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https://www.readbyqxmd.com/read/29227122/-hamartoma-of-mature-cardiac-myocytes-autopsy-case-report
#1
Šárka Hadravská, Magdaléna Dubová, Markéta Miesbauerová, Petr Mukenšnabl, Ondřej Daum, Alois Mádle, Karel Smetana
Hamartoma of mature cardiac myocytes (HMCM) is a rare benign pseudoneoplastic myocardial lesion. We describe a case of 39-year-old Bulgarian woman living in the Czech Republic, who died because of rupture of anterior communicating artery aneurysm, and severe bronchopneumonia. An incidental finding at the autopsy was a whitish unencapsulated and not sharply demarcated tumor of the left ventricle and adjacent area of interventricular septum, which protruded above the plane of section. Microscopically the tumor consisted of various different forms of disorganized hypertrophic mature cardiac myocytes without vacuolization of cytoplasm, focally in a "herringbone" pattern...
2017: Ceskoslovenská Patologie
https://www.readbyqxmd.com/read/29212461/widespread-enlarged-perivascular-spaces-associated-with-dementia-and-focal-brain-dysfunction-case-report
#2
Daisuke Taniguchi, Hideki Shimura, Masao Watanabe, Nobutaka Hattori, Takao Urabe
BACKGROUND: Enlarged perivascular spaces (PVS) are common magnetic resonance imaging (MRI) findings, whereas widespread enlarged PVS are extremely rare. Although most patients with widespread enlarged PVS remain asymptomatic, some develop neurological dysfunctions; however, it remains unclear whether these are the consequence of widespread enlarged PVS. CASE PRESENTATION: A 64-year-old female patient developed consciousness disturbance, cognitive dysfunctions, fluent aphasia, agraphia, acalculia, and left-right disorientation after suffering from bronchopneumonia...
December 7, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29190684/respiratory-syncytial-and-influenza-viruses-in-children-under-2-years-old-with-severe-acute-respiratory-infection-sari-in-maputo-2015
#3
Mirela Pale, Afonso Nacoto, Almiro Tivane, Neuza Nguenha, Loira Machalele, Félix Gundane, Délcio Muteto, Josina Chilundo, Sandra Mavale, Cynthia Semá-Baltazar, Germano Pires, Orvalho Augusto, Tufária Mussá, Eduardo Gudo
INTRODUCTION: Although respiratory syncytial virus (RSV) and influenza virus (influenza) infections are one of the leading causes of Severe Acute Respiratory Infections (SARI) and death in young children worldwide, little is known about the burden of these pathogens in Mozambique. MATERIAL AND METHODS: From January 2015 to January 2016, nasopharyngeal swabs from 450 children, aged ≤2 years, who had been admitted to the Pediatric Department of the Maputo Central Hospital (HCM) in Mozambique, suffering with SARI were enrolled and tested for influenza and RSV using a real-time PCR assay...
2017: PloS One
https://www.readbyqxmd.com/read/29168366/normal-sweat-chloride-test-does-not-rule-out-cystic-fibrosis
#4
Abdurrahman Erdem Başaran, Nimet Karataş-Torun, İbrahim Cemal Maslak, Ayşen Bingöl, Özgül M Alper
Başaran AE, Karataş-Torun N, Maslak İC, Bingöl A, Alper ÖM. Normal sweat chloride test does not rule out cystic fibrosis. Turk J Pediatr 2017; 59: 68-70. A 5-month-old patient presented with complaints of fever and cough. He was hospitalized with the diagnosis of bronchopneumonia and pseudo-Bartter's syndrome. Patient was further investigated for diagnosis of cystic fibrosis. The chloride (Cl) level in sweat was determined within the normal range (25.1 mmol/L, 20.3 mmol/L). CFTR (Cystic Fibrosis Transmembrane Regulator gene; NM_000492...
2017: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/29157308/characterization-of-the-upper-and-lower-respiratory-tract-microbiota-in-piedmontese-calves
#5
Isabella Nicola, Francesco Cerutti, Elena Grego, Iride Bertone, Paola Gianella, Antonio D'Angelo, Simone Peletto, Claudio Bellino
BACKGROUND: The microbiota of the bovine upper respiratory tract has been recently characterized, but no data for the lower respiratory tract are available. A major health problem in bovine medicine is infectious bronchopneumonia, the most common respiratory syndrome affecting cattle. With this study, we used 16S rRNA gene sequencing to characterize and compare the microbial community composition of the upper and lower respiratory tracts in calves. RESULTS: The microbiota of the upper (nasal swab [NS]) and the lower (trans-tracheal aspiration [TTA]) respiratory tracts of 19 post-weaned Piedmontese calves with (8/19) and without (11/19) clinical signs of respiratory disease, coming from six different farms, was characterized by 16S rRNA gene metabarcoding...
