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https://www.readbyqxmd.com/read/29793176/non-ldl-dyslipidemia-is-prevalent-in-the-young-and-determined-by-lifestyle-factors-and-age-the-lifelines-cohort
#1
Jeroen K de Vries, Jan W Balder, Michelle J Pena, Petra Denig, Andries J Smit
BACKGROUND AND AIMS: Non-LDL dyslipidemia (NLD) confers cardiovascular risk, and prevalence rates appear to be high in elderly populations. Small cohorts have identified several lifestyle, anthropometric, and medical factors associated with NLD. We aimed to assess sex- and age-specific prevalence of NLD in a contemporary population cohort (n = 167 729), and to identify independent determinants of NLD, focusing on lifestyle, anthropometric, and medical factors. METHODS: The prevalence of NLD was assessed per 10-year age intervals in adults without cardiovascular disease not using lipid-modifying drugs from the Dutch LifeLines cohort...
May 21, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29792202/the-effects-of-a-lifestyle-focused-text-messaging-intervention-on-adherence-to-dietary-guideline-recommendations-in-patients-with-coronary-heart-disease-an-analysis-of-the-text-me-study
#2
Karla Santo, Karice Hyun, Laura de Keizer, Aravinda Thiagalingam, Graham S Hillis, John Chalmers, Julie Redfern, Clara K Chow
BACKGROUND: A healthy diet is an important component of secondary prevention of coronary heart disease (CHD). The TEXT ME study was a randomised clinical trial of people with CHD that were randomised into standard care or a text-message programme in addition to standard care. This analysis aimed to: 1) assess the effects of the intervention onadherence to the dietary guideline recommendations; 2) assess the consistency of effect across sub-groups; and 3) assess whether adherence to the dietary guideline recommendations mediated the improvements in objective clinical outcomes...
May 23, 2018: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29789804/health-risk-behaviour-among-adolescents-living-with-hiv-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#3
REVIEW
Derrick Ssewanyana, Patrick N Mwangala, Anneloes van Baar, Charles R Newton, Amina Abubakar
The burden of health risk behaviour (HRB) among adolescents living with HIV (ALWHIV) in sub-Saharan Africa (SSA) is currently unknown. A systematic search for publications on HRB among ALWHIV in SSA was conducted in PubMed, Embase, PsycINFO, and Applied Social Sciences Index and Abstracts databases. Results were summarized following PRISMA guidelines for systematic reviews and meta-analyses. Heterogeneity was assessed by the DerSimonian and Laird method and the pooled estimates were computed. Prevalence of current condom nonuse behaviour was at 59...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29788484/an-e-liquid-flavor-wheel-a-shared-vocabulary-based-on-systematically-reviewing-e-liquid-flavor-classifications-in-literature
#4
Erna Johanna Zegerina Krüsemann, Sanne Boesveldt, Kees de Graaf, Reinskje Talhout
Introduction: E-liquids are available in a high variety of flavors. A systematic classification of e-liquid flavors is necessary to increase comparability of research results. In the food, alcohol and fragrance industry, flavors are classified using flavor wheels. We systematically reviewed literature on flavors related to e-cigarette use, to investigate how e-liquid flavors have been classified in research, and propose an e-liquid flavor wheel to classify e-liquids based on marketing descriptions...
May 18, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29785797/relationship-between-handgrip-strength-and-pulmonary-function-in-apparently-healthy-older-women
#5
Da-Hye Son, Ji-Won Yoo, Mi-Ra Cho, Yong-Jae Lee
OBJECTIVES: To investigate the relationship between handgrip strength and pulmonary function. DESIGN: Cross-sectional study of a representative sample of older Korean women. SETTING: The Korean National Health and Nutrition Examination Survey. PARTICIPANTS: Community-dwelling women aged 65 and older without chronic diseases or pulmonary disease (N=605). MEASUREMENTS: Handgrip strength was measured using a digital hand dynamometer, and pulmonary function was tested according to guidelines of the American Thoracic Society/European Respiratory Society using a spirometry system...
