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https://www.readbyqxmd.com/read/29911409/the-ottawa-panel-guidelines-on-programmes-involving-therapeutic-exercise-for-the-management-of-hand-osteoarthritis
#1
Lucie Brosseau, Odette Thevenot, Olivia MacKiddie, Jade Taki, George A Wells, Paulette Guitard, Guillaume Léonard, Nicole Paquet, Sibel Z Aydin, Karine Toupin-April, Sabrina Cavallo, Rikke Helene Moe, Kamran Shaikh, Wendy Gifford, Laurianne Loew, Gino De Angelis, Shirin Mehdi Shallwani, Ala' S Aburub, Aline Mizusaki Imoto, Prinon Rahman, Inmaculada C Álvarez Gallardo, Milkana Borges Cosic, Nina Østerås, Sabrina Lue, Tokiko Hamasaki, Nathaly Gaudreault, Tanveer E Towheed, Sahil Koppikar, Ingvild Kjeken, Dharini Mahendira, Glen P Kenny, Gail Paterson, Marie Westby, Lucie Laferrière, Guy Longchamp
OBJECTIVE: To identify programmes involving therapeutic exercise that are effective for the management of hand osteoarthritis and to provide stakeholders with updated, moderate to high-quality recommendations supporting exercises for hand osteoarthritis. METHODS: A systematic search and adapted selection criteria included comparable trials with exercise programmes for managing hand osteoarthritis. Based on the evaluated evidence, a panel of experts reached consensus through a Delphi approach endorsing the recommendations...
June 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29910056/rationale-and-design-of-the-seneca-stem-cell-injection-in-cancer-survivors-trial
#2
Roberto Bolli, Joshua M Hare, Timothy D Henry, Carrie G Lenneman, Keith L March, Kathy Miller, Carl J Pepine, Emerson C Perin, Jay H Traverse, James T Willerson, Phillip C Yang, Adrian P Gee, João A Lima, Lem Moyé, Rachel W Vojvodic, Shelly L Sayre, Judy Bettencourt, Michelle Cohen, Ray F Ebert, Robert D Simari
OBJECTIVES: SENECA (StEm cell iNjECtion in cAncer survivors) is a phase I, randomized, double-blind, placebo-controlled study to evaluate the safety and feasibility of delivering allogeneic mesenchymal stromal cells (allo-MSCs) transendocardially in subjects with anthracycline-induced cardiomyopathy (AIC). BACKGROUND: AIC is an incurable and often fatal syndrome, with a prognosis worse than that of ischemic or nonischemic cardiomyopathy. Recently, cell therapy with MSCs has emerged as a promising new approach to repair damaged myocardium...
July 2018: American Heart Journal
https://www.readbyqxmd.com/read/29909357/abdominal-muscle-recruitment-and-its-effect-on-the-activity-level-of-the-hip-and-posterior-thigh-muscles-during-therapeutic-exercises-of-the-hip-joint
#3
Sharon M H Tsang, Amanda H M Lam, Melody H L Ng, Kiki W K Ng, Cherry O H Tsui, Benjamin Yiu
Abdominal exercise has been advocated to improve the protection of the spine and neuromuscular efficiency of the limb movements. The purpose of this study was to examine the effect of enhanced contraction of internal oblique and transversus abdominis (IO/TrA) on the activity level of the hip and posterior thigh muscles during therapeutic hip exercises. Twenty healthy females were required to perform eight hip exercises under two conditions, natural versus enhanced IO/TrA contraction conditions. Muscle activity of gluteus maximus, gluteus medius, tensor fasciae latae and biceps femoris of the exercising leg was measured by surface electromyography during hip exercises, and expressed in percentage normalized to the maximal voluntary isometric contraction (%MVIC)...
June 12, 2018: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29907457/what-may-the-future-hold-for-sports-cardiology
#4
REVIEW
André La Gerche, Aaron Baggish, Hein Heidbuchel, Benjamin D Levine, Dhrubo Rakhit
The field of sports cardiology has advanced significantly over recent times. It has incorporated clinical and research advances in cardiac imaging, electrophysiology and exercise physiology to enable better diagnostic and therapeutic management of our patients. One important endeavour has been to try and better differentiate athletic cardiac remodelling from inherited cardiomyopathies and other pathologies. Whilst our diagnostic tools have improved, there have also been errors resulting from assumptions that the pathological traits observed in the general population would be generalisable to athletic populations...
