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https://www.readbyqxmd.com/read/28764168/drug-resistance-pattern-in-the-recent-isolates-of-salmonella-typhi-with-special-reference-to-cephalosporins-and-azithromycin-in-the-gangetic-plain
#1
Shesh Raj Patel, Sujit Bharti, Chandra Bhan Pratap, Gopal Nath
INTRODUCTION: Typhoid fever is an endemic disease in India against which many antibiotics are available. In the recent times, emerging resistance to traditional antibiotics, such as Ampicillin, Chloramphenicol and Trimethoprim/sulfamethoxazole, Azithro-mycin and third generation Cephalosporins are being reported and increasingly being used in the treatment of invasive Salmonella infections. However, the latter two drugs have been reported with occasional clinical failures. Currently, we do not have data regarding their drug resistance levels in the recent isolates of Salmonella enterica subspecies enterica serotype Typhi...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28717307/traditional-treatment-of-human-and-animal-salmonelloses-in-southern-benin-knowledge-of-farmers-and-traditherapists
#2
T V Dougnon, E Déguénon, L Fah, B Lègba, Y M G Hounmanou, J Agbankpè, A Amadou, H Koudokpon, K Fabiyi, A Aniambossou, P Assogba, E Hounsa, M de Souza, F Avlessi, T J Dougnon, F Gbaguidi, M Boko, H S Bankolé, L Baba-Moussa
AIM: This study aimed to report medicinal plants that are likely to be used in the control of salmonellosis. MATERIALS AND METHODS: A cross-sectional study was conducted in Southern Benin. Semi-structured questionnaires were administered to 150 farmers and 100 traditional therapists in seven high municipalities. This step helped to collect plants that are used in the treatment of animal salmonellosis and typhoid fever in human. RESULTS: The results revealed a low level of use of medicinal plants among breeders who prefer antibiotics such as oxytetracycline (53...
June 2017: Veterinary World
https://www.readbyqxmd.com/read/28676794/bacteriophages-contribute-to-the-spread-of-antibiotic-resistance-genes-among-foodborne-pathogens-of-the-enterobacteriaceae-family-a-review
#3
REVIEW
Anna Colavecchio, Brigitte Cadieux, Amanda Lo, Lawrence D Goodridge
Foodborne illnesses continue to have an economic impact on global health care systems. There is a growing concern regarding the increasing frequency of antibiotic resistance in foodborne bacterial pathogens and how such resistance may affect treatment outcomes. In an effort to better understand how to reduce the spread of resistance, many research studies have been conducted regarding the methods by which antibiotic resistance genes are mobilized and spread between bacteria. Transduction by bacteriophages (phages) is one of many horizontal gene transfer mechanisms, and recent findings have shown phage-mediated transduction to be a significant contributor to dissemination of antibiotic resistance genes...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28674312/molecular-subtyping-of-salmonella-enterica-serovar-typhi-by-pulsed-field-gel-electrophoresis-and-multiple-locus-variable-number-tandem-repeat-analysis-in-india-their-association-with-antimicrobial-resistance-profiles
#4
Surojit Das, Sriparna Samajpati, Indranil Roy, Sathish Sankar, Rajni Gaind, Monorama Deb, Raghavendra Kulkarni, Dilip Kumar Paul, Shanta Dutta
Molecular subtyping, and recently DNA sequencing based methods, which are commonly used for discriminating Salmonella enterica serovar Typhi (S. Typhi) isolates, leads to improved molecular epidemiological investigations for prevention and control of typhoid fever. We included S. Typhi blood isolates (n=66) from India during 2007-14 for molecular subtyping by pulsed-field gel electrophoresis (PFGE) and multiple-locus variable-number tandem-repeat (VNTR) analysis (MLVA) in association with antibiotic resistance profiles...
