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https://www.readbyqxmd.com/read/28934810/cross-sectional-imaging-of-solitary-lesions-of-the-neurocranium
#1
Max-Ludwig Schäfer, Arend Koch, Florian Streitparth, Edzard Wiener
Background Although a wide range of processes along the neurocranium are of a benign nature, there are often difficulties in the differential diagnosis. Method In the review CT/MRI scans of the head were evaluated retrospectively regarding solitary lesions along the neurocranium. The majority of the lesions were histologically proven. Results The purpose of the review is to present typical pathologies of the neurocranium and provide a systematic overview based on 12 entities, their locations, prevalence and radiological characteristics...
September 21, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28934809/ct-and-mri-techniques-for-imaging-around-orthopedic-hardware
#2
Thuy Duong Do, Reto Sutter, Stephan Skornitzke, Marc-André Weber
Orthopedic hardware impairs image quality in cross-sectional imaging. With an increasing number of orthopedic implants in an aging population, the need to mitigate metal artifacts in computed tomography and magnetic resonance imaging is becoming increasingly relevant. This review provides an overview of the major artifacts in CT and MRI and state-of-the-art solutions to improve image quality. All steps of image acquisition from device selection, scan preparations and parameters to image post-processing influence the magnitude of metal artifacts...
September 21, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28934801/increasing-rates-of-imaging-in-failed-back-surgery-syndrome-patients-implications-for-spinal-cord-stimulation
#3
S Harrison Farber, Jing L Han, Frank W Petraglia Iii, Robert Gramer, Siyun Yang, Promila Pagadala, Beth Parente, Jichun Xie, Jeffrey R Petrella, Shivanand P Lad
BACKGROUND: Failed back surgery syndrome (FBSS) has a high incidence following spinal surgery, is notoriously refractory to treatment, and results in high health care utilization. Spinal cord stimulation (SCS) is a well-accepted modality for pain relief in this population; however, until recently magnetic resonance imaging (MRI) was prohibited due to risk of heat conduction through the device. OBJECTIVES: We examined trends in imaging use over the past decade in patients with FBSS to determine its impact on health care utilization and implications for patients receiving SCS...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934796/decompressive-l5-transverse-processectomy-for-bertolotti-s-syndrome-a-preliminary-study
#4
Chang Il Ju, Seok Won Kim, Jong Gyue Kim, Seung Myung Lee, Ho Shin, Hyeun Young Lee
BACKGROUND: Bertolotti's syndrome is a spinal disorder characterized by abnormal enlargement of the transverse process of the most caudal lumbar vertebra. The L5 transverse process may be enlarged either unilaterally or bilaterally and may articulate or fuse with the sacrum or ilium. Pseudoarticulation between the transverse process of the L5 and the alar of the sacrum can cause buttock pain and leg pain. In addition, the L4 exiting nerve root could be compressed by an enlarged L5 transverse process...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934788/repeated-ganglion-impar-block-in-a-cohort-of-83-patients-with-chronic-pelvic-and-perineal-pain
#5
Quentin-Come Le Clerc, Thibault Riant, Amelie Levesque, Jean-Jacques Labat, Stephane Ploteau, Roger Robert, Marie-Aimee Perrouin-Verbe, Jerome Rigaud
BACKGROUND: The ganglion impar is the first pelvic ganglion of the efferent sympathetic trunk that relays pelvic and perineal nociceptive messages and therefore constitutes a therapeutic target. OBJECTIVE: The objective of this single-center study was to evaluate the effectiveness of 3 repeated ganglion impar blocks in patients with chronic pelvic and perineal pain on intention-to-treat. STUDY DESIGN: Retrospective single-center study. SETTING: We reviewed the medical records of 83 patients with chronic refractory pelvic and perineal pain...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934706/untreated-hypertension-as-predictor-of-in-hospital-mortality-in-intracerebral-hemorrhage-a-multi-center-study
#6
Mario Hevesi, Eric M Bershad, Mostafa Jafari, Stephan A Mayer, Magdy Selim, Jose I Suarez, Afshin A Divani
PURPOSE: Hypertension is a significant risk factor for intracerebral hemorrhage (ICH). The importance of managing blood pressure to reduce the risk of ICH has been recognized. However, few studies have focused on ICH outcomes due to untreated hypertension. MATERIALS AND METHODS: We conducted a 5-year, retrospective, multicenter study of 490 consecutive ICH patients with histories of untreated-hypertension (n=56), treated-hypertension (n=314), and normotension (n=120)...
