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Bilateral supraclavicular

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https://www.readbyqxmd.com/read/29801668/a-vmat-planning-technique-for-locally-advanced-breast-cancer-patients-with-expander-or-implant-reconstructions-requiring-comprehensive-postmastectomy-radiation-therapy
#1
LiCheng Kuo, Åse M Ballangrud, Alice Y Ho, James G Mechalakos, Guang Li, Linda Hong
Locally advanced breast cancer patients with expander or implant reconstructions who require comprehensive postmastectomy radiotherapy (PMRT) can pose unique treatment planning challenges. Traditional 3D conformal radiation techniques often result in large dose inhomogeneity throughout the treatment volumes, inadequate target coverage, or excessive normal tissue doses. We have developed a volumetric modulated arc therapy (VMAT) planning technique without entering through the ipsilateral arm that produced adequate target volume coverage, excellent homogeneity throughout the target volume, and acceptable doses to the normal structures...
May 22, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29719489/renal-manifestation-of-birt-hogg-dub%C3%A3-syndrome-depicted-by-18f-fludeoxyglucose-positron-emission-tomography-computed-tomography-in-a-patient-with-hurtle-cell-thyroid-malignancy
#2
Emmanouil Panagiotidis, Nagabhushan Seshadri, Sobhan Vinjamuri
Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant genetic disorder characterized by small papular skin lesions (fibrofolliculomas) causing susceptibility to kidney cancer, renal and pulmonary cysts, spontaneous pneumothoraces, and several noncutaneous tumors. We report a case of a 67-year-old woman, with a previous history of right hemithyroidectomy for adenomatous lesion. She presented with a swelling in the right thyroid bed that on subsequent biopsy revealed features of metastatic carcinoma. 18F-fludeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) performed for the detection of primary malignancy showed increased high-grade metabolic activity in the right supraclavicular soft tissue mass extending into the superior mediastinum...
April 2018: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29707398/severe-bilateral-breast-mucinous-carcinoma-with-bilateral-lungs-and-cutaneous-metastasis-a-case-report-and-literature-review
#3
Rong Pu, Yanchu Li, Xianyong Li
The case of a female who had severe, rare, terminal breast mucinous carcinoma (BMC) and failed to receive surgery and chemotherapy was reported. The patient was diagnosed with pure BMC (ER++, PR++, CerbB-2-, and Ki-67 10%) accompanied with bilateral lungs, bilateral chest walls with skin ulcer ( D  = 14 cm), lymph nodes of bilateral armpits, and right supraclavicular metastases. ECOG (Eastern Cooperative Oncology Group) and NRS (Numeric Rating Scale) pain scores were 4 and 6, respectively. Because the patient refused traditional chemotherapy and radiotherapy on religious grounds, an herbal medicine containing Panax ginseng , Agrimonia pilosa , and white flower Patrinia herb was administered; extensive nursing for tumor debridement was also provided...
2018: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/29696329/first-rib-resection-for-thoracic-outlet-syndrome-the-robotic-approach
#4
Gregor J Kocher, Adrian Zehnder, Jon A Lutz, Juerg Schmidli, Ralph A Schmid
OBJECTIVE: First rib resection is a well-recognized treatment option for thoracic outlet syndrome (TOS). In case of a vascular insufficiency that can be provoked and/or progressive neurologic symptoms without response to conservative treatment, surgical decompression of the space between the clavicle and the first rib is indicated. The aim of this paper is to present our experience with a new minimally invasive robotic approach using the da Vinci Surgical System®. METHODS: Between January 2015 and October 2017, eight consecutive first rib resections in seven patients were performed at our institution...
April 25, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29594207/patterns-of-loco-regional-failure-in-women-with-breast-cancer-treated-by-postmastectomy-conformal-electron-beam-radiation-therapy-pmert-large-scale-single-center-experience
#5
Gokoulakrichenane Loganadane, Zhen Xi, Hao Ping Xu, Noemie Grellier Adedjouma, Louis Bazire, Alain Fourquet, Youlia M Kirova
Purpose: To evaluate loco regional control and describe the patterns of loco regional failure in women with breast cancer irradiated by a previously described post-mastectomy highly conformal electron beam radiotherapy technique. Materials and methods: We included all women irradiated by PMERT for non-metastatic breast cancer (BC) between 2007 and 2011 in our department. All cases of bilateral BC were excluded. All patients who experienced loco regional recurrence have been studied...
