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https://www.readbyqxmd.com/read/29786870/the-association-between-local-atherosclerosis-of-the-prostatic-artery-and-benign-prostatic-enlargement-in-humans-putative-mechanism-of-chronic-ischemia-for-prostatic-enlargement
#1
Nobuhiro Haga, Hidenori Akaihata, Junya Hata, Ken Aikawa, Tomohiko Yanagida, Kanako Matsuoka, Tomoyuki Koguchi, Seiji Hoshi, Soichiro Ogawa, Masao Kataoka, Yuichi Sato, Kei Ishibashi, Osamu Suzuki, Yuko Hashimoto, Yoshiyuki Kojima
BACKGROUND: To investigate the possible pathogenesis of the benign prostatic enlargement (BPE) induced by local atherosclerosis, the association between local atherosclerosis and prostatic enlargement was investigated, and molecular biological analyses were performed using human prostatectomy specimens. METHODS: A total of 69 consecutive patients who underwent robot-assisted radical prostatectomy (RARP) participated in this prospective study. To evaluate actual local atherosclerosis, prostatic arteries were removed during RARP...
May 21, 2018: Prostate
https://www.readbyqxmd.com/read/29786867/growth-hormone-releasing-hormone-antagonists-reduce-prostatic-enlargement-and-inflammation-in-carrageenan-induced-chronic-prostatitis
#2
Petra Popovics, Renzhi Cai, Wei Sha, Ferenc G Rick, Andrew V Schally
BACKGROUND: Inflammation plays a key role in the etiology of benign prostatic hyperplasia (BPH) through multiple pathways involving the stimulation of proliferation by cytokines and growth factors as well as the induction of the focal occurrence of epithelial-to-mesenchymal transition (EMT). We have previously reported that GHRH acts as a prostatic growth factor in experimental BPH and in autoimmune prostatitis models and its blockade with GHRH antagonists offer therapeutic approaches for these conditions...
May 21, 2018: Prostate
https://www.readbyqxmd.com/read/29786713/in-situ-fabrication-of-hollow-zno-nc-polyhedra-from-zif-8-for-the-determination-of-trace-cd-ii
#3
Xueping Zhang, Qingqing Wang, Jing Li, Liang Huang, Dengbin Yu, Shaojun Dong
In this work, a novel electrochemical sensor for Cd(ii) detection with differential pulse anodic stripping voltammetry (DPASV) is fabricated based on hollow ZnO@nitrogen-doped carbon (H-ZnO@NC) polyhedra, which are prepared from ZIF-8 via in situ tannic acid etching and a subsequent calcination process. The as-obtained H-ZnO@NC exhibits a polyhedral morphology with a well-defined hollow structure and a uniform distribution of elements C, N, O, and Zn in the shell. The unique structure of H-ZnO@NC can provide an enlarged surface area and abundant active sites...
May 22, 2018: Analyst
https://www.readbyqxmd.com/read/29786701/lutembacher-syndrome-with-mitral-valve-calcification-in-a-31-year-old-male
#4
Arsalan Majeed Adam, Ansab Godil, Muhammad Saad Ali Mallick, Fahad Khan, Ather Hasan Rizvi, Inam-Ul-Haq Muhammad Makhdoom
Lutembacher syndrome is characterized by a congenital ostium secundum atrial septal defect and an acquired mitral valve stenosis. We present a similar case in a 31-year old male who came in with orthopnoea, central cyanosis and pedal oedema. Examination revealed cardiac murmurs in tricuspid and apical regions. Chest x-ray showed signs of pulmonary congestion and ventricular enlargement. Electrocardiogaphy (ECG) revealed right axis deviation and right bundle branch block along with atrial fibrillation and Transthoracic Echocardiography (TTE) showed abnormal valves (mitral stenosis with calcification and tricuspid regurgitation) and dilated cardiac chambers...
