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https://www.readbyqxmd.com/read/28549330/impact-of-post-traumatic-stress-disorder-on-oral-health
#1
Ana Cristina de Oliveira Solis, Álvaro Cabral Araújo, Felipe Corchs, Marcio Bernik, Érica Panzani Duran, Cláudio Silva, Francisco Lotufo-Neto
BACKGROUND: The stress experienced as an intense and traumatic event can increase the odds of orofacial pain, affect the biomechanics of masticatory system and compromise the periodontal health. This study was conducted to investigate the impact of post-traumatic stress disorder (PTSD) on oral health. METHODS: A case-control study with a convenience sample was designed. Probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing, and plaque were recorded at 6 sites per tooth...
May 20, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28549317/frontal-and-subcortical-grey-matter-reductions-in-ptsd
#2
Daniel C M O'Doherty, Ashleigh Tickell, Will Ryder, Charles Chan, Daniel F Hermens, Maxwell R Bennett, Jim Lagopoulos
Post-traumatic stress disorder (PTSD) is characterised by a range of debilitating psychological, physical and cognitive symptoms. PTSD has been associated with grey matter atrophy in limbic and frontal cortical brain regions. However, previous studies have reported heterogeneous findings, with grey matter changes observed beyond limbic/frontal areas. Seventy-five adults were recruited from the community, 25 diagnosed with PTSD along with 25 healthy and 25 trauma exposed age and gender matched controls. Participants underwent clinical assessment and magnetic resonance imaging...
May 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28549312/exposure-to-suicide-is-associated-with-increased-risk-for-suicidal-thoughts-and-behaviors-among-national-guard-military-personnel
#3
Craig J Bryan, Julie Cerel, AnnaBelle O Bryan
BACKGROUND: Research suggests that individuals who know someone who died by suicide are at increased risk for posttraumatic stress disorder (PTSD), depression, and recent suicidal thoughts. Studies have not yet investigated the association of suicide exposure with suicide attempts, however, especially among high-risk subgroups of military personnel such as the National Guard. PROCEDURES: An anonymous online survey was completed by 971 military personnel assigned to the National Guard in Utah and Idaho...
May 18, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28549268/modulation-of-hpa-axis-response-to-social-stress-in-schizophrenia-by-childhood-trauma
#4
Claudia Lange, Christian G Huber, Daniela Fröhlich, Stefan Borgwardt, Undine E Lang, Marc Walter
HPA axis functioning plays an important role in the etiology of schizophrenia spectrum disorders (SSD). However, only few studies have examined HPA axis responsivity to psychosocial stress in SSD, and results are heterogeneous. Furthermore, childhood trauma is known to influence psychopathology and treatment outcome in SSD, but studies on the influence of childhood trauma on stress related HPA axis activity are missing. The purpose of this study was to investigate cortisol response to a psychosocial stress challenge in SSD patients, and to examine its association with severity of childhood trauma...
May 20, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28549161/cigarette-smoking-cessation-intervention-for-buprenorphine-treatment-patients
#5
Sharon M Hall, Gary Humfleet, James Gasper, Kevin L Delucchi, David Hersh, Joseph Guydish
Introduction: Patients receiving Medication Assisted Therapy (MAT) for opioid use disorder have high cigarette smoking rates. Cigarette smoking interventions have had limited success. We evaluated an intervention to increase cigarette abstinence rates in patients receiving buprenorphine-assisted therapy. Methods: Cigarette smokers (N=175; 78% male; 69% Caucasian; 20% Hispanic), recruited from a buprenorphine clinic were randomly assigned to either an extended innovative system intervention (E-ISI) or to Standard Treatment Control (STC)...
