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Ajay Kirtane

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https://www.readbyqxmd.com/read/27866130/outcomes-of-stenting-extra-small-%C3%A2-2-25-mm-vessels-using-the-resolute-zotarolimus-eluting-stent-r-zes
#1
Manish A Parikh, Jonathan Soverow, Martin B Leon, Patrick Serruys, Bo Xu, Zuyi Yuan, Robayaah Zambahari, Ajay Kirtane
AIMS: We assessed long-term outcomes in patients with extra-small (XS) (≤2.25 mm) and small vessels (SV) (>2.25-2.75 mm) treated with the Resolute zotarolimus-eluting stent (R-ZES). METHODS AND RESULTS: Data from eight studies including patients with XS or SV were pooled for this analysis. Among 2,141 patients (837 XS, 1,304 SV), three-year cumulative major adverse cardiac events (15.4% vs. 11.5%; adj. HR [95% CI]: 1.3 [1.0, 1.7], p=0.12), target lesion failure (12...
November 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27818380/novel-minimally-invasive-surgical-approach-using-an-external-ventricular-assist-device-and-extracorporeal-membrane-oxygenation-in-refractory-cardiogenic-shock
#2
Koji Takeda, Arthur R Garan, Veli K Topkara, Ajay J Kirtane, Dimitri Karmpaliotis, Paul Kurlansky, Melana Yuzefpolskaya, Paolo C Colombo, Yoshifumi Naka, Hiroo Takayama
OBJECTIVES: The use of short-term mechanical circulatory support (MCS) has increased in the treatment of refractory cardiogenic shock (RCS). Percutaneous short-term MCS technology has emerged rapidly; however, limitations in flow and durability remain. We therefore investigated a minimally invasive surgical approach using an external ventricular assist device (VAD) and extracorporeal membrane oxygenation (ECMO) in patients with RCS. METHODS: Twenty-five patients underwent minimally invasive external VAD insertion with a magnetically levitated centrifugal pump for various causes of cardiogenic shock between April 2010 and May 2016...
November 6, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27814787/relation-between-renal-function-and-coronary-plaque-morphology-from-the-assessment-of-dual-antiplatelet-therapy-with-drug-eluting-stents-virtual-histology-intravascular-ultrasound-substudy
#3
Chee Yang Chin, Gary S Mintz, Shigeo Saito, Bernhard Witzenbichler, D Christopher Metzger, Michael J Rinaldi, Ernest L Mazzaferri, Peter L Duffy, Giora Weisz, Thomas D Stuckey, Bruce R Brodie, Claire Litherland, Ajay J Kirtane, Gregg W Stone, Akiko Maehara
We sought to examine the relation between various degrees of renal function and coronary plaque morphology by grayscale and virtual histology intravascular ultrasound (IVUS). ADAPT-DES was a prospective, multicenter registry of 8,582 consecutive patients treated using coronary drug-eluting stents with a prespecified grayscale and virtual histology-IVUS substudy. A lesion-level analysis of study participants was performed by comparing IVUS parameters of culprit and nonculprit lesions across tertiles of estimated creatinine clearance (CrCl)...
October 7, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27765301/implications-of-public-reporting-of-risk-adjusted-mortality-following-percutaneous-coronary-intervention-misperceptions-and-potential-consequences-for-high-risk-patients-including-nonsurgical-patients
#4
Anuj Gupta, Robert W Yeh, Jacqueline E Tamis-Holland, Shalin H Patel, Robert A Guyton, Lloyd W Klein, Tanveer Rab, Ajay J Kirtane
Assessment of clinical outcomes such as 30-day mortality following coronary revascularization procedures has historically been used to spur quality improvement programs. Public reporting of risk-adjusted outcomes is already mandated in several states, and proposals to further expand public reporting have been put forward as a means of increasing transparency and potentially incentivizing high quality care. However, for public reporting of outcomes to be considered a useful surrogate of procedural quality of care, several prerequisites must be met...