February 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29786588/-infectious-complications-of-prostate-biopsy
#5
Marcin Łykowski, Bartosz Dybowski, Sławomir Poletajew, Tomasz Piecha, Piotr Radziszewski
Prostate cancer is the second most common malignancy in men in Poland. Prostate biopsy remains the gold standard for diagnosis. Every year, the number of procedures is increasing, so knowledge of possible complications is becoming crucial. Over time, a continuous increase in infectious complications of prostate biopsy is observed, so it is important to identify risk factors and preventive methods. Antibiotic prophylaxis is mandatory for prostate biopsy. Simultaneously, complications after prostate biopsy affect as many as 90% of patients, including up to 17% of infective complications...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786576/the-histological-and-electron-microscopic-study-of-the-parotid-salivary-gland-in-dehydrated-rats-of-different-ages
#6
Denys P Biletskyy, Oleg A Ustiansky, Olena S Maksymova, Pavel A Moskalenko, Alexey A Tymoshenko, Anna S Degtyarenko, Viktoriia Yu Harbuzova, Yevhen I Dubovyk, Andrii P Voznyi, Gennadii F Tkach
OBJECTIVE: Introduction: Water-salt metabolism disorders is one of the main factor of salivary gland pathology development. The aim: To study the morphological structure of the parotid salivary gland of young, mature and old rats at micro- and ultrastructural levels under water deprivation. PATIENTS AND METHODS: Materials and methods: The experiment was carried out on thirty six laboratory male rats of different ages (young, mature and old). The rats of the control group received normal volume of drinking water...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786465/trunk-stability-enabled-by-non-invasive-spinal-electrical-stimulation-after-spinal-cord-injury
#7
Mrinal Rath, Albert H Vette, Shyamsundar Ramasubramaniam, Kun Li, Joel Burdick, Victor Reggie Edgerton, Yury Gerasimenko, Dimitry Sayenko
Electrical neuromodulation of spinal networks improves the control of movement of the paralyzed limbs after spinal cord injury (SCI). However, the potential of non-invasive spinal stimulation to facilitate postural trunk control during sitting in humans with SCI has not been investigated. We hypothesized that transcutaneous electrical stimulation of the lumbosacral enlargement can improve trunk posture. Eight participants with non-progressive SCI, C3-T9, AIS A or C, performed different motor tasks during sitting...
May 22, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29785959/common-carotid-artery-diameter-and-risk-of-cardiovascular-events-and-mortality-pooled-analyses-of-four-cohort-studies
#8
Sanaz Sedaghat, Thomas T van Sloten, Stéphane Laurent, Gérard M London, Bruno Pannier, Maryam Kavousi, Francesco Mattace-Raso, Oscar H Franco, Pierre Boutouyrie, M Arfan Ikram, Coen D A Stehouwer
Carotid arterial diameter enlargement is a manifestation of arterial remodeling and may be a risk factor for cardiovascular disease (CVD). We evaluated the association between carotid artery diameter and risk of stroke, coronary heart disease, CVD, and all-cause mortality and explored whether the associations could be explained by processes involved in arterial remodeling, that is, blood pressure-related media thickening, arterial stiffness, arterial wall stress, and atherosclerosis. We included 4887 participants (mean age 67±9 years; 54% women) from 4 cohort studies: Rotterdam Study, NEPHROTEST, Hoorn Study, and a study by Blacher et al...
May 21, 2018: Hypertension
https://www.readbyqxmd.com/read/29785317/a-rare-case-of-penile-metastases-as-a-harbinger-of-primary-pulmonary-adenosquamous-carcinoma
#9
Partha Hota, Tejas N Patel, Xiaofeng Zhao, Carrie Schneider, Omar Agosto
Although lung cancer has a high propensity for distant metastatic disease, penile metastases from primary lung neoplasms are considered particularly rare. A 71-year-old male presented to our hospital with a rapidly enlarging hard palpable penile mass. MR imaging demonstrated two penile masses centered in the left and right corpus cavernosa. Subsequent CT imaging revealed a spiculated pulmonary mass in the right upper lobe with PET/CT, MRI, and surgical exploration, demonstrating evidence of metastases to the left adrenal gland, right subscapularis muscle, brain, and small bowel...
