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https://www.readbyqxmd.com/read/29656624/health-care-burden-of-spinal-diseases-in-the-republic-of-korea-analysis-of-a-nationwide-database-from-2012-through-2016
#1
Chang-Hyun Lee, Chun Kee Chung, Chi Heon Kim, Ji-Woong Kwon
OBJECTIVE: This study aimed to determine the incidence and analyze trends related to spinal diseases based on a national database in the Republic of Korea (ROK) and to elucidate the healthcare burden that will serve as a useful resource for researchers, clinicians, and patients. METHODS: This study was a retrospective analysis of data obtained from Healthcare Bigdata Hub, the Korean Statistical Information Service, and Open Data Portal from 2012 through 2016. The main disease codes for spinal diseases (M40-M54) were used for identification of these conditions...
March 2018: Neurospine
https://www.readbyqxmd.com/read/29656469/mortality-and-nursing-home-placement-of-dementia-patients-in-rural-and-urban-areas-a-cohort-study-from-the-swedish-dementia-registry
#2
Mandy Roheger, Eva Zupanic, Ingemar Kåreholt, Dorota Religa, Elke Kalbe, Maria Eriksdotter, Sara Garcia-Ptacek
BACKGROUND: Life in rural and urban areas differs in regard to social support and health care. Our aim was to examine the association between nursing home placement and survival of patients with dementia living in urban vs. rural areas. METHODS: We performed a longitudinal cohort study of patients with dementia at time of diagnosis (n = 58 154) and at first follow-up (n = 21 522) including patients registered from 2007 through 2014 in the Swedish Dementia Registry (SveDem)...
April 14, 2018: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/29655818/risk-factors-and-clinical-outcomes-of-sinus-membrane-perforation-during-lateral-window-sinus-lifting-analysis-of-120-patients
#3
H C Tükel, U Tatli
The aim of this study was to identify the risk factors associated with sinus membrane perforation and the effect of sinus membrane perforation and other risk factors on graft success and postoperative sinusitis. Sinus membrane perforation, graft failure, and postoperative sinusitis were tested for an association with age, sex, operator experience, side of the operation, residual bone height, presence of septa, presence of a mucous retention cyst, and smoking (χ2 test). Logistic regression analysis was used to model the odds ratio (OR) with corresponding risk factors...
April 11, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29655776/association-between-dietary-inflammatory-index-and-hodgkin-s-lymphoma-in-an-italian-case-control-study
#4
Nitin Shivappa, James R Hébert, Martina Taborelli, Antonella Zucchetto, Maurizio Montella, Massimo Libra, Carlo La Vecchia, Diego Serraino, Jerry Polesel
OBJECTIVES: The components of a diet can modulate inflammation and may have an effect on the development of Hodgkin's lymphoma (HL). Little is known about the inflammatory potential of diet in relation to HL. METHODS: Data from an Italian multicenter case-control study that was conducted between 1992 and 2008 were used to estimate the relation between a dietary inflammatory index (DII® ) and the risk of HL. The data included 179 cases with incident, histologically confirmed HL and 186 control cases who were hospitalized for acute non-neoplastic diseases...
February 12, 2018: Nutrition
https://www.readbyqxmd.com/read/29653321/neurodevelopmental-comorbidities-and-seizure-control-24-months-after-a-first-unprovoked-seizure-in-children
#5
Eva Åndell, Torbjörn Tomson, Sofia Carlsson, Kristina Tedroff, Per Åmark
PURPOSE: To follow children with newly diagnosed unprovoked seizures to determine (1) whether the prevalence of neurodevelopmental comorbidities and cerebral palsy (CP) changed after the initial seizure, and (2) the association between studied comorbidities and seizures 13-24 months after seizure onset or initiation of treatment. METHODS: Analyses were based on 750 children (28 days-18 years) with a first unprovoked seizure (index) included in a population-based Incidence Registry in Stockholm between 2001 and 2006...