October 24, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27729332/development-and-validation-of-a-scoring-system-for-predicting-periprocedural-complications-during-percutaneous-coronary-interventions-of-chronic-total-occlusions-the-prospective-global-registry-for-the-study-of-chronic-total-occlusion-intervention-progress
#5
Barbara Anna Danek, Aris Karatasakis, Dimitri Karmpaliotis, Khaldoon Alaswad, Robert W Yeh, Farouc A Jaffer, Mitul P Patel, Ehtisham Mahmud, William L Lombardi, Michael R Wyman, J Aaron Grantham, Anthony Doing, David E Kandzari, Nicholas J Lembo, Santiago Garcia, Catalin Toma, Jeffrey W Moses, Ajay J Kirtane, Manish A Parikh, Ziad A Ali, Judit Karacsonyi, Bavana V Rangan, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: High success rates are achievable for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using the hybrid approach, but periprocedural complications remain of concern. Although scores estimating success and efficiency in CTO PCI have been developed, there is currently no available score for estimation of the risk for periprocedural complications. We sought to develop a scoring tool for prediction of periprocedural complications during CTO PCI. METHODS AND RESULTS: We analyzed data from 1569 CTO PCIs in the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS CTO) using a derivation and validation sampling ratio of 2:1...
October 11, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27705889/impact-of-proximal-cap-ambiguity-on-outcomes-of-chronic-total-occlusion-percutaneous-coronary-intervention-insights-from-a-multicenter-us-registry
#6
Aris Karatasakis, Barbara A Danek, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul P Patel, John N Bahadorani, R Michael Wyman, William L Lombardi, J Aaron Grantham, David E Kandzari, Nicholas J Lembo, Anthony H Doing, Jeffrey W Moses, Ajay J Kirtane, Santiago Garcia, Manish A Parikh, Ziad A Ali, Judit Karacsonyi, Sanjog Kalra, Bavana V Rangan, Pratik Kalsaria, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
OBJECTIVES: We sought to determine the impact of proximal cap ambiguity on procedural techniques and outcomes for coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS: We examined the clinical and angiographic characteristics and outcomes of 1021 CTO-PCIs performed between 2012 and 2015 at 11 United States centers. RESULTS: Proximal cap ambiguity was present in 31% of target lesions and was associated with increased clinical and angiographic complexity (prior coronary artery bypass graft surgery: 43% vs 33%; P=...
October 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27679596/utility-of-near-infrared-spectroscopy-for-detection-of-thin-cap-neoatherosclerosis
#7
Tomasz Roleder, Keyvan Karimi Galougahi, Chee Yang Chin, Navdeep K Bhatti, Emmanouil Brilakis, Tamim M Nazif, Ajay J Kirtane, Dimitri Karmpaliotis, Wojciech Wojakowski, Martin B Leon, Gary S Mintz, Akiko Maehara, Gregg W Stone, Ziad A Ali
AIMS: Near-infrared spectroscopy (NIRS) has been employed to assess the composition of the atherosclerotic plaques in native coronary arteries. However, little is known about the detection of neoatherosclerosis by NIRS in in-stent restenosis (ISR). The aim of the study was to assess the relationship between the distribution of lipid determined by NIRS and morphology of ISR on optical coherence tomography (OCT). METHODS AND RESULTS: We performed both NIRS and OCT in 39 drug-eluting stents with ISR...
September 27, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27611917/comparison-of-various-scores-for-predicting-success-of-chronic-total-occlusion-percutaneous-coronary-intervention
#8
Aris Karatasakis, Barbara A Danek, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, John N Bahadorani, William L Lombardi, R Michael Wyman, J Aaron Grantham, David E Kandzari, Nicholas J Lembo, Anthony H Doing, Catalin Toma, Jeffrey W Moses, Ajay J Kirtane, Manish A Parikh, Ziad A Ali, Santiago Garcia, Pratik Kalsaria, Judit Karacsonyi, Aya J Alame, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: Various scoring systems have been developed to predict the technical outcome and procedural efficiency of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS: We examined the predictive capacity of 3 CTO PCI scores (Clinical and Lesion-related [CL], Multicenter CTO registry in Japan [J-CTO] and Prospective Global Registry for the Study of Chronic Total Occlusion Intervention [PROGRESS CTO] scores) in 664 CTO PCIs performed between 2012 and 2016 at 13 US centers...
