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https://www.readbyqxmd.com/read/28429376/daily-crying-prevalence-and-associated-factors-in-older-adult-persons-living-in-nursing-homes-findings-from-a-regional-study
#1
Alvisa Palese, Arianna Simeoni, Antonio Ranieri Zuttion, Barbara Ferrario, Sandra Ponta, Elisa Ambrosi
OBJECTIVES: The study aims to evaluate the prevalence of nursing home (NH) resident crying and associated factors at the individual and NH levels. DESIGN: A regional retrospective study design has been used. PARTICIPANTS AND SETTING: A total of 8875 residents, living in 105 NHs, were included. MEASUREMENTS: The occurrence of an episode of crying on at least a daily basis in the last month was the dependent variable; independent variables were set at individual and at the NH levels as reported in the Val...
April 21, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28428558/a-joint-analysis-of-influenza-associated-hospitalizations-and-mortality-in-hong-kong-1998-2013
#2
Peng Wu, Anne M Presanis, Helen S Bond, Eric H Y Lau, Vicky J Fang, Benjamin J Cowling
Influenza viruses may cause severe human infections leading to hospitalization or death. Linear regression models were fitted to population-based data on hospitalizations and deaths. Surveillance data on influenza virus activity permitted inference on influenza-associated hospitalizations and deaths. The ratios of these estimates were used as a potential indicator of severity. Influenza was associated with 431 (95% CrI: 358-503) respiratory deaths and 12,700 (95% CrI: 11,700-13,700) respiratory hospitalizations per year...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28425020/acoustic-properties-of-cries-in-12-month-old-infants-at-high-risk-of-autism-spectrum-disorder
#3
Lisa M Unwin, Ildiko Bruz, Murray T Maybery, Victoria Reynolds, Natalie Ciccone, Cheryl Dissanayake, Martha Hickey, Andrew J O Whitehouse
There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder (ASD) have an atypical pattern of cry, characterized by higher fundamental frequency and increased dysphonation. This prospective study collected multiple cry samples of 12-month old siblings of children with ASD (n = 22, 'high-risk' group) and 12-month olds with no family history of ASD (n = 27, 'low risk' group). While there was no difference between groups in the fundamental frequency or degree of phonation of the cry samples, the duration of each cry unit was significantly shorter in the high-risk siblings (p < ...
April 19, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28424073/systematic-review-with-network-meta-analysis-dual-therapy-for-high-risk-bleeding-peptic-ulcers
#4
Keda Shi, Zeren Shen, Guiqi Zhu, Fansheng Meng, Mengli Gu, Feng Ji
BACKGROUND: Adding a second endoscopic therapy to epinephrine injection might improve hemostatic efficacy in patients with high-risk bleeding ulcers but the optimum modality remains unknown. We aimed to estimate the comparative efficacy of different dual endoscopic therapies for the management of bleeding peptic ulcers through random-effects Bayesian network meta-analysis. METHODS: Different databases were searched for controlled trials comparing dual therapy versus epinephrine monotherapy or epinephrine combined with another second modality until September, 30 2016...
April 19, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28423740/prognosis-of-surgery-combined-with-different-adjuvant-therapies-in-esophageal-cancer-treatment-a-network-meta-analysis
#5
Shenglei Li, Hongtao Liu, Changying Diao, Xiaohui Wang, Ming Gao, Zongming Li, Lijie Song, Xianzheng Gao, Jing Han, Feng Wang, Wencai Li, Xinwei Han
This network meta-analysis was conducted to assess whether the efficacy of surgery with adjuvant therapies, including radiotherapy (RT+S), chemotherapy (CT+S), and chemoradiotherapy (CRT+S) have better performance in esophageal cancer treatment and management. PubMed and EMBASE were used to search for relevant trials. Both conventional pair-wise and network meta-analyses were carried out. The surface under the cumulative ranking curve (SUCRA) was used to rank interventions based on the efficacy of the treatment method...
