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https://www.readbyqxmd.com/read/28743563/high-spatial-and-temporal-resolution-anthropogenic-heat-discharge-estimation-in-los-angeles-county-california
#1
Yuanfan Zheng, Qihao Weng
Anthropogenic heat flux (Qf), which originates through energy consumption from buildings, industrial plants, vehicle exhausts, and human metabolism releases, is an important component in the urban Surface Energy Balance (SEB) system, and is key to understanding of many urban environmental issues. The present study provided a hybrid Qf modeling approach, which combined the inventory and GIS approach to create a 365-day hourly Qf profile at 120 m spatial resolution in Los Angeles County, California, USA. Qf was estimated by separate calculation of heat release from buildings, traffics, and human metabolism, respectively...
July 22, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28736763/immunologic-effects-of-maraviroc-in-hiv-infected-patients-with-severe-cd4-lymphopenia-starting-antiretroviral-therapy-a-sub-study-of-the-cadiris-trial
#2
Pablo F Belaunzarán-Zamudio, Livio Azzoni, David H Canaday, Yanink N Caro-Vega, Brian Clagget, Mohammed S Rassool, Benigno Rodriguez, Ian Sanne, Irini Sereti, Juan G Sierra-Madero, Michael M Lederman
BACKGROUND: We aimed to describe the mechanisms of immunological recovery and the effects of blocking CCR5 in patients starting ART with advanced HIV-infection. METHODS: This was a sub-study of a 48 week double-blind, clinical trial where patients starting ART with CD4+ cell counts <100 cells/uL were randomized to receive maraviroc or a placebo. CD4+ and CD8+ cell maturation phenotypes, expression of PD-1 and CCR5, and activation indices were measured at weeks 0, 4, 12, 24, and 48...
2017: Pathogens & Immunity
https://www.readbyqxmd.com/read/28735610/social-emotional-and-behavioral-screening-a-comparison-of-two-measures-and-two-methods-across-informants
#3
Ryan J Kettler, Kelly A Feeney-Kettler, Leah Dembitzer
The current study is a correlational design comparing a multiple-gate social, emotional, and behavioral (SEB) screening system with a single-gate SEB screening system using a common criterion variable. Teachers and parents of 105 preschool students completed the multiple-gate Preschool Behavior Screening System (PBSS; Feeney-Kettler, Kratochwill, & Kettler, 2009) and the single-gate Behavioral and Emotional Screening System (BESS; Kamphaus & Reynolds, 2007). The measures were evaluated using Cronbach's alpha, Pearson correlations with each other, and conditional probability indices to represent accuracy in predicting scores from the Achenbach System for Empirically Based Assessment (ASEBA; Achenbach & Rescorla, 2000)...
October 2017: Journal of School Psychology
https://www.readbyqxmd.com/read/28735055/molecular-analysis-of-virulence-genes-and-the-accessory-gene-regulator-agr-types-among-methicillin-resistant-staphylococcus-aureus-mrsa-strains
#4
Sara Cheraghi, Leyla Pourgholi, Maryam Shafaati, Shirinsadat Hashemi Fesharaki, Arash Jalali, Rahim Nosrati, MohammadAli Boroumand
OBJECTIVES: Methicillin resistant S. aureus (MRSA) strains are a main cause of hospital-acquired infections and are considered as a serious public-health concern. MRSA isolates have plenty of virulence factors, which are the basis for its pathogenicity. The controlling and coordination of the expression of these genes perform by the accessory gene regulator (agr). The aim of this study was to determine the rate of some virulence genes encoding the enterotoxin, exfoliative toxin genes (eta), the adhesin genes and identification of agr specificity groups in MRSA isolates...
July 19, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28729209/clonal-spread-of-methicillin-resistant-staphylococcus-aureus-t6065-cc5-sccmecv-agrii-in-a-libyan-hospital
#5
Monia Khemiri, Ali Akrout Alhusain, Mohamed Salah Abbassi, Houyem El Ghaieb, Sofia Santos Costa, Adriana Belas, Constança Pomba, Salah Hammami
OBJECTIVES: The aim of this study was to characterize 32 MRSA isolates recovered from wound specimens of patients in a Hospital in Tripoli, Libya, during 2013. METHODS: MRSA isolates were characterized by determining their antibiotic susceptibilities, genes encoding antibiotic resistance and virulence factors, the SCCmec class, agr type, spa typing, PFGE and MLST. RESULTS: PFGE and MLST revealed that all isolates were clonal and belonged to the Clonal Complex 5 (CC5)...
