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Undertreated pain

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https://www.readbyqxmd.com/read/29678597/anxiety-but-not-depressive-like-behaviors-are-related-to-facial-hyperalgesia-in-a-model-of-trigeminal-neuropathic-pain-in-rats
#1
Eder Gambeta, Marcio Augusto Batista, Gabriel Paz Maschio, Joelle de Melo Turnes, Erika Ivanna Araya, Juliana Geremias Chichorro
Trigeminal neuralgia (TN) is a painful condition characterized by excruciating facial pain, which has a serious impact on quality of life. Depression and anxiety have been commonly associated with TN, but clinical studies report that these comorbidities are frequently underdiagnosed and undertreated in TN patients. Herein it was investigated if rats submitted to the infraorbital nerve constriction (CION), a model of trigeminal neuropathic pain, would display anxiety- and depressive-like behaviors in addition to the facial sensory changes in different time points after the nerve injury...
April 17, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29644986/evaluation-of-fatigue-in-patients-with-pancreatic-cancer-receiving-chemotherapy-treatment-a-cross-sectional-observational-study
#2
Mariacristina Di Marco, Ivan Rubbi, Agnese Baldi, Rosaria Di Lorenzo, Daniela Magnani, Valeria Cremonini, Leopoldo Sarli, Giovanna Artioli, Paola Ferri
BACKGROUND AND AIM OF THE WORK: Cancer-related fatigue (CRF) is one of the most common symptoms experienced by cancer patients (CPs) and negatively affects quality of life. Although CRF is frequently experienced, it is often underreported, underdiagnosed and undertreated. The objectives of this study were to evaluate the level of fatigue in patients with pancreatic cancer undergoing chemotherapy and to analyse its correlation with patients' demographic and clinical variables. METHODS: A cross-sectional observational study was implemented in the Oncology Day Hospital of a Northern Italian hospital...
February 27, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29642749/chronic-migraine-a-process-of-dysmodulation-and-sensitization
#3
Min Su, Shengyuan Yu
Chronic migraine is a common chronic daily headache featured by frequent headache attacks with at least 15 headache days per month, which brings great disease burden to both the sufferers and the society. Transformed from episodic migraine, the pathophysiology of chronic migraine is not fully understood, even though several risk factors have been associated with migraine progression. Recent studies have identified both structural and functional alterations in some brain regions of chronic migraine patients indicating that maladaptation of the top-down pain modulation and subsequent sensitization of trigeminal system may be important in the pathogenesis of chronic migraine...
January 2018: Molecular Pain
https://www.readbyqxmd.com/read/29623770/atypical-presentation-of-acute-coronary-syndrome-acs-a-case-report
#4
Axel Van Damme, Philippe Vanderheeren, Tine De Backer, Françine Desimpel
Case A 45-year-old man presented at the emergency department (ED) with stomach pain since eight days. The patient was not worried about his symptoms and requested only pain relief. The emergency physician requested a consult of the gastroenterologist. Clinical examination was unremarkable. However, 12-lead ECG and ischemic markers were suggestive of acute coronary syndrome (ACS) which led to admission at the cardiology department. Despite delayed presentation, the patient was still referred for urgent coronary angiogram after receiving heparin, ticagrelor and acetylsalicylic acid because of persistent pain...
April 6, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29623512/incorporating-promis-symptom-measures-into-primary-care-practice-a-randomized-clinical-trial
#5
Kurt Kroenke, Tasneem L Talib, Timothy E Stump, Jacob Kean, David A Haggstrom, Paige DeChant, Kittie R Lake, Madison Stout, Patrick O Monahan
BACKGROUND: Symptoms account for more than 400 million clinic visits annually in the USA. The SPADE symptoms (sleep, pain, anxiety, depression, and low energy/fatigue) are particularly prevalent and undertreated. OBJECTIVE: To assess the effectiveness of providing PROMIS (Patient-Reported Outcome Measure Information System) symptom scores to clinicians on symptom outcomes. DESIGN: Randomized clinical trial conducted from March 2015 through May 2016 in general internal medicine and family practice clinics in an academic healthcare system...
