Femke K Aarsen, Philippe F Paquier, Willem-Frans Arts, Marie-Lise Van Veelen, Erna Michiels, Maarten Lequin, Coriene E Catsman-Berrevoets
PURPOSE To prospectively study cognitive deficits and predictors 3 years after diagnosis in a large series of pediatric patients treated for pilocytic astrocytoma (PA). PATIENTS AND METHODS Sixty-one of 67 children were grouped according to infratentorial, supratentorial midline, and supratentorial hemispheric site. Intelligence, memory, attention, language, visual-spatial, and executive functions were assessed. Included predictors were sex, age, relapse, diagnosis-assessment interval, hydrocephalus, kind of treatment, and tumor variables...
July 20, 2009: Journal of Clinical Oncology