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https://www.readbyqxmd.com/read/29338487/acupuncture-treatments-for-infantile-colic-a-systematic-review-and-individual-patient-data-meta-analysis-of-blinding-test-validated-randomised-controlled-trials
#1
Holgeir Skjeie, Trygve Skonnord, Mette Brekke, Atle Klovning, Arne Fetveit, Kajsa Landgren, Inger Kristensson Hallström, Kjetil Gundro Brurberg
OBJECTIVE: Needle acupuncture in small children has gained some acceptance in Western medicine. It is controversial, as infants and toddlers are unable to consent to treatment. We aimed to assess its efficacy for treating infantile colic. DESIGN: A systematic review and a blinding-test validation based on individual patient data from randomised controlled trials. Primary end-points were crying time at mid-treatment, at the end of treatment and at a 1-month follow-up...
January 17, 2018: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/29335405/author-correction-myoblasts-and-macrophages-are-required-for-therapeutic-morpholino-antisense-oligonucleotide-delivery-to-dystrophic-muscle
#2
James S Novak, Marshall W Hogarth, Jessica F Boehler, Marie Nearing, Maria C Vila, Raul Heredia, Alyson A Fiorillo, Aiping Zhang, Yetrib Hathout, Eric P Hoffman, Jyoti K Jaiswal, Kanneboyina Nagaraju, Sebahattin Cirak, Terence A Partridge
In the original version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to include support from the CRI Light Microscopy and Image Analysis Core.
January 15, 2018: Nature Communications
https://www.readbyqxmd.com/read/29335023/early-neonatal-glutaric-aciduria-type-i-hidden-by-perinatal-asphyxia-a-case-report
#3
Giacomo Biasucci, Nicola Morelli, Federica Natacci, Massimo Mastrangelo
BACKGROUND: Perinatal asphyxia (PA) occurs in about 2 to 10 per 1000 live full-term births. Although neonatal epileptic seizures are observed in up to 60% of cases, PA may mimic or subtend other conditions. Hypoxia related brain injury is particularly relevant, as it may have permanent effects on neuropsychomotor development. Antepartum obstetric conditions, may, in turn, lead to hypoxic-ischemic damage to the fetus and the newborn, often underlying PA. Herein, a case of PA that hid and triggered signs and symptoms of Glutaric Aciduria type I (GA-I), is reported...
January 15, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29334914/-crying-without-tears-as-an-early-diagnostic-sign-post-of-triple-a-allgrove-syndrome-two-case-reports
#4
Daniel Tibussek, Sujal Ghosh, Angela Huebner, Joerg Schaper, Ertan Mayatepek, Katrin Koehler
BACKGROUND: Triple A syndrome (or Allgrove syndrome) is a rare autosomal recessive disorder characterized by alacrima, achalasia, adrenal insufficiency and autonomic/neurological abnormalities. The majority of cases are caused by mutations in the AAAS gene located on chromosome 12q13. However, the clinical picture as well as genetic testing may be complex since symptomatology is variable and mutations cannot be identified in all clinically diagnosed patients. We present two unrelated patients with triple-A syndrome illustrating the importance of alacrima as an early clinical sign...
January 15, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29334136/a-bayesian-network-meta-analysis-efficacy-of-air-insufflation-co2-insufflation-water-exchange-and-water-immersion-in-colonoscopy
#5
REVIEW
Zhen Zhang, Yifeng Wu, Guangge Sun, Jing Zhang, Jiaxin Li, Chongyang Qiu, Xin Zheng, Botao Wang, Lei Yang, Ximo Wang
BACKGROUND: Colonoscopy is one of the excellent tools for screening colorectal cancer. There were four colonoscopy techniques containing air insufflation, CO2 insufflation, water exchange, and water immersion. Some studies reported that these methods are better than the criterion standard (air insufflation), while some studies showed not. In order to evaluate the efficacy of four colonoscopy techniques, a network meta-analysis was performed in present study. METHODS: We searched randomized controlled trials (RCTs) published up to September 2017 from PubMed, Embase, Cochrane library, and Web of Science...