May 21, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29785393/monitoring-methotrexate-induced-liver-fibrosis-in-patients-with-psoriasis-utility-of-transient-elastography
#6
REVIEW
Harriet S Cheng, Marius Rademaker
Increasingly, existing evidence indicates that methotrexate-associated liver injury is related to comorbid risk factors such as diabetes, alcoholism, and obesity, rather than to methotrexate itself. Despite this fact, significant effort continues to be expended in the monitoring of low-dose methotrexate in patients with psoriasis. The gold standard investigation has been liver biopsy, but this is associated with significant morbidity and mortality. As methotrexate-induced liver injury is uncommon, the risk/benefit ratio of liver biopsy has been questioned...
2018: Psoriasis: Targets and Therapy
https://www.readbyqxmd.com/read/29782664/stereoselective-hplc-separation-of-alvimopan-on-cellulose-based-immobilized-polysaccharide-as-a-chiral-stationary-phase
#7
Nitin H Dhekale, Dattatray B Gunjal, Anil H Gore, Yagnakirankumar Komaravolu, K Hima Bindu, Govind B Kolekar
Chiral separation by normal phase high performance liquid chromatography is one of the most powerful technique to quantify the chiral purity of the compounds. In this study, a novel, simple, and specific analytical method was proposed to ascertain the chiral purity of alvimopan (ALV). The normal phase HPLC method was developed based on cellulose tris (3,5-dichlorophenylcarbamate) stationary phase. The separation of ALV isomers achieved by using column CHIRALPAK IC (250 × 4.6 mm, 5 μm), mobile phase n-hexane: isopropyl alcohol: ethanol: diethylamine (650:200:150:5 v/v), column oven temperature 30°C, flow rate 1...
May 21, 2018: Chirality
https://www.readbyqxmd.com/read/29781162/predictors-of-ultrasound-failure-to-detect-hepatocellular-carcinoma
#8
Mariya L Samoylova, Neil Mehta, John P Roberts, Francis Y Yao
Current guidelines recommend ultrasound (US) for hepatocellular carcinoma (HCC) surveillance in cirrhosis. We assess predictors of decreased US sensitivity for detecting HCC. At a single U.S. center, all HCC patients evaluated for liver transplant (LT) receive an abdominal US. In consecutive patients presenting 2007-2015, untreated lesions found on CT/MRI within 3 months of US were compared with US findings. Multivariable logistic regression models compared US sensitivities by patient characteristics. Of 1008 patients completing LT evaluation, 47...
May 21, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/29779198/redeveloping-substance-abuse-treatment-for-military-personnel
#9
REVIEW
Christian Schrader, Antoinette Lenton, Peter Gertonson, Alexander Rahimi
PURPOSE OF REVIEW: We review the prevailing evidence surrounding treatment of substance use disorder (SUD), with specific focus on alcohol, tobacco, and prescription opiates, and how it informs guidelines for treating active duty military. We survey the evidence regarding preventive screening, treatment, and relapse prevention in substance misuse as it pertains to patient-centered care of the service member. RECENT FINDINGS: Holistic, patient-centered care with an emphasis on identifying maladaptive use or dependence prior to progression to chronic disease is now recognized as the evidenced approach to treating substance use disorders...
May 19, 2018: Current Psychiatry Reports
https://www.readbyqxmd.com/read/29778667/cardiovascular-risk-factors-is-the-metabolic-syndrome-related-to-aging-epidemiology-in-a-portuguese-population
#10
Armindo Sousa Ribeiro, Rui Seixas, Juan Manuel Gálvez, Vicente Climent
AIMS: The primary objective of our study is to determine the prevalence of the metabolic syndrome in the population. The secondary objective is to determine the prevalence of cardiovascular risk factors, anthropometric alterations and the prevalence of target organ damage and their relationship with aging. MATERIAL AND METHODS: The sample for the study was obtained by means of a consecutive population-based demonstration in 803 adults over 18 years of age belonging to the labor force of the company Grupo Delta SA...
