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Activated charcoal

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https://www.readbyqxmd.com/read/28535126/activated-charcoal-significantly-reduces-the-amount-of-colchicine-released-from-gloriosa-superba-in-simulated-gastric-and-intestinal-media
#1
Shukry Zawahir, Indika Gawarammana, Paul I Dargan, Mahfoudh Abdulghni, Andrew H Dawson
BACKGROUND: Poisoning with Gloriosa superba, a plant containing colchicine, is common in Sri Lanka. OBJECTIVES: This study was to estimate release of colchicine from 5 g of different parts of Gloriosa superba in simulated gastric and intestinal media, and examine the binding efficacy of activated charcoal (AC) to colchicine within this model. METHODS: A USP dissolution apparatus-II was used to prepare samples for analysis of colchicine using HPLC...
May 23, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28531860/boosting-biomethane-yield-and-production-rate-with-graphene-the-potential-of-direct-interspecies-electron-transfer-in-anaerobic-digestion
#2
Richen Lin, Jun Cheng, Jiabei Zhang, Junhu Zhou, Kefa Cen, Jerry D Murphy
Interspecies electron transfer between bacteria and archaea plays a vital role in enhancing energy efficiency of anaerobic digestion (AD). Conductive carbon materials (i.e. graphene nanomaterial and activated charcoal) were assessed to enhance AD of ethanol (a key intermediate product after acidogenesis of algae). The addition of graphene (1.0g/L) resulted in the highest biomethane yield (695.0±9.1mL/g) and production rate (95.7±7.6mL/g/d), corresponding to an enhancement of 25.0% in biomethane yield and 19...
May 5, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28497785/charcoal-evidence-that-rising-atmospheric-oxygen-terminated-early-jurassic-ocean-anoxia
#3
Sarah J Baker, Stephen P Hesselbo, Timothy M Lenton, Luís V Duarte, Claire M Belcher
The Toarcian Oceanic Anoxic Event (T-OAE) was characterized by a major disturbance to the global carbon(C)-cycle, and depleted oxygen in Earth's oceans resulting in marine mass extinction. Numerical models predict that increased organic carbon burial should drive a rise in atmospheric oxygen (pO2) leading to termination of an OAE after ∼1 Myr. Wildfire is highly responsive to changes in pO2 implying that fire-activity should vary across OAEs. Here we test this hypothesis by tracing variations in the abundance of fossil charcoal across the T-OAE...
May 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/28496040/induction-of-human-cytochrome-p450-3a-enzymes-in-cultured-placental-cells-by-thalidomide-and-relevance-to-bioactivation-and-toxicity
#4
Norie Murayama, Yasuhiro Kazuki, Daisuke Satoh, Kazuya Arata, Tasuku Harada, Norio Shibata, F Peter Guengerich, Hiroshi Yamazaki
Evidence has been presented for auto-induced human cytochrome P450 3A enzyme involvement in the teratogenicity and clinical outcome of thalidomide due to oxidation to 5-hydroxythalidomide and subsequent metabolic activation in livers. In this study, more relevant human placenta preparations and placental BeWo cells showed low but detectable P450 3A4/5 mRNA expression and drug oxidation activities. Human placental microsomal fractions from three subjects showed detectable midazolam 1´- and 4-hydroxylation and thalidomide 5-hydroxylation activities...
2017: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/28482318/differential-responses-of-peach-prunus-persica-seedlings-to-elevated-ozone-are-related-with-leaf-mass-per-area-antioxidant-enzymes-activity-rather-than-stomatal-conductance
#5
Lulu Dai, Pin Li, Bo Shang, Shuo Liu, Aizhen Yang, Younian Wang, Zhaozhong Feng
To evaluate the ozone (O3) sensitivity among peach tree (Prunus persica) cultivars widely planted in Beijing region and explore the possible eco-physiological response mechanisms, thirteen cultivars of peach seedlings were exposed to either charcoal-filtered air or elevated O3 (E-O3, non-filtered ambient air plus 60 ppb) for one growing season in open-top chambers. Leaf structure, stomatal structure, gas exchange and chlorophyll a fluorescence, photosynthetic pigments, antioxidant defense system and lipid peroxidation were measured in three replicated chambers...