May 26, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28549077/clinical-criteria-for-subtyping-parkinson-s-disease-biomarkers-and-longitudinal-progression
#6
Seyed-Mohammad Fereshtehnejad, Yashar Zeighami, Alain Dagher, Ronald B Postuma
Parkinson's disease varies widely in clinical manifestations, course of progression and biomarker profiles from person to person. Identification of distinct Parkinson's disease subtypes is of great priority to illuminate underlying pathophysiology, predict progression and develop more efficient personalized care approaches. There is currently no clear way to define and divide subtypes in Parkinson's disease. Using data from the Parkinson's Progression Markers Initiative, we aimed to identify distinct subgroups via cluster analysis of a comprehensive dataset at baseline (i...
May 25, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28549063/food-addiction-and-obesity-unnecessary-medicalization-of-hedonic-overeating
#7
REVIEW
Graham Finlayson
The concept of addiction is loaded with connotations and is often used for its political as much as its medical utility. The scientific case for 'food addiction' as a clinical phenotype currently rests on its association with generic diagnostic criteria for substance-related disorders being applied to everyday foods and eating-related problems. This has fused the concept of obesity with addiction regardless of whether it fits the definition. The hedonic, or reward, system can account for the ingestion of foods and drugs, confirming that they share neural substrates that differentiate liking and wanting...
May 26, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28549061/central-hypothyroidism-a-neglected-thyroid-disorder
#8
REVIEW
Paolo Beck-Peccoz, Giulia Rodari, Claudia Giavoli, Andrea Lania
Central hypothyroidism is a rare and heterogeneous disorder that is characterized by a defect in thyroid hormone secretion in an otherwise normal thyroid gland due to insufficient stimulation by TSH. The disease results from the abnormal function of the pituitary gland, the hypothalamus, or both. Moreover, central hypothyroidism can be isolated or combined with other pituitary hormone deficiencies, which are mostly acquired and are rarely congenital. The clinical manifestations of central hypothyroidism are usually milder than those observed in primary hypothyroidism...
May 26, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28549057/both-antenatal-and-postnatal-inflammation-contribute-information-about-the-risk-of-brain-damage-in-extremely-preterm-newborns
#9
Diana Yanni, Steven Korzeniewski, Elizabeth N Allred, Raina N Fichorova, T Michael O'Shea, Karl Kuban, Olaf Dammann, Alan Leviton
BACKGROUNDPreterm newborns exposed to intrauterine inflammation are at increased risk of neurodevelopmental disorders. We hypothesized that adverse outcomes are more strongly associated with a combination of antenatal and postnatal inflammation than with either of them alone.METHODSWe defined antenatal inflammation as histologic inflammation in the placenta. We measured the concentrations of seven inflammation-related proteins in blood obtained on postnatal days 1, 7, and 14 from 763 infants born before 28 weeks of gestation...
May 26, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28549047/health-related-quality-of-life-and-sleep-disorders-in-patients-with-a-urostomy-is-there-a-relationship
#10
Chie Furukawa, Ikuharu Morioka
PURPOSE: The purpose of this study was to evaluate the relationship between health-related quality of life (HRQOL) and sleep disorders in persons living with a urostomy. DESIGN: A cross-sectional descriptive study. SUBJECTS AND SETTINGS: Eighty-six adults with a urostomy who were cared for in a stoma outpatient clinic of a hospital in Osaka, Japan, for at least 1 month before data collection, and who were attending support group meetings comprised the sample...
May 25, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28548827/dynamic-disorder-and-electronic-structures-of-electron-precise-dianionic-diboranes-insights-from-solid-state-multinuclear-magnetic-resonance-spectroscopy
#11
Y T Angel Wong, Johannes Landmann, Maik Finze, David L Bryce
The J(11B, 11B) coupling constants of various salts of the electron-precise hexacyanodiborane(6) dianion, [B2(CN)6]2-, were obtained using 11B double-quantum filtered (DQF) J-resolved solid-state nuclear magnetic resonance (SSNMR) spectroscopy. Our results show that the magnitude of the DQF J splitting is influenced by both the crystallo-graphic symmetry of the system and the presence of dynamics. The splittings are amplified by a factor of 3 as compared to the corresponding theoretical J coupling constants for cases where 1) there is an absence of dynamics but the boron pairs are crystallographically equivalent, or 2) the boron pairs are crystallographically inequivalent but are rendered magnetically equivalent on the timescale of the experiment due to dynamic disorder, which was identified by 11B and 13C SSNMR experiments...
