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Kevin C Dietrich
BACKGROUND: Central serous chorioretinopathy (CSC) is usually a self-limiting condition; however, there is potential for recurrence and permanent visual defects. Aviation demands perfect vision to minimize risk to pilots and aircraft. Consequently, this ailment disqualifies pilots and pilots to be. CASE REPORT: A fully trained fighter pilot with 1260 h in fighter airframes has been contending with central serous chorioretinopathy in the right eye over the course of 3 yr...
2016: Aerospace Medicine and Human Performance
Emin Özmert, Sibel Demirel, Özge Yanık, Figen Batıoğlu
Purpose. To compare the efficacy and safety of subthreshold micropulse yellow wavelength laser (SMYL) and low-fluence photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSC). Methods. Thirty-three eyes of 30 patients with chronic CSC received either PDT (18 eyes) or SMYL (15 eyes) therapy. Best corrected visual acuity (BCVA), subretinal fluid (SRF) height, and central macular thickness (CMT) were evaluated at the baseline visit and one, three, six, nine, and 12 months after the therapy...
2016: Journal of Ophthalmology
Nisreen S Ezuddin, Nicole L Lanza, Christina Y Weng
No abstract text is available yet for this article.
2016: International Ophthalmology Clinics
P Scholz, L Altay, S Fauser
PurposeTo compare the short-term treatment outcome of the 577 nm subthreshold micropulse laser (SML) and half-dose photodynamic therapy (PDT) in patients with chronic central serous chorioretinopathy (cCSC) and persistent subretinal fluid (SRF).MethodsThis retrospective study included 100 eyes of 100 consecutive patients who were treated with the 577 nm SML (Supra Scan, Quantel Medical) (n=42) or half-dose PDT (n=58) for cCSC. The treatment was applied at the leakage sites in the fluorescein and indocyanine green angiography...
July 8, 2016: Eye
Zhouyue Li, Yanping Song, Xiao Chen, Zhongshan Chen, Qin Ding
Many clinical trials have demonstrated the effectiveness of subthreshold phototherapy with no visible damage in retinal vascular diseases, such as diabetic retinopathy. We aimed primarily to investigate the effect of subthreshold diode micropulse laser (SDM) treatment on mouse retinal pigmented epithelium (RPE) cells. The expression of angiogenesis-modulating cytokines in response to SDM was also explored. The least toxic laser dose was selected by measuring cell viability with MTT assay and 5 % duty cycle (DC) was chosen for use in further experiments...
November 2015: Cell Biochemistry and Biophysics
Jeffrey K Luttrull
PURPOSE: To review the results of low-intensity/high-density subthreshold micropulse laser (SDM) for treatment of central serous chorioretinopathy. METHOD: The records of all patients treated in a retinal subspecialty practice with SDM for central serous chorioretinopathy were reviewed. RESULTS: Eleven consecutive eyes of 11 patients treated between October 2011 and April 2014 were identified for study, 9 men and 2 women, aged 30 to 55 (mean = 46)...
September 2016: Retina
Guohai Chen, Radouil Tzekov, Wensheng Li, Fangzheng Jiang, Sihong Mao, Yuhua Tong
PURPOSE: To evaluate the relative efficacy of subthreshold micropulse diode laser versus conventional laser photocoagulation for the treatment of diabetic macular edema. METHODS: A comprehensive literature search was conducted to find relevant randomized controlled trials (RCTs). Efficacy estimates were determined by comparing weighted mean differences of the mean change of best-corrected visual acuity and central macular thickness from baseline. RESULTS: Six RCTs were selected for this meta-analysis, including 398 eyes (203 eyes in the subthreshold micropulse diode laser group and 195 eyes in the conventional laser group)...
