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https://www.readbyqxmd.com/read/28078544/epistaxis-during-nasotracheal-intubation-a-randomized-trial-of-the-parker-flex-tip%C3%A2-nasal-endotracheal-tube-with-a-posterior-facing-bevel-versus-a-standard-nasal-rae-endotracheal-tube
#1
Rosie Earle, Enda Shanahan, Himat Vaghadia, Andrew Sawka, Raymond Tang
PURPOSE: Nasotracheal intubation is a widely performed technique to facilitate anesthesia induction during oral, dental, and maxillofacial surgeries. The technique poses several risks not encountered with oropharyngeal intubation, most commonly epistaxis due to nasal mucosal abrasion. The purpose of this study was to test whether the use of the Parker Flex-Tip™ (PFT) nasal endotracheal tube (ETT) with a posterior facing bevel reduces epistaxis when compared with the standard nasal RAE ETT with a leftward facing bevel...
January 11, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28074374/can-we-predict-the-perioperative-pulmonary-complications-before-laparoscopic-sleeve-gastrectomy-original-research
#2
Nurhan Atilla, Huseyin Arpag, Fulsen Bozkus, Hasan Kahraman, Emrah Cengiz, Ertan Bulbuloglu, Semi Atilla
BACKGROUND: The increasing prevalence of obesity in worldwide is one of the most serious chronic public health problems and is considered to be a global epidemic. Bariatric surgical procedures have also been applied more often with increased prevalence of obesity. As a result, the incidence of surgical complications has increased. Preoperative evaluation is quite important for these patients. AIMS: The aim of our study is to determine the predictors of perioperative pulmonary complications of laparoscopic sleeve gastrectomy...
January 10, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28066595/pulmonary-function-test-findings-in-patients-with-acute-inhalation-injury-caused-by-smoke-bombs
#3
Lu Cao, Xin-Gang Zhang, Jian-Guo Wang, Han-Bin Wang, Yi-Bing Chen, Da-Hui Zhao, Wen-Fang Shi, Li-Xin Xie
BACKGROUND: This study aimed to determine the effects of smoke bomb-induced acute inhalation injury on pulmonary function at different stages of lung injury. METHODS: We performed pulmonary function tests (PFTs) in 15 patients with acute inhalation injury from days 3 to 180 after smoke inhalation. We measured the trace element zinc in whole blood on days 4 and 17, and correlations of zinc levels with PFTs were performed. RESULTS: In the acute stage of lung injury (day 3), 3 of 11 patients with mild symptoms had normal pulmonary function and 8 patients with restrictive ventilatory dysfunction and reduced diffusing capacity...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28048542/we-ab-bra-06-4dct-ventilation-a-novel-imaging-modality-for-thoracic-surgical-evaluation
#4
Y Vinogradskiy, M Jackson, L Schubert, B Jones, R Castillo, E Castillo, T Guerrero, J Mitchell, B Kavanagh, M Miften
PURPOSE: The current standard-of-care imaging used to evaluate lung cancer patients for surgical resection is nuclear-medicine ventilation. Surgeons use nuclear-medicine images along with pulmonary function tests (PFT) to calculate percent predicted postoperative (%PPO) PFT values by estimating the amount of functioning lung that would be lost with surgery. 4DCT-ventilation is an emerging imaging modality developed in radiation oncology that uses 4DCT data to calculate lung ventilation maps...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048395/we-fg-206-07-assessing-the-lung-function-of-patients-with-non-small-cell-lung-cancer-using-hyperpolarized-xenon-129-dissolved-phase-mri
#5
K Qing, J Mugler, Q Chen
PURPOSE: Hyperpolarized xenon-129 dissolved-phase MRI is the first imaging technique that allows 3-dimensional regional mapping of ventilation and gas uptake by tissue and blood the in human lung. Multiple outcome measures can be produced from this method. Existing studies in subjects with major lung diseases compared to healthy controls demonstrated high sensitivities of this method to pulmonary physiological factors including ventilation, alveolar tissue density, surface-to-volume ratio, pulmonary perfusion and gas-blood barrier thickness...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046169/effect-of-shade-on-animal-welfare-growth-performance-and-carcass-characteristics-in-large-pens-of-beef-cattle-fed-a-beta-agonist-in-a-commercial-feedlot
#6
J A Hagenmaier, C D Reinhardt, S J Bartle, D U Thomson
Feedlot cattle ( = 1,395; BW = 568 ± 43 kg) were used to evaluate the effects of shade on animal welfare, growth performance, and carcass quality during the summer of 2013 in a Kansas commercial feedlot. Seven lots of predominately black steers and heifers (4 and 3, respectively) visually determined to be approaching the final mo on feed were identified, randomly gate-sorted, and allocated to pens located across the feed alley from each other to receive 1 of 2 treatments: 1) Shade (mean shade area = 1.5 m/ animal) or 2) No shade...
