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https://www.readbyqxmd.com/read/28110270/assessment-of-neonatal-pain-during-heel-prick-lancet-vs-needle-a-randomized-controlled-study
#1
Carl Britto, Suman P N Rao
BACKGROUND: Heel prick is a frequent painful procedure in newborns. A lancet or a 26-gauge needle is used for a heel prick in India. OBJECTIVE: To compare the pain caused by heel prick with a lancet or a 26-gauge needle in newborns admitted in the neonatal intensive care unit (NICU) using the preterm infant pain profile (PIPP). METHODS: This randomized controlled trial was conducted over 2 months in a Level III NICU with a sample size of 40 subjects (20 in each group), which was required for the study to have a power of 80% with an alpha error of 0...
January 21, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28105805/towards-3d-chemical-imaging-of-ternary-cu-sn-pb-alloys-using-femtosecond-laser-ablation-ionization-mass-spectrometry
#2
Valentine Grimaudo, Pavel Moreno-Garcia, Andreas Riedo, Stefan Meyer, Marek Tulej, Maike Brigitte Neuland, Miklós Mohos, Christoph Gütz, Siegfried R R Waldvogel, Peter Wurz, Peter Broekmann
Femtosecond Laser Ablation/Ionization Mass Spectrometry (LIMS) has been applied to probe the spatial element composition of three ternary Cu-Sn-Pb model bronze alloys (lead bronzes: CuSn10Pb10, CuSn7Pb15 and CuSn5Pb20), which were recently identified as high performance cathode materials in the context of electro-organic synthesis (dehalogenation, deoxygenation) of pharmaceutically relevant building blocks. The quantitative and spatially resolved element analysis of such cathode materials will help understanding the observed profound differences in their electrochemical reactivity and stability...
January 4, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28100518/stopping-antithrombotics-during-regional-anaesthesia-and-eye-surgery-crying-wolf
#3
EDITORIAL
C M Kumar, E Seet
No abstract text is available yet for this article.
February 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28098997/two-step-design-of-a-single-doped-white-phosphor-with-high-color-rendering
#4
Romain Gautier, Xueyan Li, Zhiguo Xia, Florian Massuyeau
A strategy to design step by step an inorganic single-doped white phosphor is demonstrated. The method consists in tuning different contributions of the emission by successively controlling the chemical compositions of the solid solution or nanosegregated host matrix and the oxidation states of the single dopant. We use this approach to design a white phosphor Na4CaMgSc4Si10O30:Eu with excellent color rendering (CRI > 90) which is similar to common mixed-phosphor light sources but for a single-phase. We show that this methodology can also be extended to other phosphors for use in diverse applications such as biomedicine or telecommunications...
January 18, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28097393/comparative-efficacy-and-safety-of-baricitinib-2%C3%A2-mg-and-4%C3%A2-mg-in-patients-with-active-rheumatoid-arthritis-a%C3%A2-bayesian-network-meta-analysis-of-randomized-controlled-trials
#5
Y H Lee, S-C Bae
OBJECTIVE: This study aimed to assess the relative efficacy and safety of once-daily baricitinib 2 mg and 4 mg administration in patients with active rheumatoid arthritis (RA). METHODS: In this network meta-analysis, randomized controlled trials (RCTs) examining the efficacy and safety of baricitinib in patients with active RA were included. A Bayesian network meta-analysis was conducted to combine the direct and indirect evidence from the RCTs. RESULTS: Seven RCTs involving 3461 patients met the inclusion criteria...
January 17, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28097071/the-fishing-and-natural-mortality-of-large-piscivorous-bull-trout-and-rainbow-trout-in-kootenay-lake-british-columbia-2008-2013
#6
Joseph L Thorley, Greg F Andrusak
BACKGROUND: Estimates of fishing and natural mortality are important for understanding, and ultimately managing, commercial and recreational fisheries. High reward tags with fixed station acoustic telemetry provides a promising approach to monitoring mortality rates in large lake recreational fisheries. Kootenay Lake is a large lake which supports an important recreational fishery for large Bull Trout and Rainbow Trout. METHODS: Between 2008 and 2013, 88 large (≥500 mm) Bull Trout and 149 large (≥500 mm) Rainbow Trout were marked with an acoustic transmitter and/or high reward ($100) anchor tags in Kootenay Lake...
2017: PeerJ
https://www.readbyqxmd.com/read/28095409/sick-children-crying-for-help-fostering-adverse-event-reports
#7
Gordon D Schiff
In a Perspective, Gordon Schiff discusses the importance of appropriately analyzing adverse event reports.
