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https://www.readbyqxmd.com/read/29149787/the-role-of-the-home-environment-in-dementia-care-and-support-systematic-review-of-qualitative-research
#1
Dia Soilemezi, Amy Drahota, John Crossland, Rebecca Stores
Background The domestic home is the preferred site for care provision for people with dementia and their families, therefore creating a dementia and caring friendly home environment is crucial. This systematic review synthesised qualitative studies to explore the role of the home environment and identify potential barriers and facilitators in home dementia care and support to inform future practice and research. Methods A systematic search in 12 databases identified international qualitative literature on perceptions and experiences of community-dwelling people with dementia, family and formal carers regarding the role of the home environment and ways to tackle daily challenges...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29148566/factors-that-influence-the-provision-of-intrapartum-and-postnatal-care-by-skilled-birth-attendants-in-low-and-middle-income-countries-a-qualitative-evidence-synthesis
#2
REVIEW
Susan Munabi-Babigumira, Claire Glenton, Simon Lewin, Atle Fretheim, Harriet Nabudere
BACKGROUND: In many low- and middle-income countries women are encouraged to give birth in clinics and hospitals so that they can receive care from skilled birth attendants. A skilled birth attendant (SBA) is a health worker such as a midwife, doctor, or nurse who is trained to manage normal pregnancy and childbirth. (S)he is also trained to identify, manage, and refer any health problems that arise for mother and baby. The skills, attitudes and behaviour of SBAs, and the extent to which they work in an enabling working environment, impact on the quality of care provided...
November 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29148432/a-singular-value-decomposition-linear-programming-svdlp-optimization-technique-for-circular-cone-based-robotic-radiotherapy
#3
Bin Liang, Yongbao Li, Wei Ran, Bin Guo, Xuang Xu, Bo Liu, Jiafeng Li, Qiuwen Wu, Fugen Zhou
With robot-controlled linac positioning, the robotic radiotherapy system such as CyberKnife significantly increases the freedom in radiation beam placement, but also imposes more challenges on treatment plan optimization. The resampling mechanism in vendor supplied treatment planning system (MultiPlan) could not fully explore the increased beam direction search space. Besides, a sparse treatment plan (using fewer beams) is desired to improve the treatment efficiency. This study proposes a singular value decomposition linear programming (SVDLP) optimization technique for circular collimator based robotic radiotherapy...
November 17, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29147143/analyzing-text-recognition-from-tactually-evoked-eeg
#4
A Khasnobish, S Datta, R Bose, D N Tibarewala, A Konar
Tactual exploration of objects produce specific patterns in the human brain and hence objects can be recognized by analyzing brain signals during tactile exploration. The present work aims at analyzing EEG signals online for recognition of embossed texts by tactual exploration. EEG signals are acquired from the parietal region over the somatosensory cortex of blindfolded healthy subjects while they tactually explored embossed texts, including symbols, numbers, and alphabets. Classifiers based on the principle of supervised learning are trained on the extracted EEG feature space, comprising three features, namely, adaptive autoregressive parameters, Hurst exponents, and power spectral density, to recognize the respective texts...
December 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29143503/-lung-and-pleural-space-ultrasonography-for-pulmonologist
#5
Leslie Noirez, Laurent P Nicod
In the past twenty years ultrasound has been the subject of renewed interest in lung exploration in the broad sense. The necessity of accessing a means of rapid exploration at the bed of the patient in a critical situation has led to the development of a pleuro-pulmonary ultrasound semiology to make it a diagnostic tool of choice which exceeds the strict framework intensive care units and emergency services. With the diagnosis of thoracic tumors or the exploration of interstitial syndromes, it tends to integrate more into the daily practice of the pulmonologist...
November 15, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29143383/who-performs-colonoscopy-workforce-trends-over-space-and-time
#6
Jan M Eberth, Michele J Josey, Lee R Mobley, Davidson O Nicholas, Donna B Jeffe, Cassie Odahowski, Janice C Probst, Mario Schootman
PURPOSE: With the increased availability of colonoscopy to average risk persons due to insurance coverage benefit changes, we sought to identify changes in the colonoscopy workforce. We used outpatient discharge records from South Carolina between 2001 and 2010 to examine shifts over time and in urban versus rural areas in the types of medical providers who perform colonoscopy, and the practice settings in which they occur, and to explore variation in colonoscopy volume across facility and provider types...