June 6, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29906737/achilles-tendon-loading-during-weight-bearing-exercises
#5
Naghmeh Gheidi, Thomas W Kernozek, John D Willson, Andrew Revak, Keith Diers
OBJECTIVE: Compare the estimated Achilles tendon (AT) loading using a musculoskeletal model during commonly performed weight bearing therapeutic exercises. DESIGN: Controlled laboratory study. SETTING: University biomechanics laboratory. PARTICIPANTS: Eighteen healthy males (Age:22.1 ± 1.8 years, height:177.7 ± 8.4 cm, weight = 74.29 ± 11.3 kg). MAIN OUTCOME MEASURE(S): AT loading was estimated during eleven exercises: tandem, Romberg, and unilateral standing, unilateral and bilateral heel raising, unilateral and bilateral jump landing, squat, lunge, walking, and running...
May 10, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29904119/wnk1-regulates-skeletal-muscle-cell-hypertrophy-by-modulating-the-nuclear-localization-and-transcriptional-activity-of-foxo4
#6
Shintaro Mandai, Takayasu Mori, Naohiro Nomura, Taisuke Furusho, Yohei Arai, Hiroaki Kikuchi, Emi Sasaki, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida
With-no-lysine (K) (WNK) kinases, which are mutated in the inherited form of hypertension pseudohypoaldosteronism type II, are essential regulators of membrane ion transporters. Here, we report that WNK1 positively regulates skeletal muscle cell hypertrophy via mediating the function of the pro-longevity transcription factor forkhead box protein O4 (FOXO4) independent of the conventional WNK signaling pathway linking SPS/STE20-related proline-alanine-rich kinase (SPAK)/oxidative stress response kinase 1 (OSR1) to downstream effector ion transporters...
June 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29902265/clinical-use-of-submaximal-treadmill-exercise-testing-and-assessments-of-cardiac-biomarkers-nt-probnp-and-ctni-in-dogs-with-presymptomatic-mitral-regurgitation
#7
Leona Wall, Annika Mohr, Florenza Lüder Ripoli, Nayeli Schulze, Camila Duarte Penter, StephanOscar Hungerbuehler, Jan-Peter Bach, Karin Lucas, Ingo Nolte
Exercise intolerance is the first symptom of heart disease. Yet an objective and standardised method in canine cardiology to assess exercise capacity in a clinical setting is lacking. In contrast, exercise testing is a powerful diagnostic tool in humans, providing valuable information on prognosis and impact of therapeutic intervention. To investigate whether an exercise test reveals differences between dogs with early stage mitral regurgitation (MR) and dogs without cardiac disease, 12 healthy beagles (healthy group, HG) and 12 dogs with presymptomatic MR (CHIEF B1 / B2, patient group, PG) underwent a six-stage submaximal exercise test (ET) on a motorised treadmill...
2018: PloS One
https://www.readbyqxmd.com/read/29898875/clinical-and-molecular-markers-in-copd
#8
I Gonçalves, M J Guimarães, M van Zeller, F Menezes, J Moita, P Simão
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease, and there is a clinical need for validated markers and biomarkers that can contribute to the assessment of patients, risk prediction, treatment guidance, and assessment of response. Although according to the 2018 GOLD guidelines clinically useful biomarkers for COPD patients in stable condition have yet to be identified, several clinical markers and biomarkers have been proposed for COPD. These include isolated clinical markers, such as symptoms and Health Status assessment, exercise tests, function tests and imaging, and also composite scores and molecular markers...
June 10, 2018: Pulmonology
https://www.readbyqxmd.com/read/29898649/bpc157-as-potential-agent-rescuing-from-cancer-cachexia
#9
Eun A Kang, Young Min Han, Jeong Min An, Yong Jin Park, Predrag Sikiric, Deok Hwan Kim, Kwang An Kwon, Yoon Jae Kim, Donghwa Yang, Hann Tchah, Ki Baik Hahm
Cancer cachexia, one of the metabolic syndromes caused by cancer, is a devastating and miserable condition encountered in more than 50% of terminal cancer patients presenting with significant weight loss associated with skeletal muscle atrophy and fat loss. Though cachexia may account for up to 20% of cancer deaths, no significant treatment is still lacking and is of urgent unmet medical need in cancer treatment. Therefore, understanding the underlying molecular mechanisms is essential for anticipating therapeutic approaches...
