keyword
MENU ▼
Read by QxMD icon Read
search

blood bank

keyword
https://www.readbyqxmd.com/read/29791137/the-chemistry-of-lyophilized-blood-products
#1
Joseph Fernandez-Moure, Nuzhat Maisha, Erin B Lavik, Jeremy Cannon
With the development of new biologics and bioconjugates, storage and preservation have become more critical than ever before. Lyophilization is a method of cell and protein preservation by removing a solvent such as water from a substance followed by freezing. This technique has been used in the past and still holds promise for overcoming logistic challenges in safety net hospitals with limited blood banking resources, austere environments such as combat, and in mass casualty situations where existing resources may be outstripped...
May 23, 2018: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/29790503/a-voltammetric-method-for-fe-iii-in-blood-serum-using-a-screen-printed-electrode-modified-with-a-schiff-base-ionophore
#2
Susheel K Mittal, Sonia Rana, Navneet Kaur, Craig E Banks
Herein, a potent electrochemical ionophore (SMS-2) based on a Schiff base has been used for the modification of a screen-printed electrode (SPE). The modified disposable electrode can selectively detect ferric ions in an aqueous medium. Redox behavior of the proposed strip was characterized using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Incorporation of the ligand in the ink of the SPE enhanced the analytical performance of the electrode, and its surface modification was confirmed by SEM and EDX analysis...
May 23, 2018: Analyst
https://www.readbyqxmd.com/read/29789217/outcomes-and-cost-of-open-versus-endovascular-repair-of-intact-thoracoabdominal-aortic-aneurysm
#3
Satinderjit Locham, Hanaa Dakour-Aridi, Besma Nejim, Jasninder Dhaliwal, Widian Alshwaily, Mahmoud Malas
OBJECTIVE: Many previous studies have evaluated the outcomes of open and endovascular repair of thoracoabdominal aortic aneurysms (TAAAs). However, little is known about the differences in cost of these procedures and the potential factors driving these differences. The aim of this study was to evaluate the outcomes and cost of open aortic repair (OAR) vs endovascular repair of intact TAAA. METHODS: All patients undergoing repair for intact TAAA were identified in the Premier Healthcare Database (July 2009-March 2015)...
May 19, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29788937/seroprevalence-of-transfusion-transmissible-infections-hbv-hcv-syphilis-and-hiv-among-prospective-blood-donors-in-a-tertiary-health-care-facility-in-calabar-nigeria-an-eleven-years-evaluation
#4
Henshaw Uchechi Okoroiwu, Ifeyinwa Maryann Okafor, Enosakhare Aiyudubie Asemota, Dorathy Chioma Okpokam
BACKGROUND: Provision of constant and safe blood has been a public health challenge in Sub-Saharan Africa with high prevalence of transfusion-transmissible infections (TTIs). This study was aimed at determining the trend and seroprevalence of HBV, HCV, syphilis and HIV across the years within study among prospective blood donors at blood bank in University of Calabar Teaching Hospital (UCTH), Calabar, Nigeria. METHODS: A retrospective analysis of blood donor data from January 2005 to December 2016 was conducted in Blood Bank/Donor Clinic of University of Calabar Teaching Hospital, Calabar, Nigeria...
May 22, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29784641/intrinsic-apoptosis-circumvents-the-functional-decline-of-circulating-platelets-but-does-not-cause-the-storage-lesion
#5
Irina Pleines, Marion Lebois, Pradnya Gangatirkar, Amanda E Au, Rachael M Lane, Katya J Henley, Maria Kauppi, Jason Corbin, Ping Cannon, Jonathan Bernardini, Imala Alwis, Kate E Jarman, Sarah Ellis, Donald Metcalf, Shaun P Jackson, Simone M Schoenwaelder, Benjamin T Kile, Emma C Josefsson
The circulating life span of blood platelets is regulated by the pro-survival protein BCL-XL. It restrains the activity of BAK and BAX, the essential pro-death mediators of intrinsic apoptosis. Disabling the platelet intrinsic apoptotic pathway in mice by deleting BAK and BAX results in a doubling of platelet life span and concomitant thrombocytosis. Apoptotic platelets expose phosphatidylserine (PS) via a mechanism that is distinct from that driven by classical agonists. Whether there is any role for apoptotic PS in platelet function in vivo, however, is unclear...