July 1, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28658831/enteric-cholestatic-hepatitis-with-ascites-a-rare-entity
#5
Samarth Virmani, Rama Bhat, Raghavendra Rao, Savio Dsouza, Nitin Bhat
Typhoid fever is a very common illness in developing countries. Patients most often present with a history of fever, vomiting, anorexia, abdominal pain, etc. Rarely there is hepatic involvement due to the disease process. This is a case report of a 26-year-old male who had presented with fever, jaundice and ascites. The widal titres were found to be within normal limits (1:80) however the patient was found to have Salmonella typhi on ascitic fluid culture. The patient was treated with the appropriate antibiotics and was later discharged...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28640809/development-of-elisas-for-diagnosis-of-acute-typhoid-fever-in-nigerian-children
#6
COMPARATIVE STUDY
Jiin Felgner, Aarti Jain, Rie Nakajima, Li Liang, Algis Jasinskas, Eduardo Gotuzzo, Joseph M Vinetz, Fabio Miyajima, Munir Pirmohamed, Fatimah Hassan-Hanga, Dominic Umoru, Binta Wudil Jibir, Safiya Gambo, Kudirat Olateju, Philip L Felgner, Stephen Obaro, D Huw Davies
Improved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ELISAs using Salmonella enterica serovar Typhi (S. Typhi) lipopolysaccharide (LPS) and hemolysin E (t1477) protein were conducted on 86 Nigerian pediatric TF and 29 non-typhoidal Salmonella (NTS) cases, 178 culture-negative febrile cases, 28 "other" (i.e., non-Salmonella) pediatric infections, and 48 healthy Nigerian children...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28591163/strong-influence-of-livestock-environments-on-the-emergence-and-dissemination-of-distinct-multidrug-resistant-phenotypes-among-the-population-of-non-typhoidal-salmonella
#7
Ran An, Sahar Alshalchi, Peter Breimhurst, Jeannette Munoz-Aguayo, Christian Flores-Figueroa, Sinisa Vidovic
The problem of emergence and dissemination of multidrug resistance, especially among Gram-negative bacteria, has reached alarming levels. This increases the need to develop surveillance methods that more effectively and accurately provide information about the emergence and spread of multidrug-resistant organisms. In this study, using a well-defined population of non-typhoidal Salmonella (NTS) isolates associated with avian, bovine and porcine hosts, we found that the livestock environments had a specific (P < 0...
2017: PloS One
https://www.readbyqxmd.com/read/28560124/multidrug-resistant-invasive-nontyphoidal-salmonella-isolated-from-and-masquerading-healed-tubercular-constrictive-pericarditis-and-study-of-virulence-markers
#8
Reetika Dawar, Anoop Ganjoo, Firdaus Imdadi, Vasundhra Bhandari
Among the infectious causes of pericarditis are various bacteria, viruses, fungal and parasitic infections. The course disease may progress to a chronic constrictive pattern especially with tubercular etiology. Non-typhoidal Salmonella has rarely been reported as a cause of pericarditis. We describe here a case from which the pericardial fluid from an old case of tubercular pericarditis sent for culture to microbiology laboratory grew a Salmonella typhimurium. We studied the antibiotic resistance pattern, phage type and virulence factors playing a role in the invasive nature of the pathogen since no such study from pericardial fluid was found in the literature...
April 26, 2017: Curēus
https://www.readbyqxmd.com/read/28556448/non-typhoidal-salmonella-infections-in-children-review-of-literature-and-recommendations-for-management
#9
REVIEW
Sophie Ch Wen, Emma Best, Clare Nourse
Non-typhoidal Salmonellae are a major cause of infectious diarrhoea worldwide and can cause invasive diseases, including bacteraemia, meningitis and osteomyelitis. Young or immunocompromised children and those with underlying conditions such as sickle cell disease are particularly vulnerable to invasive disease. There has been an increase in the rate of resistant non-typhoidal Salmonella, which is associated with invasive disease and hospitalisation. The intracellular nature of non-typhoidal Salmonella protects against extracellular antibiotics and can facilitate disease relapse, particularly meningitis...
May 29, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28546075/antimicrobial-storage-and-antibiotic-knowledge-in-the-community-a-cross-sectional-pilot-study-in-north-western-angola
#10
Joana Cortez, Edite Rosário, João E Pires, João Taborda Lopes, Moisés Francisco, Erika Vlieghe, Miguel Brito
BACKGROUND: Antimicrobials are drugs that were once lifesavers and mainly curative. Nowadays their value is increasingly under pressure because of the rapid and worldwide emergence of antimicrobial resistance, which, in low-resource settings, frequently occurs in microorganisms that are likely to be transmitted in the community. METHODS: This was a cross-sectional pilot study including 102 households within the 10th Health and Demographic Surveillance System round in Dande, Bengo Province, Angola...
