keyword
MENU ▼
Read by QxMD icon Read
search

pre—hospital

keyword
https://www.readbyqxmd.com/read/28231611/leg-vascular-and-skeletal-muscle-mitochondrial-adaptations-to-aerobic-high-intensity-exercise-training-are-enhanced-in-the-early-postmenopausal-phase
#1
Michael Nyberg, Jon Egelund, Camilla M Mandrup, Caroline B Andersen, Karen M B E Hansen, Ida-Marie F Hergel, Nicholai Valbak-Andersen, Ruth Frikke-Schmidt, Bente Stallknecht, Jens Bangsbo, Ylva Hellsten
Exercise training leads to favourable adaptations within skeletal muscle; however, this effect of exercise training may be blunted in postmenopausal women due to the loss of oestrogens. Furthermore, postmenopausal women may have an impaired vascular response to acute exercise. We examined the haemodynamic response to acute exercise in matched pre- and postmenopausal women before and after 12 weeks of aerobic high intensity exercise training. Twenty premenopausal and 16 early postmenopausal (3.1 ± 0.5 [mean ± SEM] years after final menstrual period) women only separated by 4 (50 ± 0 versus 54 ± 1) years of age were included...
February 23, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28231555/edge-preserving-denoising-for-intra-operative-cone-beam-ct-in-endovascular-aneurysm-repair
#2
Yi Liu, Miguel Castro, Mathieu Lederlin, Huazhong Shu, Adrien Kaladji, Pascal Haigron
C-arm cone-beam computed tomography (CBCT) acquisition during endovascular aneurysm repair (EVAR) is an emergent technology with more and more applications. It offers real time imaging with a stationary patient and provides 3-D information to achieve guidance of intervention. However, there is growing concern on the overall radiation doses delivered to patients all along the endovascular management due to pre-, intra-, and post-operative X-ray imaging. Manufactures may have their low dose protocols to realize reduction of radiation dose, but CBCT with a low dose protocol has too many artifacts, particularly streak artifacts, and decreased contrast-to-noise ratio (CNR)...
January 30, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28231548/spatiotemporal-exposome-dynamics-of-soil-lead-and-children-s-blood-lead-pre-and-ten-years-post-hurricane-katrina-lead-and-other-metals-on-public-and-private-properties-in-the-city-of-new-orleans-louisiana-u-s-a
#3
Howard W Mielke, Christopher R Gonzales, Eric T Powell, Paul W Mielke
BACKGROUND: Anthropogenic re-distribution of lead (Pb) principally through its use in gasoline additives and lead-based paints have transformed the urban exposome. This unique study tracks urban-scale soil Pb (SPb) and blood Pb (BPb) responses of children living in public and private communities in New Orleans before and ten years after Hurricane Katrina (29 August 2005). OBJECTIVES: To compare and evaluate associations of pre- and ten years post-Katrina SPb and children's BPb on public and private residential census tracts in the core and outer areas of New Orleans, and to examine correlations between SPb and nine other soil metals...
February 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28231538/biochars-with-excellent-pb-ii-adsorption-property-produced-from-fresh-and-dehydrated-banana-peels-via-hydrothermal-carbonization
#4
Nan Zhou, Honggang Chen, Junting Xi, Denghui Yao, Zhi Zhou, Yun Tian, Xiangyang Lu
Fresh and dehydrated banana peels were used as biomass feedstock to produce highly effective sorbent biochars through a facile one-step hydrothermal carbonization approach with 20%vol phosphoric acid as the reaction medium. The elemental ratio of oxygen content of the two as-prepared biochars were about 20%, and the FT-IR analysis confirmed the existence of abundant surface functional groups such as hydroxyl and carboxyl which greatly enhanced the adsorption performance. The sorbents showed excellent lead clarification capability of 359mg·g(-1) and 193mg·g(-1) for dehydrated and fresh banana peels based biochars, respectively...
February 12, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28231501/hsp70-expression-in-biomphalaria-glabrata-snails-exposed-to-cadmium
#5
Rebeca da Silva Cantinha, Sueli Ivone Borrely, Nancy Oguiura, Carlos Alberto de Bragança Pereira, Marcela M Rigolon, Eliana Nakano
In this study, the effects of the heavy metal cadmium on the stress protein HSP70 are investigated in freshwater mollusks Biomphalaria glabrata. Adult snails were exposed for 96h to CdCl2 at concentrations ranging from 0.09 to 0.7mgL(-1) (LC50/96h=0.34 (0.30-0.37). Time and concentration-dependent increases in the expression of HSP70 were observed at sub-lethal levels in the immunoblotting assay. Further, an increased survival to a lethal heat shock was observed in animals pre-exposed to a nonlethal concentration of cadmium, evidencing the induction of acquired tolerance...