2018: Case Reports in Radiology
https://www.readbyqxmd.com/read/29784961/sarcodon-imbricatus-polysaccharides-improve-mouse-hematopoietic-function-after-cyclophosphamide-induced-damage-via-g-csf-mediated-jak2-stat3-pathway
#10
Xue Wang, Qiubo Chu, Xue Jiang, Yue Yu, Libian Wang, Yaqi Cui, Jiahui Lu, Lirong Teng, Di Wang
Sarcodon imbricatus, a rare medicinal and edible fungus, has various pharmacological bioactivities. We investigated the effects of S. imbricatus polysaccharides (SIPS) on hematopoietic function and identified the underlying mechanisms using in vitro experiments with CHRF, K562, and bone marrow mononuclear cells (BMMNCs) and in vivo experiments with a mouse model of cyclophosphamide-induced hematopoietic dysfunction. We found that SIPS induced proliferation and differentiation of CHRF and K562 cells and upregulated the expression of hematopoietic-related proteins, including p90 ribosomal S6 kinases (RSK1p90), c-Myc, and ETS transcription factor, in the two cell lines...
May 21, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29784613/cryoglobulinemic-glomerulonephritis-associated-with-nodal-and-renal-infiltration-by-t-cell-lymphoma-of-t-follicular-helper-phenotype-a-case-report
#11
Jennifer Li, Marille Umakanathan, Chow Heok P'ng, Winny Varikatt, Fiona Kwok, Ming-Wei Lin, Mirna Vucak-Dzumhur
We present a unique case of cryoglobulinemic glomerulonephritis associated with nodal and renal infiltration by T-cell lymphoma of T-follicular helper phenotype. The patient presented with transient neurologic symptoms, severe nephritic syndrome with nephrotic-range proteinuria, and acute kidney injury. He had elevated double-stranded DNA levels, low complement levels, detectable cryoglobulin, and detectable immunoglobulin M (IgM) paraprotein. The kidney biopsy showed cryoglobulinemic glomerulonephritis with a membranoproliferative pattern and diffuse interstitial infiltrates on light microscopy; IgM, C3 but weak IgG, C1q, and negative C4d staining on immunofluorescence; and deposits with organized substructures on electron microscopy...
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29784581/how-to-make-a-tongue-cellular-and-molecular-regulation-of-muscle-and-connective-tissue-formation-during-mammalian-tongue-development
#12
REVIEW
Martyn T Cobourne, Sachiko Iseki, Anahid A Birjandi, Hadeel Adel Al-Lami, Christel Thauvin-Robinet, Guilherme M Xavier, Karen J Liu
The vertebrate tongue is a complex muscular organ situated in the oral cavity and involved in multiple functions including mastication, taste sensation, articulation and the maintenance of oral health. Although the gross embryological contributions to tongue formation have been known for many years, it is only relatively recently that the molecular pathways regulating these processes have begun to be discovered. In particular, there is now evidence that the Hedgehog, TGF-Beta, Wnt and Notch signaling pathways all play an important role in mediating appropriate signaling interactions between the epithelial, cranial neural crest and mesodermal cell populations that are required to form the tongue...
May 18, 2018: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/29784462/promoting-porcelain-zirconia-bonding-using-different-atmospheric-pressure-gas-plasmas
#13
Yi-Chuan Liu, Jung-Pei Hsieh, Yung-Chung Chen, Li-Li Kang, Chii-Shyang Hwang, Shu-Fen Chuang
OBJECTIVES: To evaluate the effects of different atmospheric-pressure plasma (APP) on the physicochemical properties of yttria-stabilized zirconia, and promoting the adhesion of veneering porcelain. METHODS: Cercon base zirconia disks were prepared to receive different treatments: as-polished, three APPs (oxygen, OP; argon, AP; and CF4 , CP), and grit-blasted (GB). Their surface roughness and hydrophilicity were measured, and surface morphology was examined either after treatments, after simulated porcelain firing, or additional thermal etching...
May 18, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29784024/successful-resection-of-a-slow-growing-synchronous-pulmonary-metastasis-from-distal-cholangiocarcinoma-resected-3-5-years-after-initial-surgery-a-case-report
#14
Teruhisa Sakamoto, Soichiro Honjo, Masaki Morimoto, Masataka Amisaki, Yosuke Arai, Naruo Tokuyasu, Keigo Ashida, Hiroaki Saito, Kanae Nosaka, Yoshiyuki Fujiwara
BACKGROUND: A few reports have described the effectiveness of resection for recurrent cholangiocarcinoma. However, none have described resection of synchronous pulmonary metastasis from distal cholangiocarcinoma. We report the first case, to the best of our knowledge, of a slow-growing synchronous pulmonary metastasis from distal cholangiocarcinoma resected 3.5 years after the initial surgery. CASE PRESENTATION: A 67-year-old Japanese man with a diagnosis of distal cholangiocarcinoma was referred to our hospital...