May 21, 2018: Blood
https://www.readbyqxmd.com/read/29784518/impact-of-blood-donor-sex-on-transfusion-related-outcomes-in-preterm-infants
#6
Thomas Murphy, Anju Chawla, Richard Tucker, Betty Vohr
OBJECTIVE: Explore the role of red blood cell donor sex on preterm infant neonatal outcomes. STUDY DESIGN: In a retrospective, exploratory, cohort study, the hospital blood bank database was queried for units of blood released to neonatal intensive care unit patients in 2009-2010. The state blood center provided donor sex, and a department database provided neonatal characteristics and morbidities. Comparisons were made for 2 groups: those who ever received female blood and those who did not...
May 18, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29777574/factors-influencing-the-umbilical-cord-blood-stem-cell-industry-an-evolving-treatment-landscape
#7
REVIEW
Carla Dessels, Marco Alessandrini, Michael Sean Pepper
Hematopoietic stem cell transplantation (HSCT) is common practice today for life threatening malignant and non-malignant diseases of the blood and immune systems. Umbilical cord blood (UCB) is rich in hematopoietic stem cells (HSCs) and is an attractive alternative to harvesting HSCs from bone marrow or when mobilized into peripheral blood. One of the most appealing attributes of UCB is that it can be banked for future use and hence provides an off-the-shelf solution for patients in urgent need of a transplantation...
May 18, 2018: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29777083/finding-suitable-donors-for-feline-blood-banking
#8
John Hill, Wendy Barnett, Harvey Locke, Chris Laurence, Jenny Helm
No abstract text is available yet for this article.
May 19, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29771998/risk-factors-for-inappropriate-blood-requisition-among-hospitals-in-tanzania
#9
Wilhellmuss I Mauka, Tara B Mtuy, Michael J Mahande, Sia E Msuya, Innocent B Mboya, Abdul Juma, Rune N Philemon
BACKGROUND: Blood is a critical aspect of treatment in life saving situations, increasing demand. Blood requisition practices greatly effect sufficient supply in blood banks. This study aimed to determine the risk factors for inappropriate blood requisition in Tanzania. METHODS: This was a cross sectional study using secondary data of 14,460 patients' blood requests from 42 transfusion hospitals. Primary data were obtained by using cluster-sampling design. Data were analysed using a two-level mixed-effects Poisson regression to determine fixed-effects of individual-level factors and hospital level factors associated with inappropriate blood requests...
2018: PloS One
https://www.readbyqxmd.com/read/29767761/significance-of-hbv-nat-among-hbs-antigen-negative-blood-donors-in-saudi-arabia
#10
Nessrin Ghazi Alabdallat, Abdul Aziz A Bin Dukhyil
Background: Bloodborne hepatitis B virus (HBV) transmission from asymptomatic donors with acute HBV infections who have undetectable surface antigen of HBV (HBsAg), or from donors with chronic infections in whom serological markers were not detected, could cause residual infections leading to relevant transfusion-transmitted infections (RTTIs). HBV nucleic acid testing (NAT) can detect HBV DNA in the HBsAg-negative and total hepatitis B core antibody (anti-HBc)-negative window period of infection and in chronic cases...
May 15, 2018: Laboratory Medicine
https://www.readbyqxmd.com/read/29766665/identification-of-the-novel-hla-drb1-allele-drb1-14-183-in-a-colombian-umbilical-cord-blood-bank-donor
#11
L-X González-Acero, B Camacho, A M Perdomo-Arciniegas
HLA-DRB1*14:183 has two nucleotide changes from HLA-DRB1-13:44, D to E and F to Y. This article is protected by copyright. All rights reserved.
