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https://www.readbyqxmd.com/read/28225155/remotely-supervised-transcranial-direct-current-stimulation-increases-the-benefit-of-at-home-cognitive-training-in-multiple-sclerosis
#1
Leigh Charvet, Michael Shaw, Bryan Dobbs, Ariana Frontario, Kathleen Sherman, Marom Bikson, Abhishek Datta, Lauren Krupp, Esmail Zeinapour, Margaret Kasschau
OBJECTIVE: To explore the efficacy of remotely-supervised transcranial direct current stimulation (RS-tDCS) paired with cognitive training (CT) exercise in participants with multiple sclerosis (MS). METHODS: In a feasibility study of RS-tDCS in MS, participants completed ten sessions of tDCS paired with CT (1.5 mA × 20 min, dorsolateral prefrontal cortex montage). RS-tDCS participants were compared to a control group of adults with MS who underwent ten 20-min CT sessions through the same remotely supervised procedures...
February 22, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28223806/efficacy-of-a-short-cognitive-training-program-in-patients-with-multiple-sclerosis
#2
María Yaiza Pérez-Martín, Montserrat González-Platas, Pablo Eguía-Del Río, Cristina Croissier-Elías, Alejandro Jiménez Sosa
BACKGROUND: Cognitive impairment is a common feature in multiple sclerosis (MS) and may have a substantial impact on quality of life. Evidence about the effectiveness of neuropsychological rehabilitation is still limited, but current data suggest that computer-assisted cognitive training improves cognitive performance. OBJECTIVE: The objective of this study was to evaluate the efficacy of combined computer-assisted training supported by home-based neuropsychological training to improve attention, processing speed, memory and executive functions during 3 consecutive months...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28222505/cognitive-training-interventions-for%C3%A2-patients-with-alzheimer-s-disease-a%C3%A2-systematic-review
#3
Eeva-Liisa Kallio, Hanna Öhman, Hannu Kautiainen, Marja Hietanen, Kaisu Pitkälä
BACKGROUND: Cognitive training (CT) refers to guided cognitive exercises designed to improve specific cognitive functions, as well as enhance performance in untrained cognitive tasks. Positive effects of CT on cognitive functions in healthy elderly people and persons with mild cognitive impairment have been reported, but data regarding the effects of CT in patients with dementia is unclear. OBJECTIVE: We systematically reviewed the current evidence from randomized controlled trials (RCTs) to find out if CT improves or stabilizes cognition and/or everyday functioning in patients with mild and moderate Alzheimer's disease...
February 7, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28219026/cognitive-remediation-and-social-cognitive-training-for-violence-in-schizophrenia-a-systematic-review
#4
REVIEW
C Darmedru, C Demily, N Franck
: A significant correlation exists between violence and schizophrenia (SCZ). Recent studies matched some cognitive deficits like strong risk factors for violence with interesting applications in terms of treatment. Our objective was to conduct a systematic review of the effectiveness of cognitive remediation (CR) and social cognitive training (SCT) in the management of violent and aggressive behaviors in SCZ. METHODS: The electronic databases Pubmed, Web of Science, Cochrane Library and ScienceDirect were searched in, using combinations of terms relating to SCZ, CR and violence...
February 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28210957/forced-treadmill-exercise-prevents-spatial-memory-deficits-in-aged-rats-probably-through-the-activation-of-na-k-atpase-in-the-hippocampus
#5
Cláudia Vanzella, Eduardo Farias Sanches, Felipe Kawa Odorcyk, Fabrício Nicola, Janaína Kolling, Aline Longoni, Tiago Marcon Dos Santos, Angela Terezinha de Souza Wyse, Carlos Alexandre Netto
Regular physical activity has shown to improve the quality of life and to prevent age-related memory deficits. Memory processing requires proper regulation of several enzymes such as sodium-potassium adenosine triphosphatase (Na(+), K(+)-ATPase) and acetylcholinesterase (AChE), which have a pivotal role in neuronal transmission. The present study investigated the effects of a treadmill running protocol in young (3 months), mature (6 months) and aged (22 months) Wistar rats, on: (a) cognitive function, as assessed in the Water maze spatial tasks; (b) Na(+), K(+)-ATPase and AChE activities in the hippocampus following cognitive training alone or treadmill running combined with cognitive training...
