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https://www.readbyqxmd.com/read/28735371/identifying-symptoms-of-distress-in-youth-living-with-neurofibromatosis-type-1-nf1
#1
Lori Wiener, Haven Battles, Sima Zadeh Bedoya, Andrea Baldwin, Brigitte C Widemann, Maryland Pao
Children and adolescents with Neurofibromatosis type 1 (NF1) are at increased risk for wide-ranging behavioral, developmental, and cognitive impairments and decreased quality of life. To date, no psychosocial screening tool has been developed to quickly assess the symptoms that 1) can be addressed during routine medical appointments in children with NF1, 2) can produce interpretable and actionable results, 3) can be integrated into medical care, and 4) can quickly identify patients at risk in order to better address that the provision of appropriate care are available...
July 23, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28735260/aetiological-investigations-in-early-developmental-impairment-are-they-worth-it
#2
Anthony Richard Hart, Ruchi Sharma, Mark Atherton, Samer Alabed, Sally Simpson, Stuart Barfield, Judith Cohen, Nicholas McGlashan, Asha Ravi, Michael James Parker, Daniel Ja Connolly
OBJECTIVE: To study the frequency a diagnosis is made in children with early developmental impairment (EDI), and the contribution made to diagnosis by specific investigations. DESIGN: Retrospective case note review. SETTING: Community, neurodisability and neurology department at a UK tertiary centre. PARTICIPANTS: Children referred to determine the aetiology of EDI where a cause was not evident on history and examination...
July 22, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28735165/development-of-selective-attention-in-preschool-age-children-from-lower-socioeconomic-status-backgrounds
#3
Amanda Hampton Wray, Courtney Stevens, Eric Pakulak, Elif Isbell, Theodore Bell, Helen Neville
Although differences in selective attention skills have been identified in children from lower compared to higher socioeconomic status (SES) backgrounds, little is known about these differences in early childhood, a time of rapid attention development. The current study evaluated the development of neural systems for selective attention in children from lower SES backgrounds. Event-related potentials (ERPs) were acquired from 33 children from lower SES and 14 children from higher SES backgrounds during a dichotic listening task...
July 4, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28734813/incidence-and-types-of-pediatric-nystagmus
#4
David L Nash, Nancy N Diehl, Brian G Mohney
PURPOSE: To report the incidence, prevalent subtypes and clinical characteristics of pediatric nystagmus diagnosed over a 30-year period. DESIGN: Retrospective, population-based study METHODS: Using the Rochester Epidemiology Project, the medical records of all children (<19 years) diagnosed as residents in Olmsted County, Minnesota with any form of nystagmus from January 1, 1976, through December 31, 2005, were reviewed. RESULTS: Seventy-one children were diagnosed during the 30-year period, yielding an annual incidence of 6...
July 19, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28734509/global-disability-empowering-children-of-all-abilities
#5
REVIEW
Rebecca J Scharf, Angelina Maphula, Paige C Pullen, Rita Shrestha, Gaynell Paul Matherne, Reeba Roshan, Beena Koshy
Worldwide, children are often not meeting their developmental potential owing to malnutrition, infection, lack of stimulation, and toxic stress. Children with disabilities are more likely to experience poverty, neglect, and abuse, and are less likely to have adequate access to education and medical care. Early childhood developmental stimulation can improve language, learning, and future participation in communities. Therapeutic supports and endeavors to reduce stigma for people of all abilities strengthen communities and allow for human thriving...
August 2017: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/28734460/affected-anatomical-rich-club-and-structural-functional-coupling-in-young-offspring-of-schizophrenia-and-bipolar-disorder-patients
#6
Guusje Collin, Lianne H Scholtens, René S Kahn, Manon H J Hillegers, Martijn P van den Heuvel
BACKGROUND: Emerging evidence suggests disruptions in the wiring organization of the brain's network in schizophrenia (SZ) and bipolar disorder (BD). As the importance of genetic predisposition has been firmly established in these illnesses, children (offspring) of patients constitute an at-risk population. This study examines connectome organization in children at familial high risk for psychosis. METHODS: Diffusion-weighted magnetic resonance imaging scans were collected from 127 nonpsychotic offspring 8 to 18 years of age (average age = 13...
June 21, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28734240/decreased-levels-of-serum-fibroblast-growth-factor-2-in-children-with-autism-spectrum-disorder
#7
Erman Esnafoglu, Sema Nur Ayyıldız
The neurodevelopment and functioning of the central nervous system, and especially the cerebral cortex, have basic importance to understand neuropsychiatric disorders like autism. Fibroblast growth factor-2 (FGF-2) plays a very important role in the development and functioning of the cortex. FGF-2 is related to developmental processes in the central nervous system such as neurogenesis, migration, differentiation and survival. This study researched the serum FGF-2 levels in children with autism spectrum disorder (ASD)...