May 5, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28474218/new-insight-into-sugarcane-industry-waste-utilization-press-mud-for-cleaner-biobutanol-production-by-using-c-acetobutylicum-nrrl-b-527
#6
Pranhita R Nimbalkar, Manisha A Khedkar, Shashank G Gaikwad, Prakash V Chavan, Sandip B Bankar
In the present study, press mud, a sugar industry waste, was explored for biobutanol production to strengthen agricultural economy. The fermentative production of biobutanol was investigated via series of steps, viz. characterization, drying, acid hydrolysis, detoxification, and fermentation. Press mud contains an adequate amount of cellulose (22.3%) and hemicellulose (21.67%) on dry basis, and hence, it can be utilized for further acetone-butanol-ethanol (ABE) production. Drying experiments were conducted in the temperature range of 60-120 °C to circumvent microbial spoilage and enhance storability of press mud...
May 5, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28472745/the-temperature-dependence-of-adsorption-coefficients-of-222-rn-on-activated-charcoal-an-experimental-study
#7
Lu Guo, Yunxiang Wang, Lei Zhang, Zhi Zeng, Wenbin Dong, Qiuju Guo
The radon adsorption coefficient of activated charcoal (K) has exponential relationship with temperature theoretically, but few experiment results of K at temperature below 0 ℃ were given. In this study, K were measured using a flow-through system with activated charcoal in cylindrical adsorption beds at temperature adjusted from room temperature to -48°C using liquid nitrogen. Results are consistent with theory and show that the adsorption coefficient at -48°C is nearly 25 times higher than that at 23 ℃...
April 20, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28472561/effect-of-steroid-and-serum-starvation-on-a-human-breast-cancer-adenocarcinoma-cell-line
#8
Maryam Nakhjavani, David J Stewart, Farshad H Shirazi
Breast cancer is one of the most frequent cancers in women. Although there are many treatment protocols for this disease, there are still many patients who do not respond satisfactorily to the current treatment protocols. A better understanding of the nature of the tumor cells might provide a guide for better therapeutic procedures. In this study, the effect of metabolic stress was assessed on the human adenocarcinoma MCF-7 cell line. The cells were seeded in culture plates and after reaching log phase of their growth, cells were exposed to phenol red free-media supplemented with 10%, 0...
May 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28448597/reconstructing-grassland-fire-history-using-sedimentary-charcoal-considering-count-size-and-shape
#9
Berangere A Leys, Julie L Commerford, Kendra K McLauchlan
Fire is a key Earth system process, with 80% of annual fire activity taking place in grassland areas. However, past fire regimes in grassland systems have been difficult to quantify due to challenges in interpreting the charcoal signal in depositional environments. To improve reconstructions of grassland fire regimes, it is essential to assess two key traits: (1) charcoal count, and (2) charcoal shape. In this study, we quantified the number of charcoal pieces in 51 sediment samples of ponds in the Great Plains and tested its relevance as a proxy for the fire regime by examining 13 potential factors influencing charcoal count, including various fire regime components (e...
2017: PloS One
https://www.readbyqxmd.com/read/28445845/the-capacity-and-effectiveness-of-diosmectite-and-charcoal-in-trapping-the-compounds-causing-the-most-frequent-intoxications-in-acute-medicine-a-comparative-study
#10
Michaela Mináriková, Veronika Fojtikova, Eliška Vyskočilová, Jan Sedláček, Milan Šikut, Lucie Borek-Dohalska, Marie Stiborová, Marketa Martinkova
The aim of the study was to compare the adsorption ability of two adsorbent materials, namely diosmectite and activated charcoal towards selected model compounds that are most commonly involved in acute intoxication. Eleven model compounds were selected: acetylsalicylic acid, α-amanitin, amlodipine, digoxin, phenobarbital, ibuprofen, imipramine, carbamazepine, oxazepam, promethazine, and theophylline. Of the tested compounds, promethazine and imipramine were the most effectively adsorbed to diosmectite. Their adsorption to diosmectite (0...
