shi-Ying Jin, Rui-Sheng Li, Bao-de Shen, Jin-Xia Bai, Ping-Hua Xu, Ling Dai, He Xu, Shi-Xiao Jin, Jin Han, Hai-Long Yuan
OBJECTIVE: To ascertain anti-fatigue constituents and mechanisms of Herpetospermum caudigerum. METHODS: The 80% ethanol extracts of Herpetospermum caudigerum were partitioned with chloroform, ethyl acetate and n-butanol, respectively. Male Kunming mice were divided into 13 groups with 16 mice in each group: a control group fed with water, 9 groups treated with 3 fractions of Herpetospermum caudigerum (chloroform fraction, ethyl acetate fraction and n-butanol fraction) at dose of 80, 160 and 320 mg/kg for the low-dose group, medium-dose group and high-dose group, 3 herpetrione (HPE) treated groups fed with HPE at dose of 15, 30, and 60 mg/kg for the low-dose group, medium-dose group and high-dose group...
November 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27775591/capsaicin-supplementation-reduces-physical-fatigue-and-improves-exercise-performance-in-mice
#17
Yi-Ju Hsu, Wen-Ching Huang, Chien-Chao Chiu, Yan-Lin Liu, Wan-Chun Chiu, Chun-Hui Chiu, Yen-Shuo Chiu, Chi-Chang Huang
Chili pepper is used as a food, seasoning and has been revered for its medicinal and health claims. It is very popular and is the most common spice worldwide. Capsaicin (CAP) is a major pungent and bioactive phytochemical in chili peppers. CAP has been shown to improve mitochondrial biogenesis and adenosine triphosphate (ATP) production. However, there is limited evidence around the effects of CAP on physical fatigue and exercise performance. The purpose of this study was to evaluate the potential beneficial effects of CAP on anti-fatigue and ergogenic functions following physiological challenge...
October 20, 2016: Nutrients
https://www.readbyqxmd.com/read/27769804/the-effects-of-swimming-fatigue-on-shoulder-strength-range-of-motion-joint-control-and-performance-in-swimmers
#18
Martyn J Matthews, Daniel Green, Helen Matthews, Emma Swanwick
PURPOSE: To investigate the effects of training induced fatigue on shoulder strength, ROM, joint position sense, and stroke length in elite competitive swimmers. METHODS: Seventeen national level swimmers performed maximum isometric strength (internal and external rotation), ROM, and joint position sense tests before and after a fatiguing 8 × 100 m training set. Stroke length, heart rate, blood lactate and blood glucose levels were recorded throughout. RESULTS: Peak blood lactate, blood glucose levels, and heart rate increased significantly (P < 0...
January 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/27766021/dehydroepiandrosterone-supplementation-combined-with-whole-body-vibration-training-affects-testosterone-level-and-body-composition-in-mice
#19
Wen-Chyuan Chen, Yi-Ming Chen, Chi-Chang Huang, Yen-Dun Tzeng
Dehydroepiandrosterone (DHEA), the most abundant sex steroid, is primarily secreted by the adrenal gland and a precursor hormone used by athletes for performance enhancement. Whole-body vibration (WBV) is a well-known light-resistance exercise by automatic adaptations to rapid and repeated oscillations from a vibrating platform, which is also a simple and convenient exercise for older adults. However, the potential effects of DHEA supplementation combined with WBV training on to body composition, exercise performance, and hormone regulation are currently unclear...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27729861/placenta-peptide-can-protect-mitochondrial-dysfunction-through-inhibiting-ros-and-tnf-%C3%AE-generation-by-maintaining-mitochondrial-dynamic-network-and-by-increasing-il-6-level-during-chronic-fatigue
#20
Rekik A Muluye, Yuhong Bian, Li Wang, Paulos N Alemu, Huantian Cui, Xiaofei Peng, Shanshan Li
Background: Level of fatigue is related to the metabolic energy available to tissues and cells, mainly through mitochondrial respiration, as well fatigue is the most common symptom of poorly functioning mitochondria. Hence, dysfunction of these organelles may be the cause of the fatigue seen in Chronic fatigue (CF). Placenta has been used for treatment of fatigue and various disease, moreover peptides has known protect mitochondrial viability, and alleviate fatigue. These properties of placenta and peptides may link with its effect on mitochondria; therefore, it is highly important to investigate the effectiveness of placenta peptide on fatigue and mitochondrial dysfunction...
2016: Frontiers in Pharmacology
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