Benjamin Bar-Oz, Corinna Weber-Schoendorfer, Maya Berlin, Maurizio Clementi, Elena Di Gianantonio, Loes de Vries, Marco De Santis, Paul Merlob, Bracha Stahl, Giorgio Eleftheriou, Eva Maňáková, Lucie Hubičková-Heringová, Ilan Youngster, Matitiahu Berkovitch
BACKGROUND: Macrolides are a group of commonly prescribed antibiotics. There is some doubt surrounding the use of the newer macrolides in pregnancy. OBJECTIVE: The present study aimed to compare outcomes of pregnancies exposed to the new macrolides clarithromycin, azithromycin and roxithromycin with non-teratogenic preparations. METHODS: In this prospective, multinational, multicentre, controlled, observational study, information was obtained either from pregnant women or their healthcare professionals who contacted their local teratogen information services in Italy, Israel, the Czech Republic, the Netherlands and Germany seeking information after exposure to macrolides...
July 1, 2012: Drug Safety: An International Journal of Medical Toxicology and Drug Experience