March 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/28421767/base-layer-influence-on-protonated-aminosilane-gradient-wettability
#6
Kayesh M Ashraf, Chenyu Wang, Sithara S Nair, Kenneth J Wynne, Daniel A Higgins, Maryanne M Collinson
Protonated amine gradients have been prepared on silicon wafers via programmed controlled rate infusion (CRI) with varying degrees of hydrophobicity and characterized by X-ray photoelectron spectroscopy (XPS) and static and Wilhelmy plate dynamic contact angle measurements. Initially, base layers were spin coated from sols containing tetramethoxysilane (TMOS) and either phenyltrimethoxysilane (PTMOS), dimethyldimethoxysilane (DMDMOS), or octyltrimethoxysilane (OTMOS, C8). Amine gradients were then prepared from 3-aminopropyltriethoxysilane (APTEOS) via CRI...
April 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28416162/pharmacokinetics-of-buprenorphine-following-constant-rate-infusion-for-postoperative-analgesia-in-dogs-undergoing-ovariectomy
#7
Andrea Barbarossa, Julie Rambaldi, Massimo Giunti, Anna Zaghini, Marco Cunto, Daniele Zambelli, Simond Valgimigli, Francesco Santoro, Noemi Romagnoli
OBJECTIVE: To investigate the pharmacokinetics of buprenorphine and its main active metabolite, norbuprenorphine, after administration of an intravenous loading dose followed by constant rate infusion (CRI) in dogs. STUDY DESIGN: Prospective, clinical study. ANIMALS: A total of seven healthy dogs undergoing elective ovariectomy. METHODS: Buprenorphine was administered as a loading dose (intravenous bolus of 15 μg kg(-1)) followed by CRI (2...
January 11, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28414516/effects-of-having-preterm-infants-smell-amniotic-fluid-mother-s-milk-and-mother-s-odor-during-heel-stick-procedure-on-pain-physiological-parameters-and-crying-duration
#8
Dilek Küçük Alemdar, Funda Kardaş Özdemir
OBJECTIVE: The study aims to assess effects of having preterm infants smell amniotic fluid, mother's milk, and mother's odor during heel stick procedure on pain, physiological parameters, and crying duration. MATERIALS AND METHODS: The study was a randomized controlled experimental research. The population of the study was made up of preterm infants receiving treatment and care at a neonatal intensive care unit, where the study was conducted between January 2015 and March 2016...
April 17, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28411027/%C3%AE-caryophyllene-reduces-atherogenic-index-and-coronary-risk-index-in-hypercholesterolemic-rats-the-involvement-of-cardiac-oxidative-damage
#9
Matheus D Baldissera, Carine F Souza, Thirssa H Grando, Lenita M Stefani, Silvia G Monteiro
Hypercholesterolemia and cardiac oxidative damage have been implicated in the pathophysiology of atherosclerosis. In earlier studies, treatment using natural phytocannabinoid β-caryophyllene caused a hypolipemic effect, as well as ameliorated hepatic oxidative damage. In this regard, the present study aimed to investigate whether β-caryophyllene treatment was able to protect the cardiac tissue against hypercholesterolemic atherosclerosis, and to investigate the involvement of antioxidant mechanisms in this effect using a model of hypercholesterolemia induced by Triton WR-1339...
April 12, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28409870/comparative-efficacy-and-safety-of-anti-platelet-agents-in-cerebral-ischemic-disease-a-network-meta-analysis
#10
Da Wa, Pa Zhu, Ziwen Long
We performed this network meta-analysis (NMA) to enhance the corresponding evidence of the relative efficacy and safety of different anti-platelet agents in cerebral ischemic disease. PubMed and EMBASE were searched systematically for relevant studies. Outcomes were compared using odds ratios (ORs) and 95% credible intervals (CrI). Each agent was ranked according to the value of surface under the cumulative ranking curve (SUCRA). Publication bias was evaluated by funnel plots while consistency between direct and indirect comparison was analyzed by node splitting and heat plots...