June 13, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29891249/differentiating-athlete-s-heart-from-cardiomyopathies-the-left-side
#10
Maria J Brosnan, Dhrubo Rakhit
In athletes who undertake a high volume of high intensity exercise, the resultant changes in cardiac structure and function which develop as a result of physiological adaptation to exercise (so called "Athlete's Heart") may overlap with some features of pathological conditions. This chapter will focus on the left side of the heart, where left ventricular cavity enlargement, increase in left ventricular wall thickness and increased left ventricular trabeculation associated with athletic remodelling may sometimes be difficult to differentiate from conditions such as dilated cardiomyopathy, hypertrophic cardiomyopathy or isolated left ventricular non-compaction...
May 16, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29889599/pain-management-using-a-multimodal-physiotherapy-program-including-a-biobehavioral-approach-for-chronic-nonspecific-neck-pain-a-randomized-controlled-trial
#11
Ibai López-de-Uralde-Villanueva, Hector Beltran-Alacreu, Josué Fernández-Carnero, Roy La Touche
OBJECTIVE: To determine the effectiveness of a therapeutic patient education (TPE) intervention based on a biobehavioral approach combined with manual therapy (MT) to reduce pain in patients with chronic nonspecific neck pain (CNSNP). In addition, this study intended to assess the effectiveness of a multimodal physiotherapy program including TPE to reduce pain in patients with CNSNP. DESIGN: Single-blind randomized controlled trial. INTERVENTIONS: A total of 47 patients with CNSNP were randomized into three groups: (1) MT (control group); (2) MT plus TPE based on a biobehavioral approach (Exp1); and (3) MT plus TPE based on a biobehavioral approach, and therapeutic exercise (Exp2)...
June 11, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29889141/interaction-between-foods-and-nonsteroidal-anti-inflammatory-drugs-and-exercise-in-the-induction-of-anaphylaxis
#12
Joan Bartra, Giovanna Araujo, Rosa Muñoz-Cano
PURPOSE OF REVIEW: To assess the studies that focus on the study of food-dependent exercise-induced anaphylaxis (FDEIA) and food-dependent NSAID-induced anaphylaxis (FDNIA). RECENT FINDINGS: Cofactors, as exercise and nonsteroidal anti-inflammatory drugs (NSAIDs), are relevant in up to 30% of episodes of anaphylaxis. Gliadin and lipid transfer proteins are the main allergens involved. The attempts to reproduce FDEIA and FDNIA in a controlled setting have an important failure rate...
June 7, 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29889057/effects-of-assisted-sit-up-exercise-compared-to-core-stabilization-exercise-on-patients-with-non-specific-low-back-pain-a-randomized-controlled-trial
#13
Cho-Rong Bae, Yan Jin, Bum-Chul Yoon, Nack-Hwan Kim, Kun-Woo Park, Sang-Heon Lee
BACKGROUND: Traditional sit-up exercise is a simple method to strengthen core muscles. However, it can increase the potential of lumbar spine injury during the bending process. OBJECTIVE: To evaluate the effect of assisted sit-up exercise (SUE) using a new training device, HubEX-LEX, on strengthening core muscles and improving non-specific low back pain (NSLBP) compared to conventional core stabilization exercise (CSE). METHODS: Subjects with chronic NSLBP were randomly divided into two groups: SUE (n= 18) or CSE (n= 18)...
May 26, 2018: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29888581/-acupuncture-treatment-of-polycystic-ovarian-syndrome-patients-with-abdominal-obesity-by-regulating-dai-meridian-a-randomized-controlled-clinical-trial
#14
Ling-Yu Shen, Cui-Mei Liang, Wen-Jin Yang, Liang Pan, Hua Li, Hui Hu
OBJECTIVE: To explore the therapeutic effect of acupuncture in the treatment of polycystic ovarian syndrome (PCOS) patients with abdominal obesity by regulating glucose metabolism, insulin resistance, sex hormones, etc. METHODS: Eligible PCOS volunteers were randomly divided into treatment group( n =30) and control group( n =28). The treatment group received acupuncture therapy three times a week combined with diet control and exercise. EA (2 Hz/100 Hz, 4-8 mA) was applied to bilateral Daimai (GB 26)and Tianshu (ST 25) for 20 min/time, and bilateral Daheng (SP 15), Shenshu (BL 23), Ciliao (BL 32), Guilai (ST 29), Zulinqi (GB 41) and Waiguan (SJ 5) were stimulated with filiform needles, with the needles retained for 20 min...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29887681/effect-of-add-on-yoga-on-cognitive-functions-among-substance-abusers-in-a-residential-therapeutic-center-randomized-comparative-study
#15
Ananda Gaihre, Sasidharan K Rajesh
Background: Chronic vulnerability characterizes substance abuse disorder with consequent relapse. The process of abstinence depends on cognitive recovery. Hence, behavioral intervention should account for cognitive dimension of substance abusers. Recent studies highlight yoga-based intervention as a promising add-on therapy for treating and preventing addictive behaviors. Purpose: The study aimed to evaluate the efficacy of a yoga-based intervention as an add-on in enhancing cognitive functions, compared with physical exercise to newly admitted substance abusers seeking an inpatient treatment program...
