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https://www.readbyqxmd.com/read/28651422/-meta-analysis-on-the-diagnostic-value-of-laser-doppler-imaging-for-burn-depth
#1
Y Huang, L Qiu, A L Mei, J X Li
Objective: To evaluate the value of laser Doppler imaging (LDI) in diagnosing deep or superficial partial-thickness burn wound with meta-analysis. Methods: Databases including PubMed, Cochrane Library were searched using key words " burn, burns, burn depth, laser Doppler imaging, laser Doppler perfusion imaging, LDI, LDPI" , and Chinese Journals Full-text Database, Wanfang Database, VIP Database were searched using Chinese key words ",,,," to obtain the published trials of LDI in diagnosing deep or superficial partial-thickness burn wound from the establishment of each database to October 2015...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28651420/-effects-of-hypoxia-inducible-factor-1%C3%AE-on-p311-and-its-influence-on-the-migration-of-murine-epidermal-stem-cells
#2
Z D Xu, H S Li, S Wang, W F He, J Wu, G X Luo
Objective: To explore the effects of hypoxia inducible factor-1α (HIF-1α) on P311 and its influence on the migration of murine epidermal stem cells (ESCs) under hypoxia in vitro. Methods: Two kinds of murine ESCs were isolated and obtained from 15 neonatal wild-type C57BL/6J mice and 5 congeneric source P311 gene knock-out mice, respectively. The first passage of cells were used in the following experiments after morphologic observation and detection of expression of cell surface markers CD71 and CD49f with flow cytometer...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28651356/heterologous-expression-in-pichia-pastoris-and-biochemical-characterization-of-the-unmodified-sulfatase-from-fusarium-proliferatum-le1
#3
Svetlana A Korban, Kirill S Bobrov, Maria A Maynskova, Stanislav N Naryzhny, Olga L Vlasova, Elena V Eneyskaya, Anna A Kulmisnkaya
Sulfatases are a family of enzymes (sulfuric ester hydrolases, EC 3.1.6.-) that catalyze the hydrolysis of a wide array of sulfate esters. To date, despite the discovery of many sulfatase genes and the accumulation of data on numerous sulfated molecules, the number of characterized enzymes that are key players in sulfur metabolism remains extremely limited. While mammalian sulfatases are well studied due to their involvement in a wide range of normal and pathological biological processes, lower eukaryotic sulfatases, especially fungal sulfatases, have not been thoroughly investigated at the biochemical and structural level...
June 23, 2017: Protein Engineering, Design & Selection: PEDS
https://www.readbyqxmd.com/read/28651352/circular-rna-profiling-reveals-that-circular-rnas-from-anxa2-can-be-used-as-new-biomarkers-for-multiple-sclerosis
#4
Iparraguirre Leire, Muñoz-Culla Maider, Prada Iñigo, Castillo-Triviño Tamara, Olascoaga Javier, Otaegui David
Multiple Sclerosis is an autoimmune disease, with higher prevalence in women, in whom the immune system is dysregulated. This dysregulation has been shown to correlate with changes in transcriptome expression as well as in gene-expression regulators, such as non-coding RNAs (e.g. microRNAs). Indeed, some of these have been suggested as biomarkers for multiple sclerosis even though few biomarkers have reached the clinical practice.Recently, a novel family of non-coding RNAs, circular RNAs, has emerged as a new player in the complex network of gene-expression regulation...
June 23, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28651314/stabilization-of-heavy-metals-in-soil-using-two-organo-bentonites
#5
Kai Yu, Jian Xu, Xiaohong Jiang, Cun Liu, Wesley McCall, Jinlong Lu
Stabilization of Cu, Zn, Cd, Hg, Cr and As in soil using tetramethylammonium (TMA) and dodecyltrimethylammonium (DTMA) modified bentonites (T-Bents and D-Bents) as amendments was investigated. Toxicity characteristic leaching procedure (TCLP) was used to quantify the metal mobility after soil treatment. The structural parameters of modified bentonites, including the BET surface area, basal spacing and zeta potential were obtained as a function of the TMA and DTMA loading at 40, 80, 120, 160 and 200% of the bentonite's cation exchange capacity, respectively...