November 21, 2017: Microbiome
https://www.readbyqxmd.com/read/29149111/-bilateral-bronchopneumonia-due-to-rothia-mucilaginosa
#6
B De Escalante Yangüela, A Gracia Gutiérrez, B C Gracia Tello, V A Alastrué Del Castaño, E Bueno Juana, S Algárate Cajo
Rothia mucilaginosa (R. mucilaginosa), formerly named Stomatococcus mucilaginosus, is a facultatively anaerobic, encapsulated gram-positive coccus, which forms part of the normal oropharyngeal and is rarely considered to be a pathogen in immunocompetent patients, although it can produce, on rare occasions, serious infections like bacteremia, endocarditis and respiratory infections; such as pneumonia, pleural empyema or superinfection of bronchiectasis. We present the case of a 74-year-old male diagnosed with right basal pneumonia of torpid evolution with a poor initial response to different antibiotics, with clinical and radiological worsening and the appearance of bilateral bronchopneumonia with pseudonodular images...
November 17, 2017: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/29139241/porcine-respiratory-disease-complex-after-the-introduction-of-h1n1-2009-influenza-virus-in-brazil
#7
R R Rech, D Gava, M C Silva, L T Fernandes, V Haach, J R Ciacci-Zanella, R Schaefer
From 2009 to 2015, 74 lungs from suckling (6.8%), nursing (70.3%), fattening (20.3%) pigs and pregnant sows (2.7%) with respiratory signs from pig farms in Southern Brazil were submitted to a diagnostic laboratory for necropsy and/or histologic examination and screening for respiratory agents by RT-qPCR, immunohistochemistry (IHC), virus isolation (VI) and subtyping for influenza A virus (IAV), IHC and nested PCR for Mycoplasma hyopneumoniae (Mhyo), PCR for porcine circovirus 2 (PCV2), RT-qPCR for porcine reproductive and respiratory syndrome virus (PRRSV) and bacterial culture...
November 14, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29114129/case-report-severe-and-progressive-bronchopneumonia-by-aelurostrongylus-abstrusus-in-an-adopted-stray-cat-from-portugal
#8
Carla Soares, Manuela Cardoso, Ana Mestre, Paolo Emidio Crisi
The cat lungworm Aelurostrongylus abstrusus is the most common respiratory parasite of cats. This nematode has a worldwide distribution and is considered an emerging pathogen. Respiratory signs overlap with those of other pathologies, and some agents which co-exist in the same animal may concur in the clinical scenario. Nonetheless, feline verminous bronchopneumonia is underestimated by practitioners and is not commonly included in differential diagnosis in routine practice. The present report describes the clinical presentation of a 6-month old stray cat from central Portugal, which developed respiratory distress...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29105570/molecular-survey-of-infectious-agents-associated-with-bovine-respiratory-disease-in-a-beef-cattle-feedlot-in-southern-brazil
#9
Selwyn A Headley, Werner Okano, Luciana C Balbo, Rogério A Marcasso, Thalita E Oliveira, Alice F Alfieri, Luiz C Negri Filho, Mariana Z Michelazzo, Silvio C Rodrigues, Anderson L Baptista, João Paulo E Saut, Amauri A Alfieri
We investigated the occurrence of infectious pathogens during an outbreak of bovine respiratory disease (BRD) in a beef cattle feedlot in southern Brazil that has a high risk of developing BRD. Nasopharyngeal swabs were randomly collected from steers ( n = 23) and assessed for the presence of infectious agents of BRD by PCR and/or RT-PCR assays. These included: Histophilus somni, Mannheimia haemolytica, Pasteurella multocida, Mycoplasma bovis, bovine respiratory syncytial virus (BRSV), bovine coronavirus (BCoV), bovine viral diarrhea virus (BVDV), bovine alphaherpesvirus 1 (BoHV-1), and bovine parainfluenza virus 3 (BPIV-3)...