May 15, 2018: HLA
https://www.readbyqxmd.com/read/29765424/public-awareness-on-cord-blood-banking-in-saudi-arabia
#12
Dunia Jawdat, Sulaiman AlTwijri, Hadeel AlSemari, Mayssa Saade, Ahmed Alaskar
Background: In the last decade, cord blood (CB) has proven to be a valuable source of hematopoietic stem cells for transplantation to treat many hematological disorders. Since then, many CB banks have been established worldwide. Our aim was to estimate the level of public awareness of CB banking in Saudi Arabia. Study Design and Methods: A self-administered questionnaire of 22 multiple choices was conveniently distributed, consisting of demographics, awareness measure, attitude toward banking preference, and donation for research data...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29752869/allogeneic-umbilical-cord-blood-infusion-for-adults-with-ischemic-stroke-clinical-outcomes-from-a-phase-1-safety-study
#13
Daniel T Laskowitz, Ellen R Bennett, Rebecca J Durham, John J Volpi, Jonathan R Wiese, Michael Frankel, Elizabeth Shpall, Jeffry M Wilson, Jesse Troy, Joanne Kurtzberg
Stroke is a major cause of death and long-term disability, affecting one in six people worldwide. The only currently available approved pharmacological treatment for ischemic stroke is tissue plasminogen activator; however, relatively few patients are eligible for this therapy. We hypothesized that intravenous (IV) infusion of banked unrelated allogeneic umbilical cord blood (UCB) would improve functional outcomes in patients with ischemic stroke. To investigate this, we conducted a phase 1 open-label trial to assess the safety and feasibility of a single IV infusion of non-human leukocyte antigen (HLA) matched, ABO matched, unrelated allogeneic UCB into adult stroke patients...
May 12, 2018: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29752867/topical-application-of-culture-expanded-cd34-umbilical-cord-blood-cells-from-frozen-units-accelerates-healing-of-diabetic-skin-wounds-in-mice
#14
Jennifer Whiteley, Theresa Chow, Hibret Adissu, Armand Keating, Ian M Rogers
Chronic and nonhealing wounds are constant health issues facing patients with type 2 diabetes. As the incidence of type 2 diabetes mellitus (T2DM) increases, the incidence of chronic wounds and amputations will rise. T2DM is associated with peripheral arterial occlusive disease, which leads to the development of nonhealing skin ulcers after minor trauma. Patients develop severe pain limiting their mobility and ability to work and take care of themselves thus putting a significant burden on the family and society...
May 12, 2018: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29751949/platelet-storage-lesions-what-more-do-we-know-now
#15
REVIEW
Monica Suet Ying Ng, John-Paul Tung, John Francis Fraser
Platelet concentrate (PC) transfusions are a lifesaving adjunct to control and prevent bleeding in cancer, hematologic, surgical, and trauma patients. Platelet concentrate availability and safety are limited by the development of platelet storage lesions (PSLs) and risk of bacterial contamination. Platelet storage lesions are a series of biochemical, structural, and functional changes that occur from blood collection to transfusion. Understanding of PSLs is key for devising interventions that prolong PC shelf life to improve PC access and wastage...
April 17, 2018: Transfusion Medicine Reviews
https://www.readbyqxmd.com/read/29750797/critical-depth-raman-spectroscopy-enables-home-use-non-invasive-glucose-monitoring
#16
Signe M Lundsgaard-Nielsen, Anders Pors, Stefan O Banke, Jan E Henriksen, Dietrich K Hepp, Anders Weber
One of the most ambitious endeavors in the field of diabetes technology is non-invasive glucose sensing. In the past decades, a number of different technologies have been assessed, but none of these have found its entry into general clinical use. We report on the development of a table-top confocal Raman spectrometer that was used in the home of patients with diabetes and operated for extended periods of time unsupervised and without recalibration. The system is based on measurement of glucose levels at a 'critical depth' in the skin, specifically in the interstitial fluid located below the stratum corneum but above the underlying adipose tissue layer...
