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https://www.readbyqxmd.com/read/29456629/acute-vitamin-c-improves-cardiac-function-not-exercise-capacity-in-adults-with-type-2-diabetes
#1
Rebecca L Scalzo, Timothy A Bauer, Kylie Harrall, Kerrie Moreau, Cemal Ozemek, Leah Herlache, Shawna McMillin, Amy G Huebschmann, Jennifer Dorosz, Jane E B Reusch, Judith G Regensteiner
Background: People with type 2 diabetes (T2D) have impaired exercise capacity, even in the absence of complications, which is predictive of their increased cardiovascular mortality. Cardiovascular dysfunction is one potential cause of this exercise defect. Acute infusion of vitamin C has been separately shown to improve diastolic and endothelial function in prior studies. We hypothesized that acute vitamin C infusion would improve exercise capacity and that these improvements would be associated with improved cardiovascular function...
2018: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29455504/-clinical-effects-of-rehabilitation-exercise-in-the-treatment-of-knee-osteoarthritis-based-on-the-theory-of-treating-muscle-for-bone
#2
An Yan, Kuan Zhang, Wei-Kai Qin, Jiang-Zhou Guo, Ling-Hui Li, Ming Chen, Shang-Quan Wang
OBJECTIVE: To study the efficacy and safety of voluntary rehabilitation exercise in the treatment of knee osteoarthritis, based on the traditional Chinese medicine theory of "treating muscle for bone". METHODS: Ninety participants with early knee osteoarthritis were randomly divided into experimental group ( n =45) and control group ( n =45). Patients in experimental group were treated with voluntary rehabilitation exercise combined with isometric extension of quadriceps femoris...
August 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29455497/-clinical-research-of-treating-the-avulsed-fracture-of-humerus-greater-tuberosity-using-an-arthroscopic-double-row-suture-anchor-fixation-technique
#3
Ji Li, Wei-Xiong Liao, Hao Zhang, Yi-Meng Yang, Ke-Tao Wang, Zhong-Li Li
OBJECTIVE: To evaluate the early clinical effects of treating the avulsed fracture of humerus greater tuberosity using the double-row suture anchor fixation technique. METHODS: Total 20 patients with the avulsed fracture of the greater tuberosity of the humerus were treated from September 2009 to January 2013. There were 12 males and 7 females, with an average age of 46.8 years old(24 to 69 years old). Eleven patients had injuries on right shoulder joint and 8 patients had injuries on left side...
August 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29455496/-comparison-of-therapeutic-effects-of-three-repair-methods-for-rotator-cuff-tears-under-arthroscopy
#4
Xiao-Bo Zhou, Jun-Bo Liang, Zhong-Yi Chen
OBJECTIVE: To retrospectively study curative effects of three repair methods for rotator cuff tears under arthroscopy, and to explore relationships between different repair methods and cuff lesions. METHODS: From January 2009 to Jaunary 2014, a total of 353 patients with rotator cuff tears treated with surgical repair under arthroscopy were included in this study. All the patients were divided into three groups according to time of visitiny hospital and it was divided into three periods...
August 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29452779/management-of-female-stress-urinary-incontinence-a-care-pathway-and-update
#5
REVIEW
Giampiero Capobianco, Massimo Madonia, Sonia Morelli, Francesco Dessole, Davide De Vita, Pier Luigi Cherchi, Salvatore Dessole
Stress urinary incontinence (SUI) is a condition characterized by an involuntary loss of urine occurring as result of an increase in intra-abdominal pressure due to effort or exertion or on sneezing or coughing. Estimates of its prevalence in the female population range from 10% to 40%. A literature search of the Medline, Cochrane library, EMBASE, NLH, ClinicalTrials.gov and Google Scholar databases was done up to July 2017, restricted to English-language articles, using terms related to SUI, medical therapy, surgical therapy and treatment options...
