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Bilateral supraclavicular

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https://www.readbyqxmd.com/read/28258891/directly-improving-the-quality-of-radiation-treatment-through-peer-review-a%C3%A2-cross-sectional-analysis-of-cancer-centers-across-a-provincial-cancer-program
#1
Julie Rouette, Eric Gutierrez, Jennifer O'Donnell, Lindsay Reddeman, Margaret Hart, Sophie Foxcroft, Gunita Mitera, Padraig Warde, Michael D Brundage
PURPOSE: To describe the outcomes of peer review across all 14 cancer centers in Ontario. METHODS AND MATERIALS: We identified all peer-reviewed, curative treatment plans delivered in Ontario within a 3-month study period from 2013 to 2014 using a provincial cancer treatment database and collected additional data on the peer-review outcomes. RESULTS: Considerable variation was found in the proportion of peer-reviewed plans across the centers (average 70...
October 20, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28225994/a-rare-case-of-ectopic-acth-syndrome-originating-from-malignant-renal-paraganglioma
#2
Esra Tutal, Demet Yılmazer, Taner Demirci, Evrim Cakır, Salih Sinan Gültekin, Bahadır Celep, Oya Topaloğlu, Erman Çakal
Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of a non-pituitary ACTH-secreting tumor leading to Cushing's syndrome. Only a few cases have been reported previously as causing ectopic ACTH related to paraganglioma. Herein, we present a case of Cushing's syndrome, in who was proved to be attributable to an ACTH-secreting renal malignant paraganglioma. A 40-year-old woman presented with a five-month history of newly diagnosed hypertension and diabetes, weakness, hyperpigmentation, oligomenorrhea, hirsutism, and acneiform lesions...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28224401/synchronous-bilateral-breast-cancer-irradiation-clinical-and-dosimetrical-issues-using-volumetric-modulated-arc-therapy-and-simultaneous-integrated-boost
#3
Alba Fiorentino, Rosario Mazzola, Stefania Naccarato, Niccolò Giaj-Levra, Sergio Fersino, Gianluisa Sicignano, Umberto Tebano, Francesco Ricchetti, Ruggero Ruggieri, Filippo Alongi
OBJECTIVES: The aim of the present retrospective analysis was to evaluate dosimetric parameters, feasibility and outcome for Synchronous Bilateral Breast Cancer (SBBC) patients treated with adjuvant radiotherapy (RT) by Volumetric Modulated Arc Therapy (VMAT). METHODS: From September 2011 to April 2016, 1100 Breast Cancer (BC) patients were referred to our institution to receive adjuvant breast RT, and those with SBBC were selected for the present analysis. A total of 16 patients were identified...
February 21, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28203178/a-patient-with-supraclavicular-lymphadenopathy-and-anterior-mediastinal-mass-presenting-as-a-rare-case-of-composite-lymphoma-a-case-report-and-literature-review
#4
Alex Raufi, James Jerkins, Yung Lyou, Deepa Jeyakumar
Composite lymphoma (CL) is a rare disease with 2 distinct lymphomas concurrently arising in a single patient with an estimated incidence of 1-4.7% of newly diagnosed lymphomas per year. CL most commonly involves 2 B-cell non-Hodgkin lymphomas (NHL) or a B-cell NHL with a Hodgkin lymphoma. Our case is unique in that it was a bilineage CL with both a T-cell and B-cell NHL, which has only been reported in a few case reports. A 49-year-old woman presented with several months of progressive cough, weight loss, dyspnea, and supraclavicular lymphadenopathy...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/28180101/evaluation-of-complications-after-surgical-treatment-of-thoracic-outlet-syndrome
#5
Mohammad Ali Hosseinian, Ali Gharibi Loron, Yalda Soleimanifard
BACKGROUND: Surgical treatment of thoracic outlet syndrome (TOS) is necessary when non-surgical treatments fail. Complications of surgical procedures vary from short-term post-surgical pain to permanent disability. The outcome of TOS surgery is affected by the visibility during the operation. In this study, we have compared the complications arising during the supraclavicular and the transaxillary approaches to determine the appropriate approach for TOS surgery. METHODS: In this study, 448 patients with symptoms of TOS were assessed...