May 16, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29766824/adipose-derived-mesenchymal-stem-cells-in-the-treatment-of-obesity-a-systematic-review-of-longitudinal-studies-on-preclinical-evidence
#11
Fatima Saleh, Leila Itani, Simona Calugi, Riccardo Dalle Grave, Marwan El Ghoch
BACKGROUND: Obesity is an increasing global health problem, but its treatment is not yet optimal, especially in the long term. For this reason, preclinical studies have been conducted relating to a new therapeutic strategy for obesity based on adipose-derived mesenchymal stem cells (AD-MSCs). The aim of our systematic review is to summarize these findings deriving from the animal model in order to establish whether there is sufficient evidence to justify going forward to clinical studies...
May 15, 2018: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29765460/the-role-of-intestinal-microbiota-in-the-pathogenesis-of-nafld-starting-points-for-intervention
#12
Umberto Vespasiani-Gentilucci, Paolo Gallo, Antonio Picardi
In recent years, close links between intestinal microbiota and host metabolism have been recognized. Intestinal bacteria can participate in the extraction of calories from food, and circulation of bacterial products, in particular lipopolysaccharides (LPS), is responsible for the "metabolic endotoxemia", which contributes to insulin resistance and its complications, such as non-alcoholic fatty liver disease (NAFLD). Indeed, qualitative and quantitative intestinal dysbiotic changes have been clearly documented in NAFLD patients, and several mechanisms by which the intestinal microbiota can directly promote liver fat deposition, inflammation and fibrosis have also been described...
April 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29758278/prevalence-of-and-risk-factors-associated-with-latent-tuberculosis-in-singapore-a-cross-sectional-survey
#13
Peiling Yap, Kristin Hui Xian Tan, Wei Yen Lim, Timothy Barkham, Linda Wei Lin Tan, Mark Chen I-Cheng, Yee Tang Wang, Cynthia Bin Eng Chee
OBJECTIVES: We performed the first LTBI cross-sectional survey in Singapore, utilizing the QuantiFERON Gold In-tube (QFT-GIT) assay to collect data on the prevalence of LTBI and identify potential risk factors associated with it. METHODS: Nation-wide household addresses were randomly selected for enumeration, where Singaporeans or Permanent Residents (PRs), aged 18-79 years, were identified. One eligible member per household was selected using the Kish grid. Each participant answered a questionnaire, assessing medical history (including TB), socio-economic factors and lifestyle and provided a blood specimen for the QFT-GIT assay...
May 11, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29754910/lifestyle-advice-and-interventions-for-cardiovascular-risk-reduction-a-systematic-review-of-guidelines
#14
Mohammed Y Khanji, Claudia N van Waardhuizen, Vinícius V S Bicalho, Bart S Ferket, M G Myriam Hunink, Steffen E Petersen
BACKGROUND: Lifestyle factors are important in preventing cardiovascular disease (CVD) development. We aimed to systematically review guidelines on primary prevention of CVD and their recommendations on lifestyle advice or intervention, in order to guide primary prevention programs. METHODS: Publications in MEDLINE, CINAHL over 7 years since May 3, 2009 were identified. G-I-N International Guideline Library, National Guidelines Clearinghouse, National Library for Health Guideline finder, Canadian Medical Association InfoBase were searched...
July 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29752804/evaluating-behavioral-health-surveillance-systems
#15
Alejandro Azofeifa, Donna F Stroup, Rob Lyerla, Thomas Largo, Barbara A Gabella, C Kay Smith, Benedict I Truman, Robert D Brewer, Nancy D Brener
In 2015, more than 27 million people in the United States reported that they currently used illicit drugs or misused prescription drugs, and more than 66 million reported binge drinking during the previous month. Data from public health surveillance systems on drug and alcohol abuse are crucial for developing and evaluating interventions to prevent and control such behavior. However, public health surveillance for behavioral health in the United States has been hindered by organizational issues and other factors...