August 23, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27592092/impact-of-preoperative-chronic-kidney-disease-in-2-531-high-risk-and-inoperable-patients-undergoing-transcatheter-aortic-valve-replacement-in-the-partner-trial
#9
Vinod H Thourani, Jessica Forcillo, Nirat Beohar, Darshan Doshi, Rupa Parvataneni, Girma M Ayele, Ajay J Kirtane, Vasilis Babaliaros, Susheel Kodali, Chandan Devireddy, Wilson Szeto, Howard C Herrmann, Raj Makkar, Gorav Ailawadi, Scott Lim, Hersh S Maniar, Alan Zajarias, Rakesh Suri, E Murat Tuzcu, Samir Kapadia, Lars Svensson, Jose Condado, Hanna A Jensen, Michael J Mack, Martin B Leon
BACKGROUND: Although preoperative renal dysfunction (RD) is associated with increased mortality and morbidity after surgical aortic valve replacement, its impact on clinical outcomes after transcatheter aortic valve replacement (TAVR) is less defined. METHODS: TAVR patients in the PARTNER (Placement of Aortic Transcatheter Valves) trial with a calculable glomerular filtration rate (GFR) using the Modification of Diet in Renal Disease equation were included. Patients were divided into three groups: GFR >60 mL/min (none/mild RD), GFR 31 to 60 mL/min (moderate RD), and GFR ≤30 mL/min (severe RD)...
October 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27591688/intravenous-adenosine-based-fractional-flow-reserve-in-pre-tavr-assessment-of-severe-as-finally-some-clarity
#10
EDITORIAL
Vivian G Ng, Ajay J Kirtane
No abstract text is available yet for this article.
September 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27591687/heparin-versus-bivalirudin-in-st-segment-elevation-myocardial-infarction-a-scai-based-national-survey-from-us-interventional-cardiologists
#11
Harsh Golwala, Sadip Pant, Ambarish Pandey, Michael P Flaherty, Glenn A Hirsch, Ajay J Kirtane
BACKGROUND: The use of antithrombotic therapy (ATT) (bivalirudin or unfractionated heparin) is a class I recommendation for patients undergoing primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI). This survey was conducted to better understand current United States (US) practices in terms of preferences regarding the selection of ATT in STEMI-PPCI, particularly in light of recent clinical trials. METHODS: An electronic survey consisting of 9 focused questions was forwarded to 2676 US interventional cardiologists who were members of the Society for Cardiovascular Angiography and Interventions (SCAI)...
September 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27553094/effect-of-smoking-on-infarct-size-and-major-adverse-cardiac-events-in-patients-with-large-anterior-st-elevation-myocardial-infarction-from-the-infuse-ami-trial
#12
Giustino Gennaro, Sorin J Brener, Björn Redfors, Ajay J Kirtane, Philippe Généreux, Akiko Maehara, Thomas Neunteufl, D Christopher Metzger, Roxana Mehran, C Michael Gibson, Gregg W Stone
We sought to investigate the effect of smoking on infarct size (IS) and major adverse cardiac events (MACE) in patients with large anterior ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Participants from the Intracoronary Abciximab and Aspiration Thrombectomy in Patients with Large Anterior Myocardial Infarction study were categorized according to smoking status (current or previous smoking vs no history of smoking). The primary imaging outcome was cardiac magnetic resonance imaging-assessed IS of left ventricular mass (%) at 30 days...
October 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27543999/case-11-2016-perioperative-coronary-thrombosis-in-a-patient-with-multiple-second-generation-drug-eluting-stents-is-it-time-for-a-paradigm-shift
#13
Michael K Essandoh, Adam A Dalia, Barry S George, Antolin S Flores, Andrew J Otey, Ajay J Kirtane, Thomas M Broderick, Sunil V Rao
No abstract text is available yet for this article.
December 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27543800/use-of-intravascular-imaging-during-chronic-total-occlusion-percutaneous-coronary-intervention-insights-from-a-contemporary-multicenter-registry
#14
Judit Karacsonyi, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, John Bahadorani, Aris Karatasakis, Barbara A Danek, Anthony Doing, J Aaron Grantham, Dimitri Karmpaliotis, Jeffrey W Moses, Ajay Kirtane, Manish Parikh, Ziad Ali, William L Lombardi, David E Kandzari, Nicholas Lembo, Santiago Garcia, Michael R Wyman, Aya Alame, Phuong-Khanh J Nguyen-Trong, Erica Resendes, Pratik Kalsaria, Bavana V Rangan, Imre Ungi, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: Intravascular imaging can facilitate chronic total occlusion (CTO) percutaneous coronary intervention. METHODS AND RESULTS: We examined the frequency of use and outcomes of intravascular imaging among 619 CTO percutaneous coronary interventions performed between 2012 and 2015 at 7 US centers. Mean age was 65.4±10 years and 85% of the patients were men. Intravascular imaging was used in 38%: intravascular ultrasound in 36%, optical coherence tomography in 3%, and both in 1...
