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bronchopneumonia

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https://www.readbyqxmd.com/read/28591169/exposure-of-bighorn-sheep-to-domestic-goats-colonized-with-mycoplasma-ovipneumoniae-induces-sub-lethal-pneumonia
#1
Thomas E Besser, E Frances Cassirer, Kathleen A Potter, William J Foreyt
BACKGROUND: Bronchopneumonia is a population limiting disease of bighorn sheep (Ovis canadensis) that has been associated with contact with domestic Caprinae. The disease is polymicrobial but is initiated by Mycoplasma ovipneumoniae, which is commonly carried by both domestic sheep (O. aries) and goats (Capra aegagrus hircus). However, while previous bighorn sheep comingling studies with domestic sheep have resulted in nearly 100% pneumonia mortality, only sporadic occurrence of fatal pneumonia was reported from previous comingling studies with domestic goats...
2017: PloS One
https://www.readbyqxmd.com/read/28542233/is-survival-improved-by-the-use-of-niv-and-peg-in-amyotrophic-lateral-sclerosis-als-a-post-mortem-study-of-80-als-patients
#2
Christian Burkhardt, Christoph Neuwirth, Andreas Sommacal, Peter M Andersen, Markus Weber
BACKGROUND: Non-invasive ventilation (NIV) and percutaneous gastrostomy (PEG) are guideline-recommended interventions for symptom management in amyotrophic lateral sclerosis (ALS). Their effect on survival is controversial and the impact on causes of death is unknown. OBJECTIVE: To investigate the effect of NIV and PEG on survival and causes of death in ALS patients. METHODS: Eighty deceased ALS patients underwent a complete post mortem analysis for causes of death between 2003 and 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28536684/gastrointestinal-cytomegalovirus-disease-in-a-patient-with-pemphigus-vulgaris-treated-with-corticosteroid-and-mycophenolate-mofetil
#3
Luiza Barbosa Oliveira, Celina Wakisaka Maruta, Denise Miyamoto, Fernanda Aburesi Salvadori, Claudia Giuli Santi, Valeria Aoki, Amaro Nunes Duarte-Neto
Pemphigus vulgaris is an autoimmune disease characterized by the formation of suprabasal intra-epidermal blisters on the skin and mucosal surfaces. Infectious diseases are the main cause of death in patients with pemphigus due to the disrupture of the physiological skin barrier, immune dysregulation, and the use of immunosuppressive medications leaving the patient prone to acquire opportunistic infections. We report the case of a 67-year-old woman diagnosed with pemphigus vulgaris, who was irregularly taking prednisone and mycophenolate mofetil...
January 2017: Autopsy & case reports
https://www.readbyqxmd.com/read/28515580/infectious-pneumonia-in-the-immunocompetent-host-what-the-radiologist-should-know
#4
Rohini G Ghasi, Sunil K Bajaj
Lung infections are an important cause of morbidity and mortality, particularly because of the rising antimicrobial resistance. According to the clinical setting, they can be categorized as community-acquired pneumonia and hospital-acquired pneumonia. Radiological patterns of lung infections are lobar consolidation, bronchopneumonia, interstitial pattern, and nodular pattern. In addition, typical imaging features of several infections serve as "red flag signs" in reaching a diagnosis or altering the management...
