Eun-Jung Kang, Jae-Hoon Kim, Young Eun Kim, Hana Lee, Kwang Bo Jung, Dong-Ho Chang, Youngjin Lee, Shinhye Park, Eun-Young Lee, Eun-Ji Lee, Ho Bum Kang, Moon-Young Rhyoo, Seungwoo Seo, Sohee Park, Yubin Huh, Jun Go, Jung Hyeon Choi, Young-Keun Choi, In-Bok Lee, Dong-Hee Choi, Yun Jeong Seo, Jung-Ran Noh, Kyoung-Shim Kim, Jung Hwan Hwang, Ji-Seon Jeong, Ha-Jeong Kwon, Hee Min Yoo, Mi-Young Son, Yeon-Gu Kim, Dae-Hee Lee, Tae-Young Kim, Hyo-Jung Kwon, Myung Hee Kim, Byoung-Chan Kim, Yong-Hoon Kim, Dukjin Kang, Chul-Ho Lee
Akkermansia muciniphila has received great attention because of its beneficial roles in gut health by regulating gut immunity, promoting intestinal epithelial development, and improving barrier integrity. However, A. muciniphila-derived functional molecules regulating gut health are not well understood. Microbiome-secreted proteins act as key arbitrators of host-microbiome crosstalk through interactions with host cells in the gut and are important for understanding host-microbiome relationships. Herein, we report the biological function of Amuc_1409, a previously uncharacterised A...
April 6, 2024: Nature Communications