February 16, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28208604/reducing-fall-risk-with-combined-motor-and-cognitive-training-in-elderly-fallers
#6
Francesco Barban, Roberta Annicchiarico, Matteo Melideo, Alessia Federici, Maria Giovanna Lombardi, Simone Giuli, Claudia Ricci, Fulvia Adriano, Ivo Griffini, Manuel Silvestri, Massimo Chiusso, Sergio Neglia, Sergio Ariño-Blasco, Raquel Cuevas Perez, Yannis Dionyssiotis, Georgios Koumanakos, Milo Kovačeić, Nuria Montero-Fernández, Oscar Pino, Niels Boye, Ulises Cortés, Cristian Barrué, Atia Cortés, Peter Levene, Stelios Pantelopoulos, Roberto Rosso, José Antonio Serra-Rexach, Angelo Maria Sabatini, Carlo Caltagirone
BACKGROUND: Falling is a major clinical problem in elderly people, demanding effective solutions. At present, the only effective intervention is motor training of balance and strength. Executive function-based training (EFt) might be effective at preventing falls according to evidence showing a relationship between executive functions and gait abnormalities. The aim was to assess the effectiveness of a motor and a cognitive treatment developed within the EU co-funded project I-DONT-FALL...
February 10, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28207604/memory-rehabilitation-strategies-in-nonsurgical-temporal-lobe-epilepsy-a-review
#7
Alessandra Del Felice, Marzia Alderighi, Matteo Martinato, Davide Grisafi, Anna Bosco, Pamela J Thompson, Josemir W Sander, Stefano Masiero
People with temporal lobe epilepsy (TLE) who have not undergone epilepsy surgery often complain of memory deficits. Cognitive rehabilitation is employed as a remedial intervention in clinical settings, but research is limited and findings concerning efficacy and the criteria for choosing different approaches have been inconsistent. We aimed to appraise existing evidence on memory rehabilitation in nonsurgical individuals with temporal lobe epilepsy and to ascertain the effectiveness of specific strategies. A scoping review was preferred given the heterogeneous nature of the interventions...
February 15, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28203607/epigallocatechin-gallate-a-useful-therapy-for-cognitive-disability-in-down-syndrome
#8
Fiorenza Stagni, Andrea Giacomini, Marco Emili, Sandra Guidi, Elisabetta Ciani, Renata Bartesaghi
Neurodevelopmental alterations and cognitive disability are constant features of Down syndrome (DS), a genetic condition due to triplication of chromosome 21. DYRK1A is one of the triplicated genes that is thought to be strongly involved in brain alterations. Treatment of Dyrk1A transgenic mice with epigallocatechin gallate (EGCG), an inhibitor of DYRK1A, improves cognitive performance, suggesting that EGCG may represent a suitable treatment of DS. Evidence in the Ts65Dn mouse model of DS shows that EGCG restores hippocampal development, although this effect is ephemeral...
2017: Neurogenesis (Austin, Tex.)
https://www.readbyqxmd.com/read/28182498/control-beliefs-and-cognition-over-a-10-year-period-findings-from-the-active-trial
#9
Jeanine M Parisi, Alden L Gross, Michael Marsiske, Sherry L Willis, George W Rebok
We examined two facets of control beliefs and cognition over 10 years within the Advanced Cognitive Training for Independent and Vital Elderly study. Intellectual Self-Efficacy decreased (β = -0.32 units/year; SE = 0.03) and Concern About Intellectual Aging increased (β = 0.26 units/year; SE = 0.02) over time, with older age being the only predictor of increases in Concern About Intellectual Aging. Although baseline cognitive performance was related to control beliefs over time, the reverse was not supported...