July 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28544285/salmonella-typhi-genomics-envisaging-the-future-of-typhoid-eradication
#11
REVIEW
Kien-Pong Yap, Kwai Lin Thong
Next-generation whole-genome sequencing has revolutionised the study of infectious diseases in recent years. The availability of genome sequences and its understanding have transformed the field of molecular microbiology, epidemiology, infection treatments and vaccine developments. We review the key findings of the publicly accessible genomes of Salmonella enterica serovar Typhi since the first complete genome to the most recent release of thousands of Salmonella Typhi genomes, which remarkably shape the genomic research of S...
August 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28520997/resistant-pathogens-as-causes-of-traveller-s-diarrhea-globally-and-impact-s-on-treatment-failure-and-recommendations
#12
David R Tribble
Background: : Diarrhea is a frequent clinical syndrome affecting international travellers. Bacterial etiologic agents have a long history of emergent antimicrobial resistance against commonly used antibiotics. Current approaches applying first-line antimicrobial therapy are being challenged by increasingly resistant organisms. This review summarizes recent epidemiological and clinical evidence of antibiotic resistance among enteropathogens causing traveller's diarrhea and the subsequent impact on current treatment recommendations...
April 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28515625/overview-of-the-impact-of-typhoid-and-paratyphoid-fever-utility-of-ty21a-vaccine-vivotif%C3%A2
#13
REVIEW
D Amicizia, L Arata, F Zangrillo, D Panatto, R Gasparini
Cases of diarrhoeal disease number from 1.7 to 5 billion per year worldwide. One of the main causes of diarrhoeal disease is typhoid fever, which is a potentially life-threatening multi-systemic illness. According to the most recent estimates, a total of 26.9 million typhoid fever episodes occurred in 2010. The geographical distribution of the disease differs widely; in developed countries, the incidence rate per 100,000 per year varies from < 0.1 to 0.3, and the disease mainly affects people who travel to endemic areas located in low- and middle-income countries...
March 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/28481935/genotypic-and-phenotypic-characterization-of-multidrug-resistant-salmonella-typhimurium-and-salmonella-kentucky-strains-recovered-from-chicken-carcasses
#14
Rizwana Tasmin, Nur A Hasan, Christopher J Grim, Ar'Quette Grant, Seon Young Choi, M Samiul Alam, Rebecca Bell, Christopher Cavanaugh, Kannan V Balan, Uma S Babu, Salina Parveen
Salmonella Typhimurium is the leading cause of human non-typhoidal gastroenteritis in the US. S. Kentucky is one the most commonly recovered serovars from commercially processed poultry carcasses. This study compared the genotypic and phenotypic properties of two Salmonella enterica strains Typhimurium (ST221_31B) and Kentucky (SK222_32B) recovered from commercially processed chicken carcasses using whole genome sequencing, phenotype characterizations and an intracellular killing assay. Illumina MiSeq platform was used for sequencing of two Salmonella genomes...
2017: PloS One
https://www.readbyqxmd.com/read/28480295/variation-in-tularemia-clinical-manifestations-arkansas-2009-2013
#15
Laura K Lester Rothfeldt, Richard F Jacobs, J Gary Wheeler, Susan Weinstein, Dirk T Haselow
BACKGROUND: Francisella tularensis, although naturally occurring in Arkansas, is also a Tier 1 select agent and potential bioterrorism threat. As such, tularemia is nationally notifiable and mandatorily reported to the Arkansas Department of Health. We examined demographic and clinical characteristics among reported cases and outcomes to improve understanding of the epidemiology of tularemia in Arkansas. METHODS: Surveillance records on all tularemia cases investigated during 2009-2013 were reviewed...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28373758/typhoid-intestinal-perforation-in-developing-countries-still-unavoidable-deaths
#16
EDITORIAL
Sandro Contini
Typhoid fever is a public health challenge mostly concentrated in impoverished, overcrowded areas of the developing world, with lack of safe drinking and sanitation. The most serious complication is typhoid intestinal perforation (TIP), observed in 0.8% to 39%, with a striking rate difference between high-income and low-middle-income countries. Although the mortality rate consequent to TIP in resource-poor countries is improved in the last decades, it is still fluctuating from 5% to 80%, due to surgical- and not surgical-related constraints...