July 17, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28727010/effect-of-experimentally-increased-protein-supply-to-postpartum-dairy-cows-on-plasma-protein-synthesis-rumen-tissue-proliferation-and-immune-homeostasis
#6
M Larsen, C M Røntved, P K Theil, M Khatun, C Lauridsen, N B Kristensen
The effect of experimentally increasing the postpartum protein supply on plasma protein synthesis, rumen tissue proliferation, and immune homeostasis was studied using 8 periparturient Holstein cows in a complete randomized design. At calving, cows were assigned to abomasal infusion of water (CTRL) or casein (CAS) in addition to a lactation diet. Casein infusion was gradually decreased from 696 ± 1 g/d at +2 d relative to calving (DRTC) to 212 ± 10 g/d at +29 DRTC to avoid excessive supply. Synthesis rate of plasma proteins was measured at -14, +4, +15, and +29 DRTC by measuring [C]Phe isotopic enrichment in arterial plasma free Phe, total plasma proteins, and albumin after 3, 5, and 7 h of jugular ring[C]Phe infusion...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28720885/two-photon-interference-of-polarization-entangled-photons-in-a-franson-interferometer
#7
Heonoh Kim, Sang Min Lee, Osung Kwon, Han Seb Moon
We present two-photon interference experiments with polarization-entangled photon pairs in a polarization-based Franson-type interferometer. Although the two photons do not meet at a common beamsplitter, a phase-insensitive Hong-Ou-Mandel type two-photon interference peak and dip fringes are observed, resulting from the two-photon interference effect between two indistinguishable two-photon probability amplitudes leading to a coincidence detection. A spatial quantum beating fringe is also measured for nondegenerate photon pairs in the same interferometer, although the two-photon states have no frequency entanglement...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28705503/building-a-bio-based-hydrogel-via-electrostatic-and-host-guest-interactions-for-realizing-dual-controlled-release-mechanism
#8
Shuai Han, Ting Wang, Li Yang, Bin Li
Bio-based hydrogel containing cyclodextrins (CDs) is of a promising polymer material that could display many advantages including wide availability, sustainability, biocompatibility and biodegradability, especially the inherent encapsulation ability with hydrophobic substance. To obtain these, the electrostatic and host-guest interactions were introduced and a hydrogel with three-dimensional double network structures was built. For preparing a spherical biopolymer cage, hydroxyethyl cellulose (HEC) and modified chitosan (HACC) were cross-linked by a one-pot reaction...
July 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28668759/adverse-childhood-experiences-among-youth-reported-to-child-welfare-results-from-the-national-survey-of-child-adolescent-wellbeing
#9
Antonio R Garcia, Meera Gupta, Johanna K P Greeson, Allison Thompson, Christina DeNard
The negative influence of adverse childhood experiences (ACEs) on social, emotional, and behavioral (SEB) outcomes are well documented. However, no research to date has examined the effect of ACEs on SEB outcomes in youth who received mental health services after reporting to the child welfare system. This study's analyses of data from the National Survey of Child and Adolescent Well-Being II revealed that the most prevalent ACEs included hospitalization for a medical condition, neglect, and exposures to domestic and community violence...
June 29, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28666414/comparative-transcriptome-analysis-reveals-different-strategies-for-degradation-of-steam-exploded-sugarcane-bagasse-by-aspergillus-niger-and-trichoderma-reesei
#10
Gustavo Pagotto Borin, Camila Cristina Sanchez, Eliane Silva de Santana, Guilherme Keppe Zanini, Renato Augusto Corrêa Dos Santos, Angélica de Oliveira Pontes, Aline Tieppo de Souza, Roberta Maria Menegaldo Tavares Soares Dal'Mas, Diego Mauricio Riaño-Pachón, Gustavo Henrique Goldman, Juliana Velasco de Castro Oliveira
BACKGROUND: Second generation (2G) ethanol is produced by breaking down lignocellulosic biomass into fermentable sugars. In Brazil, sugarcane bagasse has been proposed as the lignocellulosic residue for this biofuel production. The enzymatic cocktails for the degradation of biomass-derived polysaccharides are mostly produced by fungi, such as Aspergillus niger and Trichoderma reesei. However, it is not yet fully understood how these microorganisms degrade plant biomass. In order to identify transcriptomic changes during steam-exploded bagasse (SEB) breakdown, we conducted a RNA-seq comparative transcriptome profiling of both fungi growing on SEB as carbon source...
