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https://www.readbyqxmd.com/read/28153536/kounis-syndrome-a-review-article-on-epidemiology-diagnostic-findings-management-and-complications-of-allergic-acute-coronary-syndrome
#1
REVIEW
Mahmoud Abdelghany, Rogin Subedi, Siddharth Shah, Hani Kozman
Kounis syndrome (KS) is a hypersensitivity coronary disorder induced by exposure to drugs, food, environmental and other triggers. Vasospastic allergic angina, allergic myocardial infarction (MI) and stent thrombosis with occluding thrombus infiltrated by eosinophils and/or mast cells constitute the three main variants of this syndrome. We reviewed 175 patients who fulfilled the definition of one of the three types of KS. The epidemiology, diagnostic findings, management and complications were reviewed in this article...
April 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28123625/vasospastic-myocardial-infarction-an-even-rarer-occurrence-of-a-rare-entity
#2
Cem Ertan, Mehmet Emre Özpelit, Önder Limon, Deniz Oray, Nihat Pekel
No abstract text is available yet for this article.
2017: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28119443/measuring-physical-stigmata-of-niacin-associated-skin-toxicity-by-colorimetry-white-light-spectroscopy-laser-doppler-flowmetry-and-thermometry-in-combination-with-symptom-perception-scoring-methods-to-aid-development-of-niacin-mimetics
#3
Richard L Dunbar, Harsh Goel, Sony Tuteja, Wen-Liang Song, Grace Nathanson, Zeeshan Babar, Dusanka Lalic, Joel M Gelfand, Daniel J Rader, Gary L Grove
Though cardioprotective, niacin monotherapy is limited by unpleasant cutaneous symptoms mimicking dermatitis: Niacin-Associated Skin Toxicity (NASTy). Niacin is prototypical of several emerging drugs suffering off-target rubefacient properties, whereby agonizing the GPR109A receptor on cutaneous immune cells provokes vasodilation, prompting skin plethora and rubor, as well as dolor, tumor, and calor, and systemically, heat loss, frigor, chills, and rigors. Typically, NASTy effects are described by subjective, patient-reported perception, at best semi-quantitative and bias-prone...
January 23, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/28087290/inferior-j-waves-in-patients-with-vasospastic-angina-might-be-a-risk-factor-for-ventricular-fibrillation
#4
Tomoko Fumimoto, Takeshi Ueyama, Akihiko Shimizu, Yasuhiro Yoshiga, Makoto Ono, Takayoshi Kato, Hironori Ishiguchi, Takayuki Okamura, Jutaro Yamada, Masafumi Yano
BACKGROUND: There is little information about the relationship between J waves and the occurrence of ventricular fibrillation (VF) in patients with vasospastic angina (VSA). The present study aimed to assess the incidence of J waves and the occurrence of VF in patients with VSA. METHODS: The subjects consisted of 62 patients with VSA diagnosed by acetylcholine provocation tests in our institution from 2002 to 2014. We investigated the VF events, prevalence of J waves, and relationship between the VF events and J waves...
January 10, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28040441/recurrent-vasospastic-myocardial-infarctions-and-hand-necrosis
#5
Florian Rey, Marco Roffi, Cindy Bouvet, Romain Bréguet, Peter Jandus, Fabio Rigamonti
No abstract text is available yet for this article.
January 23, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28038722/management-standards-for-stable-coronary-artery-disease-in-india
#6
Sundeep Mishra, Saumitra Ray, Jamshed J Dalal, J P S Sawhney, S Ramakrishnan, Tiny Nair, S S Iyengar, V K Bahl
Coronary artery disease (CAD) is one of the important causes of cardiovascular morbidity and mortality globally, giving rise to more than 7 million deaths annually. An increasing burden of CAD in India is a major cause of concern with angina being the leading manifestation. Stable coronary artery disease (SCAD) is characterised by episodes of transient central chest pain (angina pectoris), often triggered by exercise, emotion or other forms of stress, generally triggered by a reversible mismatch between myocardial oxygen demand and supply resulting in myocardial ischemia or hypoxia...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28005169/paroxysmal-atrial-fibrillation-during-intracoronary-acetylcholine-provocation-test
#7
Yuichi Saito, Hideki Kitahara, Toshihiro Shoji, Satoshi Tokimasa, Takashi Nakayama, Kazumasa Sugimoto, Yoshihide Fujimoto, Yoshio Kobayashi
Intracoronary acetylcholine (ACh) provocation test is useful to diagnose vasospastic angina. However, paroxysmal atrial fibrillation (AF) often occurs during intracoronary ACh provocation test, leading to disabling symptoms. The aim of this study was to investigate the incidence and predictors of paroxysmal AF during the test. A total of 377 patients without persistent AF who underwent intracoronary ACh provocation test were included. Paroxysmal AF during ACh provocation test was defined as documented AF on electrocardiogram during the procedure...