January 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28093383/effect-of-minimal-acupuncture-for-infantile-colic-a-multicentre-three-armed-single-blind-randomised-controlled-trial-acu-col
#8
Kajsa Landgren, Inger Hallström
BACKGROUND: Evidence for treating infantile colic with acupuncture is contradictory. AIM: To evaluate and compare the effect of two types of acupuncture versus no acupuncture in infants with colic in public child health centres (CHCs). METHODS: A multicentre, randomised controlled, single-blind, three-armed trial (ACU-COL) comparing two styles of acupuncture with no acupuncture, as an adjunct to standard care, was conducted. Among 426 infants whose parents sought help for colic and registered their child's fussing/crying in a diary, 157 fulfilled the criteria for colic and 147 started the intervention...
January 16, 2017: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/28091337/assessing-the-social-and-environmental-determinants-of-pertussis-epidemics-in-queensland-australia-a-bayesian-spatio-temporal-analysis
#9
X Huang, S Lambert, C Lau, R J Soares Magalhaes, J Marquess, M Rajmokan, G Milinovich, W Hu
Pertussis epidemics have displayed substantial spatial heterogeneity in countries with high socioeconomic conditions and high vaccine coverage. This study aims to investigate the relationship between pertussis risk and socio-environmental factors on the spatio-temporal variation underlying pertussis infection. We obtained daily case numbers of pertussis notifications from Queensland Health, Australia by postal area, for the period January 2006 to December 2012. A Bayesian spatio-temporal model was used to quantify the relationship between monthly pertussis incidence and socio-environmental factors...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28089137/a-comparison-of-cangrelor-prasugrel-ticagrelor-and-clopidogrel-in-patients-undergoing-percutaneous-coronary-intervention-a-network-meta-analysis
#10
Peter C Westman, Michael J Lipinski, Rebecca Torguson, Ron Waksman
BACKGROUND: Newer P2Y12 inhibitors have more rapid onset of platelet inhibition compared with clopidogrel, especially the intravenous P2Y12 inhibitor cangrelor. Direct comparisons between cangrelor and oral P2Y12 inhibitors ticagrelor and prasugrel do not exist. Thus, we performed a network meta-analysis to directly and indirectly compare different P2Y12 inhibitors in patients undergoing percutaneous coronary intervention (PCI). METHODS: MEDLINE/PubMed and ClinicalTrials...
October 21, 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28079510/a-comparison-of-discontinuation-rates-of-tofacitinib-and-biologic-disease-modifying-antirheumatic-drugs-in-rheumatoid-arthritis-a-systematic-review-and-bayesian-network-meta-analysis
#11
Sun-Kyeong Park, Min-Young Lee, Eun-Jin Jang, Hye-Lin Kim, Dong-Mun Ha, Eui-Kyung Lee
OBJECTIVES: The purpose of this study was to compare the discontinuation rates of tofacitinib and biologics (tumour necrosis factor inhibitors (TNFi), abatacept, rituximab, and tocilizumab) in rheumatoid arthritis (RA) patients considering inadequate responses (IRs) to previous treatment(s). METHODS: Randomised controlled trials of tofacitinib and biologics - reporting at least one total discontinuation, discontinuation due to lack of efficacy (LOE), and discontinuation due to adverse events (AEs) - were identified through systematic review...
January 5, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28069147/a-content-analysis-of-emotional-concerns-expressed-at-the-time-of-receiving-a-cancer-diagnosis-an-observational-study-of-consultations-with-adolescent-and-young-adult-patients-and-their-family-members
#12
Live Korsvold, Anneli Viktoria Mellblom, Arnstein Finset, Ellen Ruud, Hanne Cathrine Lie
PURPOSE: Little is known about the emotional concerns expressed by adolescent and young adult (AYA) patients in consultations when a diagnosis of cancer is delivered. Here, we investigated the content of such concerns and how health care providers respond to them. METHOD: We audio-recorded nine consultations with AYA cancer patients (ages: 12-25 years) at the time of diagnosis. We have previously identified and coded 135 emotional concerns and the responses to these in the nine consultations using the Verona Coding Definitions of Emotional Sequences (VR-CoDES) framework...
February 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28065210/prevalence-of-tuberculosis-infection-in-healthcare-workers-of-the-public-hospital-network-in-medell%C3%A3-n-colombia-a-bayesian-approach
#13
J Ochoa, A L León, I C Ramírez, C M Lopera, E Bernal, M P Arbeláez
A latent tuberculosis infection (LTBI) prevalence survey was conducted using tuberculin skin test (TST) and Quantiferon test (QFT) in 1218 healthcare workers (HCWs) in Medellín, Colombia. In order to improve the prevalence estimates, a latent class model was built using a Bayesian approach with informative priors on the sensitivity and specificity of the TST. The proportion of concordant results (TST+,QFT+) was 41% and the discordant results contributed 27%. The marginal estimate of the prevalence P(LTBI+) was 62·1% [95% credible interval (CrI) 53·0-68·2]...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28062427/novel-sleep-management-method-in-a-toddler-displaying-fear-and-trauma-the-boss-of-my-sleep-book
#14
Sarah Blunden
Sleep problems in toddlers occur in ∼40% of children and increase the likelihood of postnatal depression. Most sleep training in toddlers requires contact with a trained professional, and requires a parent to ignore their child's cries, causing distress to many children and parents, increasing attrition and leaving families untreated and at risk. This case study reports success in significantly ameliorating sleep reluctance and bedtime fears in a sleep disturbed toddler with a history of trauma. It uses a novel use of bedtime behaviour management with some positive reinforcement techniques, called the Boss of My Sleep book: a non-cry, online (thus readily and cheaply available without a trained professional) sleep intervention...