June 30, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28648918/acoustic-and-elastic-properties-of-glycerol-in-oil-based-gel-phantoms
#11
Luciana C Cabrelli, Felipe W Grillo, Diego R T Sampaio, Antonio A O Carneiro, Theo Z Pavan
Phantoms are important tools for image quality control and medical training. Many phantom materials have been proposed for ultrasound; most of them use water as the solvent, but these materials have disadvantages such as dehydration and low temporal stability if not properly stored. To overcome these difficulties, copolymer-in-oil gel was proposed as an inert and stable material; however, speed of sound for these materials is still lower than what is described for most biological tissues. Here, we propose the glycerol dispersion in oil-based gels to modify the acoustic and elastic properties of copolymer-in-oil phantoms...
June 22, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28632753/mait-cells-launch-a-rapid-robust-and-distinct-hyperinflammatory-response-to-bacterial-superantigens-and-quickly-acquire-an-anergic-phenotype-that-impedes-their-cognate-antimicrobial-function-defining-a-novel-mechanism-of-superantigen-induced-immunopathology
#12
Christopher R Shaler, Joshua Choi, Patrick T Rudak, Arash Memarnejadian, Peter A Szabo, Mauro E Tun-Abraham, Jamie Rossjohn, Alexandra J Corbett, James McCluskey, John K McCormick, Olivier Lantz, Roberto Hernandez-Alejandro, S M Mansour Haeryfar
Superantigens (SAgs) are potent exotoxins secreted by Staphylococcus aureus and Streptococcus pyogenes. They target a large fraction of T cell pools to set in motion a "cytokine storm" with severe and sometimes life-threatening consequences typically encountered in toxic shock syndrome (TSS). Given the rapidity with which TSS develops, designing timely and truly targeted therapies for this syndrome requires identification of key mediators of the cytokine storm's initial wave. Equally important, early host responses to SAgs can be accompanied or followed by a state of immunosuppression, which in turn jeopardizes the host's ability to combat and clear infections...
June 2017: PLoS Biology
https://www.readbyqxmd.com/read/28593698/associations-between-expressive-and-receptive-language-and-internalizing-and-externalizing-behaviours-in-a-community-based-prospective-study-of-slow-to-talk-toddlers
#13
Laura J Conway, Penny A Levickis, Fiona Mensah, Cristina McKean, Kylie Smith, Sheena Reilly
BACKGROUND: Evidence suggests that language and social, emotional and behavioural (SEB) difficulties are associated in children and adolescents. When these associations emerge and whether they differ by language or SEB difficulty profile is unclear. This knowledge is crucial to guide prevention and intervention programmes for children with language and SEB difficulties. AIMS: To determine whether receptive and expressive language skills are associated with internalizing and externalizing behaviours in slow-to-talk toddlers...
June 8, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28573424/vitamin-d-inhibits-the-staphylococcal-enterotoxin-b-induced-expression-of-tumor-necrosis-factor-in-microglial-cells
#14
Jinggui He, Xiyun Guo, Zhi-Qiang Liu, Ping-Chang Yang, Shaobo Yang
Microglial cells play a crucial role in inflammatory responses in neural tissue. Vitamin D (VitD3) deficiency is associated with the pathogenesis of inflammation. Staphylococcal enterotoxin B (SEB) is a superantigen and can initiate inflammation. This study tests a hypothesis that VitD3 deficiency upregulates the expression of tumor necrosis factor (TNF) in microglial cells. Microglial cells were isolated from the mouse brain. The microglial cells were cultured in the presence or absence of VitD3 or/and SEB...
August 2017: Immunologic Research
https://www.readbyqxmd.com/read/28561911/biofilm-formation-and-virulence-factor-analysis-of-staphylococcus-aureus-isolates-collected-from-ovine-mastitis
#15
E Azara, C Longheu, G Sanna, S Tola
AIMS: To perform a phenotypic and genotypic characterization of 258 Staphylococcus aureus isolates from clinical ovine mastitis and used for the preparation of inactivated autogenous vaccines. METHODS AND RESULTS: The potential for biofilm production was determined by phenotypic test of Congo Red Agar (CRA) and by PCR for the detection of icaA/D genes. Isolates were also screened by PCR for the presence of enterotoxins (sea, seb, sec, sed and see), toxic shock syndrome toxin (tsst), leukotoxins (lukD-E, lukM and lukPV83), haemolysins (hly-β and hly-γ), autolysin (atlA) genes and encoding microbial surface components recognizing adhesive matrix molecules (MSCRAMMs: clfA, clfB, fnbA, fnbB, bbp, cna, eno, fib, epbs, sdrC, sdrD and SdrE)...
