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https://www.readbyqxmd.com/read/27900095/intravenous-leiomyomatosis-with-right-atrium-extension-in-two-patients-a-case-report
#1
Lianxue Zhang, Yang Duan, Fulin Song, Junrui Xiao, Benqiang Yang
Intravenous leiomyomatosis (IVL) is a rare benign tumor of the uterus mesoderm, which can spread via the vein, from the micro-vein to the inferior vena cava, and even to the right atrium. IVL was first described this disease in 1896 and the first presented case of IVL with right atrium extension in the autopsy was described in 1907. On rare occasions, the tumors may extend into the regional and systemic veins, thus reaching the heart. This may subsequently cause intracardiac leiomyomatosis (ICL), which may lead to congestive heart failure and on occasion, sudden fatalities...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27863160/primary-b-cell-lymphoma-of-the-uterine-cervix-presentation-in-pap-test-slide-and-cervical-biopsy
#2
Guang Yang, Jeremy Deisch, Margaret Tavares, Qin Haixia, Camilla Cobb, Anwar S Raza
This case involved a 69-year-old female who presented with irritative urinary voiding. Imaging studies showed an 18-cm uterine mass centering on the cervix and extending into the bladder. The Pap test slide demonstrated necrotic background and degenerative changes in single and grouped atypical "small round blue cells" with high nuclear/cytoplasm ratio, scant cytoplasm, and hyperchromatic focally cleaved nuclei with occasional nuclear membrane "snout projections." Cervical biopsies showed similar findings. The tumor cells were positive for CD45, CD20, and PAX-5, and negative with epithelial, neuroendocrine, and muscle markers...
November 8, 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27859319/uterine-angioleiomyoma-in-an-african-green-monkey-chlorocebus-aethiops-sabaeus
#3
Matthew John Valentine, Amy Beierschmitt, Josepha DeLay, John Joseph Callanan
BACKGROUND: A uterine neoplasm was observed, as an incidental finding, during post-mortem examination of a 26-year-old female multiparous African green monkey (Chlorocebus aethiops sabaeus). The intramural, expansile, 2 to 3 cm well-demarcated, dark-red, nodular neoplasm was located on the anterior uterine body (corpus) wall. METHODS: The mass was examined by light microscopy and by immunohistochemistry. RESULTS: The mass was confirmed as a cavernous uterine angioleiomyoma (syn...
November 8, 2016: Journal of Medical Primatology
https://www.readbyqxmd.com/read/27857930/neural-axis-metastasis-from-metachronous-pulmonary-basaloid-carcinoma-developed-after-chemotherapy-radiation-therapy-of-uterine-cervical-carcinoma
#4
Myeong Jin Oh, Je Hoon Jeong, Soo Bin Im, Jeong Ja Kwak, Kye-Hyun Nam
Multiple primary or secondary malignancies after anticancer therapy were recently reported to be increasing in frequency. The authors describe a case of metachronous metastatic pulmonary basaloid carcinoma to the central nervous system that was discovered after chemotherapy and radiation therapy for cervical uterine carcinoma. Two different types of cancer developed within some interval. There's the possibility that a secondary pulmonary neoplasm developed after the chemotherapy and radiotherapy conducted as cervical cancer treatment...
October 2016: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/27846844/a-rare-case-with-synchronous-gastric-gastrointestinal-stromal-tumor-pancreatic-neuroendocrine-tumor-and-uterine-leiomyoma
#5
Elena Arabadzhieva, Atanas Yonkov, Sasho Bonev, Dimitar Bulanov, Ivanka Taneva, Alexandrina Vlahova, Tihomir Dikov, Violeta Dimitrova
BACKGROUND: Although gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, they comprise less than 1% of all gastrointestinal tumors. Neuroendocrine tumors (NET) of the gastro-enteropancreatic system are also rare, representing about 2% of all gastrointestinal neoplasms. Pancreatic localization of NET is extremely uncommon-these tumors are only 1-5% of all pancreatic cancers. CASE PRESENTATION: We describe an unusual case with triple tumor localization-a gastric tumor, a formation in the pancreas, which involves the retroperitoneal space, and a uterine leiomyoma...