February 2017: Psychology and Aging
https://www.readbyqxmd.com/read/28182471/efficacy-of-cognitive-rehabilitation-using-computer-software-with-individuals-living-with-schizophrenia-a-randomized-controlled-trial-in-japan
#10
Kazuhiko Iwata, Yasuhiro Matsuda, Sayaka Sato, Shunichi Furukawa, Yukako Watanabe, Norifumi Hatsuse, Emi Ikebuchi
OBJECTIVE: Cognitive impairment is common in schizophrenia, and is associated with poor psychosocial functioning. Previous studies had inconsistently shown improvement in cognitive functions with cognitive remediation therapy. This study examined whether cognitive remediation is effective in improving both cognitive and social functions in schizophrenia in outpatient settings that provide learning-based psychiatric rehabilitation. This study is the first randomized controlled trial of cognitive remediation in Japan...
February 9, 2017: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/28168631/cognitive-remediation-for-bipolar-patients-with-objective-cognitive-impairment-a-naturalistic-study
#11
J Veeh, J Kopf, S Kittel-Schneider, J Deckert, A Reif
BACKGROUND: Many bipolar patients (BP) are affected by cognitive impairments and reduced psychosocial function even after complete remission. In the present naturalistic study, we developed a tailored cognitive remediation program (CR) to evaluate the effect on objective and subjective neuropsychological performance, psychosocial functioning and quality of life. METHODS: The CR program used a cognitive training software combined with group sessions to educate cognitive skills...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28164771/a-role-of-the-parasympathetic-nervous-system-in-cognitive-training
#12
Feng Lin, Kathi L Heffner, Ping Ren, Duje Tadin
BACKGROUND: Vision-based speed of processing (VSOP) training can result in broad cognitive improvements in older adults with amnestic mild cognitive impairment (aMCI). What remains unknown, however, is what neurophysiological mechanisms account for the observed training effect. Much of the work in this area has focused on the central nervous system, neglecting the fact that the peripheral system can contributes to changes of the central nervous system and vice versa. OBJECTIVE: We examined the prospective relationship between an adaptive parasympathetic nervous system response to cognitive stimuli and VSOP training-induced plasticity...
February 2, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28162176/-perspectives-of-applying-cognitive-training-in-mild-cognitive-impairment
#13
H L Wang, H M Peng
No abstract text is available yet for this article.
February 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28161695/computerized-cognitive-training-and-brain-derived-neurotrophic-factor-during-bed-rest-mechanisms-to-protect-individual-during-acute-stress
#14
Angelina Passaro, Cecilia Soavi, Uros Marusic, Enrico Rejc, Juana M Sanz, Mario L Morieri, Edoardo Dalla Nora, Voyko Kavcic, Marco V Narici, Carlo Reggiani, Gianni Biolo, Giovanni Zuliani, Stefano Lazzer, Rado Pišot
Acute stress, as bed rest, was shown to increase plasma level of the neurotrophin brain-derived neurotrophic factor (BDNF) in older, but not in young adults. This increase might represent a protective mechanism towards acute insults in aging subjects. Since computerized cognitive training (CCT) is known to protect brain, herein we evaluated the effect of CCT during bed rest on BDNF, muscle mass, neuromuscular function and metabolic parameters. The subjects that underwent CCT did not show an increase of BDNF after bed rest, and showed an anti-insular modification pattern in metabolism...
February 3, 2017: Aging
https://www.readbyqxmd.com/read/28161090/repetitive-transcranial-magnetic-stimulation-combined-with-cognitive-training-for-the-treatment-of-alzheimer-s-disease
#15
Jean-Paul Nguyen, Alcira Suarez, Gilles Kemoun, Michel Meignier, Estelle Le Saout, Philippe Damier, Julien Nizard, Jean-Pascal Lefaucheur
OBJECTIVE: To assess the efficacy of a combination of cognitive training (COG) and repetitive transcranial magnetic stimulation (rTMS), on cognitive performance, locomotor activity, apathy, caregiver burden and dependence of patients with Alzheimer's disease (AD). METHODS: A combination of COG and rTMS was performed in 10 patients with AD (NeuroAD procedure) for a period of 5weeks (one session per day, 5days a week), without maintenance sessions. Patients were evaluated at the end of the treatment (D45) and 6months later (M6) by the Mini Mental State Examination (MMSE), the Alzheimer disease assessment scale - cognitive subscale (ADAS-Cog), various neuropsychological tests and clinical scores specific for locomotor activity, apathy, caregiver burden, and dependence, recorded before the study (baseline)...
