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https://www.readbyqxmd.com/read/29675995/bridging-the-hiv-treatment-gap-in-nigeria-examining-community-antiretroviral-treatment-models
#1
Edward A Oladele, Okikiolu A Badejo, Christopher Obanubi, Emeka F Okechukwu, Ezekiel James, Golden Owhonda, Onuche I Omeh, Moyosola Abass, Olubunmi R Negedu-Momoh, Norma Ojehomon, Dorothy Oqua, Satish Raj-Pandey, Hadiza Khamofu, Kwasi Torpey
INTRODUCTION: Significant gaps persist in providing HIV treatment to all who are in need. Restricting care delivery to healthcare facilities will continue to perpetuate this gap in limited resource settings. We assessed a large-scale community-based programme for effectiveness in identifying people living with HIV and linking them to antiretroviral treatment. METHODS: A retrospective secular trend study of 14 high burden local government areas of Nigeria was conducted in which two models of community antiretroviral treatment delivery were implemented: Model A (on-site initiation) and Model B (immediate referral) clusters...
April 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29675618/seq-ing-answers-uncovering-the-unexpected-in-global-gene-regulation
#2
REVIEW
George Maxwell Otto, Gloria Ann Brar
The development of techniques for measuring gene expression globally has greatly expanded our understanding of gene regulatory mechanisms in depth and scale. We can now quantify every intermediate and transition in the canonical pathway of gene expression-from DNA to mRNA to protein-genome-wide. Employing such measurements in parallel can produce rich datasets, but extracting the most information requires careful experimental design and analysis. Here, we argue for the value of genome-wide studies that measure multiple outputs of gene expression over many timepoints during the course of a natural developmental process...
April 19, 2018: Current Genetics
https://www.readbyqxmd.com/read/29673467/transition-intervention-for-adolescents-with-congenital-heart-disease
#3
Andrew S Mackie, Gwen R Rempel, Adrienne H Kovacs, Miriam Kaufman, Kathryn N Rankin, Ahlexxi Jelen, Maryna Yaskina, Renee Sananes, Erwin Oechslin, Dimi Dragieva, Sonila Mustafa, Elina Williams, Michelle Schuh, Cedric Manlhiot, Samantha J Anthony, Joyce Magill-Evans, David Nicholas, Brian W McCrindle
BACKGROUND: There is little evidence regarding the efficacy of interventions to prepare adolescents with congenital heart disease (CHD) to enter adult care. OBJECTIVES: The goal of this study was to evaluate the impact of a nurse-led transition intervention on lapses between pediatric and adult care. METHODS: A cluster randomized clinical trial was conducted of a nurse-led transition intervention for 16- to 17-year-olds with moderate or complex CHD versus usual care...
April 24, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29672608/psychosocial-interventions-for-rehabilitation-and-reintegration-into-daily-life-of-pediatric-cancer-survivors-and-their-families-a-systematic-review
#4
Mona Leandra Peikert, Laura Inhestern, Corinna Bergelt
BACKGROUND: The survival rate of childhood cancer patients increased over the past decades. However, even after successful treatment the transition back to normalcy is often a major challenge for the whole family. Therefore, this study aims to provide an overview of psychosocial interventions for childhood cancer survivors and their families in the first years after the end of cancer treatment. METHODS: We conducted a systematic review following the PRISMA Checklist (Preferred Reporting Items for Systematic Reviews and Meta-Analyses; PROSPERO registration number: CRD42017059782)...
2018: PloS One
https://www.readbyqxmd.com/read/29672162/coyot1-clinic-home-telemedicine-increases-young-adult-engagement-in-diabetes-care
#5
Mark W Reid, Subramanian Krishnan, Cari Berget, Cindy Cain, John Fred Thomas, Georgeanna J Klingensmith, Jennifer K Raymond
BACKGROUND: Young adults with type 1 diabetes (T1D) experience poor glycemic control, disengagement in care, and are often lost to the medical system well into their adult years. Diabetes providers need a new approach to working with the population. The goal of this study was to determine whether an innovative shared telemedicine appointment care model (CoYoT1 Clinic [pronounced as "coyote"; Colorado Young Adults with T1D]) for young adults with T1D improves care engagement, satisfaction, and adherence to American Diabetes Association (ADA) guidelines regarding appointment frequency...
April 19, 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29671012/-cystinosis-diagnosis-cystine-depleting-therapy-and-transition
#6
REVIEW
Jessica Kaufeld, Lutz T Weber, Christine Kurschat, Sima Canaan-Kuehl, Eva Brand, Jun Oh, Lars Pape
This article presents a case of cystinosis in a young man. Diagnosis of the disease and the problem of transition to adult care are described. Cystinosis is a rare lysosomal storage disease with first manifestation in early childhood presenting as renal Fanconi syndrome. Without treatment, the disease leads to severe health impairment. Due to the rarity of the disease, a correct diagnosis is often delayed. Without treatment, cystinosis often leads to end-stage renal failure, blindness, hypothyroidism, diabetes mellitus, and rickets...