April 17, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28444601/somatic-embryogenesis-from-bud-and-leaf-explants-of-date-palm-phoenix-dactylifera-l-cv-najda
#11
Mouaad Amine Mazri, Ilham Belkoura, Reda Meziani, Boutaïna Mokhless, Souad Nour
An efficient regeneration system through somatic embryogenesis was developed for date palm cv. Najda. Adventitious bud and proximal leaf segments cultured on Murashige and Skoog (MS) medium supplemented with various combinations of auxins and cytokinins induced embryogenesis after at least 6 months of culture. Somatic embryogenesis induction seemed correlated with the type of the explant, the induction period and the auxin used. The highest rate of somatic embryogenesis (86.0%) was obtained on bud explants cultured on MS medium supplemented with 45...
May 2017: 3 Biotech
https://www.readbyqxmd.com/read/28441624/various-soil-amendments-and-environmental-wastes-affect-the-im-mobilization-and-phytoavailability-of-potentially-toxic-elements-in-a-sewage-effluent-irrigated-sandy-soil
#12
Sabry M Shaheen, Mohamed S Shams, Mohamed R Khalifa, Mohamed A El-Dali, Jörg Rinklebe
Contamination of long-term sewage effluent irrigated soils by potentially toxic elements (PTEs) is a serious concern due to its high environmental and health risk. Our scientific hypothesis is that soil amendments can cause contradictory effects on the element mobilization and phytoavailability depending on the type of element and amendment. Therefore, we aimed to assess the impact of the application (1%) of several low cost amendments and environmental wastes on the (im)mobilization, availability, and uptake of Al, Cd, Cr, Cu, Fe, Mn, Ni, and Zn by sorghum (Sorghum bicolor) in a long term sewage effluent irrigated sandy soils collected from Egypt...
August 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28429198/managing-the-perioperative-patient-on-direct-oral-anticoagulants
#13
Jordan Leitch, Janet van Vlymen
PURPOSE: Patients are increasingly treated with direct oral anticoagulants (DOACs) for the prevention of stroke due to non-valvular atrial fibrillation and for the treatment of venous thromboembolism. When these patients present for urgent or emergent surgical procedures, they present a challenge to the anesthesiologist who must manage perioperative risk due to anticoagulation. The purpose of this module is to review the literature surrounding the perioperative management of DOACs. Timing, laboratory monitoring, and availability of reversal agents are important considerations to optimize patients being treated with DOACs who require emergent surgery...
June 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28427112/acute-encephalopathy-in-a-2-year-old-pot-bellied-pig-following-accidental-intoxication-with-clonazepam
#14
Emilie L Setlakwe, Amy L Johnson
OBJECTIVE: To describe a case of successful management of clonazepam toxicity causing encephalopathy in a pot-bellied pig. CASE SUMMARY: A 2-year-old female pot-bellied pig weighing 13.5 kg was presented for evaluation of clinical signs of acute encephalopathy. Based on the animal's history and clinical signs, a tentative diagnosis of benzodiazepine (BZP) intoxication was made. The results of a urinary drug screening test designed to detect illicit substances in human urine indicated benzodiazepine exposure...
May 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28425455/the-effect-of-hydraulic-flowback-and-produced-water-on-gill-morphology-oxidative-stress-and-antioxidant-response-in-rainbow-trout-oncorhynchus-mykiss
#15
Tamzin A Blewett, Alyssa M Weinrauch, Perrine L M Delompré, Greg G Goss
Hydraulic fracturing fluid are complex mixtures containing high concentrations of salts (up to 330,000 ppm), organic, and metal contaminants. However, little data exist on the potential mechanisms of toxicity of these flowback and produced wastewaters (FPW) on aquatic biota. Juvenile rainbow trout were exposed to either control, FPW (2.5 or 7.5%), FPW that had been treated with activated charcoal (AC), or a custom salt-matched control (SW; replicating only the salt content of FPW) for 48 hours. Gill histology revealed decreases in interlamellar cell mass (ILCM) and mean lamellar length in all treatments (FPW, AC and SW) compared to control, indicative of hyperosmotic stress...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28413934/commonly-used-air-filters-fail-to-eliminate-secondhand-smoke-induced-oxidative-stress-and-inflammatory-responses
#16
Thivanka Muthumalage, Karen Pritsos, Kenneth Hunter, Chris Pritsos
Secondhand smoke (SHS) causes approximately 50,000 deaths per year. Despite all the health warnings, smoking is still allowed indoors in many states exposing both workers and patrons to SHS on a daily basis. The opponents of smoking bans suggest that present day air filtration systems remove the health hazards of exposure to SHS. In this study, using an acute SHS exposure model, we looked at the impact of commonly used air filters (MERV-8 pleated and MERV-8 pleated activated charcoal) on SHS by assessing the inflammatory response and the oxidative stress response in C57BL/6 mice...