January 15, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29331033/the-efficacy-and-safety-comparison-of-surgical-treatments-for-stress-urinary-incontinence-a-network-meta-analysis
#6
REVIEW
Pan Song, Yibo Wen, Chuiguo Huang, Wancong Wang, Naijun Yuan, Yinliang Lu, Qingwei Wang, Tao Zhang, Jianguo Wen
AIMS: Stress urinary incontinence (SUI) is a common problem worldwide. Mainstream surgical procedures include tension-free vaginal tape (TVT), transobturator tape (TOT), tension-free vaginal tape-obturator (TVT-O), tension-free vaginal tape SECUR (TVT-S), and adjustable single-incision sling (Ajust). The aim of this study was to compare the efficacy and safety of these surgical procedures and assess which surgery is most optimal for SUI by adopting a network meta-analysis (NMA). METHODS: Electronic databases including PubMed, Cochrance Library, and Embase database were researched systematically, until March 21, 2017...
January 13, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29329169/differences-in-immunization-site-pain-in-toddlers-vaccinated-with-either-the-10-or-the-13-valent-pneumococcal-conjugate-vaccine
#7
Johannes Trück, Sarah Kelly, Sena Jawad, Matthew D Snape, Merryn Voysey, Andrew J Pollard
We investigated immediate immunization pain in 12-month-old children randomized to receive a booster dose of either the 10- (PCV-10) or the 13-valent (PCV-13) pneumococcal conjugate vaccine. Pain was assessed using validated pain assessment tools and crying time. PCV-13 recipients had significantly higher scores on the observer-rated modified behavioral pain scale than did those receiving PCV-10, but the differences were small.Clinical trial registration at Clinicaltrials.gov (NCT01443416).
January 10, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29327258/mental-health-problems-of-syrian-refugee-children-the-role-of-parental-factors
#8
Seyda Eruyar, John Maltby, Panos Vostanis
War-torn children are particularly vulnerable through direct trauma exposure as well through their parents' responses. This study thus investigated the association between trauma exposure and children's mental health, and the contribution of parent-related factors in this association. A cross-sectional study with 263 Syrian refugee children-parent dyads was conducted in Turkey. The Stressful Life Events Questionnaire (SLE), General Health Questionnaire, Parenting Stress Inventory (PSI-SF), Impact of Events Scale for Children (CRIES-8), and Strengths and Difficulties Questionnaire were used to measure trauma exposure, parental psychopathology, parenting-related stress, children's post-traumatic stress symptoms (PTSS), and mental health problems, respectively...
January 11, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29324423/effects-of-omega-3-fatty-acids-against-chemotherapy-induced-mucositis-a-double-blind-randomized-clinical-trial
#9
Maryam Alsadat Hashemipour, Samaneh Barzegari, Shahla Kakoie, Raha Habib Aghahi
OBJECTIVE: This double-blind randomized clinical trial evaluates the ef cacy and route of administration of omega-3 fatty acids for the prevention and treatment of oral mucositis in patients undergoing che- motherapy in Iranian hospitals. MATERIALS AND METHODS: Sixty patients developing World Health Organization (WHO) grade 1 oral mucositis were randomized to the omega-3 fatty acid (n=30) or placebo (n=30) group. Mucositis was assessed according to the WHO, Western Consortium for Cancer Nursing Research, and Oral Mucositis Weekly Questionnaire cri- teria at baseline and rst, second, and third weeks of chemotherapy un- til mucositis resolved...
December 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29323688/preventing-hiv-infection-what-pediatricians-should-know-about-hiv-pre-exposure-prophylaxis
#10
Sabrina Fernandez
I recently diagnosed my first adolescent patient with new-onset HIV. As a primary care pediatrician, these cases are rare. I cried with the shock of the initial diagnosis, just as the patient did when I told him. One of my first thoughts was how could I have served him better. He had been inconsistent with condom use, and had several partners. I had encouraged safe sex practices, told him to talk to his partners about pregnancy prevention, and screened for sexually transmitted disease nearly every time he came into my office...