April 14, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28409853/a-phase-1-study-of-the-cxcr4-antagonist-plerixafor-in-combination-with-high-dose-cytarabine-and-etoposide-in-children-with-relapsed-or-refractory-acute-leukemias-or-myelodysplastic-syndrome-a-pediatric-oncology-experimental-therapeutics-investigators-consortium
#11
Todd M Cooper, Edward Allan Racela Sison, Sharyn D Baker, Lie Li, Amina Ahmed, Tanya Trippett, Lia Gore, Margaret E Macy, Aru Narendran, Keith August, Michael J Absalon, Jessica Boklan, Jessica Pollard, Daniel Magoon, Patrick A Brown
BACKGROUND: Plerixafor, a reversible CXCR4 antagonist, inhibits interactions between leukemic blasts and the bone marrow stromal microenvironment and may enhance chemosensitivity. A phase 1 trial of plerixafor in combination with intensive chemotherapy in children and young adults with relapsed or refractory acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and myelodysplastic syndrome (MDS) was performed to determine a tolerable and biologically active dose. PROCEDURE: Plerixafor was administered daily for 5 days at four dose levels (6, 9, 12, and 15 mg/m(2) /dose) followed 4 hr later by high-dose cytarabine (every 12 hr) and etoposide (daily)...
April 14, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28404515/assessment-of-cardiovascular-risk-via-atherogenic-indices-in-patients-with-bipolar-disorder-manic-episode-and-alterations-with-treatment
#12
Tevfik Kalelioglu, Abdullah Genc, Nesrin Karamustafalioglu, Murat Emul
OBJECTIVES: Cardiovascular disease is one of the important cause of mortality among patients with Bipolar Disorder. Castelli Risk index I and II (CRI-I and II), Atherogenic Index of Plasma (AIP) and Atherogenic coefficient (AC) are new parameters in assessing cardiovascular risk. In this study we aimed to explore the status of cardiovascular risk factors and their alterations with treatment in manic episode. METHODS: Bipolar Disorder inpatients who were in manic episode and age-gender matched healthy controls were included in the study...
April 2, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28403994/risk-of-gastrointestinal-bleeding-with-direct-oral-anticoagulants-a-systematic-review-and-network-meta-analysis
#13
Nick Burr, Katie Lummis, Ruchit Sood, John Samuel Kane, Aaron Corp, Venkataraman Subramanian
BACKGROUND: Direct oral anticoagulants are increasingly used for a wide range of indications. However, data are conflicting about the risk of major gastrointestinal bleeding with these drugs. We compared the risk of gastrointestinal bleeding with direct oral anticoagulants, warfarin, and low-molecular-weight heparin. METHODS: For this systematic review and meta-analysis, we searched MEDLINE and Embase from database inception to April 1, 2016, for prospective and retrospective studies that reported the risk of gastrointestinal bleeding with use of a direct oral anticoagulant compared with warfarin or low-molecular-weight heparin for all indications...
February 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28401830/childhood-abuse-and-neglect-and-insecure-attachment-states-of-mind-in-adulthood-prospective-longitudinal-evidence-from-a-high-risk-sample
#14
K Lee Raby, Madelyn H Labella, Jodi Martin, Elizabeth A Carlson, Glenn I Roisman
The present report used data from the Minnesota Longitudinal Study of Risk and Adaptation to investigate the factor structure and childhood abuse and/or neglect related antecedents of adults' attachment states of mind in a high-risk sample. Adult Attachment Interviews (AAIs) were collected when participants were age 26 years (N = 164) and Current Relationship Interviews (CRIs) were collected from participants (N = 116) and their romantic partners when target participants were between ages 20 and 28 years (M = 25...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28395440/-prognostic-significance-of-blood-count-at-the-time-of-achieving-morphologic-leukemia-free-state-in-adults-with-acute-myeloid-leukemia
#15
X Ren, T Zhao, J Wang, H H Zhu, H Jiang, J S Jia, S M Yang, B Jiang, D B Wang, X J Huang, Q Jiang
Objective: To explore prognostic significance of blood count at the time of achieving first morphologic leukemia-free state[complete remission (CR, ANC ≥1×10(9)/L and PLT ≥100×10(9)/L) , CR with incomplete PLT recovery (CRp) and CR with incomplete ANC and PLT recovery (CRi) ]in adult patients with de novo acute myeloid leukemia (AML) . Methods: From January 2008 to February 2016, data of consecutive newly-diagnosed AML (non-APL) adults who received continuous chemotherapy in our hospital were analyzed retrospectively...