March 20, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29653272/evaluation-of-microsurgery-for-managing-giant-or-complex-cerebral-aneurysms-a-retrospective-study
#6
Nakao Ota, Hidetoshi Matsukawa, Kosumo Noda, Hirotaka Sato, Yuto Hatano, Atsumu Hashimoto, Takanori Miyazaki, Tomomasa Kondo, Yu Kinoshita, Norihiro Saito, Hiroyasu Kamiyama, Sadahisa Tokuda, Kyousuke Kamada, Rokuya Tanikawa
OBJECTS: Surgical or endovascular treatment for giant or complex aneurysms is challenging. To evaluate clinical outcomes and factors affecting the prognosis of giant or complex aneurysms, and to better establish the role of microsurgery in the management strategy. METHODS: One hundred fifty-nine patients with surgically treated complex aneurysms were included. Thirty-two (20.1%) patients had giant aneurysms (≥25 mm); 57 (35.8%) had large aneurysms (≥15 mm). Poor outcome was defined as modified Rankin scale scores 3-6...
April 10, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29653271/risk-factors-additional-length-of-stay-and-cost-associated-with-postoperative-ileus-following-anterior-lumbar-interbody-fusion-in-the-elderly
#7
Jason A Horowitz, Amit Jain, Varun Puvanesarajah, Rabia Qureshi, Hamid Hassanzadeh
OBJECTIVE: Identify the independent risk factors, additional length of stay, and additional cost associated with postoperative ileus following anterior lumbar interbody fusion in the elderly. METHODS: The PearlDiver Patient Records Database (Young & Ellison, LLC, Colorado Springs, CO) was queried for all Medicare patients 65 years of age and older undergoing 1 or 2 level primary elective anterior lumbar interbody fusion from 2005-2014. Independent risk factors, additional length of stay, and additional cost associated with postoperative ileus were evaluated with multivariate analysis...
April 10, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29653085/prognostic-significance-of-pre-resection-albumin-fibrinogen-ratio-in-patients-with-non-small-cell-lung-cancer-a-propensity-score-matching-analysis
#8
Shuaishuai Chen, Haixi Yan, Juping Du, Jun Li, Bo Shen, Haijian Ying, Ying Zhang, Shiyong Chen
BACKGROUND: Nutrition and coagulation play important roles in cancer progression. This study was aimed to investigate the value of the albumin/fibrinogen ratio (AFR) in non-small cell lung cancer (NSCLC) patients, through a propensity score matching (PSM) method. METHODS: We retrospectively analyzed 529 NSCLC patients underwent surgical resection from 2010 to 2015. PSM was used to eliminate possible biases. A Cox proportional hazards regression model was performed to evaluate the prognostic value of AFR in NSCLC...
April 10, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29653030/sex-modulates-the-association-of-fibroblast-growth-factor-21-with-end-stage-renal-disease-in-asian-people-with-type-2-diabetes-a-6-3-year-prospective-cohort-study
#9
Jian-Jun Liu, Sylvia Liu, Robin Wm Choo, Shiou Liang Wee, Aimin Xu, Su Chi Lim
AIM: To study whether plasma fibroblast growth factor 21 independently predicts the risk of end-stage renal disease in Asian people with Type 2 diabetes. METHODS: In this prospective cohort study, 1700 Asian people with Type 2 diabetes were followed for a mean of 6.3 years in a regional hospital in Singapore. Incident end-stage renal disease was identified by linkage with a national renal registry. The association of baseline fibroblast growth factor 21 levels with risk of progression to end-stage renal disease was studied using survival analyses...
April 13, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29652957/-impact-of-high-salt-consumption-of-blood-pressure-on-a-non-hypertensive-population
#10
Karen Domínguez Cancino, María Cristina Paredes Escobar
Background There is conflicting evidence regarding the role of salt intake in blood pressure (BP). Aim To estimate the impact of salt consumption on the BP level of a non-hypertensive population aged between 15 and 64 years. Material and Methods Analytical-observational study using data from the National Health Survey 2009-2010. A BP cut-off point at 120/80 mmHg BP was considered to determine risk. Salt consumption was divided into four strata. The prevalence ratios (PR) were determined using the Poisson model with robust variance...
