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https://www.readbyqxmd.com/read/27263757/fluorescence-guided-surgery-for-the-treatment-of-medication-related-osteonecrosis-of-the-jaw-a-prospective-cohort-study
#1
Sven Otto, Oliver Ristow, Christoph Pache, Matthias Troeltzsch, Riham Fliefel, Michael Ehrenfeld, Christoph Pautke
INTRODUCTION: The delineation of the necrotic bone is a crucial step in the surgical treatment of medication-related osteonecrosis of the jaw (MRONJ). Several different approaches have been described including the innovative technique of fluorescence-guided surgery. However, until now there is a lack of data regarding the outcome. Therefore, the aim of the present study is to investigate the long-term success rates of fluorescence-guided surgery in the treatment of MRONJ. PATIENTS AND METHODS: 54 Patients were prospectively assigned for surgical treatment of medication-related osteonecrosis of the jaw using fluorescence-guided surgery...
August 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27121913/usefulness-of-a-fluorescence-visualization-system-for-the-detection-of-oral-precancerous-and-early-cancerous-lesions
#2
Yuichi Ohnishi, Tomoko Fujii, Yoshihide Ugaki, Hiroki Yasui, Masahiro Watanabe, Suguru Dateoka, Kenji Kakudo
Early detection of precancerous and early cancerous lesions could greatly reduce both the mortality and morbidity of oral cancer. The objective of this study was to analyze a fluorescence visualization (FV) system for the detection of precancerous and early cancerous lesions in rat tongue carcinogenesis and human oral cancerous lesions using for the first time a 4NQO rat model and human tissue. Based on the results from the rat tongue carcinogenesis model, under direct FV, the normal oral mucosa emitted various shades of pale green autofluorescence...
July 2016: Oncology Reports
https://www.readbyqxmd.com/read/26963199/autofluorescence-and-diagnostic-accuracy-of-lesions-of-oral-mucosa-a-pilot-study
#3
Enric Jané-Salas, Andrés Blanco-Carrión, Lluís Jover-Armengol, José López-López
The purpose of this study was to determine the accuracy of autofluorescence techniques for diagnosing oral mucosa lesions, using as reference pattern for comparison the visual diagnosis made by a clinical specialist. A pilot study was conducted with 60 patients divided in a control group without mucosal pathology and a study group with known clinical history for mucosal pathology. Both groups were examined by an oral medicine specialist and by a general dentist who used VELscope(r) system, which applies tissue fluorescence visualization to identify oral mucosal abnormalities...
November 2015: Brazilian Dental Journal
https://www.readbyqxmd.com/read/26946209/efficacy-of-light-based-detection-systems-for-early-detection-of-oral-cancer-and-oral-potentially-malignant-disorders-systematic-review
#4
R Nagi, Y-B Reddy-Kantharaj, N Rakesh, S Janardhan-Reddy, S Sahu
BACKGROUND: Earlier detection of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) is essential for dental professionals to improve patient survival rates. The aim of this systematic review is to to evaluate the effectiveness of devices that utilise the principles of chemiluminescence and tissue autofluorescence as adjuncts in the detection of OSCC and OPMD. MATERIAL AND METHODS: The electronic retrieval systems and databases searched for relevant articles were PubMed [MEDLINE] and Science direct...
2016: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/26535106/fluorescence-guided-bone-resection-by-using-visually-enhanced-lesion-scope-in-diffuse-chronic-sclerosingosteomyelitis-of-the-mandible-clinical-and-pathological-evaluation
#5
Daigo Yoshiga, Masaaki Sasaguri, Kou Matsuo, Sei Yoshida, Masataka Uehara, Manabu Habu, Kazuya Haraguchi, Tatsurou Tanaka, Yasuhiro Morimoto, Izumi Yoshioka, Kazuhiro Tominaga
UNLABELLED: Diffuse chronic sclerosingosteomyelitis (DCSO) is a refractory disease, becausethe etiology and pathogenesis remain poorly understood and to determine the border betweenunhealthy boneandhealthybone is difficult. However, progressive inflammation, clinical symptoms and a high recurrence rate of DCSO were the reasons for surgical treatment. We report a case of a 66-year old woman with DCSO of the right side of mandible who was treated with hemimandibulectomy and simultaneous reconstruction by vascularized free fibula flap...