November 16, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/29142324/an-algorithm-for-the-beat-to-beat-assessment-of-cardiac-mechanics-during-sleep-on-earth-and-in-microgravity-from-the-seismocardiogram
#7
Marco Di Rienzo, Emanuele Vaini, Prospero Lombardi
Seismocardiogram, SCG, is the measure of precordial vibrations produced by the beating heart, from which cardiac mechanics may be explored on a beat-to-beat basis. We recently collected a large amount of SCG data (>69 recording hours) from an astronaut to investigate cardiac mechanics during sleep aboard the International Space Station and on Earth. SCG sleep recordings are characterized by a prolonged duration and wide heart rate swings, thus a specific algorithm was developed for their analysis. In this article we describe the new algorithm and its performance...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29140346/performance-evaluation-of-underwater-optical-communications-using-spatial-modes-subjected-to-bubbles-and-obstructions
#8
Yifan Zhao, Andong Wang, Long Zhu, Weichao Lv, Jing Xu, Shuhui Li, Jian Wang
Spatial modes have attracted increasing interest in free-space and fiber-based optical communications. Underwater wireless optical communication is becoming a promising technique in marine exploration. Here we investigate the underwater wireless optical communications using different spatial modes, i.e., traditional Gaussian modes, orbital angular momentum modes having helical phase fronts, and diffraction-free and obstruction-tolerant Bessel modes. We evaluate the underwater transmission performance of three spatial modes subjected to dynamic bubbles, which cause similar power fluctuations, regardless of spatial modes...
November 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29138413/oscillators-that-sync-and-swarm
#9
Kevin P O'Keeffe, Hyunsuk Hong, Steven H Strogatz
Synchronization occurs in many natural and technological systems, from cardiac pacemaker cells to coupled lasers. In the synchronized state, the individual cells or lasers coordinate the timing of their oscillations, but they do not move through space. A complementary form of self-organization occurs among swarming insects, flocking birds, or schooling fish; now the individuals move through space, but without conspicuously altering their internal states. Here we explore systems in which both synchronization and swarming occur together...
November 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/29136658/community-ecology-in-3d-tensor-decomposition-reveals-spatio-temporal-dynamics-of-large-ecological-communities
#10
Romain Frelat, Martin Lindegren, Tim Spaanheden Denker, Jens Floeter, Heino O Fock, Camilla Sguotti, Moritz Stäbler, Saskia A Otto, Christian Möllmann
Understanding spatio-temporal dynamics of biotic communities containing large numbers of species is crucial to guide ecosystem management and conservation efforts. However, traditional approaches usually focus on studying community dynamics either in space or in time, often failing to fully account for interlinked spatio-temporal changes. In this study, we demonstrate and promote the use of tensor decomposition for disentangling spatio-temporal community dynamics in long-term monitoring data. Tensor decomposition builds on traditional multivariate statistics (e...
2017: PloS One
https://www.readbyqxmd.com/read/29136638/a-free-boundary-model-of-a-motile-cell-explains-turning-behavior
#11
Masoud Nickaeen, Igor L Novak, Stephanie Pulford, Aaron Rumack, Jamie Brandon, Boris M Slepchenko, Alex Mogilner
To understand shapes and movements of cells undergoing lamellipodial motility, we systematically explore minimal free-boundary models of actin-myosin contractility consisting of the force-balance and myosin transport equations. The models account for isotropic contraction proportional to myosin density, viscous stresses in the actin network, and constant-strength viscous-like adhesion. The contraction generates a spatially graded centripetal actin flow, which in turn reinforces the contraction via myosin redistribution and causes retraction of the lamellipodial boundary...
November 14, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29136521/toward-dynamic-urban-environmental-exposure-assessments-in-mental-health-research
#12
Marco Helbich
It is increasingly recognized that mental disorders are affected by both personal characteristics and environmental exposures. The built, natural, and social environments can either contribute to or buffer against metal disorders. Environmental exposure assessments related to mental health typically rely on neighborhoods within which people currently live. In this article, I call into question such neighborhood-based exposure assessments at one point in time, because human life unfolds over space and across time...
November 11, 2017: Environmental Research
https://www.readbyqxmd.com/read/29134826/cancer-patients-recommendations-for-nature-based-design-and-engagement-in-oncology-contexts-qualitative-research
#13
Sarah Blaschke, Clare C O'Callaghan, Penelope Schofield
OBJECTIVES: To explore cancer patients' recommendations for nature engagement based on their subjective nature experiences and observations in the cancer setting. The rationale was to gain practical insight for delineating relevant and translatable nature-based care and design opportunities in oncology contexts. BACKGROUND: Innovative cancer care services are needed to respond to growing demand and shifting healthcare needs. Engagement with nature has shown multiple health benefits and presents a promising opportunity for application in healthcare to improve outcomes...