May 10, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29750044/successful-control-of-resistance-in-pseudomonas-aeruginosa-using-antibiotic-stewardship-and-infection-control-programs-at-a-chinese-university-hospital-a-6-year-prospective-study
#16
Lei Liu, Bin Liu, Yu Li, Wei Zhang
Objective: Pseudomonas aeruginosa is emerging as a highly multidrug-resistant (MDR) nosocomial pathogen. Data on the efficacy of infection control measures in endemic situations are lacking. We investigated the effect of antimicrobial stewardship (AMS) and infection control programs (ICPs) in controlling the resistance of P. aeruginosa at a tertiary hospital center. Methods: Susceptibility and resistance were investigated using broth microdilution, as per the guidelines of the Clinical and Laboratory Standards Institute...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29747678/a-potential-link-between-polycystic-ovary-syndrome-and-non-alcoholic-fatty-liver-disease-an-update-meta-analysis
#17
Jia Wu, Xin-Yu Yao, Ru-Xia Shi, Su-Fen Liu, Xiao-Yong Wang
BACKGROUND: Epidemiological literature regarding the effect of polycystic ovary syndrome (PCOS) as a risk factor for non-alcoholic fatty liver disease (NAFLD) remains inconsistent. Furthermore, it remains debatable whether NAFLD is associated with PCOS as a consequence of shared risk factors or whether PCOS contributes to NAFLD in an independent fashion. Therefore, this meta-analysis was conducted. METHODS: This meta-analysis was conducted in accordance with the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)...
May 10, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29746635/smoking-in-correctional-settings-worldwide-prevalence-bans-and-interventions
#18
Anne C Spaulding, Gloria D Eldridge, Cynthia E Chico, Nancy Morisseau, Ana Drobeniuc, Rebecca Fils-Aime, Carolyn Day, Robyn Hopkins, Xingzhong Jin, Junyu Chen, Kate A Dolan
Smoking tobacco contributes to 11.5% of deaths worldwide and, in some countries, more hospitalizations than alcohol and drugs combined. Globally in 2015, 25% of men and 5% of women smoked. In the United States, a higher proportion of people in prison smoke than do community-dwelling individuals. To determine smoking prevalence in prisons worldwide, we systematically reviewed the literature using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines; we also examined whether prisons banned smoking or treated smokers...
May 8, 2018: Epidemiologic Reviews
https://www.readbyqxmd.com/read/29746264/adherence-to-american-cancer-society-guidelines-on-nutrition-and-physical-activity-in-female-cancer-survivors-results-from-a-randomized-controlled-trial-yale-fitness-intervention-trial
#19
So-Hyun Park, M Tish Knobf, Jane Kerstetter, Sangchoon Jeon
BACKGROUND: The American Cancer Society (ACS) publishes guidelines on nutrition and physical activity to minimize health risks in cancer patients and survivors. Studies show that high adherence to such guidelines is associated with a decrease in overall cancer incidence and mortality. However, there are sparse data on adherence to the ACS guidelines in cancer survivors. OBJECTIVE: The aim of this study was to describe adherence to the ACS guidelines in female cancer survivors who participated in an exercise intervention trial for 1 year...
May 9, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29743785/effect-of-organic-dust-exposure-on-pulmonary-functions-in-workers-of-vegetable-market-with-special-reference-to-its-microbial-content
#20
Arun Goel, Balram Ji Omar, Rajesh Kathrotia, Prashant M Patil, Sunita Mittal
Context: Wholesale vegetable market is a rich source of generation of organic dust as loads of fruits and vegetables are loaded and unloaded here daily. Thus, regular workers are exposed to this organic dust for a considerable period of time depending on their work schedule. This study was planned to determine the microbial status of organic dust and to explore its association with pulmonary functions in the workers of wholesale vegetable market in Rishikesh. Materials and Methods: It was a cross-sectional exploratory/observational study...
January 2018: Indian Journal of Occupational and Environmental Medicine
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