December 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/28045242/evidence-for-periprocedural-antiplatelet-therapy-heparinization-and-bridging-of-coumarin-therapy-in-carotid-revascularization
#7
Art Brand, Gert J DE Borst
Thromboembolism prevention is a crucial factor determining both the natural outcome and outcome of intervention of stenotic atherosclerotic carotid artery pathology. Roughly 80% of all natural course cerebral ischemic events are caused by thromboembolism, versus 20% due to hemodynamic insufficiency. The risk of periprocedural cerebral (micro) thromboembolization during carotid revascularization is considered to be even higher, with a higher rate in carotid artery stenting (CAS) as compared to carotid endarterectomy (CEA)...
January 3, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28039653/effect-of-ultrasound-guided-phrenic-nerve-block-on-shoulder-pain-after-laparoscopic-cholecystectomy-a-prospective-randomized-controlled-trial
#8
Myung Sub Yi, Won Joong Kim, Min Kyoung Kim, Hyun Kang, Yong-Hee Park, Yong Hun Jung, Seung Eun Lee, Hwa Yong Shin
BACKGROUND: Post-laparoscopic shoulder pain (PLSP) frequently follows a laparoscopic cholecystectomy. A proposed mechanism for PLSP is the irritation or injury of the phrenic nerve by the CO2 pneumoperitoneum during laparoscopic surgery. Here, we investigated whether a phrenic nerve block (PNB), performed under ultrasound guidance, could reduce the incidence and severity of PLSP after laparoscopic cholecystectomy. METHOD: Sixty patients were randomized into two groups, with one group receiving PNB with 4 ml (30 mg) of 0...
December 30, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/28039206/endoplasmic-reticulum-chaperone-gp96-controls-actomyosin-dynamics-and-protects-against-pore-forming-toxins
#9
Francisco Sarmento Mesquita, Cláudia Brito, Maria J Mazon Moya, Jorge Campos Pinheiro, Serge Mostowy, Didier Cabanes, Sandra Sousa
During infection, plasma membrane (PM) blebs protect host cells against bacterial pore-forming toxins (PFTs), but were also proposed to promote pathogen dissemination. However, the details and impact of blebbing regulation during infection remained unclear. Here, we identify the endoplasmic reticulum chaperone Gp96 as a novel regulator of PFT-induced blebbing. Gp96 interacts with non-muscle myosin heavy chain IIA (NMHCIIA) and controls its activity and remodelling, which is required for appropriate coordination of bleb formation and retraction...
December 30, 2016: EMBO Reports
https://www.readbyqxmd.com/read/28025138/functional-analysis-of-hspa1a-and-hspa8-in-parturition
#10
Junnan Geng, Huanan Li, Cong Huang, Jin Chai, Rong Zheng, Fenge Li, Siwen Jiang
Many factors are involved in parturition, such as apoptosis, inflammatory mediators, and hormones. Previous studies indicated that HSP70 directly or indirectly regulates apoptosis, inflammatory immune response and hormone stimulus. To gain new insights into molecular mechanism underlying HSP70 for regulating parturition, we overexpressed and knocked down two representative members of HSP70 (HSPA1A and HSPA8) through transfection of their recombinant plasmid and si-RNA separately in WISH (human amniotic epithelial) cells...