May 5, 2017: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/28411425/thoron-mitigation-system-based-on-charcoal-bed-for-applications-in-thorium-fuel-cycle-facilities-part-1-development-of-theoretical-models-for-design-considerations
#17
B K Sahoo, K Sudeep Kumara, N Karunakara, J J Gaware, B K Sapra, Y S Mayya
Regulating the environmental discharge of (220)Rn (historically known as thoron) and its decay products from thorium processing facilities is important for protection of environment and general public living in the vicinities. Activated charcoal provides an effective solution to this problem because of its high adsorption capacity to gaseous element like radon. In order to design and develop a charcoal based Thoron Mitigation System, a mathematical model has been developed in the present work for studying the (220)Rn transport and adsorption in a flow through charcoal bed and estimating the (220)Rn mitigation factor (MF) as a function of system and operating parameters...
June 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28400780/overexpression-of-a-new-osmotin-like-protein-gene-sindolp-confers-tolerance-against-biotic-and-abiotic-stresses-in-sesame
#18
Supriyo Chowdhury, Arpita Basu, Surekha Kundu
Osmotin-like proteins (OLPs), of PR-5 family, mediate defense against abiotic, and biotic stresses in plants. Overexpression in sesame of an OLP gene (SindOLP), enhanced tolerance against drought, salinity, oxidative stress, and the charcoal rot pathogen. SindOLP was expressed in all parts and localized to the cytosol. The transgenic plants recovered after prolonged drought and salinity stress, showing less electrolyte leakage, more water content, longer roots, and smaller stomatal aperture compared to control plants...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28396325/metabolic-genetic-screens-reveal-multidimensional-regulation-of-virulence-gene-expression-in-listeria-monocytogenes-and-an-aminopeptidase-that-is-critical-for-prfa-protein-activation
#19
Sivan Friedman, Marika Linsky, Lior Lobel, Lev Rabinovich, Nadejda Sigal, Anat A Herskovits
Listeria monocytogenes is an environmental saprophyte and intracellular bacterial pathogen. Upon invading mammalian cells, the bacterium senses abrupt changes in its metabolic environment, which are rapidly transduced to regulation of virulence gene expression. To explore the relationship between L. monocytogenes metabolism and virulence, we monitored virulence gene expression dynamics across a library of genetic mutants grown under two metabolic conditions known to activate the virulent state: charcoal-treated rich medium containing glucose 1-phosphate and minimal defined medium containing limiting concentrations of branched-chain amino acids (BCAAs)...
April 10, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28383578/a-novel-electroluminescent-device-based-on-a-reduced-graphene-oxide-wrapped-phosphor-zns-cu-al-and-hexagonal-boron-nitride-for-high-performance-luminescence
#20
Bipin Kumar Gupta, Satbir Singh, Garima Kedawat, Kanika, Pawan Kumar, Amit Kumar Gangwar, Tharangattu N Narayanan, Angel A Marti, Robert Vajtai, P M Ajayan
Reduced graphene oxide (rGO) has recently emerged as a very promising family of exotic carbon material with augmented performance in electronic and optoelectronic devices. Herein, we report an efficient and novel inorganic electroluminescent device geometry, where a new phosphor composite, reduced graphene oxide wrapped ZnS:Cu,Al, acts as an active emitting layer and an exfoliated hexagonal boron nitride (h-BN) as a dielectric layer. The roles of rGO in the active layer as a conductive support and local electric field enhancing agent are attributed to its wrinkles being unraveled compared with other carbon exotic nano-forms such as carbon nanotubes, graphite, charcoal and activated carbon, which significantly improves the brightness of the device (∼50 cd m(-2) for 0...
April 6, 2017: Nanoscale
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