April 18, 2018: Der Internist
https://www.readbyqxmd.com/read/29669085/reducing-opioid-use-for-patients-with-chronic-pain-an-evidence-based-perspective
#7
Sarah Wenger, Jason Drott, Rebecca Fillipo, Alyssa Findlay, Amanda Genung, Jessica Heiden, Joke Bradt
The implementation of recent Centers for Disease Control and Prevention recommendations to move away from opioids and toward nonpharmacological therapies for the treatment of chronic pain could involve a difficult transition period for patients and practitioners. The focus of treatment should shift from eliminating pain completely to minimizing the impact of pain on quality of life. Many patients with chronic pain take opioids either because opioids were previously prescribed as a first-line treatment for chronic pain, on the basis of old standards of care, or because opioids were initially prescribed for acute pain...
May 1, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29668145/-lost-in-transition-crossed-looks-on-the-18-25-years-old
#8
Sarah Depallens, Yusuke Leo Takeuchi, Katherine Roberts
Social determinants have an impact on patients' access to care and on their health at any age. Young adults are a population at risk of being affected in their health because of a lack of social protection or unavailability of healthcare system adapted to their specific needs. Primary healthcare providers need to identify that window of social vulnerability in order to avoid a discontinuation in healthcare and to prevent biopsychosocial co-morbidity leading to ongoing consequences on their health.
April 18, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29668144/-majority-in-asylum-seekers-and-unaccompanied-minors-practical-aspects-for-an-effective-inter-professional-approach
#9
Thomas Pernin, Dagmar M Haller, Anne Meynard, Françoise Narring
An unaccompanied minor is a young person under 18 years of age separated from both parents and who is not cared for by an adult invested of this responsability by law or the custom. Their number has increased in Switzerland in 2015, prompting medical and social professionals to adapt their care to respond more appropriately to their needs. Specific elements of an initial health check for these young people, transcultural skills and a good knowledge of the network are necessary to provide optimal management...
April 18, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29667178/cost-utility-analysis-of-bariatric-surgery
#10
O Borisenko, V Lukyanov, A R Ahmed
BACKGROUND: The objective of the study was to evaluate the cost-utility of bariatric surgery in England. METHODS: A state-transition Markov model was developed to compare the costs and outcomes of two treatment approaches for patients with morbid obesity: bariatric surgery, including gastric bypass, sleeve gastrectomy and adjustable gastric banding; and non-surgical usual care. Parameters of the effectiveness of surgery and complications were informed by data from the UK National Bariatric Surgery Registry, the Scandinavian Obesity Registry and the Swedish Obese Subjects study...
April 17, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29666169/impact-of-transitional-care-on-endocrine-and-anthropometric-parameters-in-prader-willi-syndrome
#11
Anne-Cécile Paepegaey, Muriel Coupaye, Asma Jaziri, Florence Menesguen, Béatrice Dubern, Michel Polak, Jean-Michel Oppert, Maithe Tauber, Graziella Pinto, Christine Poitou
CONTEXT: The transition of patients with Prader-Willi syndrome (PWS) to adult life for medical care is challenging because of multiple comorbidities, including hormone deficiencies, obesity, and cognitive and behavioral disabilities. OBJECTIVE: To assess endocrine management, and metabolic and anthropometric parameters of PWS adults who received (n=31) or not (n=64) transitional care, defined as specialized pediatric care followed by a structured care pathway to a multidisciplinary adult team...
April 17, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29666139/last-year-of-life-study-cologne-lyol-c-protocol-for-a-cross-sectional-mixed-methods-study-to-examine-care-trajectories-and-transitions-in-the-last-year-of-life-until-death
#12
Julia Strupp, Gloria Hanke, Nicolas Schippel, Holger Pfaff, Ute Karbach, Christian Rietz, Raymond Voltz
INTRODUCTION: The last year of life constitutes a particularly vulnerable phase for patients, involving nearly all health and social care structures. Yet, little scientific evidence is available that provides insight into the trajectories including the number and types of care setting transitions, transitions into palliative care and the dying phase. Only few studies have focused on difficulties associated with having to move between health and social care settings in the last year of life, although patients face a significant risk of adverse events...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29666101/solitary-cardiac-metastasis-from-primary-oral-squamous-cell-carcinoma-presenting-as-st-elevation-mi
#13
Hiren Patel, Michael Francke, Heather Stahura, Mohammad El-Hajjar, Joshua Schulman-Marcus
Cardiac metastases from oral squamous cell carcinoma (SCC) are rare, especially in the absence of systemic metastasis. We describe a case of a patient presenting with chest pain and ECG abnormalities concerning for ST-elevation myocardial infarction that eventually was found to have an incidental right ventricular mass on chest CT angiogram. Ultimately, she had an intracardiac echocardiography-assisted biopsy diagnosis of isolated cardiac metastasis from primary oral SCC. The extent of the disease precluded any surgical intervention, and the patient subsequently transitioned to hospice care...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29665720/community-pharmacist-preferences-in-transition-of-care-communications
#14
Mackenzie A Dolan, Chelsea P Renfro, Stefanie P Ferreri, Betsy B Shilliday, Timothy J Ives, Jamie J Cavanaugh
OBJECTIVE: To determine community pharmacist preferences in transition of care (TOC) communications. METHODS: In this cross-sectional study, data were gathered via electronic survey of community pharmacists regarding their preferences for TOC communications. The survey was distributed via email by the North Carolina Board of Pharmacy. Results were analyzed using descriptive statistics. RESULTS: Survey responses were received from 343 community pharmacists (response rate = 6...