January 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29323268/evaluation-of-animal-to-human-and-human-to-human-transmission-of-influenza-a-h7n9-virus-in-china-2013-15
#11
Victor Virlogeux, Luzhao Feng, Tim K Tsang, Hui Jiang, Vicky J Fang, Ying Qin, Peng Wu, Xiling Wang, Jiandong Zheng, Eric H Y Lau, Zhibin Peng, Juan Yang, Benjamin J Cowling, Hongjie Yu
A novel avian-origin influenza A(H7N9) virus emerged in China in March 2013 and by 27 September 2017 a total of 1533 laboratory-confirmed cases have been reported. Occurrences of animal-to-human and human-to-human transmission have been previously identified, and the force of human-to-human transmission is an important component of risk assessment. In this study, we constructed an ecological model to evaluate the animal-to-human and human-to-human transmission of H7N9 during the first three epidemic waves in spring 2013, winter/spring 2013-2014 and winter/spring 2014-2015 in China based on 149 laboratory-confirmed urban cases...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29317013/development-of-materials-to-support-parents-whose-babies-cry-excessively-findings-and-health-service-implications
#12
Jaqui Long, Charlotte Powell, Deborah Bamber, Rosemary Garratt, Jayne Brown, Sue Dyson, Ian St James-Roberts
Aim To develop evidence-based materials which provide information and support for parents who are concerned about their baby's excessive crying. As well as meeting these parents' needs, the aim was to develop a package of materials suitable for use by the UK National Health Service (NHS). BACKGROUND: Parents report that around 20% of infants in Western countries cry excessively without an apparent reason during the first four months of age. Traditionally, research has focused on the crying and its causes...
January 10, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29311535/the-medicinal-usage-and-restriction-of-ginseng-in-britain-and-america-1660-1900
#13
Heasim Sul
This article demonstrates the medicinal usage of ginseng in the West from 1660 to 1914. Asian[Korea] ginseng was first introduced into England in the early 17th century, and North American ginseng was found in the early 18th century. Starting from the late 17th century doctors prescribed ginseng to cure many different kinds of ailments and disease such as: fatigue general lethargy, fever, torpidity, trembling in the joints, nervous disorder, laughing and crying hysteria, scurvy, spermatic vessel infection, jaundice, leprosy, dry gripes and constipation, strangury, yellow fever, dysentery, infertility and addictions of alcohol, opium and tobacco, etc...
December 2017: Ŭi Sahak
https://www.readbyqxmd.com/read/29307054/lethal-and-sublethal-effects-of-the-herbicide-atrazine-in-the-early-stages-of-development-of-physalaemus-gracilis-anura-leptodactylidae
#14
Camila F Rutkoski, Natani Macagnan, Cassiane Kolcenti, Guilherme V Vanzetto, Paola F Sturza, Paulo A Hartmann, Marilia T Hartmann
Water sources used as reproductive sites by crying frog, Physalaemus gracilis, are extensively associated with agroecosystems in which the herbicide atrazine is employed. To evaluate the lethal and sublethal effects of atrazine commercial formulation, acute and chronic toxicity tests were performed in the embryonic phase and the beginning of the larval phase of P. gracilis. Tests were started on stage 19 of Gosner (Herpetologica 16:183-190, 1960) and performed in 24-well cell culture plates. Acute tests had a duration of 96 h with embryo mortality monitoring every 24 h...
January 6, 2018: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29304833/a-phase-i-study-of-selinexor-in-combination-with-high-dose-cytarabine-and-mitoxantrone-for-remission-induction-in-patients-with-acute-myeloid-leukemia
#15
Amy Y Wang, Howard Weiner, Margaret Green, Hua Chang, Noreen Fulton, Richard A Larson, Olatoyosi Odenike, Andrew S Artz, Michael R Bishop, Lucy A Godley, Michael J Thirman, Satyajit Kosuri, Jane E Churpek, Emily Curran, Kristen Pettit, Wendy Stock, Hongtao Liu
BACKGROUND: Novel therapies for patients with acute myeloid leukemia (AML) are imperative, particularly for those with high-risk features. Selinexor, an exportin 1 (XPO1/CRM1) inhibitor, has demonstrated anti-leukemia activity as a single agent, as well as in combination with anthracyclines and/or DNA-damaging agents. METHODS: We report the findings of a phase I dose escalation trial with cohort expansion in 20 patients with newly diagnosed or relapsed/refractory AML that combined selinexor with age-adjusted high-dose cytarabine and mitoxantrone (HiDAC/Mito)...
