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https://www.readbyqxmd.com/read/28637516/feeding-heat-oxidized-oil-to-dairy-cows-affects-milk-fat-nutritional-quality
#1
M Kaleem, F Enjalbert, Y Farizon, A Meynadier
Heating oil and oilseeds results in oxidation products that affect ruminal biohydrogenation of polyunsaturated fatty acids, altering milk fatty acids profile, and could be transferred to milk. An experiment was conducted to investigate the effects of oil heating on rumen and milk fatty acids profile and the transfer of oxidation products to milk. Sunflower oil was heated at 150°C for 15 h and given to lactating dairy cows in a 2×2 arrangement: two groups of two cows, equipped with a ruminal cannula and receiving two diets (containing either heated or unheated oil) during two experimental periods...
June 22, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28626143/effect-of-conjugated-linoleic-acid-intake-on-endurance-exercise-performance-and-anti-fatigue-in-student-athletes
#2
Naoko Terasawa, Ken Okamoto, Kenta Nakada, Kazumi Masuda
Conjugated linoleic acids (CLA) intake has been reported to reduce body fat mass or increase lean body mass and to improve exercise outcome by modulating testosterone in humans. These reports have studied mostly overweight subjects; few were athletes. Therefore, in this study, the effect of CLA intake on endurance performance and anti-fatigue in student athletes was investigated. A double-blind, crossover study was conducted with 10 male student athletes. Each subject was administered with either CLA (net 0...
June 13, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28618976/bromelain-decorated-hybrid-nanoparticles-based-on-lactobionic-acid-conjugated-chitosan-for-in%C3%A2-vitro-anti-tumor-study
#3
Bing Wei, Le He, Xin Wang, Guo Qing Yan, Jun Wang, Rupei Tang
In this work, lactobionic acid-modified chitosan (CLA) was chosen as an initial material to prepare tumor-targeted nanoparticles (CLA NPs). To improve the nanoparticles' tumor penetration ability, bromelain was then decorated on the surface of CLA NPs to give CLAB NPs. The micromorphology of CLA and CLAB NPs was observed by transmission electron microscopy and scanning electron microscopy. The stability of CLA and CLAB NPs was then investigated at different pH values (4.0-9.0) and physiological environment by dynamic light scattering...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28608585/effect-of-dietary-conjugated-linoleic-acid-on-vitamin-a-status-of-lactating-rats-and-their-offspring
#4
J O Zeitz, E Most, K Eder
The absorption and metabolism of vitamin A is linked with that of lipids. It is known that conjugated linoleic acid (CLA) affects the lipid metabolism in growing and lactating animals. In the present study, the hypothesis was investigated that dietary CLA influences vitamin A status of lactating rats and their pups during the suckling period. For this purpose, Wistar Han rats were fed either a control diet (control group, n = 14) or a diet containing 0.87% of cis-9, trans-11 and trans-10, cis-12 (1:1) CLA (CLA group, n = 14) during pregnancy and lactation...
June 13, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28601883/skin-homing-il-13-producing-t-cells-expand-in-the-circulation-of-patients-with-drug-rash-with-eosinophilia-and-systemic-symptoms
#5
Yuichi Teraki, Tomoo Fukuda
BACKGROUND: Drug rash with eosinophilia and systemic symptoms (DRESS), also known as drug-induced hypersensitivity syndrome, is characterized by severe drug-induced reactions with extensive cutaneous lesions and visceral involvement. Although T cell-mediated hypersensitivity reactions to drugs may be involved in the pathogenesis of DRESS, there is limited data regarding the T-cell phenotypes responsible for the pathogenesis of DRESS. OBJECTIVE AND METHODS: Using flow cytometry, we investigated the cytokine profiles and cutaneous lymphocyte antigen (CLA) expression in circulating T cells in patients with DRESS...
June 10, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28601680/nitric-oxide-induces-human-cla-cd25-foxp3-regulatory-t-cells-with-skin-homing-potential
#6
Cunjing Yu, Amanda Fitzpatrick, Duanduan Cong, Chengcan Yao, Jinah Yoo, Andrew Turnbull, Jürgen Schwarze, Mary Norval, Sarah E M Howie, Richard B Weller, Anne L Astier
Phototherapy releases nitric oxide and can reduce symptoms in Atopic Dermatitis (AD). Nitric oxide induced suppressive regulatory T cells and, post-phototherapy, a clinical improvement in AD correlated with an increased ratio of Tregulatory:Teffector cells.
