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Severe acute malnutrition

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https://www.readbyqxmd.com/read/29783749/differential-impact-of-malnutrition-on-health-outcomes-among-indigenous-and-non-indigenous-adults-admitted-to-hospital-in-regional-australia-a-prospective-cohort-study
#1
Natasha Morris, Simon Stewart, Malcolm Riley, Graeme Maguire
The burden of malnutrition in Indigenous people is a major health priority and this study's aims are to understand health outcomes among Indigenous and non-Indigenous patients. This cohort study includes 608 medical inpatients in three regional hospitals. Participants were screened for malnutrition using the Subjective Global Assessment tool. Hospital length of stay, discharge destination, 30-day and six-month hospital readmission and survival were measured. Although no significant difference was observed between Indigenous participants who were malnourished or nourished ( p = 0...
May 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29771994/prevalence-outcome-and-quality-of-care-among-children-hospitalized-with-severe-acute-malnutrition-in-kenyan-hospitals-a-multi-site-observational-study
#2
Susan Gachau, Grace Irimu, Philip Ayieko, Samuel Akech, Ambrose Agweyu, Mike English
BACKGROUND: Severe acute malnutrition (SAM) remains a major cause of admission and inpatient mortality worldwide in children aged less than 5 years. In this study, we explored SAM prevalence and outcomes in children admitted in 13 Kenyan hospitals participating in a Clinical Information Network (CIN). We also describe their immediate in-patient management. METHODS: We analyzed data for children aged 1-59 months collected retrospectively from medical records after discharge...
2018: PloS One
https://www.readbyqxmd.com/read/29760577/perceptions-of-acute-malnutrition-and-its-management-in-infants-under-6-months-of-age-a-qualitative-study-in-rural-bangladesh
#3
Yasir Arafat, M Munirul Islam, Nicki Connell, Golam Mothabbir, Marie McGrath, James A Berkley, Tahmeed Ahmed, Marko Kerac
Background: World Health Organization guidelines advise community-based care (CBC) for "uncomplicated" severe acute malnutrition (SAM) infants <6 months old (u6m), whereas current national protocols refer to inpatient care. Our aim was to inform and shape future management strategies by understanding caregivers' and different stakeholders' perceptions on malnutrition among infants u6m on barriers/facilitators to future CBC. Methods: The methods used in this study are as follows: in-depth interviews and focus group discussions (FGDs) in southern Bangladesh, thematic analysis of transcripts, and sample size by data saturation...
2018: Clinical Medicine Insights. Pediatrics
https://www.readbyqxmd.com/read/29756960/socio-demographic-variables-and-underlying-pathologies-associated-to-nutritional-status-of-hospitalized-children-in-a-secondary-tertiary-level-hospital
#4
Nelly Carolina Muñoz Esparza, Edgar Manuel Vasquez-Garibay, Alfredo Larrosa-Haro, Enrique Romero-Velarde
OBJECTIVE: the purpose was to evaluate the nutritional status in hospitalized children according to their socio-demographic variables, underlying pathology and based on hospital length of stay. METHODS: seven-hundred and sixty-three hospitalized patients of the Civil Hospital of Guadalajara Dr. Juan I. Menchaca were included in a cross-sectional study. The following anthropometric indices were taken: weight/length, weight/height, weight/age, length/age, height/age, head circumference/age and BMI/age...
February 27, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29748656/the-capacity-load-model-of-non-communicable-disease-risk-understanding-the-effects-of-child-malnutrition-ethnicity-and-the-social-determinants-of-health
#5
REVIEW
Jonathan C K Wells
The capacity-load model is a conceptual model developed to improve understanding of the life-course aetiology of non-communicable diseases (NCDs) and their ecological and societal risk factors. The model addresses continuous associations of both (a) nutrition and growth patterns in early life and (b) lifestyle factors at older ages with NCD risk. Metabolic capacity refers to physiological traits strongly contingent on early nutrition and growth during the first 1000 days, which promote the long-term capacity for homeostasis in the context of fuel metabolism and cardiovascular health...
