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Morton Kern

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https://www.readbyqxmd.com/read/28924344/the-return-of-the-vulnerable-plaque-optical-coherence-tomography-imaging-of-a-case-of-a-late-in-stent-restenotic-chronic-total-occlusion
#1
Dilbahar S Mohar, Pranav M Patel, Alisha K Grewal, Prabhsimran Mohar, Morton J Kern
Although the use of drug-eluting stents (DES) has dramatically decreased the incidence of in-stent restenosis (ISR), concerns regarding the late manifestations of ISR remain. Optical coherence tomography (OCT) imaging provides unique insights into characteristics and patterns of ISR. We report a case of late DES ISR with unusual heterogeneous intracoronary luminal characteristics suggestive of vulnerable atherosclerotic plaque activity by OCT imaging. This case demonstrates that late ISR after DES may involve more than mere neointimal hyperplasia with lesion-associated craters, septae, and neoatherosclerosis...
September 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28805035/one-catheter-or-two-tomayto-or-tomahto
#2
EDITORIAL
Arnold H Seto, Morton J Kern
This retrospective study compares the performance of transradial diagnostic procedures using the single versus Judkins catheter approach. The Judkins approach had a 15% lower patient radiation exposure than single catheter approach while fluoroscopy time was comparable. Future studies of comparing such techniques may always be limited by operator preference, experience, and comfort.
August 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28666784/interpreting-results-of-coronary-computed-tomography-angiography-derived-fractional-flow-reserve-in-clinical-practice
#3
REVIEW
Mark G Rabbat, Daniel S Berman, Morton Kern, Gilbert Raff, Kavitha Chinnaiyan, Lynne Koweek, Leslee J Shaw, Philipp Blanke, Markus Scherer, Jesper M Jensen, John Lesser, Bjarne L Nørgaard, Gianluca Pontone, Bernard De Bruyne, Jeroen J Bax, Jonathon Leipsic
The application of computational fluid dynamics to coronary computed tomography angiography allows Fractional Flow Reserve (FFR) to be calculated non-invasively (FFRCT), enabling computation of FFR from coronary computed tomography angiography acquired at rest both for individual lesions as well as along the entire course of a coronary artery. FFRCT, validated in a number of accuracy studies and a large clinical utility trial, is beginning to penetrate clinical practice. Importantly, while accuracy trials compared FFRCT to invasively measured FFR at a single point in the coronary tree, clinical reports of FFRCT provide information regarding a patient's entire coronary vasculature...
June 23, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28600085/invasive-hemodynamics-of-myocardial-disease-systolic-and-diastolic-dysfunction-and-hypertrophic-obstructive-cardiomyopathy
#4
REVIEW
Michael Eskander, Morton J Kern
Heart failure is a clinical diagnosis that is supported by various laboratory, imaging, and invasive hemodynamic measures. There is no single diagnostic test. A variety of structural and/or functional myocardial abnormalities can lead to the inability of the heart to fill or eject blood. Despite ejection fraction being the most commonly assessed measure of systolic function in clinical practice, it is a poor measure of contractility because it is susceptible to loading conditions and chamber size. Invasive hemodynamic assessment remains of great importance in the evaluation of patients with myocardial disease or hypertrophic cardiomyopathy...
July 2017: Interventional cardiology clinics
https://www.readbyqxmd.com/read/28566293/stimulating-extracardiac-collaterals-via-right-internal-mammary-artery-occlusion-another-step-into-an-undiscovered-country
#5
EDITORIAL
Morton J Kern, Arnold H Seto
No abstract text is available yet for this article.
June 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28489331/scai-hfsa-clinical-expert-consensus-document-on-the-use-of-invasive-hemodynamics-for-the-diagnosis-and-management-of-cardiovascular-disease
#6
EDITORIAL
Paul Sorajja, Barry A Borlaug, Vasiliki V Dimas, James C Fang, Paul R Forfia, Michael M Givertz, Navin K Kapur, Morton J Kern, Srihari S Naidu
No abstract text is available yet for this article.
June 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28489324/executive-summary-of-the-scai-hfsa-clinical-expert-consensus-document-on-the-use-of-invasive-hemodynamics-for-the-diagnosis-and-management-of-cardiovascular-disease
#7
Paul Sorajja, Barry A Borlaug, Vivian Dimas, James C Fang, Paul R Forfia, Michael M Givertz, Navin K Kapur, Morton J Kern, Srihari S Naidu
No abstract text is available yet for this article.
June 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28454731/executive-summary-of-the-scai-hfsa-clinical-expert-consensus-document-on-the-use-of-invasive-hemodynamics-for-the-diagnosis-and-management-of-cardiovascular-disease
#8
Michael M Givertz, James C Fang, Paul Sorajja, Vivian Dimas, Paul R Forfia, Navin K Kapur, Morton J Kern, Srihari S Naidu, Barry A Borlaug
No abstract text is available yet for this article.
April 25, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28419792/breaking-the-code-what-is-the-best-post-pci-mi-definition
#9
EDITORIAL
Arnold H Seto, Morton J Kern
Various definitions of post-PCI MI have been recommended by different professional societies and studies. This present study suggests that the troponin-based 3rd universal definition of post-PCI MI has prognostic value for recurrent MI but not mortality alone, unlike the CK-MB based SCAI definition. Absent a consensus on the best definition, clinical trials should report outcomes based on multiple definitions of post-PCI MI.
