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electrical injuries

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https://www.readbyqxmd.com/read/29149801/response-to-phillips-et-al-an-autonomic-neuroprosthesis-non-invasive-electrical-spinal-cord-stimulation-restores-autonomic-cardiovascular-function-in-individuals-with-spinal-cord-injury
#1
https://www.readbyqxmd.com/read/29148135/cadence-tracking-and-disturbance-rejection-in-functional-electrical-stimulation-cycling-for-paraplegic-subjects-a-case-study
#2
Lucas O da Fonseca, Antônio P L Bó, Juliana A Guimarães, Miguel E Gutierrez, Emerson Fachin-Martins
Functional electrical stimulation cycling has been proposed as an assistive technology with numerous health and fitness benefits for people with spinal cord injury, such as improvement in cardiovascular function, increase in muscular mass, and reduction of bone mass loss. However, some limitations, for example, lack of optimal control strategies that would delay fatigue, may still prevent this technology from achieving its full potential. In this work, we performed experiments on a person with complete spinal cord injury using a stationary tadpole trike when both cadence tracking and disturbance rejection were evaluated...
November 2017: Artificial Organs
https://www.readbyqxmd.com/read/29148129/development-of-functional-electrical-stimulation-rowing-the-rowstim-series
#3
Brian Andrews, Robin Gibbons, Garry Wheeler
Potentially, functional electrical stimulation (FES)-assisted exercise may have an important therapeutic role in reducing comorbidities associated with spinal cord injury (SCI). Here, we present an overview of these secondary life-threatening conditions, discuss the rationale behind the development of a hybrid exercise called FES rowing, and describe our experience in developing FES rowing technology. FES rowing and sculling are unique forms of adaptive rowing for those with SCI. The paralyzed leg musculature is activated by multiple channels of electrical pulses delivered via self-adhesive electrodes attached to the skin...
November 2017: Artificial Organs
https://www.readbyqxmd.com/read/29148128/step-ergometer-training-augmented-with-functional-electrical-stimulation-in-individuals-with-chronic-spinal-cord-injury-a-feasibility-study
#4
Candy Tefertiller, Don Gerber
Spinal cord injury (SCI) often results in loss of upright mobility and independence subsequently challenging rehabilitation practitioners for meaningful intervention strategies. The objective of this study was to evaluate the feasibility and potential impact on walking function of the stimulation and ergometer training protocol (STEP) in chronic SCI. Fourteen individuals with a chronic motor incomplete SCI (>1-year post injury) were enrolled in the study. The intervention consisted of a 12-week walking training program delivered three times per week from 20 up to 45 min in combination with 10 channels of FES on a step ergometer...
November 2017: Artificial Organs
https://www.readbyqxmd.com/read/29147809/application-of-actuator-driven-pulsed-water-jet-for-coronary-artery-bypass-grafting-assessment-in-a-swine-model
#5
Tomoyuki Suzuki, Shunsuke Kawamoto, Atsuhiro Nakagawa, Toshiki Endo, Teiji Tominaga, Masatoshi Akiyama, Osamu Adachi, Kiichiro Kumagai, Yoshikatsu Saiki
Actuator-driven pulsed water-jet (ADPJ) dissection is an emerging surgical method for dissecting tissue without heat and mechanical injury to vessels. We elucidated the mechanical properties of the piezo ADPJ and evaluated its usefulness and safety in coronary artery bypass grafting procedures. The relationship between the input voltage (10-100 V) and peak pressure of the pulsed water jet was evaluated. The tissue strengths of swine internal thoracic and coronary arteries and the surrounding tissues were measured to assure tissue-selective dissection...
November 16, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29141687/autologous-adipose-derived-regenerative-cell-therapy-modulates-development-of-hypertrophic-scarring-in-a-red-duroc-porcine-model
#6
Philippe Foubert, Diana Zafra, Mike Liu, Rohit Rajoria, Damian Gutierrez, Mayer Tenenhaus, John K Fraser
BACKGROUND: Effective prevention and treatment of hypertrophic scars (HTSs), a common consequence of deep-partial thickness injury, remain a significant clinical challenge. Previous studies from our group have shown that autologous adipose-derived regenerative cells (ADRCs) represent a promising approach to improve wound healing and, thereby, impact HTS development. The purpose of this study was to assess the influence of local delivery of ADRCs immediately following deep-partial thickness cutaneous injury on HTS development in the red Duroc (RD) porcine model...
November 15, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29141495/late-osteomyelitis-and-abscess-formation-of-the-ulna-after-high-voltage-electrical-injuries-review-of-literature-and-case-report
#7
Phillipp Gonser, Wenger Andrea, Oliver Lotter
No abstract text is available yet for this article.