2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27515241/accreditation-and-funding-for-a-24-month-advanced-interventional-cardiology-fellowship-program-a-call-to-action-for-optimal-training-of-the-next-generation-of-interventionalists
#15
Ankur Kalra, Deepak L Bhatt, Duane S Pinto, Ajay J Kirtane, Samir R Kapadia, Raj R Makkar, Charanjit S Rihal, Neal S Kleiman, Donald E Cutlip
No abstract text is available yet for this article.
August 12, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27491836/diagnosis-and-management-of-cardiovascular-disease-in-advanced-and-end-stage-renal-disease
#16
REVIEW
Navdeep K Bhatti, Keyvan Karimi Galougahi, Yehuda Paz, Tamim Nazif, Jeffrey W Moses, Martin B Leon, Gregg W Stone, Ajay J Kirtane, Dimitri Karmpaliotis, Sabahat Bokhari, Mark A Hardy, Geoffrey Dube, Sumit Mohan, Lloyd E Ratner, David J Cohen, Ziad A Ali
No abstract text is available yet for this article.
2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27478119/prevalence-and-clinical-impact-of-tissue%C3%A2-protrusion-after-stent-implantation-an-adapt-des-intravascular-ultrasound-substudy
#17
Fuyu Qiu, Gary S Mintz, Bernhard Witzenbichler, D Christopher Metzger, Michael J Rinaldi, Peter L Duffy, Giora Weisz, Thomas D Stuckey, Bruce R Brodie, Rupa Parvataneni, Ajay J Kirtane, Gregg W Stone, Akiko Maehara
OBJECTIVES: The aim of this study was to evaluate the prevalence and long-term clinical impact of tissue protrusion (TP) after stent implantation. BACKGROUND: Stent implantation may be associated with tissue (plaque or thrombus) protrusion, especially in unstable lesions, but its clinical impact is unknown. METHODS: ADAPT-DES (Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents) was a prospective multicenter study of 8,663 patients undergoing percutaneous coronary intervention (PCI) using drug-eluting stents...
July 25, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27476986/effect-of-lesion-age-on-outcomes-of-chronic-total-occlusion-percutaneous-coronary-intervention-insights-from-a-contemporary-us-multicenter-registry
#18
Barbara A Danek, Aris Karatasakis, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul P Patel, John Bahadorani, William L Lombardi, R Michael Wyman, J Aaron Grantham, David E Kandzari, Nicholas J Lembo, Anthony H Doing, Catalin Toma, Jeffrey W Moses, Ajay J Kirtane, Ziad A Ali, Manish Parikh, Santiago Garcia, Phuong-Khanh Nguyen-Trong, Judit Karacsonyi, Aya J Alame, Pratik Kalsaria, Craig Thompson, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: We sought to determine the effect of lesion age on procedural techniques and outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS: We examined the characteristics and outcomes of 394 CTO PCIs with data on lesion age, performed between 2012 and 2016 at 11 experienced US centres. RESULTS: Mean patient age was 66 ± 10 years and 85.6% of the patients were men. Overall technical and procedural success rates were 90...
December 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27470451/underutilization-of-coronary-artery-disease-testing-among-patients-hospitalized-with-new-onset-heart-failure
#19
Darshan Doshi, Ori Ben-Yehuda, Machaon Bonafede, Noam Josephy, Dimitri Karmpaliotis, Manish A Parikh, Jeffrey W Moses, Gregg W Stone, Martin B Leon, Allan Schwartz, Ajay J Kirtane
BACKGROUND: Although ischemic coronary artery disease (CAD) is the most common etiology of heart failure (HF), the extent to which patients with new-onset HF actually undergo an ischemic work-up and/or revascularization is not well defined. OBJECTIVES: This study sought to analyze the patterns of testing for ischemic CAD and revascularization in patients with new-onset HF. METHODS: This was a retrospective cohort study using Truven Health MarketScan Commercial and Medicare databases from 2010 to 2013...
August 2, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27463249/the-complicated-calculus-of-publicly-reporting-mortality-after-percutaneous-coronary-intervention
#20
Ajay J Kirtane, Brahmajee K Nallamothu, Jeffrey W Moses
No abstract text is available yet for this article.
September 1, 2016: JAMA Cardiology
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