October 2015: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/26522601/efficacy-of-autofluorescence-imaging-as-an-adjunctive-technique-for-examination-and-detection-of-oral-potentially-malignant-disorders-a-systematic-review
#6
Kamran Habib Awan, Shankargouda Patil
BACKGROUND: Oral cancer is a serious global issue and early diagnosis of oral cancer is the key in reducing the high mortality rate. Autofluorescence properties of oral mucosa have been gaining interest in the field of early diagnosis of oral premalignant lesions. OBJECTIVE: The aim of the study was to evaluate the clinical usefulness of an autofluorescence based imaging system to detect oral premalignant and malignant lesions. MATERIALS AND METHODS: A systematic review of the English-language literature to evaluate the effectiveness of visually enhanced lesion scope (VELscope) published between 1966 and March, 2014 was undertaken...
September 2015: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/26472652/diagnostics-of-tongue-coating-using-autofluorescence
#7
Irène Hitz Lindenmüller, Paco Weiss, Michael Volken, Andreas Filippi
In the present study, the VELscope® autofluorescence device was used in addition to the Winkel Tongue Coating Index (WTCI) to evaluate tongue coating; a corresponding index was developed for evaluation with VELscope®. The distinct orange fluorescence of the tongue dorsum caused by autofluorescent bacterially colonized areas motivates halitosis patients to optimize tongue hygiene. The tongue dorsum of 100 volunteers (35 males, 65 females, average age 51 years) was photographed with and without the autofluorescence device...
2015: Swiss Dental Journal
https://www.readbyqxmd.com/read/26267490/autofluorescence-imaging-in-recurrent-oral-squamous-cell-carcinoma
#8
Martin Scheer, Juliana Fuss, Mehmet Ali Derman, Matthias Kreppel, Jörg Neugebauer, Daniel Rothamel, Uta Drebber, Joachim E Zoeller
The survival of patients with oral cancer is decreased by locoregional recurrence after an initial multimodal treatment. In order to identify lesions in the oral cavity for a possible recurrence, clinical evaluation as well as MRI or CT scanning is advised. The evaluation of mucosa lesions is hampered by changes related to radio- and chemotherapy as well as reconstruction with tissue flaps. Several techniques for easier identification of tissue abnormalities in the oral cavity have been advocated as adjuncts in order to facilitate identification...
March 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/26236687/evaluation-of-premalignant-and-malignant-lesions-by-fluorescent-light-velscope
#9
Dania Sawan, Ammar Mashlah
AIM: The purpose of this study was the early detection of premalignant and malignant oral soft lesions by fluorescent light (VELscope). MATERIALS AND METHODS: A total of 748 patients were evaluated through clinical and fluorescent light analysis of the entire oral cavity. Any lesion that was detected underwent a surgical excision biopsy as the golden standard for the detection of the lesion's histology; then a comparison was made between the results to assure the efficacy of the fluorescent light analysis outcome...
May 2015: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/26155330/combination-of-autofluorescence-imaging-and-salivary-protoporphyrin-in-oral-precancerous-and-cancerous-lesions-non-invasive-tools
#10
Jasdeep Kaur, Reinhilde Jacobs
BACKGROUND: Normal and cancerous tissues have distinct auto-fluorescence properties because of differences in their biophysical and biochemical agents. Scientific evidences related to diagnostic fluorescence imaging for detection of oral precancerous and cancerous lesions are very limited. OBJECTIVES: The aim of this study was to find out potential relationships between serum, salivary and tissue protoporphyrin IX ( PX) levels in subjects with or without oral precancerous and cancerous lesions...