November 15, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27826698/mr-imaging-of-atypical-fibroids
#6
Candice Bolan, Melanie P Caserta
Leiomyomas are the most common neoplasm found in the uterus and can present with a variety of symptoms or be entirely asymptomatic. Most often, the characteristic imaging appearance of leiomyoma does not pose a diagnostic dilemma. However, leiomyomas can demonstrate atypical imaging features that may be confusing. It is essential for the radiologist to be aware of both the typical and atypical findings to better assist the referring clinician with diagnosis and management decisions. Additionally, as uterine-sparing treatment alternatives with locoregional therapies become more popular, it is important to be aware of pre- and post-procedural imaging questions that may be encountered...
November 8, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27826577/a-rare-presentation-of-acute-heart-failure-secondary-to-aggressive-uterine-leiomyosarcoma-metastatic-to-the-myocardium-initially-diagnosed-as-hypertrophic-obstructive-cardiomyopathy
#7
Michael Karass, Pratik Mondal, Mohammad Alkayem, Amole Ojo, Wilbert S Aronow, Carmelo Puccio
Uterine sarcoma is the cause of 3-9% of all uterine malignant neoplasms and has a 2-fold higher incidence in black women as compared to white women. Cellular atypia and abundant mitoses (≥10 per 10 high power fields) as seen in this patient are associated with an increased risk for metastases. Metastases to the heart are infrequently reported with a handful of cases in the literature. We present a case of a 51-year-old woman with aggressively metastatic uterine leiomyosarcoma causing acute heart failure 4 months after initial presentation...
October 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27821836/effects-of-combined-general-epidural-anesthesia-on-hemodynamics-respiratory-function-and-stress-hormone-levels-in-patients-with-ovarian-neoplasm-undergoing-laparoscopy
#8
Qiang Xu, Hao Zhang, Yan-Mei Zhu, Nian-Jun Shi
BACKGROUND The aim of this study was to evaluate the influence of combined general/epidural anesthesia (GEA) on hemodynamics, respiratory function and stress hormone levels in patients with ovarian neoplasm undergoing laparoscopy. MATERIAL AND METHODS A total of 177 patients with ovarian neoplasm (screened by inclusion/exclusion criteria) receiving laparoscopy were divided into groups G (general anesthesia alone), L1.0 (GEA with 1.0% lidocaine), and L1.5 (GEA with 1.5% lidocaine). Hemodynamics, respiratory parameters and stress hormone levels in the 3 groups were recorded and analyzed...
November 8, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27791010/mutational-landscape-of-uterine-and-ovarian-carcinosarcomas-implicates-histone-genes-in-epithelial-mesenchymal-transition
#9
Siming Zhao, Stefania Bellone, Salvatore Lopez, Durga Thakral, Carlton Schwab, Diana P English, Jonathan Black, Emiliano Cocco, Jungmin Choi, Luca Zammataro, Federica Predolini, Elena Bonazzoli, Mark Bi, Natalia Buza, Pei Hui, Serena Wong, Maysa Abu-Khalaf, Antonella Ravaggi, Eliana Bignotti, Elisabetta Bandiera, Chiara Romani, Paola Todeschini, Renata Tassi, Laura Zanotti, Franco Odicino, Sergio Pecorelli, Carla Donzelli, Laura Ardighieri, Fabio Facchetti, Marcella Falchetti, Dan-Arin Silasi, Elena Ratner, Masoud Azodi, Peter E Schwartz, Shrikant Mane, Roberto Angioli, Corrado Terranova, Charles Matthew Quick, Babak Edraki, Kaya Bilgüvar, Moses Lee, Murim Choi, Amy L Stiegler, Titus J Boggon, Joseph Schlessinger, Richard P Lifton, Alessandro D Santin
Carcinosarcomas (CSs) of the uterus and ovary are highly aggressive neoplasms containing both carcinomatous and sarcomatous elements. We analyzed the mutational landscape of 68 uterine and ovarian CSs by whole-exome sequencing. We also performed multiregion whole-exome sequencing comprising two carcinoma and sarcoma samples from six tumors to resolve their evolutionary histories. The results demonstrated that carcinomatous and sarcomatous elements derive from a common precursor having mutations typical of carcinomas...