May 22, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29783986/impact-of-the-cone-operation-on-left-ventricular-size-function-and-dyssynchrony-in-ebstein-anomaly-a-cardiovascular-magnetic-resonance-study
#15
Rebecca S Beroukhim, Linyuan Jing, David M Harrild, Brandon K Fornwalt, Abba Mejia-Spiegeler, Jonathan Rhodes, Sitaram Emani, Andrew J Powell
BACKGROUND: In addition to tricuspid regurgitation (TR) and right ventricular (RV) enlargement, patients with Ebstein anomaly are at risk for left ventricular (LV) dysfunction and dyssynchrony. We studied the impact of the cone tricuspid valve reconstruction operation on LV size, function, and dyssynchrony. METHODS: All Ebstein anomaly patients who had both pre- and postoperative cardiovascular magnetic resonance (CMR) studies were retrospectively identified. From cine images, RV and LV volumes and ejection fractions (EF) were calculated, and LV circumferential and longitudinal strain were measured by feature tracking...
May 21, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29783914/early-application-of-an-intermittent-pneumatic-compression-device-is-safe-and-results-in-proximal-arteriovenous-fistula-enlargement
#16
Sanjay Desai, Amit Mitra, Ed Arkans, Tej M Singh
INTRODUCTION: Delays in arteriovenous fistula maturation can cause care delays and increased costs. Increased distention pressure and intermittent wall shear stress may dilate veins based on prior research. Early use of non-invasive devices may help assist clinical arteriovenous fistula dilation. METHODS: This was an Institutional Review Board approved study. After arteriovenous fistula creation, a novel, intermittent pneumatic compression device (Fist Assist® ) was applied 15 cm proximal to arteriovenous fistula enabling 60 mmHg of cyclic compression for 6 h daily for 30 days...
May 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29783802/-clinicopathologic-and-molecular-features-of-cribriform-morular-variant-of-papillary-thyroid-carcinoma
#17
X J Cui, H O Zhao, P Su, J Chen, R Y Zhang, Y Pan, X M Ouyang, J Liu, J Q Zhang, Y Yang, R Yang, L Ding, Z Y Liu
Objective: To investigate the clinicopathologic and molecular features of the rare cribriform morular variant of papillary thyroid carcinoma (CMV-PTC). Methods: The clinicopathologic data of 10 patients with CMV-PTC were retrospectively reviewed. Immunohistochemical (IHC) staining was done using LSAB method. DNA sequencing for APC were applied using Sanger method. BRAF V600E mutation was examined using ARMS method. The cytological, morphological, IHC and molecular features were analyzed. Results: All patients were female at an average age of 27 years old...
May 8, 2018: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29783547/re-predictors-of-successful-trial-without-catheter-following-acute-urinary-retention-in-benign-prostatic-enlargement-a-single-centre-multivariate-analysis
#18
https://www.readbyqxmd.com/read/29783546/re-benign-prostatic-obstruction-relief-in-patients-with-lower-urinary-tract-symptoms-suggestive-of-benign-prostatic-enlargement-undergoing-endoscopic-surgical-procedures-or-therapy-with-alpha-blockers-a-review-of-urodynamic-studies
#19
https://www.readbyqxmd.com/read/29783001/laparoscopic-extraperitoneal-pelvic-lymph-node-debulking-in-locally-advanced-cervical-cancer
#20
Diaz-Feijoo Berta, Luna-Guibourg Rocio, Cabrera Silvia, Manrique Susana, Gil-Moreno Antonio
OBJECTIVE: To demonstrate the feasibility of laparoscopic extraperitoneal approach for pelvic metastatic lymph node debulking in locally advanced cervical cancer. DESIGN: Surgical video article. Canadian task force Classification III. SETTING: University Hospital PATIENT: A 52 year-old patient presented a stage IIA2 Cervical adenocarcinoma according to FIGO classification. The physical exam reported a 45 mm tumor. Positron emission tomography (PET- CT) was positive for hypermetabolic enlarged lymph nodes in left external iliac region of 1...
May 18, 2018: Journal of Minimally Invasive Gynecology
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