April 5, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29587275/efficacy-analysis-of-capsaicin-8-patch-in-neuropathic-peripheral-pain-treatment
#6
Joana Tenreiro Pinto, Frederico C Pereira, Maria C Loureiro, Ricardo Gama, Hugo L Fernandes
BACKGROUND/AIMS: Several guidelines for neuropathic pain management and various effective drugs are available; however, neuropathic pain remains undertreated. This retrospective study aimed to evaluate the efficacy of topical capsaicin 8% in peripheral neuropathic pain in a routine clinical setting. METHODS: Therapeutic efficacy was evaluated through pain intensity, using numerical pain rating scale at baseline and 7-14 days after each treatment, and using pain treatment area (PTA) assessed immediately before each treatment...
March 27, 2018: Pharmacology
https://www.readbyqxmd.com/read/29572400/improving-the-management-of-pain-from-advanced-cancer-in-the-community-study-protocol-for-a-pragmatic-multicentre-randomised-controlled-trial
#7
Matthew J Allsop, Alexandra Wright-Hughes, Kath Black, Suzanne Hartley, Marie Fletcher, Lucy E Ziegler, Bridgette M Bewick, David Meads, Nicholas D Hughes, S José Closs, Claire Hulme, Sally Taylor, Kate Flemming, Julia Hackett, John L O'Dwyer, Julia M Brown, Michael I Bennett
INTRODUCTION: For patients with advanced cancer, research shows that pain is frequent, burdensome and undertreated. Evidence-based approaches to support cancer pain management have been developed but have not been implemented within the context of the UK National Health Service. This protocol is for a pragmatic multicentre randomised controlled trial (RCT) to assess feasibility, acceptability, effectiveness and cost-effectiveness for a multicomponent intervention for pain management in patients with advanced cancer...
March 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29470472/ethnic-and-sex-related-differences-in-pain-characteristics-psychological-distress-and-pain-related-disability-in-patients-attending-a-new-zealand-teaching-hospital-pain-service
#8
Andrea Burri, David Rice, Nicola Kluger, Michal Kluger
AIM: The aim of the present observational study was to provide a description of the demographic, psychological and pain characteristics of patients attending the Waitemata Pain Services (WPS), Auckland, New Zealand. METHOD: Data were collected via a comprehensive paper-pencil questionnaire handed out to 798 consecutive new patients seen at the WPS over a four-year period. RESULTS: 32.3% attending the WPS were men and 67.7% women, with a mean age of 52...
February 23, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29432292/acute-pain-management-in-children-challenges-and-recent-improvements
#9
Catherine E Ferland, Eduardo Vega, Pablo M Ingelmo
PURPOSE OF REVIEW: The evidence regarding the efficacy of analgesics available to guide postoperative pain treatment in pediatric patients is limited. Opioid medications are very often an important component of pediatric postoperative pain treatment but have been associated with perioperative complications. We will focus on initiatives aiming to provide effective treatment minimizing the use of opioids and preventing the long-term consequences of pain. RECENT FINDINGS: Interpatient variability in postoperative pain is currently managed by applying protocols or by trial and error, thus often leading to patients being either undertreated or overtreated...
February 9, 2018: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29416865/a-week-of-pain-in-the-emergency-department
#10
Hilary Sarah Thornton, Joseph Reynolds, Timothy J Coats
Background: Pain is a common complaint in patients attending the emergency department (ED), and historically, it is under-assessed and undertreated. Previous research is heterogeneous and does not well describe pain in EDs over time. Our aim was to describe pain in a UK ED using a sample that included every adult attendance over the course of 1 week. Methods: We retrospectively reviewed every adult attendance (N = 1872) over 1 week to the ED of a large English NHS District General Hospital...
