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https://www.readbyqxmd.com/read/29781774/a-perfect-storm-challenges-encountered-by-family-caregivers-of-persons-with-alzheimer-s-disease-during-natural-disasters
#1
Allison Gibson, Jessica Walsh, Lisa M Brown
Since Hurricane Katrina there has been a movement across the U.S. to examine best practice for disaster response within the aging population. However, little is known about the experience of natural disasters from the perspective of family caregivers of persons with Alzheimer's disease and related dementia (ADRD). In this exploratory, qualitative study, family caregivers (n=27) were interviewed about their experience with the historic 2015 South Carolina flood. By using thematic analysis, themes were identified to better understand what unique challenges caregivers of person with ADRD experienced...
May 21, 2018: Journal of Gerontological Social Work
https://www.readbyqxmd.com/read/29780597/outcomes-and-prognostic-factors-of-fecal-microbiota-transplantation-in-patients-with-slow-transit-constipation-results-from-a-prospective-study-with-long-term-follow-up
#2
Chao Ding, Wenting Fan, Lili Gu, Hongliang Tian, Xiaolong Ge, Jianfeng Gong, Yongzhan Nie, Ning Li
Background and aim: Gut microbiota may contribute to regulate colonic motility, which is involved in the etiology of constipation. Fecal microbiota transplantation (FMT) has been demonstrated to restore intestinal homeostasis. The aim of this study was to evaluate the clinical outcomes and prognostic factors of FMT for the treatment of slow transit constipation (STC). Methods: Fifty-two patients with STC received standardized FMT and were followed up for 6 months...
May 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/29779725/anterior-subtemporal-approach-for-severe-upper-pontine-hematomas-a-report-of-28-surgically-treated-cases
#3
Hong-Tian Zhang, Li-Hua Chen, Miao-Chun Bai, Ru-Xiang Xu
The efficacy and safety of surgery for patients with primary pontine hemorrhage (PPH) remain debatable. Twenty-eight consecutive patients with huge upper PPH were included in this study. They underwent surgical management through a subtemporal approach between January 2009 and October 2013. We analyzed clinical and radiological parameters to assess the patient outcomes. The near-complete (>90%) evacuation rate was 67.9%, and there was no surgery-related death. The overall survival rate at 3 months was 64...
May 17, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29778897/measurement-of-ambient-dose-equivalent-rates-by-walk-survey-around-fukushima-dai-ichi-nuclear-power-plant-using-kurama-ii-until-2016
#4
Masaki Andoh, Hideaki Yamamoto, Takashi Kanno, Kimiaki Saito
Ambient dose equivalent rates in various environments related to human lives were measured by walk surveys using the KURAMA-II systems from 2013 to 2016 within an 80-km radius of the Fukushima Dai-ichi Nuclear Power Plant. The dose rate of the locations where the walk survey was performed decreased to about 38% of its initial value in the 42 months from June 2013 to the December 2016, which was beyond that attributable to the physical decay of radiocaesium. The ecological half-life of the slow decreasing component was evaluated to be 4...
May 17, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29776868/hemorrhagic-cystitis-after-hematopoietic-stem-cell-transplantation-a-challenge-for-the-pediatric-urologist
#5
REVIEW
Romy Gander, Marino Asensio, Gabriela Guillén, Gloria Fatou Royo, Andrea Bolaños, Mercedes Pérez, Cristina Diaz-De-Heredia, Maribel Benitez, Manuel López
OBJECTIVE: Hemorrhagic cystitis (HC) is a serious event that can occur after hematopoietic stem cell transplantation (HSCT). Treatment goals are primarily to preserve life, and then the functionality of the bladder. There is no standard therapeutic approach for HC. Described treatment options provide low success rates and are related to potential life-threatening side effects. The aim of this study was to describe our experience in treatment of HC following HSCT. PATIENTS AND METHODS: This was a retrospective study of patients with HC treated at our institution between January 2010 and October 2016...