April 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28206721/does-pre-pci-ffr-predict-post-pci-blood-flow-increase-do-we-need-imr-too
#10
EDITORIAL
Morton J Kern, Arnold H Seto
No abstract text is available yet for this article.
February 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28026741/comparing-hemodynamics-of-contemporary-mechanical-circulatory%C3%A2-support-moving-from-in-silico-to-in%C3%A2-vivo-results
#11
EDITORIAL
Morton J Kern, Arnold H Seto
No abstract text is available yet for this article.
November 28, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27884242/does-the-natural-history-of-atherosclerosis-follow-an-ischemic%C3%A2-dose-response-curve
#12
EDITORIAL
Arnold H Seto, Morton J Kern
No abstract text is available yet for this article.
November 29, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27865075/does-the-atomic-trial-explode-concerns-of-contrast-coagulopathy
#13
EDITORIAL
Arnold H Seto, Morton J Kern
No abstract text is available yet for this article.
November 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27667376/a-closer-look-at-fractional-flow-reserve-in-complex-anatomic-subsets-left-main-disease-bifurcation-lesions-and-saphenous-vein-grafts
#14
REVIEW
David C Lange, Morton J Kern
Fractional flow reserve (FFR) is a well-validated tool for determining the functional significance of a coronary artery stenosis, facilitating clinical decisions regarding the need for revascularization. FFR-guided revascularization improves clinical and economic outcomes. However, its application remains challenging in certain complex anatomic subsets, including left main coronary artery stenosis, bifurcation disease, and saphenous vein graft disease. This article reviews recent data supporting the use of FFR in these complex anatomic subsets...
2016: Reviews in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27566991/defining-the-common-femoral-artery-insights-from-the-femoral-arterial-access-with-ultrasound-trial
#15
Arnold H Seto, Jeffrey Tyler, William M Suh, Alexander T Harrison, Jesus A Vera, Soni J Zacharias, Timothy S Daly, Jeffrey M Sparling, Pranav M Patel, Morton J Kern, Mazen Abu-Fadel
OBJECTIVE: We sought to establish the typical location of the common femoral artery (CFA) bifurcation, the origin and most inferior reflection of the inferior epigastric artery (IEA) relative to the femoral head (FH) and whether patient demographics predicted anatomical variations. BACKGROUND: In the absence of ultrasound guidance or prior imaging, the precise location of the CFA bifurcation and IEA can only be determined following access site angiography. Fluoroscopic landmarks are commonly used to estimate the location of the CFA bifurcation, but the position of the IEA is less well characterized...
August 27, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27553817/my-approach-to-the-patient-diagnosed-with-significant-left-main-disease-use-of-ffr-ivus-and-oct
#16
Morton J Kern
No abstract text is available yet for this article.
October 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27515335/standardization-of-fractional%C3%A2-flow%C3%A2-reserve%C3%A2-measurements
#17
REVIEW
Gabor G Toth, Nils P Johnson, Allen Jeremias, Mariano Pellicano, Pascal Vranckx, William F Fearon, Emanuele Barbato, Morton J Kern, Nico H J Pijls, Bernard De Bruyne
Pressure wire-based fractional flow reserve is considered the standard of reference for evaluation of the ischemic potential of coronary stenoses and the expected benefit from revascularization. Accordingly, its application in daily practice or for research purposes has to be as standardized as possible to avoid technical or operator-related artifacts in pressure recordings. This document proposes a standardized way of acquiring, recording, interpreting, and archiving the pressure tracings for daily practice and for the purpose of clinical research involving a core laboratory...
August 16, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27511973/myocardial-contrast-stress-echo-versus-fractional-flow-reserve-a-fair-fight-among-ischemic-tests
#18
EDITORIAL
Morton J Kern, Arnold H Seto
No abstract text is available yet for this article.
August 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27410953/pci-in-failing-saphenous-vein-grafts-des-trumps-bms-for-the-older-patient
#19
EDITORIAL
Pranav M Patel, Morton J Kern
PCI to SVG is considered a higher risk intervention requiring clinical judgment, especially in the elderly who may have the oldest and most degenerated SVG conduits. In a cohort of patients with a median age of 75 years who received PCI to SVG with DES, all-cause mortality was lower compared to those receiving BMS, and no difference in MI or urgent revascularization was observed to 3 years. PCI to SVG using DES may be a viable and perhaps superior treatment option for elderly patients.
January 1, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27390334/prognostic-determinants-of-coronary-atherosclerosis-in-stable-ischemic-heart-disease-anatomy-physiology-or-morphology
#20
REVIEW
Amir Ahmadi, Gregg W Stone, Jonathon Leipsic, Leslee J Shaw, Todd C Villines, Morton J Kern, Harvey Hecht, David Erlinge, Ori Ben-Yehuda, Akiko Maehara, Eloisa Arbustini, Patrick Serruys, Hector M Garcia-Garcia, Jagat Narula
Risk stratification in patients with stable ischemic heart disease is essential to guide treatment decisions. In this regard, whether coronary anatomy, physiology, or plaque morphology is the best determinant of prognosis (and driver an effective therapeutic risk reduction) remains one of the greatest ongoing debates in cardiology. In the present report, we review the evidence for each of these characteristics and explore potential algorithms that may enable a practical diagnostic and therapeutic strategy for the management of patients with stable ischemic heart disease...
July 8, 2016: Circulation Research
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