July 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28734200/rates-of-meaningful-change-in-the-mental-health-of-children-in-long-term-out-of-home-care-a-seven-to-nine-year-prospective-study
#8
Michael Tarren-Sweeney
Children residing in long-term out-of-home care have high rates of clinical-level mental health difficulties. However, the stability of these children's difficulties throughout their time in care is uncertain. This paper reports estimates of the seven- to nine-year stability of carer-reported scores on the Child Behavior Checklist (CBCL) and Assessment Checklists for Children (ACC) and Adolescents (ACA) for 85 children in long-term foster or kinship care. Prospective score changes on the CBCL total problems and ACC-ACA shared-item scales were assigned to one of four change groups: 'sustained mental health'; 'meaningful improvement'; 'no meaningful change'; and 'meaningful deterioration'...
July 19, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28733946/caretaker-awareness-of-health-care-provided-developmental-screening-increases-from-2007-to-2012
#9
Brian Barger, Andrew Roach, Gabriel Moreno
Objectives Developmental screening is considered critical to identifying children with developmental delays and disabilities so that they may receive early intervention. To date, only a handful of studies report data on the percentage of health care professionals (HCP) who provide developmental screening. These reports are limited by low participation rates and reporters being pediatricians who may be biased towards reporting higher rates of developmental screening. The purpose of this study is to verify reported increases by reporting on changes in caretakers' awareness of HCP provided developmental screening from 2007/2008 to 2011/2012...
July 21, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28731302/lead-ii-binding-in-metallothioneins
#10
Daisy L Wong, Maureen E Merrifield-MacRae, Martin J Stillman
Heavy metal exposure has long been associated with metallothionein (MT) regulation and its functions. MT is a ubiquitous, cysteine-rich protein that is involved in homeostatic metal response for the essential metals zinc and copper, as well as detoxification of heavy metals; the most commonly proposed being cadmium. MT binds in vivo to a number of metals in addition to zinc, cadmium and copper, such as bismuth. In vitro, metallation with a wide range of metals (especially mercury, arsenic, and lead) has been reported using a variety of analytical methods...
April 10, 2017: Metal Ions in Life Sciences
https://www.readbyqxmd.com/read/28730904/occupational-therapists-awareness-of-guidelines-for-assessment-and-diagnosis-of-developmental-coordination-disorder-mesure-selon-laquelle-les-ergoth%C3%A3-rapeutes-connaissent-les-lignes-directrices-relatives-%C3%A3-l-%C3%A3-valuation-et-au-diagnostic-du-trouble-du-d%C3%A3-veloppement
#11
Morgan Karkling, Alissa Paul, Jill G Zwicker
BACKGROUND: Developmental coordination disorder (DCD) is a motor skills disorder that can have negative lifelong psychosocial impacts if not diagnosed. Occupational therapists have a role in facilitating a diagnosis for children with DCD through assessment. PURPOSE: The purpose of this study was to determine the level of understanding of current DCD guidelines for assessment and diagnosis among occupational therapists working in paediatric settings in British Columbia, Canada...
June 2017: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://www.readbyqxmd.com/read/28730897/intervention-and-management-of-developmental-coordination-disorder-are-we-providing-evidence-based-services-intervention-et-traitement-d-un-trouble-du-d%C3%A3-veloppement-de-la-coordination-les-ergoth%C3%A3-rapeutes-fournissent-ils-des-services-fond%C3%A3-s-sur-les-faits
#12
Renée Withers, Yoyo Tsang, Jill G Zwicker
BACKGROUND: Occupational therapists are well positioned to provide intervention to improve outcomes for children with developmental coordination disorder. However, little is known about what occupational therapy services are provided for these children. PURPOSE: As part of a larger study exploring service provision for children with developmental coordination disorder, the purpose of this study was to examine intervention and referral practices of occupational therapists in British Columbia, Canada...
June 2017: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://www.readbyqxmd.com/read/28729951/young-children-do-not-require-perceptual-motor-feedback-to-solve-aesop-s-fable-tasks
#13
Rachael Miller, Sarah A Jelbert, Elsa Loissel, Alex H Taylor, Nicola S Clayton
Aesop's Fable tasks-in which subjects drop objects into a water-filled tube to raise the water level and obtain out-of-reach floating rewards -have been used to test for causal understanding of water displacement in both young children and non-human animals. However, a number of alternative explanations for success on these tasks have yet to be ruled out. One hypothesis is that subjects may respond to perceptual-motor feedback: repeating those actions that bring the reward incrementally closer. Here, we devised a novel, forced-choice version of the Aesop's Fable task to assess whether subjects can solve water displacement tasks when this type of feedback is removed...