February 20, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28231477/effects-of-tdcs-on-motor-learning-and-memory-formation-a-consensus-and-critical-position-paper
#6
REVIEW
Ethan R Buch, Emiliano Santarnecchi, Andrea Antal, Jan Born, Pablo A Celnik, Joseph Classen, Christian Gerloff, Mark Hallett, Friedhelm C Hummel, Michael A Nitsche, Alvaro Pascual-Leone, Walter J Paulus, Janine Reis, Edwin M Robertson, John C Rothwell, Marco Sandrini, Heidi M Schambra, Eric M Wassermann, Ulf Ziemann, Leonardo G Cohen
Motor skills are required for activities of daily living. Transcranial direct current stimulation (tDCS) applied in association with motor skill learning has been investigated as a tool for enhancing training effects in health and disease. Here, we review the published literature investigating whether tDCS can facilitate the acquisition, retention or adaptation of motor skills. Work in multiple laboratories is underway to develop a mechanistic understanding of tDCS effects on different forms of learning and to optimize stimulation protocols...
January 29, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28231431/enhancing-adoptive-cell-therapy-of-cancer-through-targeted-delivery-of-small-molecule-immunomodulators-to-internalizing-or-non-internalizing-receptors
#7
Yiran Zheng, Li Tang, Llian Mabardi, Sudha Kumari, Darrell J Irvine
Adoptive cell therapy (ACT) has achieved striking efficacy in B-cell leukemias, but less success treating other cancers, in part due to the rapid loss of ACT T-cell effector function in vivo due to immunosuppression in solid tumors. Transforming growth factor-β (TGF-β) signaling is an important mechanism of immune suppression in the tumor microenvironment, but systemic inhibition of TGF-β is toxic. Here we evaluated the potential of targeting a small molecule inhibitor of TGF-β to ACT T-cells using PEGylated immunoliposomes...
February 23, 2017: ACS Nano
https://www.readbyqxmd.com/read/28231405/three-dimensional-printing-of-x-ray-computed-tomography-datasets-with-multiple-materials-using-open-source-data-processing
#8
Ian M Sander, Matthew T McGoldrick, My N Helms, Aislinn Betts, Anthony van Avermaete, Elizabeth Owers, Evan Doney, Taimi Liepert, Glen Niebur, Douglas Liepert, W Matthew Leevy
Advances in three-dimensional (3D) printing allow for digital files to be turned into a "printed" physical product. For example, complex anatomical models derived from clinical or pre-clinical X-ray computed tomography (CT) data of patients or research specimens can be constructed using various printable materials. Although 3D printing has the potential to advance learning, many academic programs have been slow to adopt its use in the classroom despite increased availability of the equipment and digital databases already established for educational use...
February 23, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28231395/functional-connectivity-in-amygdalar-sensory-pre-motor-networks-at-rest-new-evidence-from-the-human-connectome-project
#9
Nicola Toschi, Andrea Duggento, Luca Passamonti
The word "e-motion" derives from the Latin word "ex-moveo" which literally means "moving away from something / somebody". Emotions are thus fundamental to prime action and goal-directed behavior with obvious implications for individual's survival. However, the brain mechanisms underlying the interactions between emotional and motor cortical systems remain poorly understood. A recent diffusion tensor imaging study in humans has reported the existence of direct anatomical connections between the amygdala and sensory/(pre)motor cortices, corroborating an initial observation in animal research...
February 23, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28231380/perioperative-medications-for-preventing-temporarily-increased-intraocular-pressure-after-laser-trabeculoplasty
#10
REVIEW
Linda Zhang, Jennifer S Weizer, David C Musch
BACKGROUND: Glaucoma is the international leading cause of irreversible blindness. Intraocular pressure (IOP) is the only currently known modifiable risk factor; it can be reduced by medications, incisional surgery, or laser trabeculoplasty (LTP). LTP reduces IOP by 25% to 30% from baseline, but early acute IOP elevation after LTP is a common adverse effect. Most of these IOP elevations are transient, but temporarily elevated IOP may cause further optic nerve damage, worsening of glaucoma requiring additional therapy, and permanent vision loss...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28231365/alteration-of-serum-levels-of-inflammatory-cytokines-and-polysomnographic-indices-after-uvulopalatal-flap-surgery-in-obstructive-sleep-apnea
#11
Murad Mutlu, Erkan Vuralkan, Istemihan Akin, Hikmet Firat, Sadik Ardic, Sevgi Akaydin, Ece Miser
The aim of the current study was to compare the changes in polysomnographic indices and serum levels of C-reactive protein (CRP), cystatin C, tumor necrosis factor-α (TNF-α), and intercellular adhesion molecule-1 (ICAM-1) in patients with obstructive sleep apnea (OSA) who were treated surgically via a uvulopalatal flap (UPF) technique. Twenty-five patients (14 men, 11 women), average age 46.2 ± 9.3 years, who underwent UPF surgery were included in this study. Serum biochemical analyses and polysomnographic examinations were performed before and 6 months after the surgery...