June 2017: Clinical and Translational Radiation Oncology
https://www.readbyqxmd.com/read/29583067/neurofibromatous-neuropathy-an-ultrastructural-study
#6
Chiara Terracciano, Christa Pachatz, Emanuele Rastelli, Francesco Saverio Pastore, Mariarosa Anna Beatrice Melone, Roberto Massa
Plexiform neurofibroma is pathognomonic of neurofibromatosis 1 (NF1). An NF1-associated peripheral neuropathy has been described in a small minority of NF1 patients but its histopathological features are poorly characterized. We report the case of a 46-year-old woman presenting with bilateral supraclavicular painful masses without other stigmata of NF1. MRI showed bilateral plexiform lesions extending from cervical roots to the elbows. Nerve conduction studies documented a sensory motor polyneuropathy. Morphometric analysis of sural nerve biopsy showed a preferential loss of large-caliber myelinated fibers with a g ratio of 0...
May 2018: Ultrastructural Pathology
https://www.readbyqxmd.com/read/29454311/radiotherapy-related-skin-toxicity-rarest-01-mepitel%C3%A2-film-versus-standard-care-in-patients-with-locally-advanced-head-and-neck-cancer
#7
Carlos Narvaez, Claudia Doemer, Christian Idel, Cornelia Setter, Denise Olbrich, Zaza Ujmajuridze, Jesper Hansen Carl, Dirk Rades
BACKGROUND: The aim of the present trial is to investigate a new option of skin protection in order to reduce the rate of grade ≥ 2 skin toxicity in patients receiving radiotherapy alone or radiochemotherapy for locally advanced squamous cell carcinoma of the head-and-neck (SCCHN). METHODS / DESIGN: This is a randomized, active-controlled, parallel-group multi-center trial that compares the following treatments of radiation dermatitis in patients with head-and-neck cancer: Mepitel® Film (Arm A) vs...
February 17, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29245295/lymphangiomatosis-involving-the-pulmonary-and-extrapulmonary-lymph-nodes-and-surrounding-soft-tissue-a-rare-case-report
#8
Xuhua Fang, Ziling Huang, Yu Zeng, Xuyou Zhu, Siqi Wang, Xiaoting Yu, Xian Li, Chunyan Wu, Xianghua Yi
BACKGROUND: Diffuse pulmonary lymphangiomatosis (DPL) mainly affects the lung and pleura. There are very few pathological reports of lung damage accompanied by diffuse involvement of the extrapulmonary lymph nodes and surrounding soft tissue. The clinicopathological significance of coexistence of pulmonary and extrapulmonary lesions is unknown. METHODS: Here, we report a 16-year-old male patient. The pathological specimens of the supraclavicular lymph node and soft tissue together with the lung biopsy were analyzed by pathological observation and immunohistochemical staining...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145318/an-unusual-cause-of-fever-of-unknown-origin-with-enlarged-lymph-nodes-relapsing-polychondritis-a-case-report
#9
Wei Liu, Hongli Jiang, Han Jing, Bing Mao
INTRODUCTION: Fever of unknown origin (FUO) is a common initial presentation leading to a diagnostic challenge. PATIENT CONCERNS: A 3-month history of moderate-to-high fever was reported in an otherwise healthy 54-year-old man. Enhanced computed tomography (CT) scans of his chest showed a remarkable progressive enlargement of bilateral cervical, supraclavicular, hilar, and mediastinal lymph nodes within 2 weeks. Bronchofibroscopy manifested obvious luminal stenosis with swelling, thick pale mucosa, and disappearing of structures of trachea cricoid cartilage, followed by a 18F-fluorodeoxyglucose positron-emission tomography-computed tomography (18F-FDG PET/CT) with intense symmetric FDG uptake in larynx, tracheobronchial tree, and hilar, mediastinal, and axillary lymph nodes being demonstrated...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28975027/second-lung-malignancy-and-richter-syndrome-in-chronic-lymphocytic-leukemia-case-report-and-literature-review
#10
Ghassen Soussi, Selsabil Daboussi, Samira Mhamdi, Zied Moatemri, Hela Ghedira, Chiraz Aichaouia, Mohsen Khadhraoui, Faouzi El Mezni, Rezaik Cheikh
BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most frequent lymphoproliferative disease. Transformation into Richter disease and occurrence of second malignancies involving the lungs are rare complications. The hallmarks of any thoracic involvement are still unknown. CASE PRESENTATION: We report a case of a 56-year-old male patient, with history of tobacco smoking, who presented with recurrent hemoptysis, fatigue and weight loss. Physical examination was normal except a slightly enlarged supraclavicular lymph node...