September 6, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28934702/effect-of-methyl-substituents-on-the-electronic-transitions-in-simple-meso-aniline-bodipy-based-dyes-ri-cc2-and-td-cam-b3lyp-computational-investigation
#7
Igor K Petrushenko, Konstantin B Petrushenko
The S0→Si, i=1-5 electronic transitions of four 8-(4-aniline)-BODIPY and four 8-(N,N-dimethyl)-BODIPY dyes, differ by number and position of methyl substituents in the BODIPY frame, were investigated theoretically using ab initio the coupled cluster doubles (CC2) and TD-CAM-B3LYP methods. Methyl substituents in the BODIPY frame and the aniline fragment at the meso position disturb energy of local excitations S0→S1, S0→S3, and S0→S4 weakly in comparison with the fully unsubstituted BODIPY molecule. These transitions in experimental spectra form the most long-wave absorption bands at ca...
September 13, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28934535/quantification-of-imaging-error-in-the-measurement-of-cup-position-a-cadaveric-comparison-of-radiographic-and-computed-tomography-imaging
#8
Ran Schwarzkopf, Jonathan M Vigdorchik, Theodore T Miller, Eric A Bogner, Jeffrey M Muir, Michael B Cross
Postoperative radiographs remain the standard for assessment of component placement following total hip arthroplasty (THA), despite the known limitations of radiographs. Computed tomography (CT) scanning offers improved accuracy, but its costs and radiation exposure are prohibitive. The authors performed a cadaver study to compare the error associated with radiographs with that of CT scans following THA. The authors also compared imaging with a novel mini-navigation system. Three board-certified orthopedic surgeons each performed 4 THA procedures (6 cadavers, 12 hips) via the posterior approach using a mini-navigation tool to assist with component placement...
September 21, 2017: Orthopedics
https://www.readbyqxmd.com/read/28934363/sex-related-differences-in-the-risk-factors-for-in-hospital-mortality-and-outcomes-of-ischemic-stroke-patients-in-rural-areas-of-taiwan
#9
Cheung-Ter Ong, Yi-Sin Wong, Sheng-Feng Sung, Chi-Shun Wu, Yung-Chu Hsu, Yu-Hsiang Su, Ling-Chien Hung
BACKGROUND AND PURPOSE: Sex-related differences in the clinical presentation and outcomes of stroke patients are issues that have attracted increased interest from the scientific community. The present study aimed to investigate sex-related differences in the risk factors for in-hospital mortality and outcome in ischemic stroke patients. METHODS: A total of 4278 acute ischemic stroke patients admitted to a stroke unit between January 1, 2007 and December 31, 2014 were included in the study...
2017: PloS One
https://www.readbyqxmd.com/read/28934340/using-rna-seq-data-to-select-reference-genes-for-normalizing-gene-expression-in-apple-roots
#10
Zhe Zhou, Peihua Cong, Yi Tian, Yanmin Zhu
Gene expression in apple roots in response to various stress conditions is a less-explored research subject. Reliable reference genes for normalizing quantitative gene expression data have not been carefully investigated. In this study, the suitability of a set of 15 apple genes were evaluated for their potential use as reliable reference genes. These genes were selected based on their low variance of gene expression in apple root tissues from a recent RNA-seq data set, and a few previously reported apple reference genes for other tissue types...