March 2018: Maturitas
https://www.readbyqxmd.com/read/29452626/translation-of-an-evidence-based-therapeutic-exercise-program-for-patients-with-peripheral-artery-disease
#6
Dereck L Salisbury, Mary O Whipple, Marsha Burt, Rebecca J L Brown, Alan Hirsch, Christopher Foley, Diane Treat-Jacobson
The purpose of this study was to implement and evaluate quality outcomes including referral, enrollment, and completion rates of a new peripheral artery disease (PAD)-specific supervised exercise therapy (SET) program within a preexisting clinical exercise wellness program and to evaluate the clinical effectiveness and patient-centered outcomes derived from 12 weeks of PAD-specific SET. Recruited participants completed an individualized, minimally supervised, PAD-specific SET program based on the AHA-ACC guidelines...
March 2018: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/29447741/the-burden-of-iron-deficiency-in-heart-failure-therapeutic-approach
#7
REVIEW
Bruno M L Rocha, Gonçalo J L Cunha, Luiz F Menezes Falcão
Heart failure (HF) is highlighted by its burdening symptom-limited exercise capacity and recurrent hospitalizations. Despite substantial advances regarding disease-modifying drugs in HF with reduced ejection fraction, additional therapeutic strategies to improve quality of life are invaluable. Currently, iron deficiency (ID) is overwhelmingly recognized in over 30% to 50% of patients with stable chronic HF, which worsens prognosis. The established pathophysiological mechanisms of progressive HF may be intertwined with increasing myocardial iron scarcity, wherein one begets the other...
February 20, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29447080/improved-lower-extremity-pedaling-mechanics-in-individuals-with-stroke-under-maximal-workloads
#8
Susan M Linder, Anson B Rosenfeldt, Andrew S Bazyk, Mandy Miller Koop, Sarah Ozinga, Jay L Alberts
Background Individuals with stroke present with motor control deficits resulting in the abnormal activation and timing of agonist and antagonist muscles and inefficient movement patterns. The analysis of pedaling biomechanics provides a window into understanding motor control deficits, which vary as a function of workload. Understanding the relationship between workload and motor control is critical when considering exercise prescription during stroke rehabilitation. Objectives To characterize pedaling kinematics and motor control processes under conditions in which workload was systematically increased to an eventual patient-specific maximum...
February 15, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29443878/skeletal-muscle-pathophysiology-the-emerging-role-of-spermine-oxidase-and-spermidine
#9
REVIEW
Manuela Cervelli, Alessia Leonetti, Guglielmo Duranti, Stefania Sabatini, Roberta Ceci, Paolo Mariottini
Skeletal muscle comprises approximately 40% of the total body mass. Preserving muscle health and function is essential for the entire body in order to counteract chronic diseases such as type II diabetes, cardiovascular diseases, and cancer. Prolonged physical inactivity, particularly among the elderly, causes muscle atrophy, a pathological state with adverse outcomes such as poor quality of life, physical disability, and high mortality. In murine skeletal muscle C2C12 cells, increased expression of the spermine oxidase (SMOX) enzyme has been found during cell differentiation...
February 14, 2018: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29443823/aerobic-training-improves-quality-of-life-in-women-with-polycystic-ovary-syndrome
#10
Eduardo Caldas Costa, Joceline Cássia Ferezini de Sá, Nigel Keith Stepto, Ingrid Bezerra Barbosa Costa, Luiz Fernando Farias-Junior, Simone da Nóbrega Tomaz Moreira, Elvira Maria Mafaldo Soares, Telma Maria Araújo Moura Lemos, Rodrigo Alberto Vieira Browne, George Dantas Azevedo
PURPOSE: To investigate the effects of a supervised aerobic exercise training intervention on health-related quality of life (HRQL), cardiorespiratory fitness, cardiometabolic profile, and affective response in overweight/obese women with polycystic ovary syndrome (PCOS). METHODS: Twenty-seven overweight/obese inactive women with PCOS (body mass index, BMI ≥ 25 kg/m; aged from 18 to 34 years) were allocated into an exercise group (n = 14) and a control group (n = 13)...