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29138832/effect-of-moesin-phosphorylation-on-high%C3%A2-dose-sphingosine%C3%A2-1%C3%A2-phosphate%C3%A2-induced-endothelial-responses
#8
Yan Xiao, Jie Wu, Yongjun Yuan, Xiaohua Guo, Bo Chen, Qiaobing Huang
It was previously reported that low‑dose sphingosine‑1‑phosphate (S1P) enhanced endothelial barrier integrity, whereas high‑dose S1P induced endothelial monolayer hyperpermeability responses. A number of studies have revealed the underlying molecular mechanisms of the physiological‑dose of S1P on barrier‑protective effect. However, little work has been performed to determine the effect of S1P‑induced endothelial barrier responses. In the present study, the role of moesin phosphorylation in excessive S1P‑induced endothelial hyperpermeability was investigated by western blotting, fluorescence staining and transendothelial electrical resistance detection...
November 13, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29135783/beyond-the-bottom-of-the-foot-topographic-organization-of-the-foot-dorsum-in-walking
#9
Taryn Klarner, Gregory E P Pearcey, Yao Sun, Trevor S Barss, Chelsea Kaupp, Bridget Munro, Nick Frank, E Paul Zehr
INTRODUCTION: Sensory feedback from the foot dorsum during walking has only been studied globally by whole nerve stimulation. Stimulating the main nerve innervating the dorsal surface produces a functional stumble corrective response that is phase-dependently modulated. We speculated that effects evoked by activation of discrete skin regions on the foot dorsum would be topographically organized, as with the foot sole. METHODS: Nonnoxious electrical stimulation was delivered to five discrete locations on the dorsal surface of the foot during treadmill walking...
December 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29132435/vasculotide-reduces-pulmonary-hyperpermeability-in-experimental-pneumococcal-pneumonia
#10
Birgitt Gutbier, Xiaohui Jiang, Kristina Dietert, Carolin Ehrler, Jasmin Lienau, Paul Van Slyke, Harold Kim, Van C Hoang, Jason T Maynes, Daniel J Dumont, Achim D Gruber, Norbert Weissmann, Timothy J Mitchell, Norbert Suttorp, Martin Witzenrath
BACKGROUND: Community-acquired pneumonia (CAP) is a significant cause of morbidity and mortality worldwide. Despite effective antimicrobial therapy, CAP can induce pulmonary endothelial hyperpermeability resulting in life-threatening lung failure due to an exaggerated host-pathogen interaction. Treatment of acute lung injury is mainly supportive because key elements of inflammation-induced barrier disruption remain undetermined. Angiopoietin-1 (Ang-1)-mediated Tie2 activation reduces, and the Ang-1 antagonist Ang-2 increases, inflammation and endothelial permeability in sepsis...
November 13, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29132379/effects-of-somatosensory-electrical-stimulation-on-motor-function-and-cortical-oscillations
#11
Adelyn P Tu-Chan, Nikhilesh Natraj, Jason Godlove, Gary Abrams, Karunesh Ganguly
BACKGROUND: Few patients recover full hand dexterity after an acquired brain injury such as stroke. Repetitive somatosensory electrical stimulation (SES) is a promising method to promote recovery of hand function. However, studies using SES have largely focused on gross motor function; it remains unclear if it can modulate distal hand functions such as finger individuation. OBJECTIVE: The specific goal of this study was to monitor the effects of SES on individuation as well as on cortical oscillations measured using EEG, with the additional goal of identifying neurophysiological biomarkers...
November 13, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29130506/animal-models-of-acquired-epilepsy-insights-into-mechanisms-of-human-epileptogenesis
#12
Albert J Becker
In many patients who suffer from epilepsies, recurrent epileptic seizures do not start at birth but develop later in life. This holds particularly true for epilepsies with a focal seizure origin including focal cortical dysplasias (FCDs) and temporal lobe epilepsy (TLE). TLE most frequently has its seizure onset in the hippocampal formation. Hippocampal biopsies of pharmacoresistant TLE patients undergoing epilepsy surgery for seizure control most frequently reveal the damage pattern of hippocampal sclerosis, i...
November 12, 2017: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/29129689/ascorbic-acid-attenuates-endothelial-permeability-triggered-by-cell-free-hemoglobin
#13
Jamie L Kuck, Julie A Bastarache, Ciara M Shaver, Joshua P Fessel, Sergey I Dikalov, James M May, Lorraine B Ware
BACKGROUND: Increased endothelial permeability is central to shock and organ dysfunction in sepsis but therapeutics targeted to known mediators of increased endothelial permeability have been unsuccessful in patient studies. We previously reported that cell-free hemoglobin (CFH) is elevated in the majority of patients with sepsis and is associated with organ dysfunction, poor clinical outcomes and elevated markers of oxidant injury. Others have shown that Vitamin C (ascorbate) may have endothelial protective effects in sepsis...
November 9, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29127941/improving-anti-adhesion-performance-of-electrosurgical-electrode-assisted-with-ultrasonic-vibration
#14
Guang Yao, Deyuan Zhang, Daxi Geng, Xinggang Jiang
The electrosurgical electrode currently stands out as one of the most commonly used tools in minimally invasive surgery. In order to facilitate tissue cutting and accelerate wound healing, tissue adhesion to the electrosurgical electrode is considered as an extremely urgent problem to be solved. In this paper, a novel ultrasonic vibration assisted (UV-A) electrosurgical electrode is firstly proposed to overcome the problem of tissue sticking. The anti-adhesion effects were evaluated by measuring the adhesion force and the weight of tissue adhesion using the electrosurgical electrode with and without UV-A comparatively...