2017: PloS One
https://www.readbyqxmd.com/read/28934249/variability-in-objective-and-subjective-measures-affects-baseline-values-in-studies-of-patients-with-copd
#11
Wayne H Anderson, Jae Wook Ha, David J Couper, Wanda K O'Neal, R Graham Barr, Eugene R Bleecker, Elizabeth E Carretta, Christopher B Cooper, Claire M Doerschuk, M Bradley Drummond, MeiLan K Han, Nadia N Hansel, Victor Kim, Eric C Kleerup, Fernando J Martinez, Stephen I Rennard, Donald Tashkin, Prescott G Woodruff, Robert Paine, Jeffrey L Curtis, Richard E Kanner
RATIONALE: Understanding the reliability and repeatability of clinical measurements used in the diagnosis, treatment and monitoring of disease progression is of critical importance across all disciplines of clinical practice and in clinical trials to assess therapeutic efficacy and safety. OBJECTIVES: Our goal is to understand normal variability for assessing true changes in health status and to more accurately utilize this data to differentiate disease characteristics and outcomes...
2017: PloS One
https://www.readbyqxmd.com/read/28934238/a-tool-to-automatically-analyze-electromagnetic-tracking-data-from-high-dose-rate-brachytherapy-of-breast-cancer-patients
#12
Th I Götz, G Lahmer, V Strnad, Ch Bert, B Hensel, A M Tomé, E W Lang
During High Dose Rate Brachytherapy (HDR-BT) the spatial position of the radiation source inside catheters implanted into a female breast is determined via electromagnetic tracking (EMT). Dwell positions and dwell times of the radiation source are established, relative to the patient's anatomy, from an initial X-ray-CT-image. During the irradiation treatment, catheter displacements can occur due to patient movements. The current study develops an automatic analysis tool of EMT data sets recorded with a solenoid sensor to assure concordance of the source movement with the treatment plan...
2017: PloS One
https://www.readbyqxmd.com/read/28934225/harmonizing-the-pixel-size-in-retrospective-computed-tomography-radiomics-studies
#13
Dennis Mackin, Xenia Fave, Lifei Zhang, Jinzhong Yang, A Kyle Jones, Chaan S Ng, Laurence Court
Consistent pixel sizes are of fundamental importance for assessing texture features that relate intensity and spatial information in radiomics studies. To correct for the effects of variable pixel sizes, we combined image resampling with Butterworth filtering in the frequency domain and tested the correction on computed tomography (CT) scans of lung cancer patients reconstructed 5 times with pixel sizes varying from 0.59 to 0.98 mm. One hundred fifty radiomics features were calculated for each preprocessing and field-of-view combination...
2017: PloS One
https://www.readbyqxmd.com/read/28933972/visual-acuity-and-macular-and-peripapillary-thickness-in-high-myopia
#14
Solmaz Abdolrahimzadeh, Francesco Parisi, Andrea Maria Plateroti, Federica Evangelista, Vito Fenicia, Gianluca Scuderi, Santi Maria Recupero
PURPOSE: To investigate best corrected visual acuity (BCVA), and choroidal and retinal thickness values between high myopes without myopic maculopathy and emmetropes. MATERIALS AND METHODS: Case control study where 53 myopes with axial length (AL) above 26 mm without myopic maculopathy and 53 age-matched emmetropes with AL between 21.50 and 24.50 were included as controls. Complete ophthalmological examination and biometry were performed. Choroidal and individual retinal layer thickness maps using spectral domain optical coherence tomography were obtained in the macular and peripapillary area with enhanced depth imaging...
September 21, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28933536/a-bimetallic-silver-neodymium-theranostic-nanoparticle-with-multimodal-nir-mri-ct-imaging-and-combined-chemo-photothermal-therapy
#15
Sandeep K Mishra, S Kannan
An engineered metallic nanostructure is an excellent candidate for "theranosis" of cancer, having intrinsic properties of multimodal imaging and therapy. Toward this target, the development of silver-neodymium bimetallic nanoparticles (Ag-Nd BNPs) via microwave-assisted polyol synthesis is presented. The resultant Ag-Nd BNPs exhibit good monodispersity with average size of 10 nm, fluorescence in the near-infrared (NIR) region, and magnetic properties. The Ag-Nd BNPs also validate MRI, CT, and NIR trimodal imaging ability and enunciate valuable temperature response upon irradiation under a NIR laser...