October 25, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27790528/benign-pulmonary-metastasizing-leiomyoma-of-the-uterus
#10
Nurettin Aka, Reyyan Iscan, Gültekin Köse, Isik Kaban
Benign Metastasizing Leiomyoma (BML) is a rare disease which represents with multiple leiomyomatous lesions in many tissues and organs especially in lungs. These patients have been operated for leiomyoma of the uterus. Here we report a case of a 41-year-old woman who was evaluated in a thoracic surgery hospital for dyspnea and bilateral nodules in chest roentgenogram. She had no history of neoplasm, only myomectomy history of uterine leiomyoma 10 years ago. Biopsy and histopathological examination were consistent with pulmonary leiomyoma...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27757274/effects-of-herbal-medicine-on-human-uterine-tumor-bearing-nude-mice
#11
Mi Hyang Ohh, Seong Jin Kim, Jong Kwon Han, Sok Cheon Pak, Kew-Mahn Chee
AIM: Uterine leiomyomas are the most common benign uterine neoplasms associated with significant morbidity. Herbal formulas capable of restoring yin-yang balance by dispersing blood stasis may be useful for managing fibroid symptoms. MATERIALS AND METHODS: In this study, the antitumor properties of three herbs viz., Trogopterus xanthipes Milen-Edwards, Paeonia lactiflora Pallas, and Ulmus davidiana Planch were evaluated in nude mice injected intravenously with human malignant myomas...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27738815/-new-features-in-the-2014-who-classification-of-uterine-neoplasms
#12
S F Lax
The 2014 World Health Organization (WHO) classification of uterine tumors revealed simplification of the classification by fusion of several entities and the introduction of novel entities. Among the multitude of alterations, the following are named: a simplified classification for precursor lesions of endometrial carcinoma now distinguishes between hyperplasia without atypia and atypical hyperplasia, the latter also known as endometrioid intraepithelial neoplasia (EIN). For endometrial carcinoma a differentiation is made between type 1 (endometrioid carcinoma with variants and mucinous carcinoma) and type 2 (serous and clear cell carcinoma)...
October 13, 2016: Der Pathologe
https://www.readbyqxmd.com/read/27738813/-endometritis-rare-disease-with-clinical-importance
#13
S F Lax
Endometritis is nowadays rare in developed countries and typically shows a subclinical or mild course; therefore, there are probably more cases of endometritis than diagnosed but they lack clinical relevance. In the fertile period of life it can be the reason for vaginal bleeding and infertility. The most common causes for non-specific endometritis are residual placental tissue after abortion or childbirth, intrauterine interventions, lesions within the uterine cavity, such as endometrial polyps, endometrial hyperplasia and neoplasms, intrauterine devices (IUD) and cervical stenosis...
October 13, 2016: Der Pathologe
https://www.readbyqxmd.com/read/27721643/an-unusual-case-of-cervical-fibroid-masquerading-as-ovarian-tumor
#14
Neeru Goel, Shikha Seth
Uterine fibroids are the most common uterine neoplasm of uterus and the female pelvis and the most common indication for hysterectomy worldwide. When the fibroid is large and fills the whole pelvis or is pedunculated, it becomes difficult to differentiate from ovarian mass clinically. Cervical fibroids pose enormous surgical difficulty by virtue of their relative inaccessibility and proximity to the anterior bladder, posterior rectum, and distorting the normal anatomical relationship of pelvic structures. A cervical fibroid especially with degenerative changes mimics an ovarian tumor and poses a clinical dilemma...
July 2016: Journal of Mid-life Health
https://www.readbyqxmd.com/read/27703679/prognostic-impact-of-primary-tumor-suvmax-on-preoperative-18-f-fluoro-2-deoxy-d-glucose-positron-emission-tomography-and-computed-tomography-in-endometrial-cancer-and-uterine-carcinosarcoma
#15
Tamaki Yahata, Shigetaka Yagi, Yasushi Mabuchi, Yuko Tanizaki, Aya Kobayashi, Madoka Yamamoto, Mika Mizoguchi, Sakiko Nanjo, Michihisa Shiro, Nami Ota, Sawako Minami, Masaki Terada, Kazuhiko Ino
The objective of the present study was to investigate the usefulness of the maximum standardized uptake value (SUVmax) of the primary tumor on preoperative (18)F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography and computed tomography (PET/CT) as a prognostic indicator in patients with endometrial neoplasms. A total of 75 patients with endometrial cancer or uterine carcinosarcoma who underwent surgical treatment were included in the present study. All patients underwent preoperative PET/CT, and the correlation between the SUVmax of the primary tumor and clinical outcomes was analyzed...
