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https://www.readbyqxmd.com/read/28110044/dopaminergic-modulation-of-multi-muscle-synergies-in-postural-tasks-performed-by-patients-with-parkinson-s-disease
#1
Ali Falaki, Xuemei Huang, Mechelle M Lewis, Mark L Latash
BACKGROUND: Postural instability is one of most disabling motor symptoms in Parkinson's disease. Indices of multi-muscle synergies are new measurements of postural stability. OBJECTIVES: We explored the effects of dopamine-replacement drugs on multi-muscle synergies stabilizing center of pressure coordinate and their adjustments prior to a self-triggered perturbation in patients with Parkinson's disease. We hypothesized that both synergy indices and synergy adjustments would be improved on dopaminergic drugs...
January 11, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28109241/the-chemical-space-of-pbn-nbin-and-pbn-nbin-a-systematic-study-for-n-3-13
#2
Christian Seifried, Lilla Longo, Patrik Pollak, Florian Weigend
A systematic exploration of the energy hypersurfaces of three to 13-atomic neutral and cationic binary lead-bismuth clusters is presented. Global minima for all 99 compositions (N = 3-13, n = 0-N) were obtained by a density functional theory based genetic algorithm, which was applied to every single composition, both for the neutral clusters and for the cations. Within the genetic algorithm, the energetically most favorable assignment of atom types to atom positions was found via aimed swapping of element types, based on first-order perturbation theory in the nuclear charge...
January 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28109103/-value-of-diffusion-weighted-imaging-1-h-magnetic-resonance-spectroscopy-and-3d-whole-brain-arterial-spin-labeling-in-the-diagnosis-of-medulloblastoma
#3
Dong-Liang Cheng, Wen-Sheng Wang, Yi-Xin Hu, Meng-Lin Chen, Ge Wen, Li-Na Cheng, Jing Wu, Liu-Qing Yan
OBJECTIVE: To explore the value of diffusion-weighted imaging (DWI), (1)H-magnetic resonance spectroscopy (1H-MRS) and 3D whole-brain arterial spin labeling (3D ASL) in the diagnosis of medulloblastoma in the posterior cranial fossa. METHODS: The magnetic resonance imaging (MRI) findings of 16 patients with pathologically confirmed medulloblastoma in the posterior cranial fossa were analyzed retrospectively. All the patients were examined with plane and enhanced brain MRI scans; 5 patients also underwent examinations with DWI, 12 with MRS, and 5 with 3D ASL...
January 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28108623/tumor-induced-stromal-stat1-accelerates-breast-cancer-via-deregulating-tissue-homeostasis
#4
Victoria R Zellmer, Patricia M Schnepp, Sarah L Fracci, Xuejuan Tan, Erin N Howe, Siyuan Zhang
: The tumor microenvironment (TME) is a dynamic tissue space in which the tumor exists, plays a significant role in tumor initiation, and is a key contributor in cancer progression; however, little is known about tumor-induced changes in the adjacent tissue stroma. Herein, tumor-induced changes in the TME were explored at the morphological and molecular level to further understand cancer progression. Tumor-adjacent mammary glands (TAGs) displayed altered branching morphology, expansion of myofibroblasts, and increased mammosphere formation, broadly suggesting a tumor-induced field effect...
January 20, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/28107843/staff-perspectives-regarding-the-implementation-of-a-yoga-intervention-with-chronic-pain-self-management-in-a-clinical-setting
#5
Emily A Waddington, Reid K Rogers Fuller, Rachel C K Barloon, Grace H Comiskey, Jennifer Dickman Portz, Helen Holmquist-Johnson, Arlene A Schmid
Chronic pain affects millions of Americans and can be addressed through multiple modalities, interventions, and strategies. Yoga and self-management have been proven effective in treating chronic pain, but little research has been conducted on the feasibility and implementation barriers related to these alternative intervention forms. In our qualitative study, we examined staff perceptions regarding the feasibility of implementing yoga along with established self-management at a pain management clinic in Colorado...
February 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28106460/fermi-large-area-telescope-as-a-galactic-supernovae-axionscope
#6
M Meyer, M Giannotti, A Mirizzi, J Conrad, M A Sánchez-Conde
In a Galactic core-collapse supernova (SN), axionlike particles (ALPs) could be emitted via the Primakoff process and eventually convert into γ rays in the magnetic field of the Milky Way. From a data-driven sensitivity estimate, we find that, for a SN exploding in our Galaxy, the Fermi Large Area Telescope (LAT) would be able to explore the photon-ALP coupling down to g_{aγ}≃2×10^{-13}  GeV^{-1} for an ALP mass m_{a}≲10^{-9}  eV. These values are out of reach of next generation laboratory experiments...
January 6, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28106370/redox-active-cation-intercalation-deintercalation-in-two-dimensional-layered-mno2-nanostructures-for-high-rate-electrochemical-energy-storage
#7
Pan Xiong, Renzhi Ma, Nobuyuki Sakai, Xueyin Bai, Shen Li, Takayoshi Sasaki
Two-dimensional (2D) layered materials with high intercalation pseudocapacitance have long been investigated for Li+-ion-based electrochemical energy storage. By contrast, the exploration of guest ions other than Li+ has been limited, although promising. The present study investigate the intercalation/deintercalation behaviors of various metal ions in 2D layered MnO2 with various interlayer distances, K-birnessite nanobelt (K-MnO2), its protonated form (H-MnO2), and a freeze-dried sample of exfoliated nanosheets...
