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upper crossed syndrome

Ivan R B Godoy, Edgar Leonardo Martinez-Salazar, Alireza Eajazi, Pedro R Genta, Miriam A Bredella, Martin Torriani
OBJECTIVE: To examine associations between tongue adiposity with upper airway measures, whole-body adiposity and gender. We hypothesized that increased tongue adiposity is higher in males and positively associated with abnormal upper airway measures and whole-body adiposity. METHODS: We studied subjects who underwent whole-body positron emission tomography/computed tomography to obtain tongue attenuation (TA) values and cross-sectional area, pharyngeal length (PL) and mandibular plane to hyoid distance (MPH), as well as abdominal circumference, abdominal subcutaneous and visceral (VAT) adipose tissue areas, neck circumference (NC) and neck adipose tissue area...
November 2016: Metabolism: Clinical and Experimental
Holly L Harper, Jesse K McKenney, Brandie Heald, Andrew Stephenson, Steven C Campbell, Thomas Plesec, Cristina Magi-Galluzzi
Increased risk for upper tract urothelial carcinoma is described in patients with Lynch syndrome, caused by germline mutations in mismatch repair genes. We aimed to identify the frequency of mismatch repair protein loss in upper tract urothelial carcinoma and its potential for identifying an association with Lynch syndrome. We queried our database to identify upper tract urothelial carcinomas. Patients were cross-referenced for history of colorectal carcinoma or other common Lynch syndrome-associated neoplasms to enrich for potential Lynch syndrome cases...
October 7, 2016: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
Molla Taye, Mekbeb Afework, Wondwossen Fantaye, Ermias Diro, Alemayehu Worku
BACKGROUND: Birth defects are defined as structural and functional defects that develop during the organogenesis period and present at birth or detected later in life. They are one of the leading causes of infant and child mortality, morbidity, and long term disability. The magnitude of birth defects varies from country to country and from race/ethnicity to race/ethnicity, and about 40-60% of their causes are unknown. The known causes of birth defects are genetic and environmental factors which may be prevented...
2016: PloS One
Mariem Rekik, Khaoula Achour, Anouer Abdallah, Sonia Lebib, Imen Miri, Fatima Zahra Ben Salah, Catherine Dziri
OBJECTIVE: The aim of our study was to assess the bladder and sphincter function after brain injury (BI) and to review their association with quality of life (QOL). MATERIAL/PATIENTS AND METHODS: We conducted a cross-sectional study, including patients referred to physical and rehabilitation medicine department at the Med Kassab Institute of Orthopedics. The initial gravity data were collected. The bladder-sphincter assessment included evaluation of the urine drain mode, the irritative disorders, obstructive disorders, disorders of transit and the existence of secondary anal lesions...
September 2016: Annals of Physical and Rehabilitation Medicine
Vera Celic, Anka Majstorovic, Biljana Pencic-Popovic, Aleksandra Sljivic, Natalia Lopez-Andres, Ignacio Roy, Elena Escribano, Maite Beunza, Amaia Melero, Federico Floridi, Laura Magrini, Rossella Marino, Gerardo Salerno, Patrizia Cardelli, Salvatore Di Somma
BACKGROUND: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family. Considering that metabolic syndrome (MetS) is accompanied by a proinflammatory state, we aimed to assess the relationship between sST2 and left ventricular (LV) structure and function in patients with MetS. METHODS: A multicentric, cross-sectional study was conducted on180 MetS subjects with normal LV ejection fraction as determined by echocardiography...
November 2016: Annals of Laboratory Medicine
Arikin Abdeyrim, Liang Tang, Arzugl Muhamat, Kelimu Abudeyrim, YongPing Zhang, NanFang Li, Yinchun Wang, Minghua Zhao
BACKGROUND: Inability to maintain upper-airway patency during sleep is a cause of obstructive sleep apnea (OSA) and its sequelae. The associated syndrome (OSAS) is common in obese populations, currently, nocturnal polysomnography is the gold standard for diagnosing this conditions, but the diagnostic procedures are expensive and time-consuming. Therefore, identification of new markers of OSAS would be useful. This study aims to examine the receiver operating characteristics of impulse oscillometry (IOS) parameters for the prediction of OSAS in preobese and obese snoring patients...