2017: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/28953638/anti-interferon-%C3%AE-autoantibody-associated-disseminated-mycobacterium-abscessus-infection-mimicking-parotid-cancer-with-multiple-metastases-a-case-report
#11
Po-Hsiung Chang, Yu-Chung Chuang
RATIONALE: Among the nontuberculous mycobacteria, Mycobacterium abscessus is a common cause of skin, soft tissue, and bone infections. However, disseminated M. abscessus infection that mimics cancer metastasis with an underlying relatively immunocompetent condition has rarely been reported. PATIENT CONCERNS: A nonsmoking 73-year-old man with an underlying relatively immunocompetent condition reported a 2-month history of a mass in the region of his right parotid gland that had been steadily increasing in size...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28941320/characteristics-of-the-local-recurrence-pattern-after-curative-resection-and-values-in-target-region-delineation-in-postoperative-radiotherapy-for-lower-thoracic-esophageal-squamous-cell-cancer
#12
Jun Liu, Xuwei Cai, Qi Liu, Hongxuan Li, Yan Cheng, Xiaolong Fu
BACKGROUND: The aim of this study was to investigate the patterns and influencing factors of local-regional recurrence of lower thoracic esophageal squamous cell carcinoma (TESCC) after curative resection and to delineate the clinical target volume (CTV) of postoperative radiotherapy (PORT). METHODS: From January 2009 to December 2013, the clinical data of patients who experienced local-regional recurrence after curative esophagectomy were collected and analyzed to determine local-regional recurrence patterns and to evaluate whether a proposed T-shaped PORT CTV could cover regions of local-regional failure...
November 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28796109/resurfacing-of-the-mid-and-lower-faces-by-preexpanded-supraclavicular-flap
#13
Muxin Zhao, Yangqun Li, Lisi Xu, Zhe Yang, Chunmei Hu, Yong Tang, Wen Chen, Ning Ma, Weixin Wang, Jun Feng
Extensive scarring and giant nevi on the mid and lower faces places further demands on scar resurfacing in terms of match, size, and thickness. The area of supraclavicular cervical flap is rather limited, but the expansion could expand its utility in facial resurfacing.Rectangular expanders were inserted via the incisions at the upper fringes of clavicles, and implanted under supraclavicular flap areas. After full expansion, the flap based on supraclavicular artery was elevated to cover the defects left by surgical removal of scar or tumor...
September 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28730256/advanced-metastatic-breast-cancer-in-pregnancy-the-imperative-of-physical-breast-examination-in-pregnancy
#14
Anca Angela Simionescu, Claudia Valentina Georgescu, Mirela Corina Ghiluşi, Sabrina Ioana Stoica, Mircea Dragoş Median
Breast cancer is the most frequent cancer diagnosed among women; its association with pregnancy is not encountered. As childbearing age is increasing, the diagnosis of breast cancer associated pregnancy tends to be more often than years ago. Here we report a case of a 37-year-old patient, gravida 7, para 7, diagnosed at 30 weeks gestation with metastatic breast cancer. The patient presented to hospital due to an altered performance status. Obstetrical evaluation was within normal range. A metastatic infiltrating breast cancer poorly differentiated (G3) with satellite skin lesions (T4b), ipsilateral axillary and supraclavicular lymph nodes (N3), lung metastasis bilateral with pleural effusion and hepatic metastasis (M1), were diagnosed...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28689245/imaging-of-renal-medullary-carcinoma-in-children-and-young-adults-a-report-from-the-children-s-oncology-group
#15
Jesse K Sandberg, Elizabeth A Mullen, Mariana M Cajaiba, Ethan A Smith, Sabah Servaes, Elizabeth J Perlman, James I Geller, Peter F Ehrlich, Nicholas G Cost, Jeffrey S Dome, Conrad V Fernandez, Geetika Khanna
BACKGROUND: Renal medullary carcinoma is a rare renal malignancy of childhood. There are no large series describing the imaging appearance of renal medullary carcinoma in children. OBJECTIVE: To characterize the clinical and imaging features of pediatric renal medullary carcinoma at initial presentation. MATERIALS AND METHODS: We retrospectively analyzed images of 25 pediatric patients with renal medullary carcinoma enrolled in the Children's Oncology Group renal tumors classification, biology and banking study (AREN03B2) from March 2006 to August 2016...