May 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29740973/findings-from-a-cluster-randomised-trial-of-unconditional-cash-transfers-in-niger
#6
Victoria L Sibson, Carlos S Grijalva-Eternod, Garba Noura, Julia Lewis, Kwanli Kladstrup, Hassan Haghparast-Bidgoli, Jolene Skordis-Worrall, Tim Colbourn, Joanna Morrison, Andrew J Seal
Unconditional cash transfers (UCTs) are used as a humanitarian intervention to prevent acute malnutrition, despite a lack of evidence about their effectiveness. In Niger, UCT and supplementary feeding are given during the June-September "lean season," although admissions of malnourished children to feeding programmes may rise from March/April. We hypothesised that earlier initiation of the UCT would reduce the prevalence of global acute malnutrition (GAM) in children 6-59 months old in beneficiary households and at population level...
May 8, 2018: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29732931/determinants-of-the-global-prices-of-ready-to-use-therapeutic-foods
#7
Jakub Kakietek
BACKGROUND: A therapy based on ready-to-use therapeutic food (RUTF) in outpatient settings is considered the gold standard in the treatment of severe acute malnutrition in children younger than 5 years. The price of RUTF is the key cost driver of the therapy. However, no studies to date have systematically examined the determinants of RUTF prices. OBJECTIVE: This article presents the first analysis of factors associated with the prices of RUTF, focusing on the impact of competition and tendering...
January 1, 2018: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/29726948/children-with-poor-linear-growth-are-at-risk-for-repeated-relapse-to-wasting-after-recovery-from-moderate-acute-malnutrition
#8
Heather C Stobaugh, Beatrice L Rogers, Irwin H Rosenberg, Patrick Webb, Kenneth M Maleta, Mark J Manary, Indi Trehan
Background: Nutrition programs frequently approach wasting and stunting as 2 separate conditions with distinct causes and effects. Although several cross-sectional studies have identified an association between the 2 conditions, longitudinal studies are useful to quantify the risk of acute malnutrition based on the trajectory of linear growth. Objective: We analyzed data from a longitudinal study to explore associations between linear growth and relapse to acute malnutrition in high-risk children during the year after recovery from moderate acute malnutrition (MAM)...
May 3, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29722846/high-dose-vitamin-d3-in-the-treatment-of-severe-acute-malnutrition-a-multicenter-double-blind-randomized-controlled-trial
#9
Javeria Saleem, Rubeena Zakar, Muhammad Z Zakar, Mulugeta Belay, Marion Rowe, Peter M Timms, Robert Scragg, Adrian R Martineau
Background: Vitamin D deficiency is common in children with severe acute malnutrition, in whom it is associated with severe wasting. Ready-to-use therapeutic food (the standard treatment) contains modest amounts of vitamin D that do not reliably correct deficiency. Objective: The aim of this study was to determine whether high-dose oral vitamin D3 enhances weight gain and development in children with uncomplicated severe acute malnutrition. Design: We conducted a randomized placebo-controlled trial of high-dose vitamin D3 supplementation in children aged 6-58 mo with uncomplicated severe acute malnutrition in Pakistan...
May 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29715324/correction-characterizing-the-metabolic-phenotype-of-intestinal-villus-blunting-in-zambian-children-with-severe-acute-malnutrition-and-persistent-diarrhea
#10
(no author information available yet)
[This corrects the article DOI: 10.1371/journal.pone.0192092.].
2018: PloS One
https://www.readbyqxmd.com/read/29690916/combined-protocol-for-acute-malnutrition-study-compas-in-rural-south-sudan-and-urban-kenya-study-protocol-for-a-randomized-controlled-trial
#11
Jeanette Bailey, Natasha Lelijveld, Bethany Marron, Pamela Onyoo, Lara S Ho, Mark Manary, André Briend, Charles Opondo, Marko Kerac
BACKGROUND: Acute malnutrition is a continuum condition, but severe and moderate forms are treated separately, with different protocols and therapeutic products, managed by separate United Nations agencies. The Combined Protocol for Acute Malnutrition Study (ComPAS) aims to simplify and unify the treatment of uncomplicated severe and moderate acute malnutrition (SAM and MAM) for children 6-59 months into one protocol in order to improve the global coverage, quality, continuity of care and cost-effectiveness of acute malnutrition treatment in resource-constrained settings...
April 24, 2018: Trials
https://www.readbyqxmd.com/read/29690899/the-compas-trial-combined-treatment-model-for-acute-malnutrition-study-protocol-for-the-economic-evaluation
#12
Natasha Lelijveld, Jeanette Bailey, Amy Mayberry, Lani Trenouth, Dieynaba S N'Diaye, Hassan Haghparast-Bidgoli, Chloe Puett
BACKGROUND: Acute malnutrition is currently divided into severe (SAM) and moderate (MAM) based on level of wasting. SAM and MAM currently have separate treatment protocols and products, managed by separate international agencies. For SAM, the dose of treatment is allocated by the child's weight. A combined and simplified protocol for SAM and MAM, with a standardised dose of ready-to-use therapeutic food (RUTF), is being trialled for non-inferior recovery rates and may be more cost-effective than the current standard protocols for treating SAM and MAM...
April 24, 2018: Trials
https://www.readbyqxmd.com/read/29678205/management-of-severe-acute-malnutrition-by-cow-milk-in-resource-constraints-settings-experience-of-the-nutritional-centre-of-the-university-clinics-of-graben
#13
Mupenzi Mumbere, F Katsuva Mbahweka, B P Furaha Nzanzu
BACKGROUND: Severe acute malnutrition is defined as a weight for height z-score < - 3 standard deviation. Since 2000, joint efforts of the World Health Organization and United Nations Children's Fund allowed to standardize the management of acute malnutrition by improving outcome and preventing complications with the introduction of therapeutic milk and ready-to-use therapeutic foods. However, in the Democratic Republic of Congo, many health facilities face therapeutic milk shortage while managing severe acute malnutrition...
April 20, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29667569/ethnic-and-age-differences-in-prediction-of-mortality-by-mid-upper-arm-circumference-in-children-below-3-years-of-age-in-nepal
#14
Avni Gupta, James M Tielsch, Subarna K Khatry, Steven C LeClerq, Luke C Mullany, Joanne Katz
OBJECTIVE: To assess ethnicity- and age-modified associations between mid-upper arm circumference (MUAC) and mortality in Nepalese children and whether sociodemographic factors explain these associations. DESIGN: Secondary data analysis of children followed until 3 years of age. Estimated mortality hazard ratios (HR) for MUAC<11·5cm (recommended cut-off for identifying severe acute malnutrition among children ≥6 months old) compared with ≥11·5cm in younger (<6 months) and older children (≥6 months) of Pahadi and Madhesi ethnicity, adjusting for sex, socio-economic status (SES) and mother's education using Cox proportional hazard models...
April 18, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29657713/mid-upper-arm-circumference-based-case-detection-admission-and-discharging-of-under-five-children-in-a-large-scale-community-based-management-of-acute-malnutrition-program-in-nigeria
#15
Stanley Chitekwe, Sibhatu Biadgilign, Assaye Tolla, Mark Myatt
Background: Severe acute malnutrition (SAM) threatens the lives of millions of children worldwide particularly in low and middle-income countries (LMICs). Community-based management of acute malnutrition (CMAM) is an approach to treating large numbers of cases of severe acute malnutrition (SAM) in a community setting. There is a debate about the use of mid-upper arm circumference (MUAC) for admitting and discharging SAM children. This article describes the experience of using MUAC for screening, case-finding, referral, admission, and discharge in a large-scale CMAM program delivered through existing primary health care facilities in Nigeria...
2018: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29615143/recovery-and-relapse-from-severe-acute-malnutrition-after-treatment-a-prospective-observational-cohort-trial-in-pakistan
#16
Nancy M Dale, Laila Salim, Lindsey Lenters, Salim Sadruddin, Mark Myatt, Stanley H Zlotkin
OBJECTIVE: Millions of children suffer from severe acute malnutrition (SAM) in low- and middle- income countries. Much is known about the effectiveness of community treatment programmes (CMAM) but little is known about post-discharge outcomes after successful treatment. The present study aimed to evaluate post-discharge outcomes of children cured of SAM. DESIGN: Prospective, observational cohort study. Children with SAM who were discharged as cured were followed monthly for 6 months or until they experienced relapse to SAM...
April 4, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29605573/multi-site-implementation-of-nutrition-screening-and-diagnosis-in-medical-care-units-success-of-the-more-2-eat-project
#17
Heather H Keller, Renata Valaitis, Celia V Laur, Tara McNicholl, Yingying Xu, Joel A Dubin, Lori Curtis, Suzanne Obiorah, Sumantra Ray, Paule Bernier, Leah Gramlich, Marilee Stickles-White, Manon Laporte, Jack Bell
BACKGROUND: Improving the detection and treatment of malnourished patients in hospital is needed to promote recovery. AIM: To describe the change in rates of detection and triaging of care for malnourished patients in 5 hospitals that were implementing an evidence-based nutrition care algorithm. To demonstrate that following this algorithm leads to increased detection of malnutrition and increased treatment to mitigate this condition. METHODS: Sites worked towards implementing the Integrated Nutrition Pathway for Acute Care (INPAC), including screening (Canadian Nutrition Screening Tool) and triage (Subjective Global Assessment; SGA) to detect and diagnose malnourished patients...
March 22, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29599685/household-decision-making-around-food-in-rural-tajikistan-a-cross-sectional-study-to-help-extension-workers-in-the-field
#18
REVIEW
Elizabeth A Wood, Katharine McNamara, Agata Kowalewska, Nargiza Ludgate
This study was conducted to research and develop recommendations for gender transformative approaches that will address misconceptions around food and nutrition, and reducing barriers around dietary diversity within rural Khatlon Province, Tajikistan. Most of the population in Tajikistan live in rural areas and spend a large part of their income on food. While stunting in children under 5 years has decreased, acute malnutrition and the number of underweight children has increased. This is a qualitative, cross-sectional study that involved secondary data analysis, key informant interviews (KIIs), and focus group discussions (FGDs) to gauge appropriate interventions for agricultural extension agents seeking to improve the nutritional outcomes of their communities...
2018: Food & Nutrition Research
https://www.readbyqxmd.com/read/29595379/child-malnutrition-in-ifanadiana-district-madagascar-associated-factors-and-timing-of-growth-faltering-ahead-of-a-health-system-strengthening-intervention
#19
Sarah McCuskee, Andres Garchitorena, Ann C Miller, Lara Hall, Mohammed Ali Ouenzar, Victor R Rabeza, Ranto H Ramananjato, Hery-Tiana Rahaniraka Razanadrakato, Marius Randriamanambintsoa, Michele Barry, Matthew H Bonds
BACKGROUND: Child malnutrition, a leading cause of death and disability worldwide, is particularly severe in Madagascar, where 47% of children under 5 years are stunted (low height-for-age) and 8% are wasted (low weight-for-height). Widespread poverty and a weak health system have hindered attempts to implement life-saving malnutrition interventions in Madagascar during critical periods for growth faltering. OBJECTIVE: This study aimed to shed light on the most important factors associated with child malnutrition, both acute and chronic, and the timing of growth faltering, in Ifanadiana, a rural district of Madagascar...
2018: Global Health Action
https://www.readbyqxmd.com/read/29580238/the-effectiveness-of-treatment-for-severe-acute-malnutrition-sam-delivered-by-community-health-workers-compared-to-a-traditional-facility-based-model
#20
J L Alvarez Morán, G B Franck Alé, P Charle, N Sessions, S Doumbia, S Guerrero
BACKGROUND: In most health systems, Community Health Workers (CHWs) identify and screen for severe acute malnutrition (SAM) in the community. This study aimed to investigate the potential of integrating SAM identification and treatment delivered by CHWs, in order to improve the coverage of SAM treatment services. METHODS: This multicentre, randomised intervention study was conducted in Kita, Southwest Mali between February 2015 and February 2016. Treatment for uncomplicated SAM was provided in health facilities in the control area, and by Community Health Workers and health facilities in the intervention area...
March 27, 2018: BMC Health Services Research
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