December 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29652920/association-of-renal-hyperfiltration-with-incident-proteinuria-a-nationwide-registry-study
#11
Seung Min Lee, Ju-Young Park, Min-Su Park, Jong Heon Park, Minseon Park, Hyung-Jin Yoon
To elucidate the association between renal hyperfiltration (RHF) and incident proteinuria, the data from 11,559,520 Korean adults who had undergone health screenings ≥ 3 times between 2009 and 2014 and had glomerular filtration rate (GFR) ≥60 mL/min/1.73m2 and negative dipstick test for proteinuria at baseline, were retrospectively analyzed. GFR was estimated with the Chronic Kidney Disease Epidemiology Collaboration equation based on serum creatinine, and RHF was defined as GFR >95th percentile adjusted for sex, age, body size, and diabetes and/or hypertension medication...
2018: PloS One
https://www.readbyqxmd.com/read/29652898/tooth-loss-and-pneumonia-mortality-a-cohort-study-of-japanese-dentists
#12
Shino Suma, Mariko Naito, Kenji Wakai, Toru Naito, Masaaki Kojima, Osami Umemura, Makoto Yokota, Nobuhiro Hanada, Takashi Kawamura
Although associations between oral health and pneumonia have been reported in previous studies, particularly in the institutionalized elderly, few prospective studies have investigated the association between oral condition and pneumonia among community-dwelling people and whether the findings among inpatients or patients in nursing homes are applicable to the general population is still unclear. The oral bacteria propagated in the periodontal regions may drop into the lung and increase the risk of pneumonia...
2018: PloS One
https://www.readbyqxmd.com/read/29652785/clinical-prediction-rule-for-heterotopic-ossification-of-the-hip-in-patients-with-spinal-cord-injury
#13
Eduardo M Suero, Mustafa Citak
STUDY DESIGN: Case-control study; clinical prediction rule. OBJECTIVE: To construct and internally validate a clinical prediction rule to identify patients at high risk of developing heterotopic ossification (HO) after spinal cord injury (SCI). SUMMARY OF BACKGROUND DATA: HO after SCI can lead to loss of joint mobility, loss of function, peripheral nerve entrapment, and pressure sores. HO is usually diagnosed based on clinical symptoms, as no laboratory tests are yet available to identify patients with early HO formation...
April 12, 2018: Spine
https://www.readbyqxmd.com/read/29652597/hypothyroidism-during-tyrosine-kinase-inhibitor-therapy-is-associated-with-longer-survival-in-patients-with-advanced-nonthyroidal-cancers
#14
Melissa G Lechner, Chirag M Vyas, Ole-Petter R Hamnvik, Erik K Alexander, P Reed Larsen, Toni K Choueiri, Trevor E Angell
BACKGROUND: Tyrosine kinase inhibitor (TKI)-induced thyroid dysfunction is recognized as a common adverse effect of treatment, but the importance of incident hypothyroidism during TKI therapy remains unclear. This study analyzed the prognostic significance of hypothyroidism during TKI therapy in cancer patients. METHODS: This was a retrospective cohort study of adult patients with advanced nonthyroidal cancer treated with TKI and available thyroid function testing at three affiliated academic hospitals from 2000 to 2017...
April 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29652308/-clinical-psychopathological-aspects-of-therapeutic-effects-of-agomelatine-valdoxan-and-its-place-in-perfection-of-methods-of-therapy-of-postschizophrenic-depressive-disorders
#15
G P Panteleyeva, L I Abramova, T E Novozhenova, N V Subbotskaya, D V Tikhonov, P E Yumatova, I Yu Nikiforova
AIM: To determine a therapeutic effect of agomelatine (valdoxan) on post-schizophrenic depression (PSD), taking into account its psychopathological structure. MATERIAL AND METHODS: A total of 33 patients of both sexes (average age was 32.1 yrs) with symptoms of post-schizophrenic depression (F20.4 according to ICD-10) were examined by using clinical and psychometric methods in the dynamics of shift-like schizophrenia. HAMD-17, PANSS and CGI-S scales were applied...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29652166/ambulance-use-distance-and-outcomes-in-patients-with-suspected-cardiovascular-disease-a-registry-based-geographic-information-system-study
#16
Nariman Sepehrvand, Wendimagegn Alemayehu, Padma Kaul, Rick Pelletier, Aminu K Bello, Robert C Welsh, Paul W Armstrong, Justin A Ezekowitz
BACKGROUND: Despite guideline recommendations, the majority of patients with symptoms suggestive of acute coronary syndrome do not use emergency medical services to reach the emergency department (ED). The aim of this study was to investigate the factors associated with EMS utilisation and subsequent patient outcomes. METHODS: Using administrative data, all patients who presented to an ED in the metropolitan areas of Edmonton and Calgary in the years of 2007-2013 with main ED diagnosis of acute coronary syndrome, stable angina or chest pain were included...