April 18, 2016: Retina
Hemal Mehta, Mark C Gillies, Samantha Fraser-Bell
This review provides a perspective on published and ongoing clinical trials of vascular endothelial growth factor inhibitors (anti-VEGF agents) combined with laser therapy for diabetic macular oedema (DMO). Although there was little short-term benefit in combining prompt macular laser with anti-VEGF therapy for centre-involving DMO in the Diabetic Retinopathy Clinical Research Network (DRCRnet) Protocol I study, deferred macular laser was still required in over 40% of study eyes in DRCRnet Protocol T. Macular laser was applied in more than 30% of eyes with centre-involving DMO receiving ranibizumab in the RISE and RIDE studies...
May 2016: Clinical & Experimental Ophthalmology
Hilary S Brader, Lucy H Y Young
The subthreshold diode micropulse laser is a form of non-damaging thermal laser therapy which has shown efficacy in multiple retinal conditions. The purpose of this article is to review the use of subthreshold diode micropulse laser as an emerging treatment modality for the treatment of retinal disease. The proposed mechanisms of action, safety, efficacy, recommended laser treatment parameters, and clinical applications for which the use of subthreshold diode micropulse laser has been studied will be reviewed...
2016: Seminars in Ophthalmology
Georgios Labiris, Aspasia Toli, Damaskini Polychroni, Maria Gkika, Dimitrios Angelonias, Vassilios P Kozobolis
A systematic review of the recent literature regarding the implementation of the liquefaction in cataract surgery and its short-term and long-term outcomes in various parameters that affect the quality of patients' life, including visual rehabilitation and possible complications was performed based on the PubMed, Medline, Nature and the American Academy of Ophthalmology databases in November 2013 and data from 14 comparative studies were included in this narrative review. Liquefaction is an innovative technology for cataract extraction that uses micropulses of balanced salt solution to liquefy the lens nucleus...
2016: International Journal of Ophthalmology
Young Gun Park, Young-Jung Roh
Diabetic retinopathy (DR) is a severe sight-threatening complication of diabetes mellitus. Retinal laser photocoagulation, antivascular endothelial growth factors, steroid therapy, and pars plana vitrectomy are now used extensively to treat advanced stages of diabetic retinopathy. Currently, diagnostic devices like ultrawide field fundus fluorescein angiography and the improvement of optical coherence tomography have provided quicker and more precise diagnosis of early diabetic retinopathy. Thus, treatment protocols have been modified accordingly...
2016: Journal of Diabetes Research
Gokhan Gulkilik, Mahmut Odabasi, Sevil Karaman Erdur, Mustafa Ozsutcu, Mustafa Eliacik, Goktug Demirci, Mehmet Selim Kocabora
No abstract text is available yet for this article.
January 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Bradley S Henriksen, Gareth Gardiner, Kevin Garff, Isha Gupta, Brian C Stagg, Brian Zaugg, Jeff H Pettey, William R Barlow, Randall J Olson
OBJECTIVE: To compare thermal profiles of new transversal ultrasound power modulation to torsional ultrasound in an artificial chamber and cadaver eye. DESIGN: Laboratory investigation. METHODS: John A. Moran Eye Center Laboratories, University of Utah, Salt Lake City, Utah, was the study setting. Temperature increase after 30 seconds was measured at the needle midshaft in an artificial chamber and at maximal friction point in a cadaver eye...
February 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Jeffrey K Luttrull, Benjamin W L Margolis
PURPOSE: To review the results of retinal function testing in eyes undergoing panmacular subthreshold diode micropulse laser (SDM) prophylaxis for chronic progressive retinal disease. METHODS: The records of all patients undergoing prophylactic panmacular SDM for high-risk age-related macular degeneration (AMD) and inherited photoreceptor degenerations (IRDs) examined by pattern electroretinography (PERG), automated microperimetry (AMP), and Central Vision Analyzer (CVA) testing before and after treatment were reviewed...
