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Daniel Su, Jean-Pierre Hubschman
The role of retinal photocoagulation as a first line therapy for various retinal pathologies has decreased with the introduction of anti-vascular endothelial growth factor therapy. However, retinal laser therapy remains an important treatment modality, especially with the emergence of micropulse subthreshold treatment and the integration of newer technology such as augmented reality and semi-automated delivery. This review summarizes current evidence for micropulse laser as a treatment modality and discusses the role of new technology such as augmented reality in the future of laser therapy...
February 9, 2017: Ophthalmology and Therapy
K Akaoka, I McKendry, J Saxton, P W Cottle
Transport of coal by train through residential neighborhoods in Metro Vancouver, British Columbia, Canada may increase the possibility of exposure to particulate matter at different size ranges, with concomitant potential negative health impacts. This pilot study identifies and quantifies train impacts on particulate matter (PM) concentrations at a single location. Field work was conducted during August and September 2014, with the attributes of a subset of passing trains confirmed visually, and the majority of passages identified with audio data...
April 2017: Environmental Pollution
Behzad Amoozgar, Eileen N Phan, Shan C Lin, Ying Han
PURPOSE OF REVIEW: There are currently various options available for glaucoma treatment procedures ranging from laser to penetrating to nonpenetrating surgeries. Innovations in glaucoma surgical therapeutics include features such as external application, focused tissue effects, and minimal manipulation as these factors all help lower the risk of side-effects in addition to increasing the success rate of the treatment. Traditional diode laser transscleral cyclophotocoagulation (TSCPC) is invasive and destructive...
March 2017: Current Opinion in Ophthalmology
John Ware, Eric A Kort, Phil DeCola, Riley Duren
Atmospheric observations of greenhouse gases provide essential information on sources and sinks of these key atmospheric constituents. To quantify fluxes from atmospheric observations, representation of transport-especially vertical mixing-is a necessity and often a source of error. We report on remotely sensed profiles of vertical aerosol distribution taken over a 2 year period in Pasadena, California. Using an automated analysis system, we estimate daytime mixing layer depth, achieving high confidence in the afternoon maximum on 51% of days with profiles from a Sigma Space Mini Micropulse LiDAR (MiniMPL) and on 36% of days with a Vaisala CL51 ceilometer...
August 27, 2016: Journal of Geophysical Research. Atmospheres: JGR
Farhad Fazel, Majid Bagheri, Khodayar Golabchi, Hamidreza Jahanbani Ardakani
PURPOSE: The aim of the present study was to investigate the effect of subthreshold diode laser micropulse (SDM) in comparison with conventional laser photocoagulation in the treatment of the diabetic macular edema (DME). METHODS: Sixty-eight eyes from 68 patients with clinically significant DME were divided randomly into two equal groups. In the first group, SDM photocoagulation was employed, while conventional laser photocoagulation was performed on the eyes of the second group...
December 2016: Journal of Current Ophthalmology
Kevin C Dietrich
BACKGROUND: Central serous chorioretinopathy (CSC) is usually a self-limiting condition; however, there is potential for recurrence and permanent visual defects. Aviation demands perfect vision to minimize risk to pilots and aircraft. Consequently, this ailment disqualifies pilots and pilots to be. CASE REPORT: A fully trained fighter pilot with 1260 h in fighter airframes has been contending with central serous chorioretinopathy in the right eye over the course of 3 yr...
2016: Aerospace Medicine and Human Performance
Emin Özmert, Sibel Demirel, Özge Yanık, Figen Batıoğlu
Purpose. To compare the efficacy and safety of subthreshold micropulse yellow wavelength laser (SMYL) and low-fluence photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSC). Methods. Thirty-three eyes of 30 patients with chronic CSC received either PDT (18 eyes) or SMYL (15 eyes) therapy. Best corrected visual acuity (BCVA), subretinal fluid (SRF) height, and central macular thickness (CMT) were evaluated at the baseline visit and one, three, six, nine, and 12 months after the therapy...
2016: Journal of Ophthalmology
Nisreen S Ezuddin, Nicole L Lanza, Christina Y Weng
No abstract text is available yet for this article.
2016: International Ophthalmology Clinics
P Scholz, L Altay, S Fauser
PurposeTo compare the short-term treatment outcome of the 577 nm subthreshold micropulse laser (SML) and half-dose photodynamic therapy (PDT) in patients with chronic central serous chorioretinopathy (cCSC) and persistent subretinal fluid (SRF).MethodsThis retrospective study included 100 eyes of 100 consecutive patients who were treated with the 577 nm SML (Supra Scan, Quantel Medical) (n=42) or half-dose PDT (n=58) for cCSC. The treatment was applied at the leakage sites in the fluorescein and indocyanine green angiography...