January 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28105489/whisker-touch-guides-canopy-exploration-in-a-nocturnal-arboreal-rodent-the-hazel-dormouse-muscardinus-avellanarius
#8
Kendra Arkley, Guuske P Tiktak, Vicki Breakell, Tony J Prescott, Robyn A Grant
Dormouse numbers are declining in the UK due to habitat loss and fragmentation. We know that dormice are nocturnal, arboreal, and avoid crossing open spaces between habitats, yet how they navigate around their canopy is unknown. As other rodents use whisker touch sensing to navigate and explore their environment, this study investigates whether Hazel dormice (Muscardinus avellanarius) employ their whiskers to cross between habitats. We analysed high-speed video footage of dormice exploring freely in flat and climbing arenas in near darkness and using infrared light illumination...
January 20, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28103665/computational-search-for-novel-hard-chromium-based-materials
#9
Alexander G Kvashnin, Artem R Oganov, Artem I Samtsevich, Zahed Allahyari
Nitrides, carbides and borides of transition metals are an attractive class of hard materials. Our recent preliminary explorations of the binary chemical compounds indicated that chromium-based materials are among the hardest transition metal compounds. Motivated by this, here we explore in detail the binary Cr-B, Cr-C and Cr-N systems using global optimization techniques. Calculated enthalpy of formation and hardness of predicted materials were used for Pareto optimization to define the hardest materials with lowest energy...
January 20, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28103568/on-the-exploration-of-information-from-the-dtw-cost-matrix-for-online-signature-verification
#10
Abhishek Sharma, Suresh Sundaram
This paper explores the utility of information derived from the dynamic time warping (DTW) cost matrix for the problem of online signature verification. The prior works in literature primarily utilize only the DTW scores to authenticate a test signature. To the best of our knowledge, the characteristics of the warping path (used for the alignment) in the cost matrix is hardly exploited for verification of online signatures. Accordingly, we devise a score that utilizes the information from the cost matrix and warping path alignments...
January 17, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28103294/community-based-entomological-surveillance-reveals-urban-foci-of-chagas-disease-vectors-in-sobral-state-of-cear%C3%A3-northeastern-brazil
#11
Cynara Carvalho Parente, Fernando S M Bezerra, Plutarco I Parente, Raimundo V Dias-Neto, Samanta C C Xavier, Alberto N Ramos, Filipe A Carvalho-Costa, Marli M Lima
BACKGROUND: The aim of this work was to explore the potential risk of vector-borne Chagas disease in urban districts in northeastern Brazil, by analyzing the spatiotemporal distributions and natural infection rates with Trypanosoma cruzi of triatomine species captured in recent years. The main motivation of this work was an acute human case of Chagas disease reported in 2008 in the municipality of Sobral. METHODOLOGY/PRINCIPAL FINDINGS: We analyzed data from community-based entomological surveillance carried out from 2010 to 2014...
2017: PloS One
https://www.readbyqxmd.com/read/28102254/rational-design-of-reconfigurable-prismatic-architected-materials
#12
Johannes T B Overvelde, James C Weaver, Chuck Hoberman, Katia Bertoldi
Advances in fabrication technologies are enabling the production of architected materials with unprecedented properties. Most such materials are characterized by a fixed geometry, but in the design of some materials it is possible to incorporate internal mechanisms capable of reconfiguring their spatial architecture, and in this way to enable tunable functionality. Inspired by the structural diversity and foldability of the prismatic geometries that can be constructed using the snapology origami technique, here we introduce a robust design strategy based on space-filling tessellations of polyhedra to create three-dimensional reconfigurable materials comprising a periodic assembly of rigid plates and elastic hinges...
January 18, 2017: Nature
https://www.readbyqxmd.com/read/28102070/well-ordered-oxygen-deficient-comoo4-and-fe2o3-nanoplate-arrays-on-3d-graphene-foam-towards-flexible-asymmetric-supercapacitor-with-enhanced-capacitive-properties
#13
Kai Chi, Zheye Zhang, Qi-Ying Lv, Chuyi Xie, Jian Xiao, Fei Xiao, Shuai Wang
In this work, we report the development of well-ordered hydrogenated CoMoO4 (H-CoMoO4) and hydrogenated Fe2O3 (H-Fe2O3) nanoplate arrays on 3D graphene foam (GF), and explore their practice application as binder-free electrodes in assembling flexible all-solid-state asymmetric supercapacitor (ASC) device. Our results show that the monolithic 3D porous GF prepared by solution casting method using Ni foam template possesses large surface area, superior electrical conductivity, and sufficient surface functional groups, which not only facilitate in situ growth of CoMoO4 and Fe2O3 nanoplates on it, but also contribute the double-layer capacitance of resultant supercapacitor...