April 20, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29776718/high-urinary-ferritin-reflects-myoglobin-iron-evacuation-in-dmd-patients
#6
Jérémy Rouillon, Thibaud Lefebvre, Jérôme Denard, Vincent Puy, Raed Daher, Jérôme Ausseil, Aleksandar Zocevic, Paul Fogel, Katell Peoc'h, Brenda Wong, Laurent Servais, Thomas Voit, Herve Puy, Zoubida Karim, Fedor Svinartchouk
Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in the dystrophin gene leading to the absence of the normal dystrophin protein. The efforts of many laboratories brought new treatments of DMD to the reality, but ongoing and forthcoming clinical trials suffer from absence of valuable biomarkers permitting to follow the outcome of the treatment day by day and to adjust the treatment if needed. In the present study the levels of 128 urinary proteins including growth factors, cytokines and chemokines were compared in urine of DMD patients and age related control subjects by antibody array approach...
March 20, 2018: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/29776087/effect-of-form-of-obstacle-on-speed-of-crowd-evacuation
#7
Ryosuke Yano
This paper investigates the effect of the form of an obstacle on the time that a crowd takes to evacuate a room, using a toy model. Pedestrians are modeled as active soft matter moving toward a point with intended velocities. An obstacle is placed in front of the exit, and it has one of four shapes: a cylindrical column, a triangular prism, a quadratic prism, or a diamond prism. Numerical results indicate that the evacuation-completion time depends on the shape of the obstacle. Obstacles with a circular cylinder (C...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29774192/efficacy-of-the-all-in-one-therapeutic-strategy-for-severe-traumatic-brain-injury-preliminary-outcome-and-limitation
#8
Young-Soo Park, Yohei Kogeichi, Yoichi Shida, Hiroyuki Nakase
Objective: Despite recent advances in medicine, no significant improvement has been achieved in therapeutic outcomes for severe traumatic brain injury (TBI). In the treatment of severe multiple traumas, accurate judgment and prompt action corresponding to rapid pathophysiological changes are required. Therefore, we developed the "All-in-One" therapeutic strategy for severe TBI. In this report, we present the therapeutic concept and discuss its efficacy and limitations. Methods: From April 2007 to December 2015, 439 patients diagnosed as having traumatic intracranial injuries were treated at our institution...
April 2018: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29771120/effects-of-se-incorporation-in-la-5-ti-2-cus-5-o-7-by-annealing-on-physical-properties-and-photocatalytic-h-2-evolution-activity
#9
Swarnava Nandy, Takashi Hisatomi, Song Sun, Masao Katayama, Tsutomu Minegishi, Kazunari Domen
Oxysulfoselenide semiconductor photocatalysts absorb light at longer wavelengths than the corresponding oxysulfides. However, the synthesis of oxysulfoselenides is challenging due to excessive particle growth and the limited availability of metal selenide precursors. In this study, a La5 Ti2 CuS5 O7 (LTCSO) oxysulfide was annealed with Se powder in sealed, evacuated quartz tubes to obtain LTCSO:Se photocatalysts, and the properties of these materials were investigated. Se was found to be incorporated into the LTCSO upon heating at 973 K or higher, and the Se/(S + Se) ratio was increased to a maximum of 0...
May 17, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29767779/survival-outcomes-after-intracranial-hemorrhage-in-liver-disease
#10
Carlito Lagman, Daniel T Nagasawa, Daniel Azzam, John P Sheppard, Cheng Hao Jacky Chen, Vera Ong, Thien Nguyen, Giyarpuram N Prashant, Tianyi Niu, Alexander M Tucker, Won Kim, Fady M Kaldas, Nader Pouratian, Ronald W Busuttil, Isaac Yang
BACKGROUND: Survival outcomes for patients with liver disease who suffer an intracranial hemorrhage (ICH) have not been thoroughly investigated. OBJECTIVE: To understand survival outcomes for 3 groups: (1) patients with an admission diagnosis of liver disease (end-stage liver disease [ESLD] or non-ESLD) who developed an ICH in the hospital, (2) patients with ESLD who undergo either operative vs nonoperative management, and (3) patients with ESLD on the liver transplant waitlist who developed an ICH in the hospital...