2016: BMC Pulmonary Medicine
Jie-Feng Huang, Gong-Ping Chen, Bi-Ying Wang, Han-Sheng Xie, Jian-Ming Zhao, Li-Hua Wu, Li-Da Chen, Qi-Chang Lin
BACKGROUND: The purpose of this observational study was to investigate the relationship between upper-airway configuration assessed by CT imaging during the Müller maneuver state and the severity of obstructive sleep apnea syndrome (OSAS). METHODS: A total of 358 snoring subjects who underwent standard polysomnography and upper-airway configuration by using CT imaging were enrolled. According to the apnea-hypopnea index (AHI), subjects were classified into 4 groups: snoring group (simple snoring), AHI < 5; mild OSAS, 5 ≤ AHI < 15; moderate OSAS, 15 ≤ AHI < 30; and severe OSAS, AHI ≥ 30...
August 16, 2016: Respiratory Care
Dorte Glintborg, Maria Houborg Petersen, Pernille Ravn, Anne Pernille Hermann, Marianne Andersen
INTRODUCTION: Polycystic ovary syndrome (PCOS) is characterized by obesity and insulin resistance. Measures of regional obesity may be used to predict insulin resistance. In the present study we compared fat distribution in patients with PCOS vs. controls and established the best measure of fat mass to predict insulin resistance in patients with PCOS MATERIAL AND METHODS: The study was cross-sectional in an academic tertiary-care medical center in 167 premenopausal women with PCOS and 110 controls matched for ethnicity, BMI and age...
August 16, 2016: Acta Obstetricia et Gynecologica Scandinavica
Dorothée C van Trier, Anna M C Vos, Renske W Draaijer, Ineke van der Burgt, Jos M Th Draaisma, Johannes R M Cruysberg
PURPOSE: To determine the full spectrum of ocular manifestations in patients with Noonan syndrome (NS). DESIGN: Prospective cross-sectional clinical and genetic study in a tertiary referral center. PARTICIPANTS: Twenty-five patients with NS (mean age, 14 years; range, 8 months-25 years) clinically diagnosed by validated criteria. METHODS: All patients were examined by the same team following a detailed study protocol...
October 2016: Ophthalmology
Yubing Tong, Jayaram K Udupa, Sanghun Sin, Zhengbing Liu, E Paul Wileyto, Drew A Torigian, Raanan Arens
PURPOSE: Quantitative image analysis in previous research in obstructive sleep apnea syndrome (OSAS) has focused on the upper airway or several objects in its immediate vicinity and measures of object size. In this paper, we take a more general approach of considering all major objects in the upper airway region and measures pertaining to their individual morphological properties, their tissue characteristics revealed by image intensities, and the 3D architecture of the object assembly...
2016: PloS One
Mieke Maris, Stijn Verhulst, Marek Wojciechowski, Paul Van de Heyning, An Boudewyns
OBJECTIVE: To evaluate the outcome of adenotonsillectomy (AT) in a cohort of children with Down syndrome (DS) and obstructive sleep apnoea (OSA). DESIGN: Retrospective, cross-sectional study. SETTING: Tertiary care centre. PATIENTS: Children with DS and OSA, without previous upper airway (UA) surgery. INTERVENTIONS: AT and full overnight polysomnography. MAIN OUTCOME RESULTS: A significant improvement of the obstructive apnoea-hypopnoea index (oAHI) after AT was obtained...
August 2, 2016: Archives of Disease in Childhood
David M Wootton, Sanghun Sin, Haiyan Luo, Alireza Yazdani, Joseph M McDonough, Mark E Wagshul, Carmen R Isasi, Raanan Arens
Obstructive sleep apnea syndrome (OSAS) is associated with anatomical abnormalities restricting upper airway size and functional factors decreasing pharyngeal dilator activity in sleep. In this study we hypothesized that OSAS is also associated with altered pharyngeal mechanical compliance during wakefulness. Five OSAS and six control obese girls between 14 and 18 years of age were studied. All underwent polysomnography, critical closing pressure (Pcrit) studies, and dynamic MRI of the upper airway during awake tidal breathing...
October 1, 2016: Journal of Applied Physiology
Romeo Patini, Mariantonietta Arrica, Enrico Di Stasio, Patrizia Gallenzi, Massimo Cordaro
OBJECTIVES: A systematic review was conducted to assess the effectiveness of MRI in evaluating upper airway structures in children affected by obstructive sleep apnoea syndrome (OSAS). METHODS: A literature search was performed in the Cochrane Central Register of Controlled Trials, Web of Science, Scopus and PubMed databases from their inception to 31/03/2016, including available randomized controlled trials and controlled clinical trials published in English assessing the use of MRI integrated with traditional polysomnography (PSG) among children up to 15 years of age affected by OSAS...
