Hudaib Muhammad, Malik Hurais, Zakir Syeda Javeria, Rabbani Samra, Gnanendran Dhanushan, Syed Abdul Rehman Shah, Suri Noor Fatima, Khan Javeria, Iqbal Arham, Hussain Nowal, Abdullah Muhammad, Kumar Satesh, Khatri Mahima, Varrassi Giustino
BACKGROUND: Propofol has been the gold standard for anesthesia induction and maintenance due to its rapid onset and favorable pharmacokinetic properties. However, the search for alternative agents with improved safety and efficacy has led to the emergence of ciprofol (HSK3486), a structural analog of propofol. This systematic review and meta-analysis aim to comprehensively assess the safety and efficacy of ciprofol compared to propofol for anesthesia induction and maintenance in adult patients undergoing surgical procedures...
April 11, 2024: J Anesth Analg Crit Care