May 31, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28555177/changes-in-frequency-and-activation-status-of-major-cd4-t-cell-subsets-after-initiation-of-immunosuppressive-therapy-in-a-patient-with-new-diagnosis-childhood-onset-systemic-lupus-erythematosus
#16
Saimun Singla, Scott E Wenderfer, Eyal Muscal, Anna Carmela P Sagcal-Gironella, Jordan S Orange, George Makedonas
BACKGROUND: Several studies suggest that defects of regulatory T-cells (Tregs) and impaired cellular immunity are secondary to an imbalance between auto-aggressive T-cells and Tregs in lupus patients. Discrepancies in Tregs and effector T-cells (Teff) in active lupus patients are shown to be restored in patients upon receiving immunosuppressive therapy. Therefore, our main aim was to observe frequencies of these CD4(+) T-cell subsets and Tregs/Teff ratio in a new diagnosis of childhood-onset systemic lupus erythematous (cSLE) before and after initiation of therapy...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28535395/a-zinc-chloride-doped-adhesive-facilitates-sealing-at-the-dentin-interface-a-confocal-laser-microscopy-study
#17
Manuel Toledano, Raquel Osorio, Estrella Osorio, Inmaculada Cabello, Manuel Toledano-Osorio, Fátima S Aguilera
The aim of this study was to ascertain the effect of Zn-doping of dental adhesives and mechanical load cycling on the micromorphology of the resin-dentin interdiffusion zone (of sound and caries affected dentin). The investigation considered two different Zn-doped adhesive approaches and evaluated the interface using a doubled dye fluorescent technique and a calcium chelator fluorophore under a confocal laser scanning microscopy. Sound and carious dentin-resin interfaces of unloaded specimens were deficiently resin-hybridized, in general...
May 19, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28525337/molecular-characterization-and-detection-of-enterotoxins-methicillin-resistance-genes-and-antimicrobial-resistance-of-staphylococcus-aureus-from-fish-and-ground-beef
#18
S Arslan, F Özdemir
A total of 120 samples including 40 freshwaterfish(Oncorhynchus mykiss), 40 seawater fish (Sparus aurata) and 40 ground beef samples were examined for the presence of Staphylococcus aureus. The isolates were identified using biochemical tests and a PCR for the species-specific fragment (Sa442) and thermonuclease gene (nucA). The presence of staphylococcal enterotoxin genes (sea, seb, sec, sed and see), toxin genes (eta, etb, tsst), methicillin resistance gene (mecA) and some phenotypic virulence factors was also tested...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28506885/high-proportions-of-staphylococcus-epidermidis-in-dental-caries-harbor-multiple-classes-of-antibiotics-resistance-significantly-increase-inflammatory-interleukins-in-dental-pulps
#19
Darshan Devang Divakar, Muzaheed, Sultan Salem Aldeyab, Sara A Alfawaz, Abdulaziz Abdullah AlKheraif, Aftab Ahmed Khan
Staphylococcus epidermidis is one of most prevalent in dental caries or dental pulp which has the capability of horizontal genetic transfer between different bacterial species in the oropharynx, suggesting that it may evolve with the dissemination of resistant determinants, This study was performed to molecularly characterize and differentiate S. epidermidis isolated from dental caries and healthy individual. Also, two important cytokines in inflammation were assayed caused due to S. epidermidis of health and dental caries sources...
May 12, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28503802/electrospun-polyethersolfone-nanofibrous-membrane-as-novel-platform-for-protein-immobilization-in-microfluidic-systems
#20
Matin Mahmoudifard, Manouchehr Vossoughi, Sara Soudi, Masoud Soleimani
In the present study, the feasibility of electrospun polyethersolfone (PES) nanofibrous membrane as the solid substrate for microfluidic based immunoassays to enhance the density of immobilized antibody on the surface of membrane was assessed. Conversely, the efficacy of antibody immobilization was compared by two different strategies as 1-Ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC)/N-Hydroxysuccinimide (NHS) coupling chemistry and hydrophobic interaction. Compared to conventional immunoassays carried out in plates or gels, microfluidic based immunoassays grant a lot of advantages such as a consumption of little samples and reagents, shorter analysis time, and higher efficiency...
May 15, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
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