November 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28643685/-disseminated-interdigitating-dendritic-cell-sarcoma
#16
Ignacio M Santarelli, Mariano Veltri, Diego J Manzella, María Alejandra Avagnina, Pablo M Pereyra, Hernán C Chavín
A 70 year-old woman was admitted to our hospital with a 3-month history of abdominal pain, weight loss and night sweats. On physical examination, she presented with a 5 cm diameter abdominal mass extended from epigastrium to the left flank, and at least three bilateral supraclavicular adenopathies. A disseminated interdigitating dendritic cell sarcoma was diagnosed through a biopsy of the abdominal mass. After that, a CHOP regime (cyclophosphamide, doxorubicin, vincristine and prednisone) was iniciated. She died after completion of the first cycle of treatment, six months after diagnosis...
2017: Medicina
https://www.readbyqxmd.com/read/28258891/directly-improving-the-quality-of-radiation-treatment-through-peer-review-a-cross-sectional-analysis-of-cancer-centers-across-a-provincial-cancer-program
#17
MULTICENTER STUDY
Julie Rouette, Eric Gutierrez, Jennifer O'Donnell, Lindsay Reddeman, Margaret Hart, Sophie Foxcroft, Gunita Mitera, Padraig Warde, Michael D Brundage
PURPOSE: To describe the outcomes of peer review across all 14 cancer centers in Ontario. METHODS AND MATERIALS: We identified all peer-reviewed, curative treatment plans delivered in Ontario within a 3-month study period from 2013 to 2014 using a provincial cancer treatment database and collected additional data on the peer-review outcomes. RESULTS: Considerable variation was found in the proportion of peer-reviewed plans across the centers (average 70...
July 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28225994/a-rare-case-of-ectopic-acth-syndrome-originating-from-malignant-renal-paraganglioma
#18
Esra Tutal, Demet Yılmazer, Taner Demirci, Evrim Cakır, Salih Sinan Gültekin, Bahadır Celep, Oya Topaloğlu, Erman Çakal
Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of a non-pituitary ACTH-secreting tumor leading to Cushing's syndrome. Only a few cases have been reported previously as causing ectopic ACTH related to paraganglioma. Herein, we present a case of Cushing's syndrome, in who was proved to be attributable to an ACTH-secreting renal malignant paraganglioma. A 40-year-old woman presented with a five-month history of newly diagnosed hypertension and diabetes, weakness, hyperpigmentation, oligomenorrhea, hirsutism, and acneiform lesions...
May 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28224401/synchronous-bilateral-breast-cancer-irradiation-clinical-and-dosimetrical-issues-using-volumetric-modulated-arc-therapy-and-simultaneous-integrated-boost
#19
Alba Fiorentino, Rosario Mazzola, Stefania Naccarato, Niccolò Giaj-Levra, Sergio Fersino, Gianluisa Sicignano, Umberto Tebano, Francesco Ricchetti, Ruggero Ruggieri, Filippo Alongi
OBJECTIVES: The aim of the present retrospective analysis was to evaluate dosimetric parameters, feasibility and outcome for Synchronous Bilateral Breast Cancer (SBBC) patients treated with adjuvant radiotherapy (RT) by Volumetric Modulated Arc Therapy (VMAT). METHODS: From September 2011 to April 2016, 1100 Breast Cancer (BC) patients were referred to our institution to receive adjuvant breast RT, and those with SBBC were selected for the present analysis. A total of 16 patients were identified...
June 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28203178/a-patient-with-supraclavicular-lymphadenopathy-and-anterior-mediastinal-mass-presenting-as-a-rare-case-of-composite-lymphoma-a-case-report-and-literature-review
#20
Alex Raufi, James Jerkins, Yung Lyou, Deepa Jeyakumar
Composite lymphoma (CL) is a rare disease with 2 distinct lymphomas concurrently arising in a single patient with an estimated incidence of 1-4.7% of newly diagnosed lymphomas per year. CL most commonly involves 2 B-cell non-Hodgkin lymphomas (NHL) or a B-cell NHL with a Hodgkin lymphoma. Our case is unique in that it was a bilineage CL with both a T-cell and B-cell NHL, which has only been reported in a few case reports. A 49-year-old woman presented with several months of progressive cough, weight loss, dyspnea, and supraclavicular lymphadenopathy...
September 2016: Case Reports in Oncology
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