November 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29091330/multicentre-observational-study-of-gastrointestinal-recovery-after-elective-colorectal-surgery
#10
(no author information available yet)
INTRODUCTION: Postoperative ileus (POI) is characterised by delayed gastrointestinal recovery and is common after colorectal surgery. Numerous strategies to optimise POI have been proposed but its management remains unclear. This study aimed to characterise the duration and management of gastrointestinal recovery in patients undergoing elective colorectal surgery. METHODS: A snapshot, prospective, observational study was undertaken between November 2016 and January 2017 at 10 regional hospitals in the United Kingdom...
November 1, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29077699/pneumococcal-conjugate-vaccine-and-pneumonia-prevention-in-children-with-congenital-heart-disease
#11
Fortino Solórzano-Santos, Lilia Espinoza-García, Glorinella Aguilar-Martínez, Luisa Beirana-Palencia, Gabriela Echániz-Avilés, Guadalupe Miranda-Novales
BACKGROUND: A successful strategy to prevent Streptococcus pneumoniae infections is the administration of pneumococcal conjugate vaccines (PCVs). OBJECTIVE: To analyze the effectiveness of the 7- and 13-valent PCV for the prevention of all-cause pneumonia. MATERIALS AND METHODS: A retrospective cohort of children younger than 5 years of age, with congenital heart disease (CHD) and different vaccination schedules, was analyzed. History of vaccination was confirmed with verifiable records...
September 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29065887/computed-tomography-of-the-thorax-in-rabbits-a-prospective-study-in-ten-clinically-healthy-new-zealand-white-rabbits
#12
Désirée Müllhaupt, Sandra Wenger, Patrick Kircher, Nadja Pfammatter, Jean-Michel Hatt, Stefanie Ohlerth
BACKGROUND: Literature investigating the normal cross-sectional anatomy of rabbits with computed tomography (CT) is sparse and incomplete. The purpose of the present study was to investigate the normal thoracic structures, in particular the cranial thorax, with CT angiography in 10 clinically healthy New Zealand White (NZW) rabbits. RESULTS: Absolute and relative measurements of the trachea, heart, thoracic caudal vena cava and aorta, right and left principal bronchi, right and left caudal lobar bronchi and the accompanying branches of the right and left pulmonary artery and vein, right and left lung volume and lung density were taken...
October 24, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29028839/interaction-of-the-human-respiratory-syncytial-virus-matrix-protein-with-cellular-adaptor-protein-complex-3-plays-a-critical-role-in-trafficking
#13
Casey Ward, Maciej Maselko, Christopher Lupfer, Meagan Prescott, Manoj K Pastey
Human Respiratory Syncytial Virus (HRSV) is a leading cause of bronchopneumonia in infants and the elderly. To date, knowledge of viral and host protein interactions within HRSV is limited and are critical areas of research. Here, we show that HRSV Matrix (M) protein interacts with the cellular adaptor protein complex 3 specifically via its medium subunit (AP-3Mu3A). This novel protein-protein interaction was first detected via yeast-two hybrid screen and was further confirmed in a mammalian system by immunofluorescence colocalization and co-immunoprecipitation...
2017: PloS One
https://www.readbyqxmd.com/read/28990950/a-rare-complication-of-chronic-granulomatous-disease-in-a-child-constrictive-aspergillus-pericarditis
#14
Emrah Şişli, Yasemin Özdemir Şahan, Mehmet Fatih Ayık, Deniz Nart, Yüksel Atay
A 3-year-old girl with the diagnosis of chronic granulomatous disease (CGD) was hospitalized for bronchopneumonia and congestive heart failure. Her medical history included methylprednisolone medication for autoimmune gastric outlet obstruction. Computed tomography revealed pneumonic infiltrations and pericardial thickening. A pulsed-wave Doppler recording revealed E/A >1. During a pericardiectomy, multiple islands of thick, firm-walled, fibrinous exudate-containing, small abscess formations were observed...
October 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28990687/phrenicoabdominal-venotomy-for-tumor-thrombectomy-in-dogs-with-adrenal-neoplasia-and-suspected-vena-caval-invasion
#15
Philipp D Mayhew, William T N Culp, Ingrid M Balsa, Allison L Zwingenberger
OBJECTIVE: To describe a technique for tumor thrombectomy by phrenicoabdominal venotomy in dogs with adrenal neoplasia and suspected caval invasion and to report complications and outcomes associated with the procedure. STUDY DESIGN: Retrospective case series. ANIMALS: Eight client-owned dogs with invasive adrenal tumors. METHODS: Medical records of dogs diagnosed with adrenal tumors with extension of thrombus into the phrenicoabdominal vein (PAV) and vena cava were reviewed...