December 23, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28018523/long-term-outcomes-of-stereotactic-body-radiation-therapy-sbrt-with-fiducial-tracking-for-inoperable-stage-i-non-small-cell-lung-cancer-nsclc
#11
Jonathan W Lischalk, Stephanie M Woo, Shaan Kataria, Nima Aghdam, Ima Paydar, Michael C Repka, Eric D Anderson, Brian T Collins
BACKGROUND: Stereotactic body radiation therapy (SBRT) for stage I non-small cell lung cancer (NSCLC) is considered standard of care in the medically inoperable patient population. Multiple methods of SBRT delivery exist including fiducial-based tumor tracking, which allows for smaller treatment margins and avoidance of patient immobilization devices. We explore the long-term clinical outcomes of this novel fiducial-based SBRT method. METHODS: In this single institutional retrospective review, we detail the outcomes of medically inoperable pathologically confirmed stage I NSCLC...
2016: Journal of Radiation Oncology
https://www.readbyqxmd.com/read/28017791/conditions-to-minimize-soft-single-biomolecule-deformation-when-imaging-with-atomic-force-microscopy
#12
Christian Godon, Jean-Marie Teulon, Michael Odorico, Christian Basset, Matthieu Meillan, Luc Vellutini, Shu-Wen W Chen, Jean-Luc Pellequer
A recurrent interrogation when imaging soft biomolecules using atomic force microscopy (AFM) is the putative deformation of molecules leading to a bias in recording true topographical surfaces. Deformation of biomolecules comes from three sources: sample instability, adsorption to the imaging substrate, and crushing under tip pressure. To disentangle these causes, we measured the maximum height of a well-known biomolecule, the tobacco mosaic virus (TMV), under eight different experimental conditions positing that the maximum height value is a specific indicator of sample deformations...
December 22, 2016: Journal of Structural Biology
https://www.readbyqxmd.com/read/27996290/determination-of-fractional-exhaled-nitric-oxide-feno-reference-values-in-healthy-thai-population
#13
Yiwa Suksawat, Punchama Pacharn, Orathai Jirapongsananuruk
BACKGROUND: Fractional exhaled nitric oxide (FENO) level is directly correlated with airway inflammation in asthma patients. The objective of this study was to define normal FENO levels in healthy Thai volunteers. METHODS: This prospective cohort study was conducted in healthy Thai volunteers aged ≥5 years. Demographic and clinical data were recorded and pulmonary function test (PFT) was performed. FENO was measured using a chemiluminescence nitric oxide analyzer...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27987250/lung-disease-severity-in-idiopathic-pulmonary-fibrosis-is-more-strongly-associated-with-impedance-measures-of-bolus-reflux-than-ph-parameters-of-acid-reflux-alone
#14
S Gavini, L F Borges, R T Finn, W-K Lo, H J Goldberg, R Burakoff, N Feldman, W W Chan
BACKGROUND: Gastroesophageal reflux (GER) has been associated with idiopathic pulmonary fibrosis (IPF). Pathogenesis may be related to chronic micro-aspiration. We aimed to assess objective measures of GER on multichannel intraluminal impedance and pH study (MII-pH) and their relationship with pulmonary function testing (PFT) results, and to compare the performance of pH/acid reflux parameters vs corresponding MII/bolus parameters in predicting pulmonary dysfunction in IPF. METHODS: This was a retrospective cohort study of IPF patients undergoing prelung transplant evaluation with MII-pH off acid suppression, and having received PFT within 3 months...
December 16, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27942382/a-case-report-giant-intra-abdominal-liposarcoma-presenting-acute-renal-failure
#15
Kazim Duman, Mustafa Girgin, Gokhan Artas
INTRODUCTION: Liposarcomas represent 20-30% of adult soft tissue tumors and its abdominal localization occurs only in 5% of cases. Most are asymptomatic, but few present with abdominal mass and pain, fatigue, nausea, vomiting. They infiltrate adjacent organs and cause intestinal obstruction, intestinal ischemia-perforation, hydronephrosis, ureteric fistula and even aortic rupture. Here we aimed to report a rare case of a giant liposarcoma which originated from mesentery. PRESENTATION OF CASE: A 45-year-old male presented with slightly abdomen distention, urinary retention, oliguria since fifteen days...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27933793/differential-effect-of-membrane-composition-on-the-pore-forming-ability-of-four-different-sea-anemone-actinoporins
#16
Sara García-Linares, Esperanza Rivera-de-Torre, Koldo Morante, Kouhei Tsumoto, Jose M M Caaveiro, José G Gavilanes, J Peter Slotte, Álvaro Martínez-Del-Pozo
Sea anemone actinoporins constitute a protein family of multigene pore-forming toxins (PFT). Equinatoxin II (EqtII), fragaceatoxin C (FraC), and sticholysins I and II (StnI and StnII, respectively), produced by three different sea anemone species, are the only actinoporins whose molecular structures have been studied in depth. These four proteins show high sequence identities and practically coincident three-dimensional structures. However, their pore-forming activity can be quite different depending on the model lipid system employed, a feature that has not been systematically studied before...