May 26, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28548710/measurement-of-glycine-in-healthy-and-tumorous-brain-by-triple-refocusing-mrs-at-3%C3%A2-t-in-vivo
#12
Vivek Tiwari, Zhongxu An, Sandeep K Ganji, Jeannie Baxter, Toral R Patel, Edward Pan, Bruce E Mickey, Elizabeth A Maher, Marco C Pinho, Changho Choi
Glycine (Gly) has been implicated in several neurological disorders, including malignant brain tumors. The precise measurement of Gly is challenging largely as a result of the spectral overlap with myo-inositol (mI). We report a new triple-refocusing sequence for the reliable co-detection of Gly and mI at 3 T and for the evaluation of Gly in healthy and tumorous brain. The sequence parameters were optimized with density-matrix simulations and phantom validation. With a total TE of 134 ms, the sequence gave complete suppression of the mI signal between 3...
May 26, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28548579/genetic-variation-of-the-mu-opioid-receptor-oprm1-and-dopamine-d2-receptor-drd2-is-related-to-smoking-differences-in-patients-with-schizophrenia-but-not-bipolar-disorder
#13
Mika Hirasawa-Fujita, Michael J Bly, Vicki L Ellingrod, Gregory W Dalack, Edward F Domino
It is not known why mentally ill persons smoke excessively. Inasmuch as endogenous opioid and dopaminergic systems are involved in smoking reinforcement, it is important to study mu opioid receptor (OPRM1) A118G (rs1799971), dopamine D2 receptor (DRD2) Taq1A (rs1800497) genotypes, and sex differences among patients with schizophrenia or bipolar disorder. Smokers and nonsmokers with schizophrenia (n=177) and bipolar disorder (n=113) were recruited and genotyped. They were classified into three groups: current smoker, former smoker, and never smoker by tobacco smoking status self-report...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28548574/overdose-education-and-naloxone-distribution-for-veterans-with-opioid-use-disorder-results-from-a-pilot-initiative
#14
Grace Chang, Michelle Davids, Alan Kershaw
Background Patients with opioid use disorder (OUD) are at high risk of overdose. To minimize that risk, a program offering intranasal naloxone rescue kits was piloted at a Veterans Administration Hospital. The purpose of this study was to characterize the veterans who accepted these potentially lifesaving kits. Methods Retrospective medical chart review of 158 veterans with OUD receiving treatment on either the inpatient psychiatry detoxification units or outpatient methadone maintenance setting who were offered overdose education and naloxone rescue (OEND) kits...
May 26, 2017: Journal of Addictive Diseases
https://www.readbyqxmd.com/read/28548564/eating-habits-and-food-additive-intakes-are-associated-with-emotional-states-based-on-eeg-and-hrv-in-healthy-korean-children-and-adolescents
#15
Jin Young Kim, Hye Lim Kang, Dae-Keun Kim, Seung Wan Kang, Yoo Kyoung Park
PURPOSE: Recent study suggests that psychological issues and eating habits are closely related. In this study, we aimed to find the association between eating habits and intakes of artificial sweeteners with emotional states of schoolchildren using quantitatively analyzing objective biosignals. METHODS: The study was conducted at the National Standard Reference Data Center for Korean EEG as a cross-sectional study. Three hundred eighteen healthy children who have not been diagnosed with neurologic or psychiatric disorders were evaluated (168 girls and 150 boys; mean age of 11...