February 13, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29441279/externally-applied-compression-therapy-for-fontan-patients
#11
Joseph Hernandez, Steven G Chopski, Sam Lee, William B Moskowitz, Amy L Throckmorton
Background: Limited therapeutic options are available for Fontan patients with dysfunctional or failing single ventricle physiology. This study describes the evaluation of an alternative, non-invasive, at-home therapeutic compression treatment for Fontan patients. Our hypothesis is that routinely administered, externally applied compression treatments to the lower extremities will augment systemic venous return, improve ventricular preload, and thus enhance cardiac output in Fontan patients...
January 2018: Translational Pediatrics
https://www.readbyqxmd.com/read/29440149/cancer-cachexia-rationale-for-the-menac-multimodal-exercise-nutrition-and-anti-inflammatory-medication-for-cachexia-trial
#12
REVIEW
Tora S Solheim, Barry J A Laird, Trude R Balstad, Asta Bye, Guro Stene, Vickie Baracos, Florian Strasser, Gareth Griffiths, Matthew Maddocks, Marie Fallon, Stein Kaasa, Kenneth Fearon
Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a major impact on patient physical function, morbidity and mortality. Despite the consequences of cachexia, there is no licensed treatment for cachexia and no accepted standard of care. It has been argued that the multifactorial genesis of cachexia lends itself to therapeutic targeting through a multimodal treatment...
February 9, 2018: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/29439339/plasma-antioxidant-status-in-patients-with-alzheimer-s-disease-and-cognitively-intact-elderly-a-meta-analysis-of-case-control-studies
#13
Kathryn Mullan, Chris R Cardwell, Bernadette McGuinness, Jayne V Woodside, Gareth J McKay
Serum antioxidants may afford neuroprotection against Alzheimer's disease (AD) via correction of the pro-oxidative imbalance but findings reported have been inconsistent. We compared the pooled mean difference in serum levels of ten dietary antioxidants between patients with AD and cognitively intact controls from 52 studies in meta-analyses using random-effects models. Patients with AD had significantly lower plasma levels of α-carotene, β-carotene, lycopene, lutein, vitamin A, C, and E, and uric acid. No significant difference was observed for plasma levels of β-cryptoxanthin and zeaxanthin...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29436162/therapeutic-alliance-in-dietetic-practice-for-weight-loss-insights-from-health-coaching
#14
Annaliese Nagy, Anne McMahon, Linda Tapsell, Frank Deane, Danielle Arenson
AIM: The psychological construct of 'therapeutic alliance' can be used to better understand the effectiveness of consultations, particularly goal setting for weight management. We analysed audio-recorded health coaching sessions during a weight loss trial to explore relationships between therapeutic alliance and various contextual factors. METHODS: Audio recordings of 50 health coaching sessions were analysed. After assessing fidelity to the protocol, therapeutic alliance was measured using an adapted Working Alliance Inventory Observer-rated Short Version (WAI-O-S), and examined by (i) identifying relationships between contextual factors and WAI-O-S scores (Spearman's coefficients); (ii) testing the impact of preparatory exercises and body mass index on WAI-O-S scores (one-way analysis of variance and least-squared differences tests) and (iii) comparing differences in WAI-O-S scores based on relationship status, gender and follow-up session completion (independent samples t-tests)...
February 13, 2018: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29436126/aerobic-exercise-prior-to-task-specific-training-to-improve-poststroke-motor-function-a-case-series
#15
S R Valkenborghs, M M Visser, M Nilsson, R Callister, P van Vliet
BACKGROUND: Aerobic exercise can improve upper limb motor function in both healthy and stroke populations. Research in animals after stroke has shown that aerobic exercise combined with forelimb motor training improved forelimb motor function more than aerobic exercise or motor training alone. There is a lack of knowledge about this combined intervention in humans after stroke. PURPOSE: These 2 case reports describe the exploratory implementation of a combined aerobic exercise and task-specific training intervention to improve upper limb motor function in one person in subacute stroke recovery and one person in chronic stroke recovery...