2017: PeerJ
https://www.readbyqxmd.com/read/28729888/social-brain-circuitry-and-social-cognition-in-infants-born-preterm
#14
REVIEW
Angela Fenoglio, Michael K Georgieff, Jed T Elison
Preterm birth is associated with an increased risk of adverse neurologic, psychiatric, and cognitive outcomes. The brain circuits involved in processing social information are critical to all of these domains, but little work has been done to examine whether and how these circuits may be especially sensitive to prematurity. This paper contains a brief summary of some of the cognitive, psychiatric, and social outcomes associated with prematurity, followed by a description of findings from the modest body of research into social-cognitive development in infants and children born preterm...
2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/28729828/working-memory-profiles-in-hiv-exposed-uninfected-and-hiv-infected-children-a-comparison-with-neurotypical-controls
#15
Robyn Milligan, Kate Cockcroft
This study compared the working memory profiles of three groups of children, namely HIV-infected (HIV-I; n = 95), HIV-exposed, uninfected (HIV-EU; n = 86) and an HIV-unexposed, uninfected, (HIV-UU; n = 92) neurotypical control group. Working memory, an executive function, plays an important role in frontal lobe-controlled behaviors, such as motivation, planning, decision making, and social interaction, and is a strong predictor of academic success in school children. Memory impairments have been identified in HIV-I children, particularly in visuospatial processing...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28729533/common-brain-structure-findings-across-children-with-varied-reading-disability-profiles
#16
Mark A Eckert, Kenneth I Vaden, Amanda B Maxwell, Stephanie L Cute, Mulugeta Gebregziabher, Virginia W Berninger
Dyslexia is a developmental disorder in reading that exhibits varied patterns of expression across children. Here we examined the degree to which different kinds of reading disabilities (defined as profiles or patterns of reading problems) contribute to brain morphology results in Jacobian determinant images that represent local brain shape and volume. A matched-pair brain morphometry approach was used to control for confounding from brain size and research site effects in this retrospective multi-site study of 134 children from eight different research sites...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729328/comparative-safety-of-antiepileptic-drugs-for-neurological-development-in-children-exposed-during-pregnancy-and-breast-feeding-a-systematic-review-and-network-meta-analysis
#17
Areti Angeliki Veroniki, Patricia Rios, Elise Cogo, Sharon E Straus, Yaron Finkelstein, Ryan Kealey, Emily Reynen, Charlene Soobiah, Kednapa Thavorn, Brian Hutton, Brenda R Hemmelgarn, Fatemeh Yazdi, Jennifer D'Souza, Heather MacDonald, Andrea C Tricco
OBJECTIVES: Compare the safety of antiepileptic drugs (AEDs) on neurodevelopment of infants/children exposed in utero or during breast feeding. DESIGN AND SETTING: Systematic review and Bayesian random-effects network meta-analysis (NMA). MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were searched until 27 April 2017. Screening, data abstraction and quality appraisal were completed in duplicate by independent reviewers. PARTICIPANTS: 29 cohort studies including 5100 infants/children...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28728770/don-t-push-your-luck-educational-family-board-not-bored-game-for-school-age-children-living-with-chronic-conditions
#18
Andrea Kennedy, Lisa Semple, Kerri Alderson, Vanessa Bouskill, Janice Karasevich, Brenda Riske, Sheri van Gunst
PURPOSE: Children who are living with chronic conditions may be supported in self-care through enjoyable active learning and family social processes. This research focused on development and evaluation of "Don't Push Your Luck!", an educational board game designed to inspire family discussion about chronic conditions, and help affected children learn about self-care choices and consequences. DESIGN AND METHODS: Mixed-method research was conducted with families from one outpatient Cystic Fibrosis Clinic and four Hemophilia Treatment Centres in Canada and United States (N=72)...
July 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28728758/large-genetic-study-uncovers-14-new-genes-responsible-for-developmental-disorders-in-children
#19
Deborah L McBride
The exomes of 4293 families with individuals with undiagnosed developmental disorders were sequenced to identify de novo mutations. The researchers identified 14 new genetic disorders.
July 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28728674/utilizing-trauma-admissions-as-an-opportunity-to-identify-developmental-and-behavioral-concerns
#20
Stephanie K Serres, Catherine Chen
BACKGROUND: Developmental and behavioral problems are often underdiagnosed in the pediatric population, and are risk factors for injury from trauma. Early intervention for these concerns yields improved outcomes. No prior research has screened for these difficulties during pediatric trauma admissions. METHODS: The current study utilized "The Survey of Wellbeing of Young Children" (SWYC) to assess for possible areas of concern by parent report. Concerns were compared to the presence of screening documented in their pediatrician's last well-child visit note...
July 8, 2017: American Journal of Surgery
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