January 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28494709/hypervirulent-klebsiella-pneumoniae-in-california-sea-lions-zalophus-californianus-pathologic-findings-in-natural-infections
#5
Mauricio Seguel, Nicole L Gottdenker, Kathleen Colegrove, Shawn Johnson, Carsten Struve, Elizabeth W Howerth
Tissues of stranded California sea lions ( Zalophus californianus) naturally infected with a hyperviruluent strain of Klebsiella pneumoniae were examined by histopathology and immunohistochemistry against the K. pneumoniae K2 capsular antigen. In 7 of 8 animals, there was severe purulent bronchopneumonia, sometimes complicated by fibrinonecrotizing pleuritis with pyothorax. In affected areas of lung, large numbers of degenerate neutrophils and macrophages were admixed with rare large extracellular and intracellular gram-negative bacilli surrounded by a prominent capsule...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28494707/histologic-and-ultrastructural-findings-in-dogs-with-chronic-respiratory-disease-suspected-of-ciliary-dyskinesia
#6
Ileana C Miranda, Jennifer L Granick, Anibal G Armién
Mucociliary clearance is a main defense mechanism of the respiratory tract, which can be inherently impaired in primary ciliary dyskinesia (PCD) or reversibly altered in secondary ciliary dyskinesia (SCD). Limited diagnostic test availability likely leads to misdiagnosis or underdiagnosis of PCD in animals. This study evaluated the light and transmission electron microscopy (TEM) changes in the respiratory mucosa of 15 dogs with chronic respiratory disease suspected of PCD. Necropsy was performed in 1 case and 2 dogs were used as negative controls...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28482756/bronchopneumonia-associated-with-mannheimia-granulomatis-infection-in-a-belgian-hare-lepus-europaeus
#7
Ann P Britton, Tony Redford, Erin Zabek, Ken R Sojonky, Andrea P Scouras, Danielle Lewis, Tomy Joseph
Mannheimia granulomatis was first isolated from pneumonic European hares in the 1980s and has since been reported sporadically in pneumonic Swedish roe deer and Australian cattle. Although the pneumonic lesions caused by M. haemolytica in livestock have been extensively studied and reported, little is published with regard to the pneumonic lesions associated with M. granulomatis infection in any species. We describe the histopathology of purulent bronchopneumonia associated with M. granulomatis in a Belgian hare ( Lepus europaeus) resident in British Columbia, Canada, and compare the lesions with those caused by M...
May 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28450986/-major-sickle-cell-syndromes-and-infections-associated-with-this-condition-in-children-in-burkina-faso
#8
Sonia Douamba, Kisito Nagalo, Laure Tamini, Ismaël Traoré, Madibèlè Kam, Fla Kouéta, Diarra Yé
INTRODUCTION: This study aims to investigate infections in children with major sickle cell syndrome. METHODS: We conducted a monocentric descriptive retrospective hospital study in Ouagadougou, Burkina Faso, over a ten-year period. All children with major sickle cell syndrome (homozygous SS and double heterozygous SC, SDPunjab, Sβ thalassemic, SOArab and SE) hospitalized for microbiologically confirmed infections were enrolled in the study. RESULTS: One hundred and thirty-three patients met our inclusion criteria...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28421633/efficacy-of-tulathromycin-for-the-treatment-of-foals-with-mild-to-moderate-bronchopneumonia
#9
D Rutenberg, M Venner, S Giguère
BACKGROUND: There is conflicting data regarding the efficacy of tulathromycin for the treatment of foals with bronchopneumonia. HYPOTHESES: Tulathromycin is effective for the treatment of bronchopneumonia in foals and noninferior to the combination of azithromycin and rifampin. ANIMALS: A total of 240 foals on a farm endemic for infections caused by Rhodococcus equi. METHODS: In a controlled, randomized, and double-blinded clinical trial, foals with ultrasonographic pulmonary lesions (abscess score 10-15 cm) were allocated to 3 groups: 1-tulathromycin IM q 7 days (n = 80); 2-azithromycin-rifampin, orally q24h (n = 80); or 3-untreated controls (n = 80)...
May 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28355107/pathology-of-aging-in-nod-scid-gamma-female-mice
#10
Sara F Santagostino, Rodolfo J Ricart Arbona, Melissa A Nashat, Julie R White, Sebastien Monette
In the past decade, NOD.Cg- Prkdc(scid) Il2rg(tm1Wjl)/SzJ (NSG, NOD scid gamma) mice have become a model of choice in several areas of biomedical research; however, comprehensive data on their spontaneous age-related pathology are not currently available in the literature. The prevalence of spontaneous morbidity affecting aged NSG female breeders enrolled in a parasitology study was documented with classification of neoplastic and non-neoplastic (inflammatory, metabolic, degenerative) lesions. Malignant mammary neoplasms were most commonly diagnosed, often accompanied by pulmonary metastases, while a low frequency of lymphoma and histiocytic sarcoma was documented...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28284621/identification-of-a-novel-host-specific-igg-protease-in-streptococcus-phocae-subsp-phocae
#11
Viktoria Rungelrath, Jan Christian Wohlsein, Ursula Siebert, Jeffrey Stott, Ellen Prenger-Berninghoff, Ulrich von Pawel-Rammingen, Peter Valentin-Weigand, Christoph G Baums, Jana Seele
Streptococcus (S.) phocae subsp. phocae causes bronchopneumonia and septicemia in a variety of marine mammals. Especially in harbor seals infected with phocine distemper virus it plays an important role as an opportunistic pathogen. This study was initiated by the detection of IgG cleavage products in Western blot analysis after incubation of bacterial supernatant with harbor seal serum. Hence, the objectives of this study were the identification and characterization of a secreted IgG cleaving protease in S...