February 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28152739/toward-quality-peer-review-outcomes-of-peer-review-across-provincial-radiation-oncology-programs
#6
Jennifer O'Donnell, Sophie Foxcroft, Margaret Hart, Eric Gutierrez, Lindsay Elizabeth Reddeman, Gunita Mitera, Padraig Richard Warde, Michael Donald Brundage
205 Background: Review of treatment plans by a second radiation oncologist is an important quality indicator in radiation oncology. Peer review (PR) can improve quality of care in individual patients by detecting clinical and planning issues and recommending plan changes. This study reports the frequency and nature of these changes across all 14 radiation oncology programs (ROPs) in Ontario, Canada. METHODS: We identified all peer-reviewed curative treatment plans delivered in Ontario within a 3-month study period between Dec 2013-Nov 2014 using Cancer Care Ontario's Activity Level Reporting System, where data on treatment intent and date, disease site treated, PR status, timing of PR, and nature of recommended changes were available...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28069039/supraclavicular-lymph-node-incisional-biopsies-have-no-influence-on-the-prognosis-of-advanced-non-small-cell-lung-cancer-patients-a-retrospective-study
#7
Song Dong, Ning Zhao, Wei Deng, Hui-Wen Sun, Fei-Yu Niu, Jin-Ji Yang, Wen-Zhao Zhong, Feng Li, Hong-Hong Yan, Chong-Rui Xu, Qiu-Yi Zhang, Xue-Ning Yang, Ri-Qiang Liao, Qiang Nie, Yi-Long Wu
BACKGROUND: Supraclavicular lymph node (SCLN) biopsies play an important role in diagnosing and staging lung cancer. However, not all patients with SCLN metastasis can have a complete resection. It is still unknown whether SCLN incisional biopsies affect the prognosis of non-small cell lung cancer (NSCLC) patients. METHODS: Patients who were histologically confirmed to have NSCLC with SCLN metastasis were enrolled in the study from January 2007 to December 2012 at Guangdong Lung Cancer Institute...
January 9, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28008776/lymph-node-standardized-uptake-values-at-pretreatment-18-f-fluorodeoxyglucose-positron-emission-tomography-as-a-valuable-prognostic-factor-for-distant-metastasis-in-nasopharyngeal-carcinoma
#8
Yuri Jeong, Seunghee Baek, Jae Won Park, Ji Hyeon Joo, Jae Seung Kim, Sang-Wook Lee
OBJECTIVE: The aim of the present study was to evaluate prognostic values of pretreatment (18)F-FDG PET parameters for predicting distant metastasis (DM) of nasopharyngeal cancer. METHODS: Seventy-three patients diagnosed with nasopharyngeal cancer with regional lymph node (LN) involvement who underwent pretreatment (18)F-FDG PET evaluation between January 2005 and December 2012 were retrospectively reviewed. We assessed the (18)F-FDG PET parameters of the primary tumors (T-) and regional LNs (N-)...
December 23, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27680713/the-lesion-distribution-among-281-patients-with-sporadic-neuralgic-amyotrophy
#9
Mark A Ferrante, Asa J Wilbourn
INTRODUCTION: The muscles commonly affected by neuralgic amyotrophy (NA) are well known, but the location of the responsible lesions is less clear (plexus versus extraplexus). METHODS: We report the lesion locations in 281 NA patients as determined by extensive electrodiagnostic (EDX) testing. RESULTS: Our 281 patients had 322 bouts of NA, 57 of which were bilateral, for a total of 379 assessable events. A single nerve was involved in 174 (46%), and 205 (54%) were multifocal...
September 28, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27527674/reconstruction-of-cica-contracture-on-the-face-and-neck-with-skin-flap-and-expanded-skin-flap-pedicled-by-anterior-branch-of-transverse-cervical-artery
#10
Baoguo Chen, Huifeng Song, Minghuo Xu, Quanwen Gao
PURPOSE: A high-quality flap is necessary for repairing faciocervical scar contractures. The supraclavicular region and chest wall are the preferred choices for reconstruction. The supraclavicular island flap (SIF) pedicled by the transverse cervical artery (TCA) has been reported. Compared to the traditional SIF flap, another type of flap pedicled by the anterior perforator of transverse cervical artery (ap-TCA) is more convenient for transfer to the faciocervical area. In this article, we use this type of perforator flap and expanded perforator flap to repair the faciocervical contracture...