September 21, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28933358/substrate-deprivation-therapy-to-reduce-glycosaminoglycan-synthesis-improves-aspects-of-neurological-and-skeletal-pathology-in-mps-i-mice
#16
Ainslie L K Derrick-Roberts, Matilda R Jackson, Carmen E Pyragius, Sharon Byers
Mucopolysaccharidosis type I (MPS I) is the most common form of the MPS group of genetic diseases. MPS I results from a deficiency in the lysosomal enzyme α-l-iduronidase, leading to accumulation of undegraded heparan and dermatan sulphate glycosaminoglycan (GAG) chains in patient cells. MPS children suffer from multiple organ failure and die in their teens to early twenties. In particular, MPS I children also suffer from profound mental retardation and skeletal disease that restricts growth and movement. Neither brain nor skeletal disease is adequately treated by current therapy approaches...
February 23, 2017: Diseases (Basel)
https://www.readbyqxmd.com/read/28933333/-canine-elbow-humeroulnar-incongruity-measurements-using-computed-tomography
#17
R Snášil, P Proks, A Nečasová, K Michalčáková, A Nečas
PURPOSE OF THE STUDY The purpose of the study is to compare the repeatability and reproducibility of quantitative and subjective evaluation of elbow humeroulnar incongruity (HUI) using computed tomography (CT) on an in vivo canine model. MATERIAL AND METHODS HUI was evaluated on canine (n = 50) elbow joints (n = 100). The computed tomography of elbow joints was performed under intravenous sedation. Multiplanar reconstructions (MPR) were produced. HUI was evaluated on sagittal MPR images subjectively and by measuring the subluxation index (SI)...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28933329/-mid-term-to-long-term-results-of-revision-total-hip-arthroplasty-using-the-oval-shaped-acetabular-cup-tc-type
#18
E Šťastný, T Trč, J Frýdl, Z Kopečný, T Philippou, J Lisý
INTRODUCTION The purpose of our paper is to evaluate the mid-term to long-term results and to confirm the basic criteria of a high-quality revision implant: safe bridging of bone defects, achievement of reliable primary fixation of revision acetabular cup, achievement of good secondary stability with documentable osteointegration of cup and demonstration of remodelling of transplanted bone tissue in the area of defects and in spaces between the implant ribs. MATERIAL AND METHODS Altogether 36 patients (38 cups) were evaluated who had undergone revision hip arthroplasty in the period from 2004 to 2010...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28933270/11c-choline-pet-ct-based-helical-tomotherapy-as-treatment-approach-for-bone-metastases-in-recurrent-prostate-cancer-patients
#19
Elena Incerti, Vincenzo Gangemi, Paola Mapelli, Chiara Lucrezia Deantoni, Giampiero Giovacchini, Federico Fallanca, Andrei Fodor, Andrea Ciarmiello, Sergio Baldari, Luigi Gianolli, Nadia Di Muzio, Maria Picchio
To evaluate the efficacy of 11C-choline PET/CT (CHO-PET/CT) based helical tomotherapy (HTT) as a therapeutic approach for bone metastases in recurrent prostate cancer (PCa) patients. METHODS This retrospective study includes 20 PCa patients (median age: 67; range: 51-80 years) presenting biochemical relapse after primary treatment who underwent CHO-PET/CT based HTT on positive bone metastases from December 2007 to June 2014. The effectiveness of HTT assessed with biochemical response at 3/6/12 months, biochemical relapse free survival (bRFS) and overall survival (OS) at 2 years...
September 19, 2017: Current Radiopharmaceuticals
https://www.readbyqxmd.com/read/28933047/the-right-touch-stroking-of-ct-innervated-skin-promotes-vocal-emotion-processing
#20
Annett Schirmer, Thomas C Gunter
Research has revealed a special mechanoreceptor, called C-tactile (CT) afferent, that is situated in hairy skin and that seems relevant for the processing of social touch. We pursued a possible role of this receptor in the perception of other social signals such as a person's voice. Participants completed three sessions in which they heard surprised and neutral vocal and nonvocal sounds and detected rare sound repetitions. In a given session, participants received no touch or soft brushstrokes to the arm (CT innervated) or palm (CT free)...
September 20, 2017: Cognitive, Affective & Behavioral Neuroscience
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