December 6, 2016: Biochemistry
https://www.readbyqxmd.com/read/27933085/plant-physiological-morphological-and-yield-related-responses-to-night-temperature-changes-across-different-species-and-plant-functional-types
#17
Panpan Jing, Dan Wang, Chunwu Zhu, Jiquan Chen
Land surface temperature over the past decades has shown a faster warming trend during the night than during the day. Extremely low night temperatures have occurred frequently due to the influence of land-sea thermal difference, topography and climate change. This asymmetric night temperature change is expected to affect plant ecophysiology and growth, as the plant carbon consumption processes could be affected more than the assimilation processes because photosynthesis in most plants occurs during the daytime whereas plant respiration occurs throughout the day...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27932051/functional-and-exercise-limitations-after-a-first-episode-of-pulmonary-embolism-results-of-the-elope-prospective-cohort-study
#18
Susan R Kahn, Andrew M Hirsch, Arash Akaberi, Paul Hernandez, David R Anderson, Philip S Wells, Marc Rodger, Susan Solymoss, Michael J Kovacs, Lawrence Rudski, Avi Shimony, Carole Dennie, Christopher Rush, William H Geerts, Shawn D Aaron, John T Granton
BACKGROUND: We aimed to determine the frequency and predictors of exercise limitation after pulmonary embolism (PE), and to assess its association with health-related quality of life (HRQOL) and dyspnea. METHODS: 100 patients with acute PE were recruited at five Canadian hospitals from 2010-2013. Cardiopulmonary exercise testing (CPET) was performed at 1 and 12 months. Quality of life, dyspnea, six-minute walk distance (6MWD), residual clot burden (perfusion (Q) scan; CT pulmonary angiography (CTPA)), cardiac function (echocardiogram) and pulmonary function tests (PFT) were measured during follow-up...
December 5, 2016: Chest
https://www.readbyqxmd.com/read/27927570/exercise-tolerance-in-children-with-early-onset-scoliosis-growing-rod-treatment-graduates
#19
Kelly A Jeans, Charles E Johnston, Wilshaw R Stevens, Dong-Phuong Tran
STUDY DESIGN: Prospectively enrolled early-onset scoliosis (EOS) patients undergoing growing rod treatment, who have had no surgery for >1 year and/or have received definitive fusion (growing rod "graduates"). OBJECTIVES: To assess oxygen consumption during exercise and determine if a diminished conventional pulmonary function test (PFT) correlates with metabolic, pulmonary, and cardiovascular measures during exercise. SUMMARY OF BACKGROUND DATA: Based on clinical impression and sequential PFT values, EOS patients who have undergone extensive treatment are thought to have limited capacity during exercise...
November 2016: Spine Deformity
https://www.readbyqxmd.com/read/27925582/remote-depth-based-lung-function-assessment
#20
Vahid Soleimani, Majid Mirmehdi, Dima Damen, James Dodd, Sion Hannuna, Charles Sharp, Massimo Camplani, Jason Viner
OBJECTIVE: We propose a remote, non-invasive approach to develop Pulmonary Function Testing (PFT) using a depth sensor. METHOD: After generating a point cloud from scene depth values, we construct a 3D model of the subject's chest. Then, by estimating the chest volume variation throughout a sequence, we generate volume-time and flow-time data for two prevalent spirometry tests: Forced Vital Capacity (FVC) and Slow Vital Capacity (SVC). Tidal volume and main effort sections of volume-time data are analysed and calibrated separately to remove the effects of a subject's torso motion...
December 1, 2016: IEEE Transactions on Bio-medical Engineering
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