September 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27525184/screening-for-referral-by-a-sports-physical-therapist-reveals-an-effort-thrombosis-in-a-collegiate-pitcher-a-case-report
#11
William R VanWye, Jase Pinerola, Karen Craig Ogle, Harvey W Wallmann
BACKGROUND AND PURPOSE: Screening for referral, regardless of setting, is the responsibility of all physical therapists. A serious condition that sports physical therapists may encounter is upper extremity (UE) deep venous thrombosis (DVT), which can result in the important and sometimes fatal complication of pulmonary embolism. CASE DESCRIPTION: A 22 year-old male right-hand dominant collegiate pitcher was referred for physical therapist evaluation and treatment secondary to acute right UE pain and swelling...
August 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27471393/postoperative-radiation-in-esophageal-squamous-cell-carcinoma-and-target-volume-delineation
#12
REVIEW
Yingming Zhu, Minghuan Li, Li Kong, Jinming Yu
Esophageal cancer is the sixth leading cause of cancer death worldwide, and patients who are treated with surgery alone, without neoadjuvant therapies, experience frequent relapses. Whether postoperative therapies could reduce the recurrence or improve overall survival is still controversial for these patients. The purpose of our review is to figure out the value of postoperative adjuvant therapy and address the disputes about target volume delineation according to published data. Based on the evidence of increased morbidity and disadvantages on patient survival caused by postoperative chemotherapy or radiotherapy (RT) alone provided by studies in the early 1990s, the use of postoperative adjuvant therapies in cases of esophageal squamous cell carcinoma has diminished substantially and has been replaced gradually by neoadjuvant chemoradiation...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27461534/unusual-gastric-mucosal-infiltration-by-a-medullary-thyroid-carcinoma-a-case-report
#13
T Karrasch, W Doppl, F C Roller, A Schäffler, R Schäffer, S Gattenlöhner
BACKGROUND: Medullary thyroid carcinoma accounts for approximately 1 to 2 % of all thyroid carcinoma cases. The most common route of dissemination is to locoregional lymph nodes. Distant metastases commonly affect bones, lungs, and liver. We present a case of a white woman with a 25-year history of medullary thyroid carcinoma on multiple medications including tyrosine kinase inhibitor therapy for the last 11 months, who exhibited unusual diffuse infiltration of advanced stage medullary thyroid carcinoma to her gastric mucosa...
July 27, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27381065/carcinoma-of-gall-bladder-with-distant-metastasis-to-breast-parenchyma-report-of-a-case-and-review-of-literature
#14
Damodara Kumaran, Manikandan Anamalai, Umesh Velu, Aruna Nambirajan, Pramod Kumar Julka
BACKGROUND: Gall bladder carcinoma is one of the most common cancers in India. Gall bladder cancer with metastasis to the breast is very rare. Herein we intend to report a case of carcinoma gall bladder with breast metastasis and a short review of the literature. METHODS: This report describes an interesting and unusual case of gall bladder carcinoma presenting with breast metastasis. CASE REPORT: A 38-year lady presented with complaints of right abdominal pain...
December 2016: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/27353521/the-surgical-anatomy-of-the-supraclavicular-lymph-node-flap-a-basis-for-the-free-vascularized-lymph-node-transfer
#15
Johannes Steinbacher, Ines E Tinhofer, Stefan Meng, Lukas F Reissig, Eva Placheta, Julia Roka-Palkovits, Thomas Rath, Ming-Huei Cheng, Wolfgang J Weninger, Chieh Han Tzou
BACKGROUND: Vascularized lymph node transfer is an effective surgical method in reducing lymphedema. This study provides the first detailed description of the surgical anatomy of the supraclavicular lymph node flap in regard to pedicle length, pedicle diameter, and the number of lymph nodes and their exact location inside the flap. METHODS: Bilateral supraclavicular dissections of nine fresh cadavers (five female) were performed. Before the dissection, the exact number of lymph nodes was determined sonographically by an experienced radiologist, and their distance from the jugular notch was measured...