March 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/28392772/the-tromso-infant-faces-database-tif-development-validation-and-application-to-assess-parenting-experience-on-clarity-and-intensity-ratings
#16
Jana K Maack, Agnes Bohne, Dag Nordahl, Lina Livsdatter, Åsne A W Lindahl, Morten Øvervoll, Catharina E A Wang, Gerit Pfuhl
Newborns and infants are highly depending on successfully communicating their needs; e.g., through crying and facial expressions. Although there is a growing interest in the mechanisms of and possible influences on the recognition of facial expressions in infants, heretofore there exists no validated database of emotional infant faces. In the present article we introduce a standardized and freely available face database containing Caucasian infant face images from 18 infants 4 to 12 months old. The development and validation of the Tromsø Infant Faces (TIF) database is presented in Study 1...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28392770/emergence-of-functional-flexibility-in-infant-vocalizations-of-the-first-3-months
#17
Yuna Jhang, D Kimbrough Oller
Functional flexibility, as manifest in the use of any word or sentence to express different affective valences on different occasions, is required in linguistic communication and can be said to be an infrastructural property of language. Early infant vocalizations (protophones), believed to be precursors to speech, occur in the first month and are functionally different from non-speech-like signals (e.g., cries and laughs). Oller et al. (2013) showed that infants by 3 months used three different protophone types with a full range of affect as manifest in facial expression, from positive to neutral to negative...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28389627/efficacy-and-safety-of-traditional-chemotherapies-for-patients-with-ovarian-neoplasm-a-network-meta-analysis
#18
Lili Yang, Gongliang Guo, Liqun Sun, Chenhao Li, Haipeng Zhang
BACKGROUND: Ovarian neoplasm is a kind of high risky cancer among female. This paper assessed the efficacy and safety of twelve therapies and figured out the superior chemotherapeutic drug for ovarian cancer through network meta-analysis (NMA). METHOD: Eligible randomized controlled trials (RCTs) were retrieved from electronic databases. Primary outcomes concerning efficacy, overall survival (OS) and progression-free survival (PFS), were presented as hazard ratio (HR) and the associated 95% credible interval(CrI), while outcomes concerning safety were assessed by odds ratio (OR) and the corresponding 95% CrI...
March 30, 2017: Oncotarget
https://www.readbyqxmd.com/read/28385295/systematic-review-and-meta-analysis-fussing-and-crying-durations-and-prevalence-of-colic-in-infants
#19
Dieter Wolke, Ayten Bilgin, Muthanna Samara
OBJECTIVE: To determine the mean duration of fussing and crying and prevalence of colic using modified Wessel criteria in infants in the first 3 months of life. STUDY DESIGN: A systematic literature search was performed using the databases Medline, PsycINFO, and Embase. The major outcome measure was mean total fuss/cry duration during 24 hours at ages 1-2 weeks (11 samples), 3-4 weeks (6 samples), 5-6 weeks (28 samples), 8-9 weeks (9 samples), and 10-12 weeks (12 samples)...
March 28, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28382062/the-comparison-of-the-effects-of-massaging-and-rocking-on-infantile-colic
#20
Fatemah Nahidi, Nafiseh Gazerani, Parsa Yousefi, Ali Reza Abadi
INTRODUCTION: Infantile colic is a painful condition in the first months of infancy. This study was carried out with the aim of testing the hypothesis that massage treatment has a clinically relevant effect on this condition. MATERIALS AND METHODS: This randomized clinical trial was conducted among 100 infants of < 12 weeks of age with infantile colic. They were randomly assigned to either infant massage (n = 50) or rocking groups (n = 50). In the massage group, trained individuals taught the parents of the infants the massage technique and gave them a brochure...
January 2017: Iranian Journal of Nursing and Midwifery Research
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