February 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28231330/the-effects-of-exogenous-hormones-on-rooting-process-and-the-activities-of-key-enzymes-of-malus-hupehensis-stem-cuttings
#12
Wangxiang Zhang, Junjun Fan, Qianqian Tan, Mingming Zhao, Ting Zhou, Fuliang Cao
Malus hupehensis is an excellent Malus rootstock species, known for its strong adverse-resistance and apomixes. In the present study, stem cuttings of M. hupehensis were treated with three types of exogenous hormones, including indole acetic acid (IAA), naphthalene acetic acid (NAA), or green growth regulator (GGR). The effects and mechanisms of exogenous hormone treatment and antioxidant enzyme activity on adventitious root formation were investigated. The results showed that the apparent morphology of the adventitious root had four stages, including root pre-emergence stage (S0), early stage of root formation (S1), massive root formation stage (S2), and later stage of root formation (S3)...
2017: PloS One
https://www.readbyqxmd.com/read/28231310/breastfeeding-and-the-risk-of-respiratory-tract-infections-after-infancy-the-generation-r-study
#13
Ilse Tromp, Jessica Kiefte-de Jong, Hein Raat, Vincent Jaddoe, Oscar Franco, Albert Hofman, Johan de Jongste, Henriëtte Moll
BACKGROUND: The protection of breastfeeding against respiratory tract infections in the first year of life has often been suggested. Few studies examined the effect of breastfeeding on respiratory tract infections after infancy. OBJECTIVE: To examine the association between breastfeeding with lower respiratory tract infections (LRTI) and upper respiratory tract infections (URTI) after infancy up to 4 years of age (n = 5322). METHODS: This study was embedded in The Generation R study, a Dutch population-based prospective cohort study from fetal life until young adulthood...
2017: PloS One
https://www.readbyqxmd.com/read/28231303/greeklex-2-a-comprehensive-lexical-database-with-part-of-speech-syllabic-phonological-and-stress-information
#14
Antonios Kyparissiadis, Walter J B van Heuven, Nicola J Pitchford, Timothy Ledgeway
Databases containing lexical properties on any given orthography are crucial for psycholinguistic research. In the last ten years, a number of lexical databases have been developed for Greek. However, these lack important part-of-speech information. Furthermore, the need for alternative procedures for calculating syllabic measurements and stress information, as well as combination of several metrics to investigate linguistic properties of the Greek language are highlighted. To address these issues, we present a new extensive lexical database of Modern Greek (GreekLex 2) with part-of-speech information for each word and accurate syllabification and orthographic information predictive of stress, as well as several measurements of word similarity and phonetic information...
2017: PloS One
https://www.readbyqxmd.com/read/28231283/rapid-evolution-of-distinct-helicobacter-pylori-subpopulations-in-the-americas
#15
Kaisa Thorell, Koji Yahara, Elvire Berthenet, Daniel J Lawson, Jane Mikhail, Ikuko Kato, Alfonso Mendez, Cosmeri Rizzato, María Mercedes Bravo, Rumiko Suzuki, Yoshio Yamaoka, Javier Torres, Samuel K Sheppard, Daniel Falush
For the last 500 years, the Americas have been a melting pot both for genetically diverse humans and for the pathogenic and commensal organisms associated with them. One such organism is the stomach-dwelling bacterium Helicobacter pylori, which is highly prevalent in Latin America where it is a major current public health challenge because of its strong association with gastric cancer. By analyzing the genome sequence of H. pylori isolated in North, Central and South America, we found evidence for admixture between H...
February 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28231281/the-intron-in-centromeric-noncoding-rna-facilitates-rnai-mediated-formation-of-heterochromatin
#16
Masatoshi Mutazono, Misato Morita, Chihiro Tsukahara, Madoka Chinen, Shiori Nishioka, Tatsuhiro Yumikake, Kohei Dohke, Misuzu Sakamoto, Takashi Ideue, Jun-Ichi Nakayama, Kojiro Ishii, Tokio Tani
In fission yeast, the formation of centromeric heterochromatin is induced through the RNA interference (RNAi)-mediated pathway. Some pre-mRNA splicing mutants (prp) exhibit defective formation of centromeric heterochromatin, suggesting that splicing factors play roles in the formation of heterochromatin, or alternatively that the defect is caused by impaired splicing of pre-mRNAs encoding RNAi factors. Herein, we demonstrate that the splicing factor spPrp16p is enriched at the centromere, and associates with Cid12p (a factor in the RNAi pathway) and the intron-containing dg ncRNA...