February 2018: British Journal of Pain
https://www.readbyqxmd.com/read/29318334/physiotherapy-for-pelvic-pain-and-female-sexual-dysfunction-an-untapped-resource
#11
REVIEW
Bary Berghmans
INTRODUCTION AND HYPOTHESIS: Chronic pelvic pain (CPP) in women is a complex syndrome. Pain sensation and intensity often do not correspond with the identified lesion location but are felt elsewhere, leading to muskuloskeletal and myofascial disorders and sexual dysfunction (SD). Although physical aspects are prevalent, they are often underdiagnosed and undertreated due to lack of understanding regarding its origin and distribution. Frequently, patients experience pelvic pain as psychological distress resulting in physical complaints, leading clinicians to prescribe medication or surgical intervention to correct or alleviate these symptoms, often with insufficient results...
January 9, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29278266/regional-nerve-blockade-for-early-analgesic-management-of-elderly-patients-with-hip-fracture-a-narrative-review
#12
REVIEW
A Scurrah, C T Shiner, J A Stevens, S G Faux
Elderly patients with hip fracture experience high morbidity and mortality, and are often undertreated for pain. Acute pain management in the elderly is challenging, with physiological frailty, medical comorbidities and cognitive impairment commonly compounding pain assessment and treatment. Guidelines outlining current best practice for acute pain management in the elderly now exist, but evidence suggests that practice remains variable and there continues to be scope for improvement. We conducted a narrative review of the literature to examine the challenges of acute pain management in the elderly, and to evaluate evidence for the role of regional nerve blocks for acute pain associated with hip fracture in the elderly...
December 26, 2017: Anaesthesia
https://www.readbyqxmd.com/read/29251636/ce-managing-postoperative-pain
#13
Renee C B Manworren, Debra B Gordon, Robert Montgomery
: Acute postoperative pain remains undertreated despite the dramatic increase in opioid prescribing in the United States over the past 20 years. Inadequately relieved postoperative pain may be a risk factor for persistent postoperative pain, chronic pain, and disability. In an effort to promote evidence-based strategies for optimal postoperative pain management, the American Pain Society published a new postoperative pain management guideline in 2016. Its 32 recommendations for interdisciplinary and multimodal postoperative pain management are stratified according to risks and benefits, based on varying levels of evidence...
January 2018: American Journal of Nursing
https://www.readbyqxmd.com/read/29238216/improved-health-related-quality-of-life-participation-and-autonomy-in-patients-with-treatment-resistant-chronic-pain-after-an-intensive-social-cognitive-intervention-with-the-participation-of-support-partners
#14
Peter Joseph Jongen, Rob P Ruimschotel, Y M Museler-Kreijns, Tmc Dragstra, L Duyverman, J Valkenburg-Vissers, J Cornelissen, R Lagrand, Rogier Donders, A Hartog
Despite the availability of various specific treatments, most patients with chronic pain (CP) consider their pain problem as undertreated. Recently, multiple sclerosis (MS) patients who were given an intensive 3-day social cognitive treatment with the participation of support partners experienced lasting improvements in health-related quality of life (HRQoL) and self-efficacy. In this study, a similar intervention was given to treatment-resistant CP patients with stressors, relational problems with support partner, and distress, anxiety or depression...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29224058/systematic-assessment-and-characterization-of-chronic-pain-in-multiple-sclerosis-patients
#15
Diana Ferraro, Domenico Plantone, Franca Morselli, Giulia Dallari, Anna M Simone, Francesca Vitetta, Patrizia Sola, Guido Primiano, Viviana Nociti, Matteo Pardini, Massimiliano Mirabella, Catello Vollono
Pain is one of the most disabling clinical symptoms in patients with multiple sclerosis (MS). Several studies have already assessed the prevalence of pain in MS patients, reporting variable results, probably due to methodological differences. The aim of this single-centre cross-sectional study was to define the prevalence and characteristics of chronic pain in a population of MS patients using validated tools, and to analyse these data in relation to demographic and clinical features, including disease duration and disability (EDSS and its single functional system scores)...