October 2016: Eye
Zhouyue Li, Yanping Song, Xiao Chen, Zhongshan Chen, Qin Ding
Many clinical trials have demonstrated the effectiveness of subthreshold phototherapy with no visible damage in retinal vascular diseases, such as diabetic retinopathy. We aimed primarily to investigate the effect of subthreshold diode micropulse laser (SDM) treatment on mouse retinal pigmented epithelium (RPE) cells. The expression of angiogenesis-modulating cytokines in response to SDM was also explored. The least toxic laser dose was selected by measuring cell viability with MTT assay and 5 % duty cycle (DC) was chosen for use in further experiments...
November 2015: Cell Biochemistry and Biophysics
Jeffrey K Luttrull
PURPOSE: To review the results of low-intensity/high-density subthreshold micropulse laser (SDM) for treatment of central serous chorioretinopathy. METHOD: The records of all patients treated in a retinal subspecialty practice with SDM for central serous chorioretinopathy were reviewed. RESULTS: Eleven consecutive eyes of 11 patients treated between October 2011 and April 2014 were identified for study, 9 men and 2 women, aged 30 to 55 (mean = 46)...
September 2016: Retina
Guohai Chen, Radouil Tzekov, Wensheng Li, Fangzheng Jiang, Sihong Mao, Yuhua Tong
PURPOSE: To evaluate the relative efficacy of subthreshold micropulse diode laser versus conventional laser photocoagulation for the treatment of diabetic macular edema. METHODS: A comprehensive literature search was conducted to find relevant randomized controlled trials (RCTs). Efficacy estimates were determined by comparing weighted mean differences of the mean change of best-corrected visual acuity and central macular thickness from baseline. RESULTS: Six RCTs were selected for this meta-analysis, including 398 eyes (203 eyes in the subthreshold micropulse diode laser group and 195 eyes in the conventional laser group)...
November 2016: Retina
Hemal Mehta, Mark C Gillies, Samantha Fraser-Bell
This review provides a perspective on published and ongoing clinical trials of vascular endothelial growth factor inhibitors (anti-VEGF agents) combined with laser therapy for diabetic macular oedema (DMO). Although there was little short-term benefit in combining prompt macular laser with anti-VEGF therapy for centre-involving DMO in the Diabetic Retinopathy Clinical Research Network (DRCRnet) Protocol I study, deferred macular laser was still required in over 40% of study eyes in DRCRnet Protocol T. Macular laser was applied in more than 30% of eyes with centre-involving DMO receiving ranibizumab in the RISE and RIDE studies...
May 2016: Clinical & Experimental Ophthalmology
Hilary S Brader, Lucy H Y Young
The subthreshold diode micropulse laser is a form of non-damaging thermal laser therapy which has shown efficacy in multiple retinal conditions. The purpose of this article is to review the use of subthreshold diode micropulse laser as an emerging treatment modality for the treatment of retinal disease. The proposed mechanisms of action, safety, efficacy, recommended laser treatment parameters, and clinical applications for which the use of subthreshold diode micropulse laser has been studied will be reviewed...
2016: Seminars in Ophthalmology
Georgios Labiris, Aspasia Toli, Damaskini Polychroni, Maria Gkika, Dimitrios Angelonias, Vassilios P Kozobolis
A systematic review of the recent literature regarding the implementation of the liquefaction in cataract surgery and its short-term and long-term outcomes in various parameters that affect the quality of patients' life, including visual rehabilitation and possible complications was performed based on the PubMed, Medline, Nature and the American Academy of Ophthalmology databases in November 2013 and data from 14 comparative studies were included in this narrative review. Liquefaction is an innovative technology for cataract extraction that uses micropulses of balanced salt solution to liquefy the lens nucleus...
2016: International Journal of Ophthalmology
Young Gun Park, Young-Jung Roh
Diabetic retinopathy (DR) is a severe sight-threatening complication of diabetes mellitus. Retinal laser photocoagulation, antivascular endothelial growth factors, steroid therapy, and pars plana vitrectomy are now used extensively to treat advanced stages of diabetic retinopathy. Currently, diagnostic devices like ultrawide field fundus fluorescein angiography and the improvement of optical coherence tomography have provided quicker and more precise diagnosis of early diabetic retinopathy. Thus, treatment protocols have been modified accordingly...
2016: Journal of Diabetes Research
Gokhan Gulkilik, Mahmut Odabasi, Sevil Karaman Erdur, Mustafa Ozsutcu, Mustafa Eliacik, Goktug Demirci, Mehmet Selim Kocabora
No abstract text is available yet for this article.
January 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Bradley S Henriksen, Gareth Gardiner, Kevin Garff, Isha Gupta, Brian C Stagg, Brian Zaugg, Jeff H Pettey, William R Barlow, Randall J Olson
OBJECTIVE: To compare thermal profiles of new transversal ultrasound power modulation to torsional ultrasound in an artificial chamber and cadaver eye. DESIGN: Laboratory investigation. METHODS: John A. Moran Eye Center Laboratories, University of Utah, Salt Lake City, Utah, was the study setting. Temperature increase after 30 seconds was measured at the needle midshaft in an artificial chamber and at maximal friction point in a cadaver eye...
February 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
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