January 1, 2017: HERD
https://www.readbyqxmd.com/read/29134766/comparative-analyses-of-data-independent-acquisition-mass-spectrometric-approaches-dia-wisim-dia-and-untargeted-dia
#14
Frank Koopmans, Jenny T C Ho, August B Smit, Ka Wan Li
Data independent acquisition (DIA) is an emerging technology for quantitative proteomics. Current DIA focusses on the identification and quantitation of fragment ions that are generated from multiple peptides contained in the same selection-window of several to tens of m/z. An alternative approach is WiSIM-DIA, which combines conventional DIA with wide-SIM (wide-selected ion monitoring) windows to partition the precursor m/z space to produce high quality precursor ion chromatograms. However WiSIM-DIA has been under-explored; it remains unclear if it is a viable alternative to DIA...
November 14, 2017: Proteomics
https://www.readbyqxmd.com/read/29134681/gravity-constraints-drive-biological-systems-toward-specific-organization-patterns-commitment-of-cell-specification-is-constrained-by-physical-cues
#15
REVIEW
Mariano Bizzarri, Maria Grazia Masiello, Alessandro Giuliani, Alessandra Cucina
Different cell lineages growing in microgravity undergo a spontaneous transition leading to the emergence of two distinct phenotypes. By returning these populations in a normal gravitational field, the two phenotypes collapse, recovering their original configuration. In this review, we hypothesize that, once the gravitational constraint is removed, the system freely explores its phenotypic space, while, when in a gravitational field, cells are "constrained" to adopt only one favored configuration. We suggest that the genome allows for a wide range of "possibilities" but it is unable per se to choose among them: the emergence of a specific phenotype is enabled by physical constraints that drive the system toward a preferred solution...
November 14, 2017: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
https://www.readbyqxmd.com/read/29134470/the-effect-of-long-term-confinement-and-the-efficacy-of-exercise-countermeasures-on-muscle-strength-during-a-simulated-mission-to-mars-data-from-the-mars500-study
#16
Christopher J Gaffney, Elena Fomina, Dennis Babich, Vladimir Kitov, Konstantin Uskov, David A Green
BACKGROUND: Isolation and long duration spaceflight are associated with musculoskeletal deconditioning. Mars500 was a unique, high-fidelity analogue of the psychological challenges of a 520-day manned mission to Mars. We aimed to explore the effect of musculoskeletal deconditioning on three outcome measures: (1) if lower limb muscle strength was reduced during the 520-day isolation; (2) if type I or II muscle fibres were differentially affected; and (3) whether any 70-day exercise interventions prevented any isolation-induced loss of strength...
November 13, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/29133927/random-protein-sequences-can-form-defined-secondary-structures-and-are-well-tolerated-in-vivo
#17
Vyacheslav Tretyachenko, Jiří Vymětal, Lucie Bednárová, Vladimír Kopecký, Kateřina Hofbauerová, Helena Jindrová, Martin Hubálek, Radko Souček, Jan Konvalinka, Jiří Vondrášek, Klára Hlouchová
The protein sequences found in nature represent a tiny fraction of the potential sequences that could be constructed from the 20-amino-acid alphabet. To help define the properties that shaped proteins to stand out from the space of possible alternatives, we conducted a systematic computational and experimental exploration of random (unevolved) sequences in comparison with biological proteins. In our study, combinations of secondary structure, disorder, and aggregation predictions are accompanied by experimental characterization of selected proteins...
November 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29133452/an-intermediate-level-of-abstraction-for-computational-systems-chemistry
#18
Jakob L Andersen, Christoph Flamm, Daniel Merkle, Peter F Stadler
Computational techniques are required for narrowing down the vast space of possibilities to plausible prebiotic scenarios, because precise information on the molecular composition, the dominant reaction chemistry and the conditions for that era are scarce. The exploration of large chemical reaction networks is a central aspect in this endeavour. While quantum chemical methods can accurately predict the structures and reactivities of small molecules, they are not efficient enough to cope with large-scale reaction systems...
December 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/29133444/exploring-astrobiology-using-in-silico-molecular-structure-generation
#19
REVIEW
Markus Meringer, H James Cleaves
The origin of life is typically understood as a transition from inanimate or disorganized matter to self-organized, 'animate' matter. This transition probably took place largely in the context of organic compounds, and most approaches, to date, have focused on using the organic chemical composition of modern organisms as the main guide for understanding this process. However, it has gradually come to be appreciated that biochemistry, as we know it, occupies a minute volume of the possible organic 'chemical space'...
December 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/29132291/hiv-prevention-needs-for-men-who-have-sex-with-men-in-swaziland
#20
Bhekie Sithole
Men who have sex with men (MSM) have a high HIV burden and also often face multiple other challenges accessing HIV services, including legal and social issues. Although Swaziland recently started responding with interventions for MSM, significant gaps still exist both in information and programming. This study aimed to explore the HIV prevention needs of MSM in Swaziland, including factors elevating their risks and vulnerabilities to HIV infection; to find out what HIV prevention strategies exist; and to determine how best to meet the prevention needs of MSM...
December 2017: African Journal of AIDS Research: AJAR
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