April 2015: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/26037792/intraoperative-detection-of-viable-bone-with-fluorescence-imaging-using-visually-enhanced-lesion-scope-in-patients-with-bisphosphonate-related-osteonecrosis-of-the-jaw-clinical-and-pathological-evaluation
#11
D Yoshiga, M Sasaguri, K Matsuo, S Kokuryou, M Habu, M Oda, M Kodama, H Tsurushima, O Sakaguchi, T Sakurai, J Tanaka, Y Morimoto, I Yoshioka, K Tominaga
UNLABELLED: There is no standard surgical protocol of bisphosphonate-related osteonecrosis of the jaws (BRONJ), because of the impossibility to visualize this feature intraoperatively. The aim of this study was to introduce how to provide preoperative labeling of the viable bone with minocycline bone fluorescence technique (MBFT) by using VELscope® and investigate histopathologically. INTRODUCTION: The American Association of Oral and Maxillofacial Surgeons (AAOMS) and the Japanese Society of Oral and Maxillofacial Surgeons (JSOMS) now recommend a more conservative treatment strategy...
July 2015: Osteoporosis International
https://www.readbyqxmd.com/read/25690067/the-use-of-fluorescence-technology-versus-visual-and-tactile-examination-in-the-detection-of-oral-lesions-a-pilot-study
#12
Hadeel M Ayoub, Tara L Newcomb, Gayle B McCombs, Marshall Bonnie
PURPOSE: This study compared the effectiveness of the VELscope® Vx versus visual and tactile intraoral examination in detecting oral lesions in an adult, high risk population. METHODS: The pilot study compared the intra oral findings between 2 examination types. The sample was comprised of 30 participants who were addicted to either cigarettes or a dual addiction (cigarettes plus hookah). High risk population was defined as males who were current cigarette smokers or had a dual addiction...
February 2015: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/25183259/the-use-of-light-based-optical-detection-systems-as-adjuncts-in-the-detection-of-oral-cancer-and-oral-potentially-malignant-disorders-a-systematic-review
#13
REVIEW
A Rashid, S Warnakulasuriya
INTRODUCTION: In recent decades, optical techniques utilising the principles of chemiluminescence and tissue autofluorescence have emerged to facilitate the early detection of any oral mucosal changes suspicious of cancer. PURPOSE: To evaluate the effectiveness of devices that utilise the principles of chemiluminescence and tissue autofluorescence as adjuncts in the detection of oral cancer and oral potentially malignant disorders (OPMDs). METHODS: A systematic review of the published literature to evaluate the effectiveness of the ViziLite(®) and ViziLite(®) Plus with toluidine blue, MicroLux™/DL and the VELscope™ as aids in the detection of oral cancer and OPMDs...
May 2015: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/25128260/auto-fluorescence-of-the-bone-and-its-use-for-delineation-of-bone-necrosis
#14
O Ristow, C Pautke
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a challenging complication of long-term bisphosphonate treatment. Currently, the drawback in the surgical management of BRONJ is the difficulty distinguishing between viable and necrotic bone. Intraoperative bone fluorescence induced by tetracyclines has been shown to be a valuable aid to overcome this problem. In this technical note we report the finding that viable bone is auto-fluorescent using the VELscope Vx fluorescence lamp. Necrotic bone shows an altered fluorescence pattern (pale or no fluorescence)...
November 2014: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/25096826/assessment-of-a-decision-making-protocol-to-improve-the-efficacy-of-velscope%C3%A2-in-general-dental-practice-a-prospective-evaluation
#15
Nirav Bhatia, Marie Anne T Matias, Camile S Farah
BACKGROUND: VELscope™ is a device designed to help detect potentially malignant disorders of the oral mucosa at an early stage using direct tissue autofluorescence. Previous research indicates a high rate of false positives using this device. This study assesses a decision making protocol for the detection of oral mucosal lesions using conventional oral examination and VELscope™ in a general dental practice setting. MATERIALS AND METHODS: 305 patients presenting for general dental treatment were screened by a general dental practitioner (GDP) for oral mucosal lesions using incandescent light (conventional oral examination - COE), followed by VELscope™ and then by correlating the findings from these two examinations...
