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Peripheral blood gene expression in transient ischemic attack , carotid stenosis

S Ferronato, M G Lira, S Olivato, A Scuro, G F Veraldi, M G Romanelli, C Patuzzo, G Malerba, P F Pignatti, S Mazzucco
OBJECTIVES: An inflammatory process following stroke in human brains and systemic inflammatory responses after stroke in humans have been reported by numerous investigators. The aim of the study was to investigate if genes involved in the cyclooxygenase 2 (COX-2) pathway are upregulated at peripheral level in patients after transient ischaemic attack (TIA) and stroke. DESIGN OF STUDY: Blood samples were obtained from two groups of patients undergoing carotid endarterectomy...
March 2011: European Journal of Vascular and Endovascular Surgery
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