February 1, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28152341/an-eye-movement-analysis-of-web-usability-differences-between-older-adults-with-and-without-mild-cognitive-impairment
#16
Marten Haesner, Johan Chandra, Anika Steinert, Elisabeth Steinhagen-Thiessen
Older adults are exposed to computer-based applications daily. However, most websites and applications are not specifically developed for older adults. Studies have shown that older adults with mild cognitive impairment (MCI) behave differently from older adults without MCI in website usage. Eye tracking is a valuable tool to assess users' eye movement behavior in relation to website usability. Understanding the differences in web navigational behavior between older adults with and without MCI would be helpful for developing websites for this target group...
February 2, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28152198/brightening-the-day-with-flashes-of-positive-mental-imagery-a-case-study-of-an-individual-with-depression
#17
Simon E Blackwell, Emily A Holmes
This article presents a case example of an individual with current major depression engaging in a positive mental imagery intervention, specifically a computerized cognitive training paradigm involving repeated practice in generating positive imagery in response to ambiguous scenarios. The patient's reported experience of the intervention suggests the potential of the positive imagery intervention to "brighten" everyday life via promoting involuntary "flashes" of positive mental imagery in situations related to the scenarios, with associated beneficial effects on positive affect, future expectations, and behavior...
February 2, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28139679/mismatch-negativity-is-a-sensitive-and-predictive-biomarker-of-perceptual-learning-during-auditory-cognitive-training-in-schizophrenia
#18
Veronica B Perez, Melissa Tarasenko, Makoto Miyakoshi, Sean T Pianka, Scott D Makeig, David L Braff, Neal R Swerdlow, Gregory A Light
Computerized cognitive training is gaining empirical support for use in the treatment of schizophrenia (SZ). While cognitive training is efficacious for SZ at a group level when delivered in sufficiently intensive doses (eg, 30-50 h), there is variability in individual patient response. The identification of biomarkers sensitive to the neural systems engaged by cognitive training interventions early in the course of treatment could facilitate personalized assignment to treatment. This proof-of-concept study was conducted to determine whether mismatch negativity (MMN), an event-related potential index of auditory sensory discrimination associated with cognitive and psychosocial functioning, would predict gains in auditory perceptual learning and exhibit malleability after initial exposure to the early stages of auditory cognitive training in SZ...
January 31, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28137251/autism-spectrum-disorder-associated-with-49-xyyyy-case-report-and-review-of-the-literature
#19
Caroline Demily, Alice Poisson, Elodie Peyroux, Valérie Gatellier, Alain Nicolas, Caroline Rigard, Caroline Schluth-Bolard, Damien Sanlaville, Massimiliano Rossi
BACKGROUND: Sex chromosome aneuploidies occur in approximately one in 420 live births. The most frequent abnormalities are 45,X (Turner syndrome), 47,XXX (triple X), 47,XXY (Klinefelter syndrome), and 47,XYY. The prevalence of males with more than one extra sex chromosome (e.g. 48,XXYY or 48,XXXY) is less common. However, the literature provides little information about the cognitive and behavioural phenotype and the natural history of the disease. We report the clinical, neurocognitive, social cognitive and psychiatric characterization of a patient with 49,XYYYY syndrome...
January 31, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28132089/effects-of-compensatory-cognitive-training-intervention-for-breast-cancer-patients-undergoing-chemotherapy-a-pilot-study
#20
Jin-Hee Park, Yong Sik Jung, Ku Sang Kim, Sun Hyoung Bae
PURPOSE: Numerous breast cancer patients experience cognitive changes during and after chemotherapy. Chemotherapy-related cognitive impairment can significantly affect quality of life. This pilot study attempted to determine the effects of a compensatory cognitive training on the objective and subjective cognitive functioning of breast cancer patients receiving adjuvant chemotherapy. METHODS: Fifty-four patients were assigned to either a compensatory cognitive training or waitlist condition...
January 28, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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