December 22, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27969863/tct-499-influence-of-gender-on-the-clinical-characteristics-and-prognostic-factors-in-patients-with-vasospastic-angina
#8
da Hyon Lee, Jeong Hoon Yang, Joo Yong Hahn, Cláudia Jorge, Sang Hoon Lee, Fausto J Pinto, Seung-Hyuk Choi
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969856/tct-498-lower-mortality-in-patients-with-vasospastic-angina-who-receive-statin-therapy-data-from-the-asan-vasospastic-angina-registry
#9
Cheol Hyun Lee, Osung Kwon, Ungjeong Do, Jung Ae Hong, Kyusup Lee, Min Soo Cho, Jaeseok Bae, Do-Yoon Kang, Se Hun Kang, Pil Hyung Lee, Sung-Han Yoon, Jung-Min Ahn, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Seung-Jung Park
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27939277/thrombus-and-plaque-erosion-characterized-by-optical-coherence-tomography-in-patients-with-vasospastic-angina
#10
Eun-Seok Shin, Ae-Young Her, Soe Hee Ann, Gillian Balbir Singh, Heeyoun Cho, Eui Cheol Jung, Eun Bo Shim, Bon-Kwon Koo, Takashi Akasaka
INTRODUCTION AND OBJECTIVES: Vasospastic angina (VSA) can result in endothelial damage and thrombus formation. The aim of this study was to evaluate the incidence of thrombus and plaque characteristics at coronary spasm segments compared with nonspasm segments by using optical coherence tomography (OCT) in patients with suspected VSA. METHODS: One hundred and eighty-three patients with suspected VSA were enrolled in this study. The ergonovine provocation test was performed in all patients for the diagnosis of VSA except in patients with spontaneous spasm...
December 6, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27921167/the-real-world-in-the-clinic-before-and-after-the-establishment-of-guidelines-for-coronary-artery-spasm-a-questionnaire-for-members-of-the-japanese-cine-angio-association
#11
Shozo Sueda, Hiroaki Kohno, Hideaki Yoshino
We investigated the clinical situations and the present knowledge of Japanese cardiologists about coronary artery spasm before and after the establishment of guidelines for this condition in the real world. A questionnaire was developed regarding the number of cases of coronary angiography, percutaneous coronary intervention, and invasive/non-invasive spasm provocation tests before (2008) and after (2014) the establishment of the Japanese Circulation Society (JCS) guidelines for coronary artery spasm and the status of spasm provocation tests...
December 5, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27904032/coronary-microvascular-dysfunction%C3%A3-epidemiology-pathogenesis-prognosis-diagnosis-risk-factors-and-therapy
#12
REVIEW
Cheng Chen, Janet Wei, Ahmed AlBadri, Parham Zarrini, C Noel Bairey Merz
Angina has traditionally been thought to be caused by obstructive coronary artery disease (CAD). However, a substantial number of patients with angina are found to not have obstructive CAD when undergoing coronary angiography. A significant proportion of these patients have coronary microvascular dysfunction (CMD), characterized by heightened sensitivity to vasoconstrictor stimuli and limited microvascular vasodilator capacity. With the advent of non-invasive and invasive techniques, the coronary microvasculature has been more extensively studied in the past 2 decades...
December 22, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27884129/in-vivo-optical-coherence-tomography-visualization-of-intraplaque-neovascularization-at-the-site-of-coronary-vasospasm-a-case-report
#13
Kenichi Tsujita, Koichi Kaikita, Satoshi Araki, Toshihiro Yamada, Suguru Nagamatsu, Kenshi Yamanaga, Kenji Sakamoto, Sunao Kojima, Seiji Hokimoto, Hisao Ogawa
BACKGROUND: Coronary plaques in patients with coronary vasospastic angina have been characterized by diffuse intima-media thickening with homogeneous fibrous tissue, without confluent necrotic tissue. However, coronary vasospasm can trigger coronary thrombosis, and may play an important role in the pathogenesis of acute coronary syndromes, though the precise morphological mechanisms underlying this process remain unclear. CASE PRESENTATION: A 43-year-old man with a history of multivessel coronary vasospastic angina had been treated with long-acting diltiazem and fluvastatin since 2004...