June 7, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28601449/fatty-acid-profile-of-goat-milk-in-diets-supplemented-with-chia-seed-salvia-hispanica-l
#7
B Schettino, S Vega, R Gutiérrez, A Escobar, J Romero, E Domínguez, M González-Ronquillo
Chia seed (Salvia hispanica L.) is the greatest known plant source of n-3 α-linolenic acid. The present study evaluated the effects of 3 inclusion levels of chia seed [zero (control); low, 2.7% (CLow); and high, 5.5% (CHigh)] in diets of dairy goats on milk yield and fatty acid profile. Nine Saanen dairy goats in the last third of lactation period, live weight 38 ± 8.7 kg, housed in metabolic cages, were fed iso-proteic and iso-energetic (160 g of crude protein/d and 11 MJ of metabolizable energy/d) diets...
June 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28601035/effects-of-dietary-cla-supplementation-parity-and-different-concentrate-levels-before-calving-on-immunoglobulin-g1-g2-and-m-concentrations-in-dairy-cows
#8
Melanie Eger, Jana Horn, Jamal Hussen, Hans-Joachim Schuberth, Maria Scharf, Ulrich Meyer, Sven Dänicke, Hartwig Bostedt, Gerhard Breves
Peripartal dairy cows exhibit a higher susceptibility for infectious diseases, which might be linked to the negative energy balance occurring at the onset of lactation. A dietary supplementation of conjugated linoleic acids (CLA) may reduce milk fat yield and subsequently lower the energy deficit. The utilization of immunoglobulins (Ig) for colostrogenesis might impair humoral immunity in peripartal dairy cows; therefore this study investigated the effects of a CLA supplement, parity and different dietary energy levels on plasma and colostrum IgG1, IgG2 and IgM levels in dairy cows and their calves...
June 2, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28600044/transvaginal-endoscopic-surgery-assisted-versus-conventional-laparoscopic-adnexectomy-tvea-vs-cla-a-propensity-matched-study-and-literature-review
#9
Yi-Chieh Li, Fei-Chun Ku, Hsin-Hong Kuo, Hsiao-Jung Tseng, Chin-Jung Wang
OBJECTIVE: Natural orifice transluminal endoscopic surgery (NOTES) may be useful in gynecologic endoscopic surgery. This study evaluated the efficacy, safety, and perioperative outcomes of combined NOTES and vaginal approach, transvaginal endoscopic surgery-assisted adnexectomy (TVEA), for the surgical treatment of presumed benign ovarian tumors. MATERIALS AND METHODS: Records were reviewed for 33 consecutive TVEA procedures performed between May 2011 and March 2014...
June 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28592972/fabrication-of-polycaprolactone-polyurethane-loading-conjugated-linoleic-acid-and-its-antiplatelet-adhesion
#10
Ho Hieu Minh, Nguyen Thi Hiep, Nguyen Dai Hai, Vo Van Toi
Polycaprolactone/polyurethane (PCL/PU) fibrous scaffold was loaded with conjugated linoleic acid (CLA) by electrospinning method to improve the hemocompatibility of the polymeric surface. Fourier Transform Infrared Spectroscopy (FT-IR) analysis and Scanning Electron Microscopy (SEM) observation were employed to characterize the chemical structure and the changing morphology of electrospun PCL/PU and PCL/PU loaded with CLA (PCL/PU-CLA) scaffolds. Platelet adhesion and whole blood clot formation tests were used to evaluate the effect of CLA on antithrombotic property of PCL/PU-CLA scaffold...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28573846/simultaneous-fluorescence-and-chemiluminescence-turned-on-by-aggregation-induced-emission-for-real-time-monitoring-of-endogenous-superoxide-anion-in-live-cells
#11
Jinye Niu, Jilin Fan, Xu Wang, Yongsheng Xiao, Xilei Xie, Xiaoyun Jiao, Chuanzhi Sun, Bo Tang
Biological sensors with simultaneous turn-on signals of fluorescence (FL) and chemiluminescence (CL) triggered by one single species are supposed to integrate spatiotemporally resolved FL imaging with dynamic CL sensing into one luminescent assay. Efficiently increased accuracy can be expected based on complementary information simultaneously obtained from two independent modes, which is crucial in disease detection and diagnosis. However, very few examples can be found to date because of the key challenges in the rational design of sensing structures...