March 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28344395/characterization-of-salmonella-gallinarum-from-an-outbreak-in-raigarh-chhattisgarh
#17
Chandrahas Sannat, Anil Patyal, Nidhi Rawat, R C Ghosh, D K Jolhe, R K Shende, S D Hirpurkar, Sanjay Shakya
AIM: The present investigation was conducted to isolate and characterize Salmonella Gallinarum from an outbreak of fowl typhoid in layer birds. MATERIALS AND METHODS: Clinically ill and dead layer birds from an outbreak were investigated. History, clinical signs, and postmortem lesions were suggestive of fowl typhoid. Postmortem samples including heart blood, intestinal contents, pieces of ovary, and liver were collected and processed immediately for bacterial culture, serotyping and antibiotic sensitivity tests...
February 2017: Veterinary World
https://www.readbyqxmd.com/read/28277779/further-investigations-on-the-epidemiology-of-fowl-typhoid-in-brazil
#18
Anny Lucia Del Pilar Celis-Estupiñan, Diego Felipe Alves Batista, Marita Vedovelli Cardozo, Andrei Itajahy Secundo de Souza, Lucas Bocchini Rodrigues Alves, Adriana Maria de Almeida, Paul Andrew Barrow, Angelo Berchieri, Oliveiro Caetano de Freitas Neto
Salmonella Gallinarum (SG) causes fowl typhoid (FT), a disease responsible for economic losses to the poultry industry worldwide. FT has been considered to be under control in Brazil; nevertheless, since 2012 it has frequently been identified in poultry farming of several Brazilian states. The present study was aimed at assessing (i) the pathogenicity of a SG strain recently isolated from an FT outbreak affecting chickens of both white and brown layers; (ii) the transmission of SG through eggs and hatching; (iii) the effects of antibiotic therapy on SG persistence in poultry tissues and on its vertical transmission and (iv) the genetic profiles of strains isolated over 27 years by Pulsed Field Gel Electrophoresis...
April 13, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28260765/comparison-of-molecular-detection-method-nested-polymerase-chain-reaction-with-blood-culture-and-paired-widal-test-for-the-rapid-diagnosis-of-typhoid-fever
#19
S Khan, R A Miah, S Pal, S Khatun, N Fatema, R R Roy, C R Naheen
Typhoid fever is a major health problem in developing countries in spite of the use of antibiotics and the development of newer antibacterial drugs. Blood culture & serological tests (specially Widal test) which are invariably done in Bangladesh for typhoid fever diagnosis give unacceptable levels of false negative & false positive results respectively. This cross sectional study was done at Bangabandhu Sheikh Mujib Medical University from March 2013 to February 2014. In this study, a polymerase chain reaction-based technique (which has 100% specificity for Salmonella Typhi) was compared with blood culture and widal test among 80 clinically suspected cases of typhoid fever...
January 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28248674/prevalence-serotype-distribution-and-antimicrobial-resistance-of-salmonella-isolated-from-food-products-in-morocco
#20
Nadia Amajoud, Brahim Bouchrif, Mohammed El Maadoudi, Nadia Skalli Senhaji, Bouchra Karraouan, Abdeltif El Harsal, Jamal El Abrini
INTRODUCTION: Salmonellosis is one of the most common foodborne diseases worldwide. The irrational use of antibiotics in medicine and in animal feed has greatly promoted the emergence and spread of resistant strains of non-typhoidal Salmonella. METHODOLOGY: A total of 464 food products were collected in Tetouan from January 2010 to December 2012. The isolation and identification of Salmonella were performed according to Moroccan standard 08.0.116. All isolates were serotyped and were then tested for antibiotic resistance using the disk diffusion method...
February 28, 2017: Journal of Infection in Developing Countries
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