November 25, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27873006/feasibility-of-omitting-provocation-test-with-50%C3%A2-%C3%AE-g-of-acetylcholine-in-left-coronary-artery
#14
Yuichi Saito, Hideki Kitahara, Toshihiro Shoji, Satoshi Tokimasa, Takashi Nakayama, Kazumasa Sugimoto, Yoshihide Fujimoto, Yoshio Kobayashi
According to the Japanese Circulation Society guideline of vasospastic angina, incremental doses of acetylcholine (ACh) are prescribed for coronary spasm provocation: 20 and 50 μg for the right coronary artery (RCA), and 20, 50 and 100 μg for the left coronary artery (LCA). However, provocation by low doses of ACh in patients with low vasoreactivity may be less needed, and the requirement of 50 μg of ACh for the LCA in these patients has not been evaluated. In the present study, patients who underwent ACh provocation test for both the RCA and LCA were included...
November 21, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27856130/overview-of-the-pharmacological-spasm-provocation-test-comparisons-between-acetylcholine-and-ergonovine
#15
REVIEW
Shozo Sueda, Hiroaki Kohno, Takaaki Ochi, Tadao Uraoka, Kensuke Tsunemitsu
The spasm provocation tests of ergonovine and acetylcholine have been employed in the cardiac catheterization laboratory. Ergonovine acts through the serotogenic receptors, while acetylcholine acts through the muscarinic cholinergic receptors. Different mediators may have the potential to cause different coronary responses. However, there are few reports concerning the coronary response between ergonovine and acetylcholine in the same patients. Acetylcholine is supersensitive for females; spasm provoked by ergonovine is focal and proximal, whereas provoked spasm by acetylcholine is diffuse and distal...
January 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/27852592/clinical-outcomes-of-vasospastic-angina-patients-presenting-with-acute-coronary-syndrome
#16
Sung Woo Cho, Taek Kyu Park, Hye Bin Gwag, A Young Lim, Min Seok Oh, Da Hyon Lee, Choong Sil Seong, Jeong Hoon Yang, Young Bin Song, Joo-Yong Hahn, Jin-Ho Choi, Sang Hoon Lee, Hyeon-Cheol Gwon, Seung-Hyuk Choi
BACKGROUND: Coronary vasospasm is an important pathogenesis of acute coronary syndrome (ACS). However, the clinical features and prognosis of vasospastic angina (VA) patients presenting with ACS (VAACS) are still unclear. We aimed to evaluate the clinical characteristics and long-term outcomes of VAACS patients without significant coronary artery stenosis. METHODS AND RESULTS: A total of 986 VA patients confirmed by ergonovine provocation test were analyzed. VAACS was defined as VA patients visiting the emergency room with documented electrocardiographic changes, significant arrhythmias, or elevated cardiac biomarkers...
November 16, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27826349/life-threatening-complication-of-self-made-remedy-for-controlling-high-blood-pressure-coronary-artery-vasospasm-associated-with-iatrogenic-thyrotoxicosis
#17
In Sook Kang, Wook Bum Pyun
We report the case of a middle aged woman who was previously diagnosed with hypertension. She had been drinking a kelp concentrate solution daily for her hypertension instead of taking the prescribed medicine due to her personal beliefs about the kelp solution. As a consequence, she experienced vasospastic angina complicated by myocardial infarction and cardiogenic syncope resulting from iatrogenic thyrotoxicosis. Complementary medicine is widely used by the general population. However, there is still a lack of evidence regarding their efficacy and safety...
November 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27817850/-is-coronary-artery-spasm-a-disease-specific-to-women
#18
X Halna du Fretay, M A Bouzid, B Blanchard-Lemoine, H Benamer
Vasospastic angina is considered rare in Europe but with a prevalence probably underestimated and affects preferentially men in published studies, mostly involving Asian populations. Vasospastic angina in the female population have specificities in terms of pathophysiology, clinical presentation and prognosis, as well as diagnostic strategies currently recommended, that we describe from a clinical case. Although known for over 50years, vasospastic angina remains a disease still insufficiently researched, probably even less in women...
December 2016: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/27764071/recognizing-and-treating-vasospastic-angina
#19
Leon Chen, Fidelindo Lim
No abstract text is available yet for this article.
November 19, 2016: Nurse Practitioner
https://www.readbyqxmd.com/read/27749585/a-case-report-of-the-beneficial-effects-of-botulinum-toxin-type-a-on-raynaud-phenomenon-in-a-patient-with-lung-cancer
#20
Lu Wang, Qi-Song Lei, Yu-Ying Liu, Guan-Jie Song, Chun-Ling Song
OBJECTIVE: Raynaud phenomenon is a vasospastic disorder affecting the hands and feet, and the efficacies of traditional treatments, such as pharmacological therapies and sympathectomy, are not uniform. Patients with paraneoplastic Raynaud phenomenon do not benefit from the traditional treatments. The use of botulinum toxin type A (BTX-A) for Raynaud phenomenon has been reported for several years; however, there are few reports regarding botulinum toxin type A in the treatment of paraneoplastic Raynaud phenomenon...
October 2016: Medicine (Baltimore)
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