March 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28197285/percutaneous-intervention-of-a-persistent-left-superior-vena-cava-draining-into-left-pulmonary-vein-and-coarctation-of-the-aorta
#12
Saad Al Bugami, Mohammed Althobaiti, Tarek Momenah, Jamilah Alrahimi, Wael Al Kashkari
We describe a 54-year-old male with history of type II DM, hypertension and dyslipidemia during admission for bronchopneumonia discovered to have coarctation of the aorta and a persistent left superior vena cava (PLSVC) draining into the left atrium through the left superior pulmonary vein. The latter was thought to contribute to a transient ischemic attack and an episode of chest pain resulting in ST-segment elevation in the inferior leads. He was treated with coarctation stenting and percutaneous exclusion of the PLSVC with a vascular plug...
August 2016: Cardiology Research
https://www.readbyqxmd.com/read/28187318/effect-of-maternal-cells-transferred-with-colostrum-on-the-health-of-neonate-calves
#13
Sylvia Marquart Fontes Novo, Juliana Fraça Dos Reis Costa, Camila Costa Baccili, Natália Meirelles Sobreira, Bruno Toledo Silva, Pamella Lorenci de Oliveira, David John Hurley, Viviani Gomes
The objective of this research was to evaluate the influence of cells from colostrum on the health of neonate calves. Animals were distributed in 2 groups: COL+ (n=9) which received fresh colostrum from their own damns; and COL- (n=10) which received frozen colostrums from donors. Heifers were assessed before colostrum intake - D0; D2; D7; D14; D21 and D28. Heifers were monitored by clinical examination, hematological profile and serum iron. COL- had a higher diarrhea intensity score (typically 3) on D7. Moreover, a single case each of bronchopneumonia and navel inflammation were observed in COL- calves...
January 27, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28166820/case-report-clinical-and-postmortem-findings-in-four-cows-with-rib-fracture
#14
Ueli Braun, Sonja Warislohner, Udo Hetzel, Karl Nuss
BACKGROUND: Published reports of rib fractures in adult cattle are limited to the occurrence of chronic rib swellings caused by calluses, which are unremarkable from a clinical standpoint, whereas studies identifying clinical signs of rib fractures were not found in a literature search. This report describes the clinical and postmortem findings in four cows with rib fractures. CASE PRESENTATION: The 13th rib was fractured in three cows and the 11th rib in the remaining cow; three fractures were on the right and one on the left side...
February 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28166707/isolation-and-partial-characterization-of-streptococcus-suis-from-clinical-cases-in-cattle
#15
Ogi Okwumabua, Hanna Peterson, Hui-Min Hsu, Phil Bochsler, Melissa Behr
Sixteen isolates of gram-positive, coccoid bacteria were obtained from clinical cases of diverse conditions in cattle and identified as Streptococcus suis using 16S ribosomal DNA gene sequencing and other bacterial identification methods. None of the isolates could be assigned to any of the known S. suis capsular types. Virulence-associated gene profiling that targeted muramidase-released protein, extracellular protein factor, suilysin, 89-kb pathogenicity island, and arginine deiminase ( arcA) genes were negative except for 1 isolate that was arcA positive...
March 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28139956/bacterial-microbiota-in-harbor-seals-phoca-vitulina-from-the-north-sea-of-schleswig-holstein-germany-around-the-time-of-morbillivirus-and-influenza-epidemics
#16
Ursula Siebert, Marion Rademaker, Sophie A Ulrich, Peter Wohlsein, Katrin Ronnenberg, Ellen Prenger-Berninghoff
We present microbiologic findings in harbor seal (phoca; Phoca vitulina ) carcasses collected from the North Sea of Schleswig-Holstein, Germany, 1996-2014, and interpret results in relation to potential variations caused by phocine distemper virus and influenza A virus mass mortalities. We conducted microbiologic investigations on 2,124 tissue samples from lung, liver, kidney, spleen, intestine, and mesenteric lymph nodes from 549 dead harbor seals of the German North Sea. A large variety of bacteria, including potentially pathogenic species such as Bordetella bronchiseptica , Brucella spp...