May 15, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29762769/scandinavian-multicenter-acute-subdural-hematoma-smash-study-study-protocol-for-a-multinational-population-based-consecutive-cohort
#11
(no author information available yet)
BACKGROUND: Traumatic acute subdural hematomas (ASDHs) are associated with high rate of morbidity and mortality, especially in elderly individuals. However, recent reports indicate that the morbidity and mortality rates might have improved. OBJECTIVE: To evaluate postoperative (30-d) mortality in younger vs elderly (≥70 yr) patients with ASDH. Comparing younger and elderly patients, the secondary objectives are morbidity patterns of care and 6 mo outcome according to Glasgow outcome scale (GOS)...
May 14, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29762758/in-situ-left-azygous-anterior-cerebral-artery-to-right-pericallosal-artery-bypass-for-treatment-of-a-giant-right-a1-2-aneurysm-2-dimensional-operative-video
#12
Gary Rajah, Mark Hoeprich, Sandra Narayanan, Murali Guthikonda, Sandeep Mittal
Here we present a 46-yr-old man with recurrent syncopal episodes thought to be of cardiac origin. He was eventually found to harbor a giant, partially thrombosed, saccular aneurysm arising from the A1/A2 segment of the right anterior cerebral artery with foramen of Monro obstruction and a trapped left-sided ventricular system. An azygous left A2 artery segment supplied both callosomarginal arteries. We performed an in situ side-to-side anastomosis between the distal left azygous anterior cerebral artery and the right pericallosal artery, which was previously supplied by the right A1...
May 12, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29760959/molecular-epidemiology-of-multidrug-resistant-bacteria-isolated-from-libyan-and-syrian-patients-with-war-injuries-in-two-bundeswehr-hospitals-in-germany
#13
Hagen Frickmann, Thomas Köller, Ralf Matthias Hagen, Klaus-Peter Ebert, Martin Müller, Werner Wenzel, Renate Gatzer, Ulrich Schotte, Alfred Binder, Romy Skusa, Philipp Warnke, Andreas Podbielski, Christian Rückert, Bernd Kreikemeyer
Introduction: We assessed the molecular epidemiology of multidrug-resistant bacteria colonizing or infecting war-injured patients from Libya and Syria who were treated at the Bundeswehr hospitals Hamburg and Westerstede, Germany. Methods: Enterobacteriaceae and Gram-negative rod-shaped nonfermentative bacteria with resistance against third-generation methoxyimino cephalosporins or carbapenems as well as methicillin-resistant Staphylococcus aureus (MRSA) from war-injured patients from Libya and Syria were assessed by molecular typing, i...
April 2018: European Journal of Microbiology & Immunology
https://www.readbyqxmd.com/read/29760311/postoperative-subdural-air-collection-is-a-risk-factor-for-chronic-subdural-hematoma-after-surgical-clipping-of-cerebral-aneurysms
#14
Shuhei Kawabata, Shoichi Tani, Hirotoshi Imamura, Hidemitsu Adachi, Nobuyuki Sakai
The precise mechanism of the development of chronic subdural hematoma (CSDH) as a postoperative complication after aneurysmal clipping remains unclear. The purpose of this study was to identify the independent risk factors for CSDH after craniotomy for aneurysmal clipping and to elucidate the relationship between CSDH and subdural air (SDA) collection immediately after surgery. The medical records and radiologic data of 344 patients who underwent surgical clipping of unruptured aneurysms from July 2010 to July 2016 were retrospectively evaluated...
May 11, 2018: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/29758369/intraoperative-active-bleeding-in-endoscopic-surgery-for-spontaneous-intracerebral-hemorrhage-is-predicted-by-the-spot-sign
#15
Koichi Miki, Kenji Yagi, Masani Nonaka, Mitsutoshi Iwaasa, Hiroshi Abe, Takashi Morishita, Hisatomi Arima, Tooru Inoue
BACKGROUND: Endoscopic evacuation of hematoma (EEH) has recently been applied to treat patients with spontaneous intracerebral hemorrhage (sICH). Intraoperative active bleeding (IAB), which is occasionally observed in EEH, might lead to greater blood loss, further brain damage, and more postoperative recurrent hemorrhage. However, no definite predictor of IAB has been established. Because the spot sign is associated with other hemorrhagic complications, we aimed to evaluate whether it predicts IAB...