June 15, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28560368/ultra-low-fouling-methylimidazolium-modified-surfaces-for-the-detection-of-her2-in-breast-cancer-cell-lysates
#12
Alexandra Aubé, Shirley Campbell, Andreea R Schmitzer, Audrey Claing, Jean-François Masson
We synthesized novel ultra-low fouling ionic liquids and demonstrated their use with surface plasmon resonance (SPR) sensing for the analysis of HER2 in breast cancer cell lysates. Whilst biomarkers are commonly detected in serum, this remains challenging for cancer diagnosis due to their low concentrations in circulation and in some cases, there is a poor correlation between serum and tissue concentrations. Therefore, a cell lysate constitutes an interesting biosample for cancer diagnosis and typing, which has been largely unexploited for chemical biosensing of cancer biomarkers...
May 31, 2017: Analyst
https://www.readbyqxmd.com/read/28559164/pomegranate-seed-oil-influences-the-fatty-acids-profile-and-reduces-the-activity-of-desaturases-in-livers-of-sprague-dawley-rats
#13
Agnieszka Białek, Agnieszka Stawarska, Joanna Bodecka, Małgorzata Białek, Andrzej Tokarz
The aim of our study was to compare the influence of diet supplementation with pomegranate seed oil - as conjugated linolenic acids (CLnA) source, or conjugated linoleic acids (CLA) and to examine the mechanism of their activity. The content of fatty acids, levels of biomarkers of lipids' oxidation and the activity of key enzymes catalyzing lipids metabolism were measured. Obtained results revealed that conjugated fatty acids significantly decrease the activity of Δ5-desaturase (p=0.0001) and Δ6-desaturase (p=0...
May 27, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28556504/effects-of-conjugated-linoleic-acid-supplementation-on-serum-c-reactive-protein-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#14
REVIEW
Mohsen Mazidi, Ehsan Karimi, Peyman Rezaie, Gordon A Ferns
AIM: To undertake a systematic review and meta-analysis of prospective studies to determine the effect of conjugated linoleic acids (CLAs) supplementation on serum C-reactive protein (CRP). METHOD: PubMed-Medline, Web of Science, Cochrane Database and Google Scholar databases were searched (up until May 2016) to identify prospective studies evaluating the impact of CLAs supplementation on serum CRP. Random effects models meta-analysis was used for quantitative data synthesis...
May 29, 2017: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/28555193/helicobacter-pylori-from-peptic-ulcer-patients-in-uganda-is-highly-resistant-to-clarithromycin-and-fluoroquinolones-results-of-the-genotype-helicodr-test-directly-applied-on-stool
#15
Denish Calmax Angol, Ponsiano Ocama, Tess Ayazika Kirabo, Alfred Okeng, Irene Najjingo, Freddie Bwanga
BACKGROUND: Around 70-90% of peptic ulcer disease (PUD) is due to Helicobacter pylori and requires treatment with antimicrobials to which these bacteria are susceptible. Common H. pylori diagnostic tests do not provide drug susceptibility data. Using the GenoType HelicoDR PCR test designed for gastric biopsies for simultaneous detection of H. pylori and its resistance to clarithromycin (CLA)/fluoroquinolones (FLQ), we present evidence for stool as an optional test specimen and also provide data on prevalence of H...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28550898/pain-after-single-incision-versus-conventional-laparoscopic-appendectomy-a-propensity-matched-analysis
#16
Geun Joo Choi, Hyun Kang, Beom Gyu Kim, Yoo Shin Choi, Jin Yun Kim, Sangseok Lee
BACKGROUND: The aim of this study was to compare postoperative pain outcomes between single-incision laparoscopic appendectomy (SILA) and conventional laparoscopic appendectomy (CLA) using a propensity score matching analysis. MATERIALS AND METHODS: Adult patients who underwent SILA or CLA for acute appendicitis between January 2010 and December 2015 at a single center were identified retrospectively from a prospectively collected database. All patients had used an intravenous patient-controlled analgesia (PCA) device for postoperative pain control...