April 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28131371/two-years-of-surveillance-of-influenza-a-virus-infection-in-a-swine-herd-results-of-virological-serological-and-pathological-studies
#17
Javier Cappuccio, Marina Dibarbora, Inés Lozada, Alejandra Quiroga, Valeria Olivera, Marta Dángelo, Estefanía Pérez, Hernán Barrales, Carlos Perfumo, Ariel Pereda, Daniel R Pérez
Swine farms provide a dynamic environment for the evolution of influenza A viruses (IAVs). The present report shows the results of a surveillance effort of IAV infection in one commercial swine farm in Argentina. Two cross-sectional serological and virological studies (n=480) were carried out in 2011 and 2012. Virus shedding was detected in nasal samples from pigs from ages 7, 21 and 42-days old. More than 90% of sows and gilts but less than 40% of 21-days old piglets had antibodies against IAV. In addition, IAV was detected in 8/17 nasal swabs and 10/15 lung samples taken from necropsied pigs...
February 2017: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/28099077/disease-complexity-in-a-declining-alaskan-muskox-ovibos-moschatus-population
#18
Josephine A Afema, Kimberlee B Beckmen, Stephen M Arthur, Kathy Burek Huntington, Jonna A K Mazet
The muskox ( Ovibos moschatus ) population inhabiting the eastern North Slope (ENS) of Alaska, US declined dramatically during 1999-2006, whereas populations in western Alaska (WA) were stable or increasing. To understand morbidity and mortality factors contributing to the decline, Alaska Department of Fish and Game conducted pathologic investigations of carcasses from 2005 until 2008. Additionally, archived sera from both ENS and WA muskoxen collected during 1984-92, before the documented beginning of the ENS decline; sera collected during 2000, near the beginning of the decline; and contemporary sera (from live capture-release, adult females) collected during 2006, 2007, and 2008 were analyzed to determine whether prevalence of antibody to potential pathogens differed in the two areas or changed over time...
April 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28087464/mitochondrial-reactive-oxygen-species-regulate-fungal-protease-induced-inflammatory-responses
#19
Yun Hee Kim, Seung-Hyo Lee
Epidemiological studies have shown that fungal infections are a main cause of respiratory tract diseases, such as asthma, bronchopneumonia, intoxication, and invasive fungal disease. Fungi such as Aspergillus and Candida species have become increasingly important pathogens as the global climate changes. Accordingly, in this study, we evaluated the toxicological potential of Aspergillus protease in the lower respiratory tract. Exposure of Aspergillus protease to A549 cells induced upregulation of tumor necrosis factor (TNF)-α, monocyte chemoattractant protein (MCP)-1, and intercellular adhesion molecule (ICAM)-1 mRNAs and increased production of interleukin (IL)-8 and MCP-1 protein through enhanced mitochondrial reactive oxygen species (ROS) generation and activation of mitogen-activated protein kinase (MAPK) and activator protein (AP)-1...
March 1, 2017: Toxicology
https://www.readbyqxmd.com/read/28074713/pathogens-patterns-of-pneumonia-and-epidemiologic-risk-factors-associated-with-respiratory-disease-in-recently-weaned-cattle-in-ireland
#20
Gerard M Murray, Simon J More, Dónal Sammin, Mìcheàl J Casey, Máire C McElroy, Rónan G O'Neill, William J Byrne, Bernadette Earley, Tracy A Clegg, Hywel Ball, Colin J Bell, Joseph P Cassidy
We examined the pathogens, morphologic patterns, and risk factors associated with bovine respiratory disease (BRD) in 136 recently weaned cattle ("weanlings"), 6-12 mo of age, that were submitted for postmortem examination to regional veterinary laboratories in Ireland. A standardized sampling protocol included routine microbiologic investigations as well as polymerase chain reaction and immunohistochemistry. Lungs with histologic lesions were categorized into 1 of 5 morphologic patterns of pneumonia. Fibrinosuppurative bronchopneumonia (49%) and interstitial pneumonia (48%) were the morphologic patterns recorded most frequently...
January 2017: Journal of Veterinary Diagnostic Investigation
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