February 13, 2018: Physiotherapy Research International: the Journal for Researchers and Clinicians in Physical Therapy
https://www.readbyqxmd.com/read/29433500/effects-of-local-treatment-with-and-without-sensorimotor-and-balance-exercise-in-individuals-with-neck-pain-protocol-for-a-randomized-controlled-trial
#16
Munlika Sremakaew, Gwendolen Jull, Julia Treleaven, Marco Barbero, Deborah Falla, Sureeporn Uthaikhup
BACKGROUND: Impaired cervical joint position sense and balance are associated with neck pain. Specific therapeutic exercise and manual therapy are effective for improving neck pain and functional ability but their effects on joint position sense and balance impairments remain uncertain. Changes in the joint position sense and balance may need to be addressed specifically. The primary objective is to investigate the most effective interventions to improve impaired cervical joint position sense and balance in individuals with neck pain...
February 13, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29433474/real-life-feasibility-of-home-based-pulmonary-rehabilitation-in-chemotherapy-treated-patients-with-thoracic-cancers-a-pilot-study
#17
Cecile Olivier, Jean-Marie Grosbois, Alexis B Cortot, Sophie Peres, Christophe Heron, Julie Delourme, Marianne Gierczynski, Anne Hoorelbeke, Arnaud Scherpereel, Olivier Le Rouzic
BACKGROUND: Patients with advanced lung cancer (LC) or malignant pleural mesothelioma (MPM) exhibit limitation of exercise capacities and alteration of quality of life (QoL) induced by cancer and its treatment. Few studies assessed pulmonary rehabilitation (PR) in these chemotherapy-treated patients, and none evaluated a home-based PR program. METHODS: In this prospective uncontrolled observational pilot study, patients treated by chemotherapy for LC or MPM were screened for a home-based PR program combining exercise training with global cares including therapeutic education and psychosocial management...
February 13, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29430642/should-structured-exercise-be-promoted-as-a-model-of-care-dissemination-of-the-department-of-veterans-affairs-gerofit-program
#18
Miriam C Morey, Cathy C Lee, Steven Castle, Willy M Valencia, Leslie Katzel, Jamie Giffuni, Teresa Kopp, Heather Cammarata, Michelle McDonald, Kris A Oursler, Timothy Wamsley, Chani Jain, Janet P Bettger, Megan Pearson, Kenneth M Manning, Orna Intrator, Peter Veazie, Richard Sloane, Jiejin Li, Daniel C Parker
Exercise provides a wide range of health-promoting benefits, but support is limited for clinical programs that use exercise as a means of health promotion. This stands in contrast to restorative or rehabilitative exercise, which is considered an essential medical service. We propose that there is a place for ongoing, structured wellness and health promotion programs, with exercise as the primary therapeutic focus. Such programs have long-lasting health benefits, are easily implementable, and are associated with high levels of participant satisfaction...
February 12, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29430052/-i-didn-t-pay-her-to-teach-me-how-to-fix-my-back-a-focused-ethnographic-study-exploring-chiropractors-and-chiropractic-patients-experiences-and-beliefs-regarding-exercise-adherence
#19
Peter Stilwell, Katherine Harman
Aim: To inform future research and exercise prescription for patients with chronic low back pain (CLBP), this study explored chiropractors' and chiropractic patients' experiences and beliefs regarding the barriers and facilitators to prescribed exercise adherence. Methods: A focused ethnographic approach was used involving 16 semi-structured interviews, including pilot interviews (n = 4) followed by interviews with chiropractors (n = 6) and chiropractic patients with CLBP (n = 6)...
December 2017: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/29428024/effect-of-systemic-triphenylphosphonium-on-organ-function-and-oxidative-stress
#20
Rebecca D Powell, Donna A Goodenow, A Britton Christmas, Iain H Mckillop, Susan L Evans
Conditions of systemic stress can lead to increased reactive oxygen species production, mitochondrial dysfunction, systemic inflammation, and multiorgan dysfunction. Triphenylphosphonium (TPP+) is a lipophilic cation used to target therapeutics to mitochondria. We sought to determine the effects of TPP+ on mitochondrial integrity. Male rats were anesthetized and TPP+ (5 mg/kg) or vehicle (saline) was administered intravenously 30-minutes after anesthesia initiation and intraperitoneally (20 mg/kg) 60-minutes later...
January 1, 2018: American Surgeon
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