May 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28547181/sequential-feeding-of-lipid-supplement-enriches-beef-adipose-tissues-with-18-3n-3-biohydrogenation-intermediates
#17
P Vahmani, J L Aalhus, D C Rolland, T A McAllister, N Prieto, H C Block, S D Proctor, L L Guan, M E R Dugan
The present study was designed to determine if feeding steers extruded flaxseed and hay (25 and 75%; DM basis) together as a total mixed ration (TMR), or sequentially (non-TMR) would result in different enrichments of polyunsaturated fatty acids (PUFA) and their biohydrogenation intermediates (BHI) in beef adipose tissues [subcutaneous (SC) vs perirenal (PR) fat]. Forty-eight Angus cross steers (325 ± 16 kg) were stratified by weight to six pens, and pens were randomized to either TMR or non-TMR and fed ad libitum for an average of 242 days...
May 25, 2017: Lipids
https://www.readbyqxmd.com/read/28523042/effect-of-conjugated-linoleic-acid-supplementation-on-quality-of-life-in-rectal-cancer-patients-undergoing-preoperative-chemoradiotherapy
#18
Elnaz Faramarzi, Reza Mahdavi, Mohammad Mohammad-Zadeh, Behnam Nasirimotlagh, Sarvin Sanaie
OBJECTIVES: This study set out with the aim of evaluating the effect of conjugated linoleic acid (CLA) supplementation on quality of life in rectal cancer patients undergoing to preoperative chemoradiotherapy. METHODS: In this study, 33 volunteer patients with rectal cancer treated with preoperative chemoradiotherapy were allocated in the CLA (n=16) and the placebo groups (n=17). The CLA group and placebo groups received 3 gr CLA/d and 4 placebo capsules for 6 weeks respectively...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28516859/recombinant-esterase-from-corynebacterium-pseudotuberculosis-in-dna-and-subunit-recombinant-vaccines-partially-protects-mice-against-challenge
#19
Alexandre Antunes Brum, Andrea de Fatima Silva Rezende, Francisco Silvestre Brilhante, Thais Collares, Karine Begnine, Fabiana Kommling Seixas, Tiago Veiras Collares, Odir Antônio Dellagostin, Vasco Azevedo, Anderson Santos, Ricardo Wagner Portela, Sibele Borsuk
PURPOSE: We tested the efficacy of the esterase encoded by cp1002_RS09720 from Corynebacteriumpseudotuberculosis in recombinant subunit and DNA caseous lymphadenitis (CLA) vaccines. This target was predicted as one of the best CLA vaccine candidates by mature epitope density analysis. METHODOLOGY: Gene cp1002_RS09720 was cloned into two different vectors (pAE for subunit vaccine and pTARGET for DNA vaccine). Four groups of 15 mice each were immunized with the recombinant esterase rCP09720 associated with aluminium hydroxide adjuvant (G1), pTARGET/cp09720 DNA vaccine (G2), a naked pTARGET (G3) or PBS as a negative control (G4)...
May 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28515219/a-novel-stool-pcr-test-for-helicobacter-pylori-may-predict-clarithromycin-resistance-and-patient-eradication-at-a-high-rate
#20
Erin Beckman, Ilaria Saracino, Giulia Fiorini, Courtney Clark, Vladimir Slepnev, Denise Patel, Clarissa Gomez, Reddy Ponaka, Vecheslav Elagin, Dino Vaira
Objectives: Clarithromycin-based regimens are commonly used as a first line therapy in H. pylori positive patients, however treatment failures are associated with resistance to clarithromycin. The aim of this study was to evaluate the feasibility of using stool samples to detect the presence of H. pylori DNA, while concurrently detecting mutations associated with the resistance to clarithromycin.Methods: Total DNA was extracted from 294 raw stools of H pylori positive and negative patients. TaqMan real-time PCR amplification was used to detect the presence of H...
May 17, 2017: Journal of Clinical Microbiology
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