October 2014: Oral Oncology
https://www.readbyqxmd.com/read/24078812/advances-in-optical-adjunctive-aids-for-visualisation-and-detection-of-oral-malignant-and-potentially-malignant-lesions
#16
REVIEW
Nirav Bhatia, Yastira Lalla, An N Vu, Camile S Farah
Traditional methods of screening for oral potentially malignant disorders and oral malignancies involve a conventional oral examination with digital palpation. Evidence indicates that conventional examination is a poor discriminator of oral mucosal lesions. A number of optical aids have been developed to assist the clinician to detect oral mucosal abnormalities and to differentiate benign lesions from sinister pathology. This paper discusses advances in optical technologies designed for the detection of oral mucosal abnormalities...
2013: International Journal of Dentistry
https://www.readbyqxmd.com/read/24011463/intraoperative-efficiency-of-fluorescence-imaging-by-visually-enhanced-lesion-scope-velscope-in-patients-with-bisphosphonate-related-osteonecrosis-of-the-jaw-bronj
#17
Alexandre T Assaf, Tomislav A Zrnc, Björn Riecke, Johannes Wikner, Jozef Zustin, Reinhard E Friedrich, Max Heiland, Ralf Smeets, Alexander Gröbe
OBJECTIVES: The purpose of this study was to determine the potential of tissue fluorescence imaging by using Visually Enhanced Lesion Scope (VELscope) for the detection of osteonecrosis of the jaw induced by bisphosphonates (BRONJ). METHODS: We investigated 20 patients (11 females and 9 males; mean age 74 years, standard deviation ± 6.4 years), over a period of 18 month with the diagnosis of BRONJ in this prospective cohort study. All patients received doxycycline as a fluorescending marker for osseous structures...
July 2014: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/23967796/the-detection-of-oral-pre-malignant-lesions-with-an-autofluorescence-based-imaging-system-velscope%C3%A2-a-single-blinded-clinical-evaluation
#18
RANDOMIZED CONTROLLED TRIAL
Henning Hanken, Juliane Kraatz, Ralf Smeets, Max Heiland, Alexandre Thomas Assaf, Marco Blessmann, Wolfgang Eichhorn, Till Sebastian Clauditz, Alexander Gröbe, Andreas Kolk, Madiha Rana
OBJECTIVE: The disease specific five-year survival rate especially for patients with advanced oral cancer has not improved significantly over the period of time. The most effective way of combating this dilemma is an early detection, diagnosis and eradication of early-stage lesions and their precursors. The use of VELscope® using an autofluorescence as a diagnostic tool might be useful in early detection of oral malignant lesions. MATERIALS AND METHODS: 120 patients with suspicious oral premalignant lesions were examined with two examination methods...
2013: Head & Face Medicine
https://www.readbyqxmd.com/read/23550336/denmat-led-dental-s-velscope-vx-saving-lives-by-detecting-oral-cancer-early
#19
(no author information available yet)
No abstract text is available yet for this article.
January 2013: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/23083477/the-role-of-direct-visual-fluorescent-examination-velscope-in-routine-screening-for-potentially-malignant-oral-mucosal-lesions
#20
Kristin K McNamara, Brent D Martin, Erik W Evans, John R Kalmar
OBJECTIVE: Direct visual fluorescent examination (DVFE) is a proposed adjunct to conventional oral examination (COE). We evaluate the benefit of DVFE in screening for potentially malignant mucosal lesions in a general population of patients presenting for dental care. STUDY DESIGN: A total of 130 patients were evaluated by COE followed by DVFE. Areas clinically suspicious by COE or with positive DVFE (visual fluorescence loss [VFL]) underwent surgical biopsy. Association between COE and DVFE was assessed and compared with histopathology...
November 2012: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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