May 26, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28548559/the-yucatan-minipig-tmj-disc-structure-function-relationships-support-its-suitability-for-human-comparative-studies
#16
Natalia Vapniarsky, Ashkan Aryaei, Boaz Arzi, Jerry C Hu, David C Hatcher, Kyriacos A Athanasiou
Frequent involvement of the disc in temporomandibular joint (TMJ) disorders warrants attempts to tissue engineer TMJ disc replacements. Physiologically, a great degree of similarity is seen between humans and farm pigs (FPs), but the pig's rapid growth confers a significant challenge for in vivo experiments. Minipigs have a slower growth rate and are smaller than FPs, but minipig TMJ discs have yet to be fully characterized. The objective of this study was to determine the suitability of the minipig for TMJ studies by extensive structural and functional characterization...
May 26, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28548543/systematic-review-of-clinical-guidance-documents-for-autism-spectrum-disorder-diagnostic-assessment-in-select-regions
#17
Melanie Penner, Evdokia Anagnostou, Lana Y Andoni, Wendy J Ungar
Clinical guidance documents play an important role in ensuring access to high-quality autism spectrum disorder diagnostic assessment practices. The objective was to perform a systematic review of professional association and government clinical guidance documents for autism spectrum disorder diagnostic assessment, analyzing their quality and content. The government search was limited to English-speaking, single-payer, publicly funded health systems. A quality appraisal was conducted by two appraisers using the Appraisal of Guidelines Research and Evaluation, second edition tool...
May 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28548308/validation-of-a-french-version-of-the-sleep-condition-indicator-a-clinical-screening-tool-for-insomnia-disorder-according-to-dsm-5-criteria
#18
Sophie Bayard, Cindy Lebrun, Khaalid Hassan Maudarbocus, Vanessa Schellaert, Alicia Joffre, Esther Ferrante, Marie Le Louedec, Alice Cournoulat, Marie-Christine Gely-Nargeot, Annemarie I Luik
Insomnia disorder is frequent in the population, yet there is no French screening instrument available that is based on the updated DSM-5 criteria. We evaluated the validity and reliability of the French version of an insomnia screening instrument based on DSM-5 criteria, the Sleep Condition Indicator, in a population-based sample of adults. A total of 366 community-dwelling participants completed a face-to-face clinical interview to determine insomnia disorder against DSM-5 criteria and several questionnaires including the French Sleep Condition Indicator version...
May 26, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28548297/dysregulation-of-the-causative-genes-for-hereditary-parkinsonism-in-the-midbrain-in-parkinson-s-disease
#19
Yun Joong Kim, Junbeom Jeon, Jaemoon Shin, Nan Young Kim, Jeong Hoon Hong, Jae-Min Oh, SangKyoon Hong, Yeo Jin Kim, Young-Eun Kim, Suk Yun Kang, Hyeo-Il Ma, Unjoo Lee, Jeehee Yoon
BACKGROUND AND OBJECTIVES: Many hereditary movement disorders with complex phenotypes without a locus symbol prefix for familial PD present as parkinsonism; however, the dysregulation of genes associated with these phenotypes in the SNpc of PD patients has not been systematically studied. METHODS: Gene set enrichment analyses were performed using 10 previously published genome-wide expression datasets obtained by laser-captured microdissection of pigmented neurons in the SNpc...
May 26, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28548291/practitioner-review-empirical-evolution-of-youth-psychotherapy-toward-transdiagnostic-approaches
#20
REVIEW
Lauren Krumholz Marchette, John R Weisz
BACKGROUND: Psychotherapy for children and adolescents (herein, 'youths') has grown more precise and focused over the decades, shifting toward empirically supported treatments standardized via therapist manuals. The manuals have increasingly emphasized precise targeting of single disorders or problems, or homogenous clusters. These focal treatments represent a valuable advance, with intervention benefit documented in hundreds of studies. However, relatively few of these treatments are widely used in everyday clinical practice, and their level of benefit may not be ideal, particularly in practice contexts and when compared to usual clinical care...
May 26, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
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