December 9, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29216521/the-use-of-palliative-medications-before-death-from-prostate-cancer-swedish-population-based-study-with-a-comparative-overview-of-european-data
#16
Magdalena Lycken, Linda Drevin, Hans Garmo, Pär Stattin, Jan Adolfsson, Ingela Franck Lissbrant, Lars Holmberg, Anna Bill-Axelson
BACKGROUND: Symptoms of terminal cancer have previously been reported as undertreated. The aim of this study was to assess the use of palliative medications before death from prostate cancer. METHODS: This Swedish register study included men who died from 2009 to 2012 with prostate cancer as the underlying cause of death. We assessed the proportion who collected a prescription of androgen deprivation therapy, non-steroidal anti-inflammatory drugs, paracetamol, opioids, glucocorticoids, antidepressants, anxiolytics and sedative-hypnotics and the differences in treatment related to age, time since diagnosis, educational level, close relatives and comorbidities...
January 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29189621/predictors-of-nurses-intentions-to-administer-as-needed-opioid-analgesics-for-pain-relief-to-postoperative-orthopaedic-patients-in-the-acute-care-setting
#17
Colleen Y Taylor, Jiunn-Jye Sheu, Huey-Shys Chen, Tavis Glassman, Joseph Dake
BACKGROUND: Patients undergoing orthopaedic surgery experience severe postoperative pain that is frequently undertreated. No study was found that examined the predictors of nurses' intentions to administer as needed (PRN) opioid analgesics for postoperative pain relief. PURPOSE: The purpose of this study was to determine what constructs from the Integrated Behavioral Model (IBM) can predict nurses' intentions to administer PRN opioid analgesics for pain relief to hospitalized postoperative orthopaedic patients...
November 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/29164932/development-of-the-spanish-language-houston-pain-outcome-instrument-for-spanish-speakers
#18
Jeanette McNeill, Gwen Sherwood
PURPOSE: To address reported disparities in pain management among Hispanic patients, this article reports the psychometrics of the newly developed Spanish language Houston Pain Outcome Instrument (HPOI) with postoperative Hispanic patients. METHODS: Findings from qualitative interviews conducted with 35 self-identified Hispanics in Phase 1 of the overall project were used to generate items for a new Spanish language instrument, Cuestionario de Houston Sobre el Dolor (HPOI)...
January 1, 2017: Hispanic Health Care International: the Official Journal of the National Association of Hispanic Nurses
https://www.readbyqxmd.com/read/29155288/investigation-of-the-practices-legislation-supply-chain-and-regulation-of-opioids-for-clinical-pain-management-in-southern-africa-a-multi-sectoral-cross-national-mixed-methods-study
#19
Eve Namisango, Matthew J Allsop, Richard A Powell, Stefan J Friedrichsdorf, Emmanuel Bk Luyirika, Fatia Kiyange, Edward Mukooza, Chris Ntege, Eunice Garanganga, Mavis Ntombifuthi Ginindza-Mdluli, Faith Mwangi-Powell, Lidia Justino Mondlane, Richard Harding
CONTEXT: Sub-Saharan Africa faces an increasing incidence and prevalence of life-limiting and life-threatening conditions. These conditions are associated with a significant burden of pain linked to high morbidity and disability that is poorly assessed and undertreated. Barriers to effective pain management partly relate to lack of access to opioid analgesia and challenges in their administration. OBJECTIVES: To identify country-specific and broader regional barriers to access, as well as the administration of opioids, and generate recommendations for advancing pain management in Southern Africa...
November 15, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29153920/pain-assessment-and-management-for-older-patients-with-dementia-in-hospitals-an-integrative-literature-review
#20
REVIEW
I-Pei Tsai, Sarah Yeun-Sim Jeong, Sharyn Hunter
Previous studies have suggested that pain in older people with dementia is often underestimated and undertreated in acute hospitals. Undermanaged pain negatively affects a person's recovery and prolongs hospital stays. However, the issues related to pain assessment and management by nurses for this group have not been fully understood. (1) To synthesize evidence about pain assessment and management for older people with dementia in hospital settings, and (2) to discuss implications for nurses and their practice...
November 16, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
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