January 1, 2016: Investigative Ophthalmology & Visual Science
Sarah Kuchar, Marlene R Moster, Courtney B Reamer, Michael Waisbourd
Glaucoma is the leading cause of irreversible blindness worldwide. The goal of this study was to describe our experience with the novel micropulse transscleral cyclophotocoagulation (MP-TSCPC; IRIDEX IQ810 Laser Systems, CA) in patients with advanced glaucoma. Patients with advanced glaucoma who underwent MP-TSCPC were included in our study. Laser settings were 2000 mW of 810 nm infrared diode laser set on micropulse delivery mode. The laser was delivered over 360° for 100-240 s. The duty cycle was 31.3 %, which translated to 0...
February 2016: Lasers in Medical Science
Mahsa Salehi, Adam S Wenick, Hua Andrew Law, Jennifer R Evans, Peter Gehlbach
BACKGROUND: Central serous chorioretinopathy (CSC) is characterized by serous detachment of the neural retina with dysfunction of the choroid and retinal pigment epithelium (RPE). The effects on the retina are usually self limited, although some people are left with irreversible vision loss due to progressive and permanent photoreceptor damage or RPE atrophy. There have been a variety of interventions used in CSC, including, but not limited to, laser treatment, photodynamic therapy (PDT), and intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents...
2015: Cochrane Database of Systematic Reviews
Ahmed Hosni Abd Elhamid
PURPOSE: To report the efficacy and safety of micropulse 577 nm yellow laser in the treatment of nonresolving central serous chorioretinopathy (CSC) cases. PATIENTS AND METHODS: The study included 15 eyes with nonresolving CSC lasting more than 3 months. All the patients were subjected to complete ophthalmic examination, in addition to contrast sensitivity measurement, fundus fluorescein angiography, and optical coherence tomography. All eyes were subjected to 577 nm subthreshold micropulse laser treatment, using the IQ 577 device, and followed up after 4 weeks, 2 months, 3 months, and 6 months...
2015: Clinical Ophthalmology
Jacky W Y Lee, Gordon S K Yau, Doris W F Yick, Can Y F Yuen
The aim of the study was to investigate the safety and efficacy of using MLT in the treatment of open-angle glaucoma (OAG).This prospective cohort included subjects ≥18 years of age with OAG, defined as the open angle on gonioscopy with glaucomatous optic neuropathy evident from optical coherence tomography. Subjects with IOP < 21 mm Hg were classified as normal tension glaucoma and those with IOP ≥21 mm Hg were classified as primary open-angle glaucoma. Those with angle closure, secondary glaucoma, prior laser trabeculoplasty, use of systemic IOP-lowering medications, corneal pathologies, follow-up <6 months, recent intraocular surgery, or only 1 functional eye were excluded...
December 2015: Medicine (Baltimore)
Cyrus F Abari, Xinzhao Chu, R Michael Hardesty, Jakob Mann
This paper shows an efficient adaptation of a polarization diversity optical front-end, commonly used in high-speed fiber-optic communications, in a coherent Doppler lidar (CDL). The adopted architecture can be employed in a modified transceiver design for an all-fiber micropulsed coherent Doppler wind lidar where the performance limits of such systems are pushed beyond the conventionally available wind CDLs. As a result, either a longer measurement range, crucial in clear-air environments with low concentration of aerosols, or a shorter integration time (resulting in a faster scanning) can be achieved...
October 20, 2015: Applied Optics
Gianni Virgili, Manuele Michelessi, Maurizio B Parodi, Daniela Bacherini, Jennifer R Evans
BACKGROUND: Drusen are amorphous yellowish deposits beneath the sensory retina. People with drusen, particularly large drusen, are at higher risk of developing age-related macular degeneration (AMD). The most common complication in AMD is choroidal neovascularisation (CNV), the growth of new blood vessels in the centre of the macula. The risk of CNV is higher among people who are already affected by CNV in one eye.It has been observed clinically that laser photocoagulation of drusen leads to their disappearance and may prevent the occurrence of advanced disease (CNV or geographic atrophy) associated with visual loss...
2015: Cochrane Database of Systematic Reviews
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