October 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27701078/spontaneous-reproductive-pathology-in-female-guinea-pigs
#16
Tamara Veiga-Parga, Krista M D La Perle, Shelley J Newman
Reproductive pathology of domestic guinea pigs is underreported to date. To provide a comprehensive review of uterine disease in guinea pigs, we performed a retrospective study of the pathology archives of the University of Tennessee, College of Veterinary Medicine. By histology, 13 of 37 uterine lesions in 23 animals were neoplastic; the other 24 nonneoplastic lesions included cystic endometrial hyperplasia (16 of 24), endometrial hemorrhage (3 of 24), pyometra (2 of 24), polyp (2 of 24), and mucometra (1 of 24)...
November 2016: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/27669672/poorly-differentiated-squamous-cell-carcinoma-of-the-cervix-with-sarcomatoid-differentiation-report-of-a-case-with-cytohistological-correlation
#17
Israh Akhtar, Rhyne Flowers, Theresa Nuttli, Vikas Nath, Mithra Baliga
Sarcomatoid squamous cell carcinoma (SSCC) of the uterine cervix is a rare malignancy with uncertain pathogenesis and aggressive clinical behavior. The diagnosis of this tumor poses a challenge to the cytopathologist since accurate diagnosis is based on identification of two malignant components, that is, epithelial and sarcomatoid. Most cases usually lack the sarcomatoid component on Papanicolaou test (Pap test). Therefore, a poorly differentiated carcinoma or malignant neoplasm is the most often rendered diagnosis...
September 27, 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27632930/laparoscopic-management-of-huge-myoma-nascendi
#18
Nuri Peker, Savas Gundogan, Fatih Sendag
To present the feasibility of laparoscopic management of huge myoma nascendi DESIGN: Step by step explanation of the surgery using video SETTING: Uterine fibroids are the most common benign neoplasm of the female reproductive tract with the estimated incidence of 25-30% at reproductive age. Patients generally have no symptoms however patients those have symptoms such as severe pelvic pain, heavy uterine bleeding or infertility may undergo surgery. The traditional management is surgery however uterine artery embolization, hormonal therapy using GnRH (Gonadotropin-Releasing Hormone) agonists or SERM (Selective Estrogen Receptor Modulator) should be preferred as the medical approach...
September 12, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27632929/laparoscopic-management-of-huge-cervical-myoma
#19
Nuri Peker, Savaş Gundogan, Fatih Şendağ
To present the feasibility of laparoscopic management of huge cervical myoma DESIGN: Step by step explanation of the surgery using video SETTING: Uterine fibroids are the most common benign neoplasm of the female reproductive tract with the estimated incidence of 25-30% at reproductive age. Patients generally have no symptoms however patients those have symptoms such as severe pelvic pain, heavy uterine bleeding or infertility may undergo surgery. The traditional management is surgery however uterine artery embolization, hormonal therapy using GnRH (Gonadotropin-Releasing Hormone) agonists or SERM (Selective Estrogen Receptor Modulator) should be preferred as the medical approach...
September 12, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27631522/yolk-sac-tumor-in-extragonadal-pelvic-sites-still-a-diagnostic-challenge
#20
Sanjita Ravishankar, Anais Malpica, Preetha Ramalingam, Elizabeth D Euscher
We present the clinicopathologic features of 15 cases of extragonadal yolk sac tumor (EGYST) detected in female patients and reviewed at our institution from 1988 to 2016. We recorded: patient age, clinical presentation, tumor location, FIGO stage (where applicable), histologic patterns including presence/absence of Schiller-Duval bodies, other germ cell or somatic components, immunoperoxidase results, treatment, and outcome. Patients' ages ranged from 17 to 87 (median, 62) years and presentation included: abnormal uterine bleeding, 12; hematuria, 1; labial mass, 1; abdominal pain, 1...
September 14, 2016: American Journal of Surgical Pathology
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