February 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28231277/comparison-of-cross-sectional-hiv-incidence-assay-results-from-dried-blood-spots-and-plasma
#17
Katherine E Schlusser, Christopher Pilcher, Esper G Kallas, Breno R Santos, Steven G Deeks, Shelley Facente, Sheila M Keating, Michael P Busch, Gary Murphy, Alex Welte, Thomas Quinn, Susan H Eshleman, Oliver Laeyendecker
BACKGROUND: Assays have been developed for cross-sectional HIV incidence estimation using plasma samples. Large scale surveillance programs are planned using dried blood spot (DBS) specimens for incidence assessment. However, limited information exists on the performance of HIV cross-sectional incidence assays using DBS. METHODS: The assays evaluated were: Maxim HIV-1 Limiting Antigen Avidity EIA (LAg-Avidity), Sedia HIV-1 BED-Capture EIA (BED-CEIA), and CDC modified BioRad HIV-1/2 Plus O Avidity-based Assay (CDC-BioRad Avidity) using pre-determined cutoff values...
2017: PloS One
https://www.readbyqxmd.com/read/28231250/corticospinal-excitability-measurements-using-transcranial-magnetic-stimulation-are-valid-with-intramuscular-electromyography
#18
Rebekah L S Summers, Mo Chen, Teresa J Kimberley
OBJECTIVES: Muscular targets that are deep or inaccessible to surface electromyography (sEMG) require intrinsic recording using fine-wire electromyography (fEMG). It is unknown if fEMG validly record cortically evoked muscle responses compared to sEMG. The purpose of this investigation was to establish the validity and agreement of fEMG compared to sEMG to quantify typical transcranial magnetic stimulation (TMS) measures pre and post repetitive TMS (rTMS). The hypotheses were that fEMG would demonstrate excellent validity and agreement compared with sEMG...
2017: PloS One
https://www.readbyqxmd.com/read/28231249/low-host-specificity-and-abundance-of-frugivorous-lepidoptera-in-the-lowland-rain-forests-of-papua-new-guinea
#19
Katerina Sam, Richard Ctvrtecka, Scott E Miller, Margaret E Rosati, Kenneth Molem, Kipiro Damas, Bradley Gewa, Vojtech Novotny
We studied a community of frugivorous Lepidoptera in the lowland rainforest of Papua New Guinea. Rearing revealed 122 species represented by 1,720 individuals from 326 woody plant species. Only fruits from 52% (171) of the plant species sampled were attacked. On average, Lepidoptera were reared from 1 in 89 fruits and a kilogram of fruit was attacked by 1.01 individuals. Host specificity of Lepidoptera was notably low: 69% (33) of species attacked plants from >1 family, 8% (4) fed on single family, 6% (3) on single genus and 17% (8) were monophagous...
2017: PloS One
https://www.readbyqxmd.com/read/28231247/favipiravir-pharmacokinetics-in-ebola-infected-patients-of-the-jiki-trial-reveals-concentrations-lower-than-targeted
#20
Thi Huyen Tram Nguyen, Jérémie Guedj, Xavier Anglaret, Cédric Laouénan, Vincent Madelain, Anne-Marie Taburet, Sylvain Baize, Daouda Sissoko, Boris Pastorino, Anne Rodallec, Géraldine Piorkowski, Sara Carazo, Mamoudou N Conde, Jean-Luc Gala, Joseph Akoi Bore, Caroline Carbonnelle, Frédéric Jacquot, Hervé Raoul, Denis Malvy, Xavier de Lamballerie, France Mentré
BACKGROUND: In 2014-2015, we assessed favipiravir tolerance and efficacy in patients with Ebola virus (EBOV) disease (EVD) in Guinea (JIKI trial). Because the drug had never been used before for this indication and that high concentrations of the drugs were needed to achieve antiviral efficacy against EBOV, a pharmacokinetic model had been used to propose relevant dosing regimen. Here we report the favipiravir plasma concentrations that were achieved in participants in the JIKI trial and put them in perspective with the model-based targeted concentrations...
February 23, 2017: PLoS Neglected Tropical Diseases
keyword
keyword
64707
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"