January 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28059619/comparison-of-iatrogenic-pain-between-rotavirus-vaccination-before-and-after-vaccine-injection-in-2-month-old-infants
#15
Hui-Chu Yin, Whei-Mei Shih, Hsiu-Lan Lee, Huei-Jing Yang, Yu-Li Chen, Shao-Wen Cheng, Chun-Yuh Yang, Ya-Wen Chiu, Yi-Hao Weng
Oral rotavirus vaccine (RV) administration in conjunction with other injectable vaccines has been used worldwide. However, whether the sequence of RV administration is associated with the reduction of injection-induced pain remains unclear. In this randomized controlled trial, we enrolled 6-12-wk-old healthy infants. The pain response of the infants was scored on the basis of their crying, irritability, facial expression, gagging and distress. A multivariate logistic regression model was used to compare the pain response after adjustment for possible confounders...
January 6, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28059319/structural-optimization-for-remote-white-light-emitting-diodes-with-quantum-dots-and-phosphor-packaging-sequence-matters
#16
Bin Xie, Wei Chen, Junjie Hao, Dan Wu, Xingjian Yu, Yanhua Chen, Run Hu, Kai Wang, Xiaobing Luo
White light-emitting diodes (WLEDs) with quantum dots (QDs) and phosphor have attracted tremendous attentions due to their excellent color rendering ability. In the packaging process, QDs layer and phosphor-silicone layer tend to be separated to reduce the reabsorption losses, and to maintain the stability of QDs surface ligands. This study investigated the packaging sequence between QDs and phosphor on the optical and thermal performances of WLEDs. The output optical power and PL spectra were measured and analyzed, and the temperature fields were simulated and validated experimentally by infrared thermal imager...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28051876/efficacy-of-breastfeeding-on-babies-pain-during-vaccinations
#17
Münevver Erkul, Emine Efe
OBJECTIVE: The aim of this randomized controlled experimental study was to evaluate the effect of breastfeeding on the pain of babies during vaccination. MATERIALS AND METHODS: The sample of the study consisted of 100 babies who complied with the sampling criteria between July and November 2012. The babies breastfed from their mothers 5 minutes before, during, and after the vaccine injections. The Neonatal Infant Pain Scale (NIPS), duration of crying, heart rate, and oxygen saturation were evaluated before, during, and after the vaccine injections...
January 4, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28050027/a-newly-recognized-association-of-hirschsprung-disease-with-cri-du-chat-syndrome
#18
Imdad Ullah, Lori Mahajan, David Magnuson
No abstract text is available yet for this article.
January 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28046020/response-to-infant-cry-in-clinically-depressed-and-non-depressed-mothers
#19
Gianluca Esposito, Nanmathi Manian, Anna Truzzi, Marc H Bornstein
BACKGROUND: Bowlby and Ainsworth hypothesized that maternal responsiveness is displayed in the context of infant distress. Depressed mothers are less responsive to infant distress vocalizations (cry) than non-depressed mothers. The present study focuses on acoustical components of infant cry that give rise to responsive caregiving in clinically depressed (n = 30) compared with non-depressed mothers (n = 30) in the natural setting of the home. METHODS: Analyses of infant and mother behaviors followed three paths: (1) tests of group differences in acoustic characteristics of infant cry, (2) tests of group differences of mothers' behaviors during their infant's crying, and (3) tree-based modeling to ascertain which variable(s) best predict maternal behaviors during infant cry...
2017: PloS One
https://www.readbyqxmd.com/read/28045886/the-effects-of-kangaroo-care-on-the-sleep-and-wake-states-of-preterm-infants
#20
Farideh Bastani, Nahid Rajai, Zahra Farsi, Heidelise Als
BACKGROUND: Developing interventions that improve deep sleep and quit awake is important to improve the quality of care that is provided to preterm infants. PURPOSE: The aim of this study was to compare the effects of kangaroo care and in-arms-holding on the sleep and wake states of preterm infants. METHODS: A randomized controlled trial design was employed in 2011-2012. Seventy-two stable preterm infants with gestational ages of 32-37 weeks and their mothers were recruited from the neonatal intensive care unit of Valiasr Hospital in Tehran, Iran...
December 29, 2016: Journal of Nursing Research: JNR
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