2018: PloS One
https://www.readbyqxmd.com/read/29750375/the-ontario-birth-study-a-prospective-pregnancy-cohort-study-integrating-perinatal-research-into-clinical-care
#17
Laura N Anderson, Julia A Knight, Rayjean J Hung, Sheryl L Hewko, Ryan A Seeto, Mary-Jean Martin, Alison Fleming, Jonathon L Maguire, Stephen G Matthews, Kellie E Murphy, Nan Okun, Jennifer M Jenkins, Stephen J Lye, Alan Bocking
BACKGROUND: Pregnancy and early childhood represent critical periods that impact health throughout the life-course. The Ontario Birth Study (OBS) is a pregnancy cohort study designed as a platform for research on pregnancy complications, maternal and infant health, and the developmental origins of health and disease. METHODS: Pregnant women <17 weeks gestational age were recruited between 2013 and 2015 from antenatal clinics at Mount Sinai Hospital, Toronto, Canada...
May 11, 2018: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/29745250/genetic-differentiation-in-a-sample-from-northern-mexico-city-detected-by-hla-system-analysis-impact-in-the-study-of-population-immunogenetics
#18
Eva D Juárez Cortés, Miguel A Contreras Sieck, Agustín J Arriaga Perea, Rosa M Macías Medrano, Anaí Balbuena Jaime, Paola Everardo Martínez, Joaquín Zúñiga, Víctor Acuña Alonzo, Julio Granados, Rodrigo Barquera
The major histocompatibility complex is directly involved in the immune response, and thus the genes coding for its proteins are useful markers for the study of genetic diversity, susceptibility to disease (autoimmunity and infections), transplant medicine, and pharmacogenetics, among others. The polymorphism of the system also allows researchers to use it as a proxy for population genetics analysis, such as genetic admixture and genetic structure. In order to determine the immunogenetic characteristics of a sample from the northern part of Mexico City and to use them to analyze the genetic differentiation from other admixed populations, including those from previous studies of Mexico City population, we analyzed molecular typing results of donors and patients from the Histocompatibility Laboratory of the Central Blood Bank of the Centro Médico Nacional La Raza selected according to their geographic origin...
July 2017: Human Biology
https://www.readbyqxmd.com/read/29740880/fundamental-supply-of-skin-blood-flow-in-the-chinese-han-population-measurements-by-a-full-field-laser-perfusion-imager
#19
W Fei, S Xu, J Ma, W Zhai, S Cheng, Y Chang, X Wang, J Gao, H Tang, S Yang, X Zhang
BACKGROUND: Skin blood flow is believed to link with many diseases, and shows a significant heterogeneity. There are several papers on basal cutaneous microcirculation perfusion in different races, while the data in Chinese is vacant. OBJECTIVE: The aim was to establish the database of absolute fundamental supply of skin blood flow in the Chinese Han population. METHODS: With a full-field laser perfusion imager (FLPI), the skin blood flow can be quantified...
May 8, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29737201/effects-of-cryopreservation-duration-on-the-outcome-of-single-unit-cord-blood-transplantation
#20
Tang-Her Jaing, Shih-Hsiang Chen, Yu-Chuan Wen, Tsung-Yen Chang, Ya-Chun Yang, Pei-Kwei Tsay
Cryopreservation is widely used in umbilical cord blood (UCB) banking, yet its impact on progenitor cell function remains largely unaddressed. It is unknown whether long-term cryopreservation affects UCB transplantation outcomes. Herein, we evaluated the impact of UCB age on clinical outcomes and investigated the effect of cryopreservation duration of UCB on hematopoietic potency in 91 patients receiving single cord blood transplantations. UCB cryopreservation duration was 0.7 to 13.4 y. The most common indication of transplant was thalassemia (48%)...
January 1, 2018: Cell Transplantation
keyword
keyword
64709
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"