October 20, 2017: Ultrasonics
https://www.readbyqxmd.com/read/29119953/-the-influence-of-non-invasive-electrical-stimulation-of-the-spinal-cord-on-the-locomotor-function-of-patients-presenting-with-movement-disorders-of-central-genesis
#15
M V Balykin, R N Yakupov, V V Mashin, E Yu Kotova, Yu M Balykin, Yu P Gerasimenko
AIM: The objective of the present study was to evaluate the influence of non-invasive (transcutaneous) electrical spinal cord stimulation on the locomotor function of the patients suffering from movement disorders. PATIENTS AND METHODS: The study involved 10 patients of both sexes at the age from 32 to 70 years (including 40% of men and 60% of women) presenting with the compromised locomotor function of varying severity associated with the disturbances of cerebral blood circulation caused either by an injury to the brain and spinal cord or by stroke...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29117738/adding-high-frequency-transcutaneous-electrical-nerve-stimulation-to-the-first-phase-of-post-anterior-cruciate-ligament-reconstruction-rehabilitation-does-not-improve-pain-and-function-in-young-male-athletes-more-than-exercise-alone-a-randomized-single-blind
#16
Bijan Forogh, Hossein Aslanpour, Ehsan Fallah, Arash Babaei-Ghazani, Safoora Ebadi
PURPOSE: Knee ligamentous trauma and the following pain is one of the most prevalent athletic injuries. Transcutaneous electrical nerve stimulation is one of the conservative approaches in controlling pain which is low cost, noninvasive, and safe with low complications. Our purpose was to study whether transcutaneous electrical nerve stimulation (TENS) could help athletes perform better during the first phase of rehabilitation (0-4 weeks) after anterior cruciate ligament (ACL) reconstruction surgery and until the follow-up...
November 9, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29116946/spinal-cord-injury-by-direct-damage-during-ct-guided-c7-transforaminal-epidural-steroid-injection-a-case-report
#17
Min Cheol Chang
Cervical transforaminal epidural steroid injection (TFESI) under the guidance of computed tomography (CT) can offer great anatomical resolution and precise needle placement in the axial plane. However, some complications, including blood pressure surge, allergic reactions, vasovagal syncope, and cerebral infarct, have been reported after CT-guided cervical TFESI. We report the first case of iatrogenic spinal cord injury (SCI) during a CT-guided cervical TFESI. A 67-year-old woman, upon receiving TFESI on Lt...
November 7, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29115986/the-breaking-and-making-of-healthy-adult-human-skeletal-muscle-in-vivo
#18
Abigail L Mackey, Michael Kjaer
BACKGROUND: While muscle regeneration has been extensively studied in animal and cell culture models, in vivo myogenesis in adult human skeletal muscle has not been investigated in detail. METHODS: Using forced lengthening contractions induced by electrical stimulation, we induced myofibre injury in young healthy males. Muscle biopsies were collected from the injured leg 7 and 30 days after muscle injury and from the uninjured leg as a control. Immuno-stained single muscle fibres and muscle cross sections were studied by wide-field and confocal microscopy...
November 7, 2017: Skeletal Muscle
https://www.readbyqxmd.com/read/29115487/mir-4505-aggravates-lipopolysaccharide-induced-vascular-endothelial-injury-by-targeting-heat-shock-protein-a12b
#19
Xu Zhang, Yi Chen, Lei Wang, Qiuxiang Kang, Guifang Yu, Xiaojian Wan, Jiafeng Wang, Keming Zhu
Heat shock protein family A member 12B (HSPA12B) is a heat shock protein primarily expressed in endothelial cells. Our previous study showed that it was protective against endothelial injury induced by lipopolysaccharide (LPS). The present study was performed to investigate whether micro (mi)RNA was involved in HSPA12B expression in endothelial cells challenged by LPS. We first screened the miRNA candidates potentially related to HSPA12B by bioinformatics analysis. Then the mimics of the miRNA candidates were transfected into human umbilical vein endothelial cells (HUVECs) to investigate the miRNAs that negatively regulated HSPA12B expression...
November 2, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29110266/reparative-effects-of-poloxamer-p188-in-astrocytes-exposed-to-controlled-microcavitation
#20
Johnwesly Kanagaraj, Bo Chen, Shu Xiao, Michael Cho
Blast-induced traumatic brain injury (bTBI) is a neurological dysfunction that can result from a sudden exposure to shockwave and lead to adverse health consequences. Currently, there are no preventive measures that specifically target bTBI. Several hypotheses have been formulated to explain such injuries, including the generation of microcavitation (e.g., microbubbles) in the brain that subsequently collapses with high pressure. This study was designed to explore and elucidate potential therapeutic effects of surfactants (poloxamers P188) to partially repair the damaged brain tissue due to bTBI...
November 6, 2017: Annals of Biomedical Engineering
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