January 1, 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29665703/culturally-safe-health-initiatives-for-indigenous-peoples-in-canada-a-scoping-review
#15
Lauren Brooks-Cleator, Breanna Phillipps, Audrey Giles
Background Cultural safety has the potential to improve the health disparities between Indigenous and non-Indigenous Canadians, yet practical applications of the concept are lacking in the literature. Purpose This study aims to identify the key components of culturally safe health initiatives for the Indigenous population of Canada to refine its application in health-care settings. Methods We conducted a scoping review of the literature pertaining to culturally safe health promotion programs, initiatives, services, or care for the Indigenous population in Canada...
January 1, 2018: Canadian Journal of Nursing Research, Revue Canadienne de Recherche en Sciences Infirmières
https://www.readbyqxmd.com/read/29665695/women-in-rural-family-medicine-a-qualitative-exploration-of-practice-attributes-that-promote-physician-satisfaction
#16
Carol Hustedde, Heather Paladine, Andrea Wendling, Rupa Prasad, Orlando Sola, Sarah Bjorkman, Julie Phillips
INTRODUCTION: The USA needs more rural physicians. Although women represent half of all US trained medical students, the rural physician workforce has remained predominantly male. Insight is needed into what makes rural practice attractive for women and which practice characteristics allow women physicians to practice successfully in rural areas. This study's purpose was to examine aspects of the practice environment that impact women physicians' professional satisfaction and commitment to rural medicine...
April 2018: Rural and Remote Health
https://www.readbyqxmd.com/read/29662720/role-of-active-versus-passive-complementary-and-integrative-health-approaches-in-pain-management
#17
David Cosio, Erica Lin
Background: A general conclusion about the treatment of chronic, noncancer pain is that the results from traditional, passive modalities are disheartening. Perhaps this may be due to the propensity of patients to seek out passive versus active treatments. In pain management, active treatments should be the primary focus, with passive interventions as an adjunct. Objective: The current study tested the hypotheses that Veterans would report a greater significant increase in active versus transitional and active versus passive complementary and integrative health (CIH) utilization after completing a formal pain education program...
2018: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
https://www.readbyqxmd.com/read/29661702/adolescent-cancer-patients-perceived-quality-of-cancer-care-the-roles-of-patient-engagement-and-supporting-independence
#18
Elizabeth J Siembida, Nina S Kadan-Lottick, Kerry Moss, Keith M Bellizzi
OBJECTIVES: A lack of focus on variation in engagement among cancer populations of differing developmental stages led us to examine the associations between patient engagement, the patient-provider relationship, cognitive development, readiness to transition to adulthood (transitional readiness) and perceived quality of care. METHODS: A sample of 101 adolescent cancer patients (diagnosed 10-20 years) completed survey items concerning patient engagement, dimensions of the patient-provider relationship, cognitive development, transitional readiness, and demographic characteristics using an iPad/tablet during a routine clinic visit...
April 10, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29661107/implementation-of-health-information-exchange-at-the-pima-county-adult-detention-complex-lessons-learned
#19
Alyssa Hinchman, Sara Hodges, James Backus, Terri Warholak
Successful transition of patients between health care entities is difficult. Historically, the process of transitioning individuals through the corrections system with regard to health care was made even more challenging by the limitation of paper records. Recently, the advent of electronic medical records has improved health care nationwide. The use of health information exchange (HIE) systems in areas such as emergency medicine has also impacted patient outcomes. To date, this technology has not been used in the corrections system...
April 2018: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/29660967/a-call-for-implementing-preferred-practices-for-brain-injury-screening-in-youth-to-improve-transition
#20
Drew A Nagele, Melissa McCart, Stephen R Hooper
BACKGROUND: It is vital to engage in systematic screening to identify and serve children who may have sustained an acquired brain injury (ABI) - either traumatic or non-traumatic, so they can be successfully transitioned between environments and life stages. This is particularly important for children and adolescents given the impact an ABI can have on learning and social functioning over the course of the neurodevelopmental process. A pattern of repeated, undiagnosed mild brain injuries may lead to mood or behavior disorders, learning problems...
April 7, 2018: NeuroRehabilitation
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