May 11, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29756530/the-occurrence-of-spontaneous-cortical-spreading-depression-is-increased-by-blood-constituents-and-impairs-neurological-recovery-after-subdural-hematoma-in-rats
#16
Harald Krenzlin, Daniel Jussen, Michaela Maria Plath, Stephan Tretzel, Tobias Kraemer, Oliver Kempski, Beat Alessandri
Acute subdural haemorrhage (ASDH) is common and associated with severe morbidity and mortality. To date, the role of spontaneous cortical spreading depression (sCSD) in exaggerating secondary injury after ASDH, is poorly understood. The present study contains two experimental groups: First, we investigated and characterized the occurrence of sCSD after subdural blood infusion (300 µl) via tissue impedance (IMP) measurement in a rat model. Second, we compared the occurrence and influence of sCSD on lesion growth and neurological deficit in the presence and absence of whole blood constituents...
May 14, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29755898/an-unusual-presentation-of-kikuchi-fujimoto-disease-with-recurrent-subdural-effusion
#17
Sara Shahid, Syed H Alam, Indira Hadley
A 24-year-old man complained of a right temporal headache for four weeks. The patient denied any trauma or previous anticoagulation use. He also reported tender right facial swelling. His physical exam was unrevealing except for right cranial nerve (CN) VI palsy, right parotid enlargement, and cervical adenopathy. Laboratory findings were significant for mild leukopenia at 3300 cells/uL. The computed tomography (CT) scan obtained showed a chronic left subdural effusion with a 4 mm midline shift and confirmed right parotid enlargement and cervical lymphadenopathy...
March 10, 2018: Curēus
https://www.readbyqxmd.com/read/29751788/determination-of-medical-abortion-success-by-women-and-community-health-volunteers-in-nepal-using-a-symptom-checklist
#18
Kathryn L Andersen, Mary Fjerstad, Indira Basnett, Shailes Neupane, Valerie Acre, Sharad Sharma, Emily Jackson
BACKGROUND: We sought to determine if female community health volunteers (FCHVs) and literate women in Nepal can accurately determine success of medical abortion (MA) using a symptom checklist, compared to experienced abortion providers. METHODS: Women undergoing MA, and FCHVs, independently assessed the success of each woman's abortion using an 8-question symptom checklist. Any answers in a red-shaded box indicated that the abortion may not have been successful...
May 11, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29751185/obstructive-hydrocephalus-in-a-newborn-due-to-cerebral-atrium-diverticulum-formation-complete-resolution-after-subdural-hematoma-evacuation
#19
Rodolfo Maduri, Viviana Aureli, Edoardo Viaroli, Mattia Rizzi, Lorenzo Giammattei, Roy Thomas Daniel, Mahmoud Messerer
No abstract text is available yet for this article.
May 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29749940/safety-and-efficacy-of-transvenous-lead-extraction-utilizing-the-evolution-mechanical-lead-extraction-system-a-single-center-experience
#20
Saumya Sharma, Ijeoma A Ekeruo, Nikita P Nand, Ajay Sundara Raman, Xu Zhang, Sunil K Reddy, Ramesh Hariharan
OBJECTIVES: The goal of this study is to assess the safety and efficacy of mechanical lead extraction utilizing the Evolution system. BACKGROUND: Compared with other techniques commonly used for lead extraction, data regarding the safety and efficacy of mechanical lead extraction using the Evolution system is limited and needs further evaluation. METHODS: Between June 1, 2009 and September 30, 2016, we retrospectively analyzed 400 consecutive patients who exclusively underwent mechanical lead extraction utilizing the Evolution system...
February 2018: JACC. Clinical Electrophysiology
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