September 2016: Dento Maxillo Facial Radiology
Saurav Jyoti Patgiri, Himangshu Mazumdar, Lahari Saikia
INTRODUCTION: Co-infection of Japanese Encephalitis (JE) and Cysticercosis is attributed mainly to the common epidemiological features between the two diseases. Not much is known about the clinical implications of one infection over the other. AIM: The study aimed at establishing whether JE-Cysticercosis co-infection is prevalent in the Upper Assam districts and to explore additional details about such co-infections both clinically and epidemiologically. MATERIALS AND METHODS: The present study was a retrospective cross-sectional hospital based study conducted between July 2013 and June 2014 and included 272 Acute Encephalitis Syndrome (AES) patients...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
P J Liu, F Ma, H P Lou, Y N Zhu
OBJECTIVES: Body roundness index (BRI) and body adiposity index (BAI) have been recently proposed to assess obesity. The objectives of this cross-sectional study were to compare their potential for identifying metabolic syndrome (MetS) with traditional obesity indices in Chinese postmenopausal women. METHODS: A total of 817 participants were involved in this study. Odds ratio and corresponding 95% confidence intervals (CI) between MetS and all indices were evaluated by binary logistic regression analysis...
October 2016: Climacteric: the Journal of the International Menopause Society
M L Avila, L R Brandão, S Williams, L C Ward, M I Montoya, J Stinson, A Kiss, I Lara-Corrales, B M Feldman
OBJECTIVE: Our goal was to conduct the item generation and piloting phases of a new discriminative and evaluative tool for pediatric post-thrombotic syndrome. METHODS: We followed a formative model for the development of the tool, focusing on the signs/symptoms (items) that define post-thrombotic syndrome. For item generation, pediatric thrombosis experts and subjects diagnosed with extremity post-thrombotic syndrome during childhood nominated items. In the piloting phase, items were cross-sectionally measured in children with limb deep vein thrombosis to examine item performance...
August 2016: Thrombosis Research
Marcela Silva Lima, Carolina Maria Fontes Ferreira Nader, Letícia Paiva Franco, Zilda Maria Alves Meira, Flavio Diniz Capanema, Roberto Eustáquio Santos Guimarães, Helena Maria Gonçalves Becker
INTRODUCTION: Adenotonsillar hyperplasia (ATH) and allergic rhinitis (AR) are the most common causes of upper airway obstruction in children. Such diseases, by affecting the upper airways, can cause chronic alveolar hypoventilation, pulmonary vasoconstriction and pulmonary hypertension, which in some cases, are irreversible. OBJECTIVE: This cross-sectional study aimed to evaluate the prevalence of pulmonary hypertension in two groups of mouth-breathing (MB) 2-12 year old children with ATH and isolated allergic rhinitis, through Doppler echocardiography...
June 8, 2016: Brazilian Journal of Otorhinolaryngology
Ommara Jamil, Shahid Sarwar, Zahid Hussain, Raja Omer Fiaz, Ram Dev Chaudary
OBJECTIVE: To determine the association between functional dyspepsia and the severity of depression. STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: Department of Medicine, King Edward Medical University/Mayo Hospital, Lahore, from September 2012 till January 2013. METHODOLOGY: After taking informed written consent, patients with symptoms of dyspepsia fulfilling the Rome III criteria were included in the study...
June 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Ester Cerezo-Téllez, María Torres-Lacomba, Orlando Mayoral-Del Moral, Beatriz Sánchez-Sánchez, Jan Dommerholt, Carlos Gutiérrez-Ortega
BACKGROUND: Chronic non-specific neck pain is a frequent complaint. It is a recognized medical and socioeconomic problem and a frequent cause of job absenteeism. In recent years, case reports about myofascial pain syndrome (MPS) are emerging among patients suffering from pain. MPS is a regional pain syndrome characterized by myofascial trigger points (MTrP) in palpable taut bands of skeletal muscle that refer pain to a distance, and that can cause distant motor and autonomic effects. OBJECTIVE: To assess the prevalence of active and latent MTrPs in subjects suffering from chronic non-specific neck pain...
June 20, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Won-Sik Bae, Hyun-Ok Lee, Jae-Wook Shin, Keon-Cheol Lee
[Purpose] The purpose of this study was to determine the effectiveness of strength and stretching exercises on upper crossed syndrome. [Subjects and Methods] After measuring cervical alignment using the Global Posture System, 30 students with forward head posture were selected and divided into two groups. The experimental group (n=15) participated in strength and stretching exercises, three times per week for 4 weeks. The control group (n=15) did not participate in the exercises. The exercise program comprised middle and lower trapezius strength exercises and levator scapulae and upper trapezius stretching exercises...
May 2016: Journal of Physical Therapy Science
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