January 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27284253/image-guided-intensity-modulated-radiotherapy-for-refractory-bilateral-breast-cancer-in-a-patient-with-extensive-cutaneous-metastasis-in-the-chest-and-abdominal-walls
#16
Yueh-Feng Lu, Yu-Chin Lin, Kuo-Hsin Chen, Pei-Wei Shueng, Hsin-Pei Yeh, Chen-Hsi Hsieh
Treatment for bilateral breast cancer with chest wall and abdominal skin invasion normally involves conventional radiotherapy (RT); however, conventional RT provides inadequate target volume coverage and excessive treatment of large volumes of normal tissue. Helical tomotherapy (HT) has the ability to deliver continuous craniocaudal irradiation that suppresses junction problems and provides good conformity of dose distribution. A 47-year-old female with stage IV bilateral breast cancer with chest wall and pectoralis major muscle invasion, lymphadenopathy, bilateral pleural effusion, and multiple bone metastases received chemotherapy and target therapy beginning in January 2014; 4 months after the initiation of chemotherapy, computed tomography revealed progression of chest and abdominal wall invasion...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27272674/changes-in-brain-resting-state-functional-connectivity-associated-with-peripheral-nerve-block-a-pilot-study
#17
M Stephen Melton, Jeffrey N Browndyke, Todd B Harshbarger, David J Madden, Karen C Nielsen, Stephen M Klein
BACKGROUND: Limited information exists on the effects of temporary functional deafferentation (TFD) on brain activity after peripheral nerve block (PNB) in healthy humans. Increasingly, resting-state functional connectivity (RSFC) is being used to study brain activity and organization. The purpose of this study was to test the hypothesis that TFD through PNB will influence changes in RSFC plasticity in central sensorimotor functional brain networks in healthy human participants. METHODS: The authors achieved TFD using a supraclavicular PNB model with 10 healthy human participants undergoing functional connectivity magnetic resonance imaging before PNB, during active PNB, and during PNB recovery...
August 2016: Anesthesiology
https://www.readbyqxmd.com/read/27167311/silicone-granuloma-from-ruptured-breast-implants-as-a-cause-of-cervical-lymphadenopathy
#18
K Borghol, G Gallagher, B L Skelly
A 56-year-old woman with a 10-year history of bilateral silicone breast implants presented to the ear, nose and throat outpatient clinic with a 2-month history of a right-sided neck lump. She was found to have a 1.3cm supraclavicular lymph node that gave the clinical impression of being reactive. Ultrasonography guided fine needle aspiration was inconclusive and initial review of subsequent computed tomography failed to identify a cause. This was followed by excisional biopsy of the lymph node, which revealed a silicone granuloma that was linked to a ruptured right-sided breast implant placed ten years previously...
September 2016: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/26945389/a-case-report-systemic-lymph-node-tuberculosis-mimicking-lymphoma-on-18f-fdg-pet-ct
#19
Qingxuan Wang, Endong Chen, Yefeng Cai, Xiangjian Zhang, Quan Li, Xiaohua Zhang
F-fluorodeoxyglucose positron emission tomography--an established modality for evaluating malignancies--exhibits increased uptake under inflammatory conditions. A 21-year-old man came to our hospital with persistent pain in his right lower quadrant of abdomen for more than 1 month, but had no diarrhea, fever, chills, weight loss, or other constitutional symptoms. Colonoscopy analysis showed no organic diseases in his colorectum. Ultrasound results revealed multiple enlarged lymph nodes in the bilateral neck, axilla, and groin...
March 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26914556/psma-expression-in-papillary-thyroid-carcinoma-opening-a-new-horizon-in-management-of-thyroid-cancer
#20
Sameer Kamalakar Taywade, Nishikant Avinash Damle, Chandrasekhar Bal
Prostate-specific membrane antigen (PSMA) is a type 2 transmembrane protein highly expressed in prostate cancer cells. We present the case of a 50-year-old man with metastatic papillary carcinoma of the thyroid, with rising thyroglobulin level and negative whole-body radioiodine scan after total thyroidectomy. Considering the limited treatment options available, it was decided to perform Ga-PSMA-HBED-CC PET/CT scan. It revealed intense radiotracer uptake in mediastinal and left supraclavicular lymph nodes, brain metastases, bilateral lung nodules, and skeletal sites...
May 2016: Clinical Nuclear Medicine
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