April 2018: Annals of Neurosciences
https://www.readbyqxmd.com/read/29885311/effectiveness-of-supervised-home-based-exercise-therapy-compared-to-a-control-intervention-on-functions-activities-and-participation-in-older-patients-after-hip-fracture-a-systematic-review-and-meta-analysis
#16
REVIEW
Isolde A R Kuijlaars, Lieke Sweerts, Maria W G Nijhuis-van der Sanden, Romke van Balen, J Bart Staal, Nico L U van Meeteren, Thomas J Hoogeboom
OBJECTIVE: The aim of this review was to investigate whether supervised home-based exercise therapy after hospitalization is more effective on improving functions, activities and participation in older patients after hip fracture as compared with a control intervention (including usual care). Furthermore, we aimed to account the body of evidence for therapeutic validity. DATA SOURCES: Systematic searches of Medline, Embase and CINAHL databases up to 30 June 2016...
June 6, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29884720/acyclovir-induced-thrombocytopaenia-in-a-patient-with-sle
#17
Irene Tsappa, Constantinos Missouris, Savvas Psarellis
Acyclovir has been used in the treatment of herpes simplex and varicella zoster viral infections for over 30 years. The side effects of oral treatment at standard doses are rare and include headache, diarrhoea, dizziness and malaise. We report a patient with a new diagnosis of systemic lupus erythematosus (SLE) who developed thrombocytopaenia within days on a therapeutic dose with acyclovir. Prompt discontinuation of acyclovir and treatment with intravenous immunoglobulin resulted in reversal of the above potentially serious complication...
June 8, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29882074/the-effectiveness-of-exercise-based-interventions-for-preventing-or-treating-postpartum-depression-a-systematic-review-and-meta-analysis
#18
REVIEW
Tim Carter, Anastasios Bastounis, Boliang Guo, C Jane Morrell
Postpartum depression can have detrimental effects on both a mother's physical and mental health and on her child's growth and emotional development. The aim of this study is to assess the effectiveness of exercise/physical activity-based interventions in preventing and treating postpartum depressive symptoms in primiparous and multiparous women to the end of the postnatal period at 52 weeks postpartum. Electronic databases were searched for published and unpublished randomised controlled trials of exercise/physical activity-based interventions in preventing and treating depressive symptoms and increasing health-related quality of life in women from 4 to 52 weeks postpartum...
June 7, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29879638/blood-flow-restriction-induces-hypoalgesia-in-recreationally-active-adult-male-anterior-knee-pain-patients-allowing-therapeutic-exercise-loading
#19
Vasileios Korakakis, Rodney Whiteley, Konstantinos Epameinontidis
OBJECTIVE: To evaluate if a single blood flow restriction (BFR)-exercise bout would induce hypoalgaesia in patients with anterior knee pain (AKP) and allow painless application of therapeutic exercise. DESIGN: Cross-sectional repeated measures design. SETTING: Institutional out-patients physiotherapy clinic. PATIENTS: Convenience sample of 30 AKP patients. INTERVENTION: BFR was applied at 80% of complete vascular occlusion...
May 31, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29875684/efficacy-and-safety-of-low-frequency-whole-body-electromyostimulation-wb-ems-to-improve-health-related-outcomes-in-non-athletic-adults-a-systematic-review
#20
Wolfgang Kemmler, Anja Weissenfels, Sebastian Willert, Mahdieh Shojaa, Simon von Stengel, Andre Filipovic, Heinz Kleinöder, Joshua Berger, Michael Fröhlich
Exercise positively affects most risk factors, diseases and disabling conditions of middle to advanced age, however the majority of middle-aged to older people fall short of the exercise doses recommended for positively affecting cardio-metabolic, musculoskeletal and neurophysiological fitness or disabling conditions. Whole-Body Electromyostimulation (WB-EMS) may be a promising exercise technology for people unable or unmotivated to exercise conventionally. However, until recently there has been a dearth of evidence with respect to WB-EMS-induced effects on health-related outcomes...
2018: Frontiers in Physiology
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