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29651409/incidence-of-comorbidities-in-women-with-breast-cancer-treated-with-tamoxifen-or-an-aromatase-inhibitor-an-australian-population-based-cohort-study
#17
Huah Shin Ng, Bogda Koczwara, David Roder, Theo Niyonsenga, Agnes Vitry
Background: The development of comorbidities has become increasingly relevant with longer-term cancer survival. Objective: To assess the pattern of comorbidities among Australian women with breast cancer treated with tamoxifen or an aromatase inhibitor. Design: Retrospective cohort study using Pharmaceutical Benefits Scheme (PBS) data (10% sample) from January 2003 to December 2014. Dispensing claims data were used to identify comorbidities and classified with the Rx-Risk-V model...
2018: Journal of Comorbidity
https://www.readbyqxmd.com/read/29650708/outcomes-in-asymptomatic-severe-aortic-stenosis-with-preserved-ejection-fraction-undergoing-rest-and-treadmill-stress-echocardiography
#18
Chetan P Huded, Ahmad Masri, Kenya Kusunose, Andrew L Goodman, Richard A Grimm, A Marc Gillinov, Douglas R Johnston, L Leonardo Rodriguez, Zoran B Popovic, Lars G Svensson, Brian P Griffin, Milind Y Desai
BACKGROUND: In asymptomatic patients with severe aortic stenosis and preserved left ventricular ejection fraction, we sought to assess the incremental prognostic value of resting valvuloarterial impedence (Zva) and left ventricular global longitudinal strain (LV-GLS) to treadmill stress echocardiography. METHODS AND RESULTS: We studied 504 such patients (66±12 years, 78% men, 32% with coronary artery disease who underwent treadmill stress echocardiography between 2001 and 2012...
April 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29650284/-home-non-invasive-ventilation-for-chronic-obstructive-pulmonary-disease
#19
S Toujani, S Dabboussi, H Snene, M Mjid, S Kamoun, A Hedhli, S Cheikh Rouhou, R Cheikh, M Beji, Y Ouahchi, J Cherif
INTRODUCTION: The benefits of long-term non-invasive ventilation (NIV) in the management of chronic obstructive pulmonary disease (COPD) patients remain controversial. AIM: To analyze the characteristics of COPD patients under home NIV and to evaluate its impact among this population. METHODS: We carried out a retrospective study between January 2002 and April 2016 of COPD patients under long-term NIV at "la Rabta" and the Military Hospital...
April 9, 2018: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/29650248/prevalence-and-risk-factors-of-chronic-obstructive-pulmonary-disease-in-china-the-china-pulmonary-health-cph-study-a-national-cross-sectional-study
#20
Chen Wang, Jianying Xu, Lan Yang, Yongjian Xu, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Kewu Huang, Wanzhen Yao, Tieying Sun, Guangliang Shan, Ting Yang, Yingxiang Lin, Sinan Wu, Jianguo Zhu, Ruiying Wang, Zhihong Shi, Jianping Zhao, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Yumin Zhou, Liren Ding, Ting Yang, Yahong Chen, Yanfei Guo, Fei Xiao, Yong Lu, Xiaoxia Peng, Biao Zhang, Dan Xiao, Chung-Shiuan Chen, Zuomin Wang, Hong Zhang, Xiaoning Bu, Xiaolei Zhang, Li An, Shu Zhang, Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Bin Cao, Huaping Dai, Lirong Liang, Jiang He
BACKGROUND: Although exposure to cigarette smoking and air pollution is common, the current prevalence of chronic obstructive pulmonary disease (COPD) is unknown in the Chinese adult population. We conducted the China Pulmonary Health (CPH) study to assess the prevalence and risk factors of COPD in China. METHODS: The CPH study is a cross-sectional study in a nationally representative sample of adults aged 20 years or older from ten provinces, autonomous regions, and municipalities in mainland China...
April 9, 2018: Lancet
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