January 5, 2018: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/29303237/president-s-page-there-is-no-crying-in-baseball
#16
Kevin E Taubman
No abstract text is available yet for this article.
April 2017: Journal of the Oklahoma State Medical Association
https://www.readbyqxmd.com/read/29303036/cognitive-reserve-cognition-and-regional-brain-damage-in-ms-a-2%C3%A2-year-longitudinal-study
#17
Maria Assunta Rocca, Gianna C Riccitelli, Alessandro Meani, Elisabetta Pagani, Paola Del Sette, Vittorio Martinelli, Giancarlo Comi, Andrea Falini, Massimo Filippi
BACKGROUND: According to the cognitive reserve (CR) theory, enriching experiences protect against cognitive decline. OBJECTIVES: To investigate the dynamic interaction between CR and global/regional measures of brain white matter (WM) and gray matter (GM) damage and their effect on cognitive performance in multiple sclerosis (MS). METHODS: Baseline and 2 -year three-dimensional (3D) T1-weighted scans were obtained from 54 MS patients and 20 healthy controls...
January 1, 2018: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29301586/effectiveness-of-a-psycho-educational-intervention-to-prevent-postpartum-parental-distress-and-enhance-infant-well-being-study-protocol-of-a-randomized-controlled-trial
#18
Marjolein Missler, Roseriet Beijers, Jaap Denissen, Annemieke van Straten
BACKGROUND: The first months after birth can be challenging for parents, leading to parental distress and decreased well-being. Parents with high levels of distress are found to respond less adequately and sensitively to their infant, which in turn affects infant well-being and health. The goal of this study is to examine the effectiveness of a psycho-educational intervention to prevent postpartum parental distress and enhance the quality of caregiving and infant well-being. In contrast to other interventions, this intervention will be (1) offered already before birth, (2) offered to all parents-to-be, regardless of their risk of postpartum distress, and (3) include fathers...
January 4, 2018: Trials
https://www.readbyqxmd.com/read/29301546/spatial-and-temporal-patterns-of-dengue-infections-in-timor-leste-2005-2013
#19
Kinley Wangdi, Archie C A Clements, Tai Du, Susana Vaz Nery
BACKGROUND: Dengue remains an important public health problem in Timor-Leste, with several major epidemics occurring over the last 10 years. The aim of this study was to identify dengue clusters at high geographical resolution and to determine the association between local environmental characteristics and the distribution and transmission of the disease. METHODS: Notifications of dengue cases that occurred from January 2005 to December 2013 were obtained from the Ministry of Health, Timor-Leste...
January 4, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29300197/effectiveness-of-sucrose-used-routinely-for-pain-relief-and-neonatal-clinical-risk-in-preterm-infants-a-nonrandomized-study
#20
Beatriz Oliveira Valeri, Cláudia Maria Gaspardo, Francisco Eulógio Martinez, Maria Beatriz Martins Linhares
BACKGROUND: Preterm infants (PI) requiring the Neonatal Intensive Care Unit (NICU) are exposed to early repetitive pain/distress. Little is known about how pain relief strategies interact with infants'clinical health status, such as severity of illness with pain responses. This study aimed to examine main and interactive effects of routine sucrose intervention and neonatal clinical risk (NCR) on biobehavioral pain reactivity-recovery in PI during painful blood collection procedures. METHODS: Very-low birthweight PI (n=104) were assigned to Low and High Clinical Risk Groups, according to the Clinical Risk Index for Babies...
January 3, 2018: Clinical Journal of Pain
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