October 9, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28982020/streptococcus-phocae-in-marine-mammals-of-northeastern-pacific-and-arctic-canada-a-retrospective-analysis-of-85-postmortem-investigations
#16
Nicole D Taurisano, Brian P Butler, Diana Stone, Harry Hariharan, Paul J Fields, Hugh W Ferguson, Martin Haulena, Paul Cotrell, Ole Nielsen, Stephen Raverty
Streptococcus phocae is a pathogen of marine mammals, although its pathogenicity remains poorly understood. Recovery of this bacterium from asymptomatic carriers suggests that it is an opportunistic pathogen. We investigated the role of S. phocae in naturally occurring disease and its significance as a pathogen based on postmortem investigations. Between 2007 and 2012, 1,696 whole carcasses, tissue samples, or both were submitted from the northeastern Pacific and Arctic Canada for diagnostic testing. Streptococcus phocae was cultured from phocids (n=66), otariids (n=12), harbor porpoises (Phocoena phocoena; n=5), and sea otters (Enhydra lutris; n=2)...
October 5, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28956483/association-of-the-severity-of-lung-lesions-with-carcass-and-meat-quality-in-slaughter-pigs
#17
Nedjeljko Karabasil, Nikola Čobanović, Ivana Vučićević, Silvana Stajković, Zsolt Becskei, Petra Forgách, Sanja Aleksić-Kovačević
The aim of this study was to determine the association of lung lesions with carcass and meat quality traits in slaughter pigs and to describe the main morphological features associated with lung lesions. Macroscopic lesions on the lungs were detected in 67.09% of a total of 79 pigs examined. Histopathological examination revealed that acute and chronic interstitial pneumonia represented the commonest changes, detected in 26.67% and 33.33% of the cases, respectively. Bronchopneumonia was found in 33.33% of the cases...
September 2017: Acta Veterinaria Hungarica
https://www.readbyqxmd.com/read/28935008/coccidioidomycosis-in-an-indoor-housed-rhesus-macaque-macaca-mulatta
#18
Mila C Kundu, Michael A Ringenberg, Denise L d'Epagnier, Heather L Haag, Sean Maguire
Coccidioides spp. are saprophytic, dimorphic fungi that are endemic to arid climates, are capable of infecting many species, and result in diverse clinical presentations. An indoor-housed laboratory rhesus macaque presented with weight loss and decreased activity and appetite. During the diagnostic evaluation, a bronchiolar-alveolar pattern in the cranial lung lobes, consistent with bronchopneumonia, was noted on radiographs. Given the poor prognosis, the macaque was euthanized. Confirming the radiographic assessment, gross necropsy findings included multifocal to coalescing areas of consolidation in the right and left cranial lung lobes...
October 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28905977/-incidence-and-mortality-of-common-neonatal-diseases-in-the-foal-during-the-first-10-days-post-natum-in-a-veterinary-hospital
#19
Martin Graßl, Tina Ulrich, Axel Wehrend
OBJECTIVE: The aim of this study was to present the incidence and lethality of diseases in foals during the first 10 days following birth by analyzing patient data. MATERIAL AND METHODS: Over a period of 6 years, patient data from 393 foals, that had been presented within the first 10 days after birth in a hospital, were evaluated. The number of diseases, the sex of the affected foals and the lethality were documented. RESULTS: A total of 28 diseases were diagnosed, with systemic inflammatory response syndrome (SIRS), meconium impaction and bronchopneumonia being the most frequent diagnoses...
September 13, 2017: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/28831754/comparative-therapeutic-effect-of-steroidal-and-non-steroidal-anti-inflammatory-drugs-on-pro-inflammatory-cytokine-production-in-water-buffalo-calves-bubalus-bubalis-naturally-infected-with-bronchopneumonia-a-randomized-clinical-trial
#20
Mohamed Abdo Rizk, Motamed Elsayed Mahmoud, Shimaa Abd El-Salam El-Sayed, Doaa Salman
In the current study, we compared the therapeutic effects of a non-steroidal and a steroidal anti-inflammatory drug on the production of pro-inflammatory cytokines, interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-12p40 (IL-12p40), interferon gamma (IFNγ), and tumor necrosis factor alpha (TNF-α) in the blood of water buffalo (Bubalus bubalis) calves naturally infected by bronchopneumonia. Twenty-seven buffalo calves (7 ± 2-month-old, 163 ± 12 kg) reared in smallholder farms in El-Dakahlia province in Egypt were identified to have bronchopneumonia and randomly allocated into three equal groups...
December 2017: Tropical Animal Health and Production
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