January 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28101267/bioart-and-bildung-wetware-art-agency-animation-an-exhibition-as-case-study
#14
Charissa N Terranova
Recent events in the field of biology have further unfixed the definition of life. The negotiability of "life" is at the center of the exhibition "Wetware: Art, Agency, Animation" at the Beall Center for Art + Technology at the University of California, Irvine. The exhibition includes art by nine international artists working in the avant-garde area of contemporary art called "bioart." This article is devoted to the unique educational space opened through the practice of bioart, focusing on how the exhibition brings the scientific question "What is life?" to a public audience...
December 2016: Journal of Microbiology & Biology Education: JMBE
https://www.readbyqxmd.com/read/28100743/three-small-receptive-field-ganglion-cells-in-the-mouse-retina-are-distinctly-tuned-to-size-speed-and-object-motion
#15
Jason Jacoby, Gregory W Schwartz
: Retinal ganglion cells (RGCs) are frequently divided into functional types by their ability to extract and relay specific features from a visual scene, such as the capacity to discern local or global motion, direction of motion, stimulus orientation, contrast or uniformity, or the presence of large or small objects. Here we introduce three previously uncharacterized, nondirection-selective ON-OFF RGC types that represent a distinct set of feature detectors in the mouse retina. The three high-definition (HD) RGCs possess small receptive-field centers and strong surround suppression...
January 18, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28100691/registry-in-a-tube-multiplexed-pools-of-retrievable-parts-for-genetic-design-space-exploration
#16
Lauren B A Woodruff, Thomas E Gorochowski, Nicholas Roehner, Tarjei S Mikkelsen, Douglas Densmore, D Benjamin Gordon, Robert Nicol, Christopher A Voigt
No abstract text is available yet for this article.
January 18, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28098744/trabecular-microstructure-and-damage-affect-cement-leakage-from-the-basivertebral-foramen-during-vertebral-augmentation
#17
Shengyun Li, Chongyan Wang, Zhi Shan, Junhui Liu, Tianming Yu, Xuyang Zhang, Shunwu Fan, Blaine A Christiansen, Wenyuan Ding, Fengdong Zhao
STUDY DESIGN: A prospective study on cadaver specimens. OBJECTIVE: To explore why cement leakage from BF easily occurs during vertebral augmentation procedures. SUMMARY OF BACKGROUND DATA: Type B (through BF, basivertebral foramen) cement leakage is the most common type after vertebral augmentation, but the mechanism of this is still controversial. The contribution of vertebral trabecular bone orientation and trabecular damage during compression fracture to cement leakage is still unknown...
January 16, 2017: Spine
https://www.readbyqxmd.com/read/28097752/social-self-sorting-of-colloidal-families-in-co-assembling-microgel-systems
#18
Kang Han, Dennis Go, Thomas Tigges, Khosrow Rahimi, Alexander J C Kuehne, Andreas Walther
Colloids are valuable model systems to understand the structure and dynamics of matter, explore new self-assembly concepts, and realize advanced materials. Herein, we demonstrate social self-sorting of co-assembled families of colloids by orthogonal host/guest recognition using cyclodextrins. We show that mixtures of four partners self-sort into their respective families without mutual interference. Additionally, the self-assemblies and their interactions are switchable using orthogonal triggers. This study goes beyond previous features of molecular self-sorting, and opens the design space for future self-sorting colloidal systems via rationally designed molecular recognition...
January 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28096733/diagnosis-of-nerve-root-compromise-of-the-lumbar-spine-evaluation-of-the-performance-of-three-dimensional-isotropic-t2-weighted-turbo-spin-echo-space-sequence-at-3t
#19
Jinkyeong Sung, Won-Hee Jee, Joon-Yong Jung, Jinhee Jang, Jin-Sung Kim, Young-Hoon Kim, Kee-Yong Ha
OBJECTIVE: To explore the performance of three-dimensional (3D) isotropic T2-weighted turbo spin-echo (TSE) sampling perfection with application optimized contrasts using different flip angle evolution (SPACE) sequence on a 3T system, for the evaluation of nerve root compromise by disc herniation or stenosis from central to extraforaminal location of the lumbar spine, when used alone or in combination with conventional two-dimensional (2D) TSE sequence. MATERIALS AND METHODS: Thirty-seven patients who had undergone 3T spine MRI including 2D and 3D sequences, and had subsequent spine surgery for nerve root compromise at a total of 39 nerve levels, were analyzed...
January 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28095035/validation-of-a-parametric-finite-element-human-femur-model
#20
Katelyn F Klein, Jingwen Hu, Matthew P Reed, Lawrence W Schneider, Jonathan D Rupp
Objective Finite element (FE) models with geometry and material properties that are parametric with subject descriptors, such as age and body shape/size, are being developed to incorporate population variability into crash simulations. However, the validation methods currently being used with these parametric models do not assess whether model predictions are reasonable in the space over which the model is intended to be used. This study presents a parametric model of the femur and applies a unique validation paradigm to this parametric femur model that characterizes whether model predictions reproduce experimentally observed trends...
January 17, 2017: Traffic Injury Prevention
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