Myrthe Y C van der Heide, Tom E Verstraelen, Freyja H M van Lint, Laurens P Bosman, Remco de Brouwer, Virginnio M Proost, Esmée van Drie, Karim Taha, Aeilko H Zwinderman, Cathelijne Dickhoff, Bas A Schoonderwoerd, Tjeerd Germans, Arjan C Houweling, Juan R Gimeno-Blanes, Paul A van der Zwaag, Rudolf A de Boer, Moniek G P J Cox, J Peter van Tintelen, Arthur A M Wilde
AIMS: Recently, a genetic variant-specific prediction model for phospholamban (PLN) p.(Arg14del)-positive individuals was developed to predict individual major ventricular arrhythmia (VA) risk to support decision-making for primary prevention implantable cardioverter defibrillator (ICD) implantation. This model predicts major VA risk from baseline data, but iterative evaluation of major VA risk may be warranted considering that the risk factors for major VA are progressive. Our aim is to evaluate the diagnostic performance of the PLN p...
March 30, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology