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Unilateral testicular atrophy

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https://www.readbyqxmd.com/read/29083263/fifteen-years-experience-with-laparoscopic-inguinal-hernia-repair-in-infants-and-children
#1
Rafik Shalaby, Mohamed Abd Alrazek, Adham Elsaied, Ahmad Helal, Mohamad Mahfouz, Maged Ismail, Abdelmoniem Shams, Mohamad Magid
BACKGROUND: Laparoscopic inguinal hernia repair (LIHR) is gaining popularity with more studies validating its feasibility, safety, and efficacy. The aim of this work is to review our experience with LIHR in infants and children during the past 15 years, and present and evaluate our innovations of laparoscopic techniques. PATIENTS AND METHODS: A retrospective study of 1284 patients with congenital inguinal hernia (CIH) subjected to different techniques of LIHR from October 2000 to October 2015...
October 30, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28597284/comparison-of-single-incision-laparoscopic-percutaneous-extraperitoneal-closure-silpec-and-open-repair-for-pediatric-inguinal-hernia-a-single-center-retrospective-cohort-study-of-2028-cases
#2
Hizuru Amano, Yujiro Tanaka, Hiroshi Kawashima, Kyoichi Deie, Michimasa Fujiogi, Keisuke Suzuki, Kaori Morita, Tadashi Iwanaka, Hiroo Uchida
BACKGROUD: Recently, laparoscopic percutaneous extraperitoneal closure (LPEC) has gained increased popularity for pediatric inguinal hernia repair. To improve cosmesis, we developed single incision LPEC (SILPEC). The aim of this study was to assess the safety and feasibility of SILPEC compared with traditional open repair (OR). METHODS: This was a single-center retrospective cohort study of 2028 children who underwent inguinal hernia repair between April 2005 and August 2014...
June 8, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28573934/testicular-fibrous-hypoplasia-in-cynomolgus-monkeys-macaca-fascicularis-an-incidental-congenital-lesion
#3
Marcia E Pereira Bacares, Vimala Vemireddi, Dianne Creasy
Testicular fibrous hypoplasia is an incidental lesion characterized by replacement of the testicular parenchyma by mature collagen. A retrospective survey of hematoxylin and eosin-stained testicular sections from 722 purpose-bred Asian and 90 Mauritian cynomolgus monkeys from 56 safety assessment studies conducted between 1999 and 2011 was performed. The incidence of the lesion increased markedly over time. No cases occurred between 1999 and 2004. Between 2005 and 2009, the incidence ranged between 8.1% and 11...
January 1, 2017: Toxicologic Pathology
https://www.readbyqxmd.com/read/28389795/a-systematic-review-and-meta-analysis-concerning-single-site-laparoscopic-percutaneous-extraperitoneal-closure-for-pediatric-inguinal-hernia-and-hydrocele
#4
Yi Chen, Furan Wang, Hongji Zhong, Junfeng Zhao, Yan Li, Zhan Shi
BACKGROUND: Single-site laparoscopic percutaneous extraperitoneal closure (SLPEC) of hernia sac/processus vaginalis has been widely performed for repair of inguinal hernia/hydrocele in children. However, a variety of surgical instruments and techniques were used, and significant differences existed among the SLPEC reports. METHODS: A literature search was performed for all available studies concerning SLPEC for pediatric inguinal hernia/hydrocele in PubMed, Embase and Cochrane library...
April 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28025693/laparoscopic-versus-open-inguinal-hernia-repair-in-children-%C3%A2-3-a-randomized-controlled-trial
#5
RANDOMIZED CONTROLLED TRIAL
Colin D Gause, Maria G Sacco Casamassima, Jingyan Yang, Grace Hsiung, Daniel Rhee, Jose H Salazar, Dominic Papandria, Howard I Pryor, Dylan Stewart, Jeffrey Lukish, Paul Colombani, Nicole M Chandler, Emilie Johnson, Fizan Abdullah
PURPOSE: Laparoscopy is being increasingly applied to pediatric inguinal hernia repair. In younger children, however, open repair remains preferred due to concerns related to anesthesia and technical challenges. We sought to assess outcomes after laparoscopic and open inguinal hernia repair in children less than or equal to 3 years. METHODS: A prospective, single-blind, parallel group randomized controlled trial was conducted at three clinical sites. Children ≤3 years of age with reducible unilateral or bilateral inguinal hernias were randomized to laparoscopic herniorrhaphy (LH) or open herniorrhaphy (OH)...
March 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/27760628/-effectiveness-of-microsurgical-crossover-anastomosis-in-treating-complicated-obstructive-azoospermia
#6
P Li, H X Chen, Y H Huang, E L Zhi, R H Tian, H Zhao, F Yang, H F Sun, Y H Gong, Z J Zhu, Y Hong, Y D Liu, S J Xia, Z Li
Objective: To evaluate the efficacy and safety of microsurgical crossover vasovasostomy in treating complicated obstructive azoospermia. Methods: The data of 14 patients with complicated obstructive azoospermia treated with microsurgical crossover vasovasostomy were reviewed from October 2012 to March 2016.Ten of them underwent microsurgical crossover vasovasostomy. Intraoperative exploration revealed that 2 patients had vas deferens injury and contralateral testicular atrophy or epididymal obstruction due to previous hernia repair; 7 patients had obstruction of intracorporeal vas deferens on one side and epididymal obstruction on the other side; the other 1 patient had unilateral vasal obstruction with contralateral epididymal obstruction...
September 27, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27274891/clinical-and-histopathological-results-of-the-adult-patients-with-unilateral-cryptorchidism
#7
Ferhat Ateş, Hasan Soydan, Sezgin Okçelik, Abdullah Çırakoğlu, İsmail Yılmaz, Ercan Malkoç, Kenan Karademir
OBJECTIVE: To evaluate the clinical and histopathological results of adult unilateral cryptorchidism patients. MATERIAL AND METHODS: Data from adult unilateral cryptorchidism patients that underwent orchiectomy in our clinic between between January 2004 and March 2013 were retrospectively evaluated. Patients were divided into three groups as intra-abdominal, inguinal canal and superficial inguinal region according to the location of the undescended testes. Patients were also grouped according to their testicular volume (<4 cc, 4...
June 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27123660/-current-aspects-of-epididymo-orchitis
#8
A Pilatz, M Boecker, H-C Schuppe, F Wagenlehner
BACKGROUND: Acute epididymitis is an inflammation of the epididymis. It mostly occurs unilaterally and may spread to the testis ('epididymo-orchitis') if untreated. Increasing technological advances allow for an even more detailed examination of concurrent symptoms such as ejaculate changes and the whole spectrum of pathogenic agents, which ranges from sexually transmitted pathogens such as Chlamydia and gonococci to enterobacteria and, rarely, viruses. This review summarises major aspects of the disease including the latest scientific findings...
May 2016: Aktuelle Urologie
https://www.readbyqxmd.com/read/27073306/a-comparative-study-on-trans-umbilical-single-port-laparoscopic-approach-versus-conventional-repair-for-incarcerated-inguinal-hernia-in-children
#9
Zhang Jun, Ge Juntao, Liu Shuli, Long Li
PURPOSE: The purpose of this study is to determine whether singleport laparoscopic repair (SLR) for incarcerated inguinal hernia in children is superior toconventional repair (CR) approaches. METHOD: Between March 2013 and September 2013, 126 infants and children treatedwere retrospectively reviewed. All the patients were divided into three groups. Group A (48 patients) underwent trans-umbilical SLR, group B (36 patients) was subjected to trans-umbilical conventional two-port laparoscopic repair (TLR) while the conventional open surgery repair (COR) was performed in group C (42 patients)...
April 2016: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/26973822/outcomes-of-laparoscopic-treatment-modalities-for-unilateral-non-palpable-testes
#10
Nurullah Hamidi, Onur Telli, Uygar Bagci, Baris Esen, Mehmet Ali Karagoz, Ahmet Metin Hascicek, Tarkan Soygur, Berk Burgu
PURPOSE: To date, laparoscopy has gradually become the gold standard for treatment of non-palpable testicles (NPT) with different success and complication rates. In this study, we aimed to evaluate outcomes of laparoscopic approaches for NPT. MATERIALS AND METHODS: We reviewed data of 82 consecutive patients who underwent laparoscopic treatment for unilateral NPT at two institutions by two high volume surgeons from 2004 January to 2014 December. Laparoscopic-assisted orchidopexy (LAO) and two-stage Fowler-Stephens technique (FST) was performed for 45 and 37 patients, respectively...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/26824668/opinion-comment-on-evaluation-and-treatment-of-cryptorchidism-aua-aap-and-nordic-consensus-guidelines
#11
REVIEW
Faruk Hadziselimovic
The ultimate goal in the treatment of cryptorchidism is to achieve normal fertility. However, in a substantial number of cryptorchid males, early and apparently successful orchidopexy does not improve fertility as it does not address the underlying pathophysiological cause, namely, the impaired transformation of gonocytes into Ad spermatogonia. It is important to realize that over half the patients presenting with unilateral cryptorchidism and the majority of those presenting with bilateral cryptorchidism have abnormal spermiogram which indicates that unilateral cryptorchidism is in fact a bilateral disease and therefore a serious andrological problem...
2016: Urologia Internationalis
https://www.readbyqxmd.com/read/26472657/laparoscopic-management-of-recurrent-inguinal-hernia-in-childhood
#12
Rafik Shalaby, Maged Ismail, Samir Gouda, Abdel Aziz Yehya, Ibrahim Gamaan, Refaat Ibrahim, Sayed Hassan, Ahmad Alazab
BACKGROUND: Open repair of recurrent inguinal hernias [RIH] in infancy and childhood is difficult and there is definite risk of damaging the vas deferens and testicular vessels. Laparoscopic repair of RIH has the benefit of avoiding the previous operative site. The aim of this study is to present our experience with laparoscopic repair of RIH either after open or laparoscopic hernia repair with stress on technical refinements to prevent recurrence. PATIENTS AND METHODS: This is a retrospective study of laparoscopic repair of RIH...
November 2015: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/26343974/hypospadias-and-concomitant-undescended-testis-comparison-of-no-skin-incision-with-inguinal-and-scrotal-skin-incision-orchiopexy
#13
Shabnam Sabetkish, Abdol-Mohammad Kajbafzadeh, Nastaran Sabetkish
BACKGROUND: To present the feasibility of no skin incision orchiopexy in children with concomitant hypospadias and undescended testis (UDT) by a single subcoronal incision technique. To introduce the creation of subdartos muscle scrotal pouch with no scrotal skin incision. METHODS: From one thousand and twenty-one children with hypospadias, 61 patients presented with concomitant palpable UDT and hypospadias. In group I (N = 34) single subcoronal incision with no scrotal skin incision was applied...
October 2015: International Journal of Surgery
https://www.readbyqxmd.com/read/26267036/the-case-of-the-shrinking-testis
#14
Dwayne Tun Soong Chang, Isaac Andrew Thyer, Dickon Hayne, Darren Jonathan Katz
We report the case of a man with idiopathic lymphocytic orchitis (LO) manifested by undifferentiated testicular pain and atrophy. Conventional investigation results were unremarkable. Oral ciprofloxacin only improved the pain temporarily. Scrotal exploration surgery was performed to exclude acute testicular torsion and a biopsy was taken during surgery for histological examination. Histology revealed severe LO with reduced spermatogenesis. A trial of oral steroids was initially effective but the effect was temporary...
August 2015: Canadian Journal of Urology
https://www.readbyqxmd.com/read/26139500/comparison-of-percutaneous-extraperitoneal-closure-lpec-and-open-repair-for-pediatric-inguinal-hernia-experience-of-a-single-institution-with-over-1000-cases
#15
COMPARATIVE STUDY
Hiromu Miyake, Koji Fukumoto, Masaya Yamoto, Hiroshi Nouso, Masakatsu Kaneshiro, Hideaki Nakajima, Mariko Koyama, Naoto Urushihara
BACKGROUND: Recently, laparoscopic percutaneous extraperitoneal closure (LPEC) for pediatric inguinal hernia has become more popular. The aim of this study was to compare LPEC with open repair (OR) performed in one institution. METHODS: In total, 1050 patients underwent OR from July 2003 to June 2008, and 1017 patients underwent LPEC from July 2008 to June 2013. The mean follow-up period was 100 months in OR and 40 months in LPEC (p < 0.01). Given the difference in the follow-up periods, the log-rank test was used for the analysis of the long-term results...
April 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26124191/unexpected-toxicology-findings-in-rats-dosed-with-an-antihuman-il-13-monoclonal-antibody
#16
Pauline L Martin, Ivo P Nnane, Patrick Branigan, Calvert Louden
Interleukin 13 (IL-13) is a type 2 helper T cytokine involved in allergic inflammation and immune responses to parasites. CNTO5825 is an antihuman IL-13 monoclonal antibody that inhibits the pharmacological activity of human, cynomolgus monkey, and rat IL-13. Repeated dose toxicology studies of 1- to 6-month duration were conducted in both rats and monkeys at doses of 20 to 100 mg/kg/wk. A decrease in the T cell-dependent antibody response to Keyhole Limpet Hemocyanin immunization was observed in monkeys but not in rats...
September 2015: International Journal of Toxicology
https://www.readbyqxmd.com/read/25957187/natural-history-of-testicular-size-in-boys-with-varicoceles
#17
S Khasnavis, B A Kogan
INTRODUCTION: Testicular size is commonly used as a proxy for future fertility in adolescent boys diagnosed with varicoceles. Surgery is often performed based on a 15-20% reduction in volume of the ipsilateral testicle when compared to the unaffected side. Recent European Association of Urology guidelines, however, have highlighted the risk of overtreatment. Data on the natural progression of testicular size discrepancy are limited in this population. To evaluate the role of a non-surgical approach, the present study reports on testicular size progression in 35 boys with left-sided varicoceles managed with observation alone...
June 2015: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/25946566/laparoscopic-interrupted-muscular-arch-repair-in-recurrent-unilateral-inguinal-hernia-among-children
#18
Sherif M Shehata, Akram M ElBatarny, Mohamed A Attia, Ashraf A El Attar, AbdelGhani M Shalaby
PURPOSE: We present a procedure of suturing the transversus abdominis muscular arch to the ileopubic tract laparoscopically in order to repair recurrent unilateral pediatric inguinal hernia (PIH). PATIENTS AND METHODS: Twenty-five children with recurrent unilateral PIH were treated during a 5-year period in a tertiary academic center. All cases were subjected to laparoscopic hernia repair and discharged the next morning. Sutures were placed from the muscular arch to the ileopubic tract, avoiding the spermatic vessels and duct, in an interrupted manner using 2/0-3/0 polypropylene (Prolene®; Ethicon, Somerville, NJ) or polyglactin 910 (Vicryl®; Ethicon) sutures...
August 2015: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/25672281/a-modified-technique-of-laparoscopic-mobilisation-and-transfer-of-intra-abdominal-testis-via-inguinal-canal
#19
Pankaj Kumar Mishra, Clara Chong, Thomas Tsang
Several techniques have been described for mobilising intra-abdominal testis (IAT) into the scrotum. Many are associated with significant morbidity. We hereby introduce our modification of the technique that is safe and reproducible. Surgical technique using a nylon tape to railroad instruments into the peritoneal cavity to minimise false passage and trauma is described in detail. Once the testis is delivered out of the scrotal wound, further division of restrictive bands to mobilise the testis is carried out laparoscopically...
April 2015: Pediatric Surgery International
https://www.readbyqxmd.com/read/25644487/a-purse-string-suture-at-the-level-of-internal-inguinal-ring-taking-only-the-peritoneum-leaving-the-distal-sac-is-it-enough-for-inguinal-hernia-in-pediatric-patients
#20
D Y Lee, Y H Baik, B S Kwak, M G Oh, W Y Choi
PURPOSE: Although laparoscopic surgery in children has expanded in recent years. Laparoscopic hernia repair in children is still debatable. We aimed to summarize and describe our results of laparoscopic inguinal hernia repair and techniques among children. METHODS: Between March 2011 and April 2013, 98 children (67 male, 31 female) underwent laparoscopic inguinal hernia repair at the department of surgery. The clinical outcomes were collected retrospectively. RESULTS: The mean follow-up period was 22...
August 2015: Hernia: the Journal of Hernias and Abdominal Wall Surgery
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