June 20, 2017: Chemosphere
https://www.readbyqxmd.com/read/28651221/risk-element-immobilization-stabilization-potential-of-fungal-transformed-dry-olive-residue-and-arbuscular-mycorrhizal-fungi-application-in-contaminated-soils
#6
Mercedes García-Sánchez, Tereza Stejskalová, Inmaculada García-Romera, Jiřina Száková, Pavel Tlustoš
The use of biotransformed dry olive residue (DOR) as organic soil amendment has recently been proposed due to its high contents of stabilized organic matter and nutrients. The potential of biotransformed DOR to immobilize risk elements in contaminated soils might qualify DOR as a potential risk element stabilization agent for in situ soil reclamation practices. In this experiment, the mobility of risk elements in response to Penicillium chrysogenum-10-transformed DOR, Funalia floccosa-transformed DOR, Bjerkandera adusta-transformed DOR, and Chondrostereum purpureum-transformed DOR as well as arbuscular mycorrhizal fungi (AMF), Funneliformis mosseae, inoculation was investigated...
June 23, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28651220/clozapine-versus-other-antipsychotics-during-the-first-18-weeks-of-treatment-a-retrospective-study-on-risk-factor-increase-of-blood-dyscrasias
#7
Michele Fabrazzo, Vincenzo Prisco, Gaia Sampogna, Francesco Perris, Francesco Catapano, Alessio Maria Monteleone, Mario Maj
Blood dyscrasias excluding agranulocytosis received limited attention in antipsychotic-treated patients during the first 18 weeks of therapy, although severe clinical conditions have been reported in a few cases. We extracted data records of 285 Caucasian patients after 18 weeks of antipsychotic treatments to investigate risk factors of blood dyscrasias. We observed a higher risk to develop both transient and persistent anemia, neutrophilia and eosinophilia in clozapine-treated patients, whereas in those treated with other atypical antipsychotics when compared to a reference group under typical antipsychotics, emerged an increased risk for transient neutrophilia and eosinophilia...
June 20, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28651217/modeling-in-sewer-transformations-at-catchment-scale-implications-on-drug-consumption-estimates-in-wastewater-based-epidemiology
#8
Ann-Kathrin McCall, Rocco Palmitessa, Frank Blumensaat, Eberhard Morgenroth, Christoph Ort
To which extent illicit drugs are transformed during in-sewer transport, depends on a number of factors: i) substance-specific transformation rates, ii) environmental conditions, iii) point of discharge (location of drug user) and iv) sewer network properties, primarily hydraulic residence time (HRT) and the ratio of biofilm contact area to wastewater volume (A/Veq). Assessing associated uncertainties typically requires numerous simulations. Therefore, we propose a new two-step modeling framework: 1) Quantify hydrodynamic conditions...
May 20, 2017: Water Research
https://www.readbyqxmd.com/read/28651216/ultra-sensitive-suspended-atomically-thin-layered-black-phosphorus-mercury-sensors
#9
Peng Li, Dongzhi Zhang, Chuanxing Jiang, Xiaoqi Zong, Yuhua Cao
The extraordinary properties of black phosphorus (BP) make it a promising candidate for next-generation transistor chemical sensors. However, BP films reported so far are supported on substrate, and substrate scattering drastically deteriorates its electrical properties. Consequentially, the potential sensing capability of intrinsic BP is highly underestimated and its sensing mechanism is masked. Additionally, the optimum sensing regime of BP remains unexplored. This article is the first demonstration of suspended BP sensor operated in subthreshold regime...
June 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28651203/carbon-coated-zno-mat-passivation-by-atomic-layer-deposited-hfo2-as-an-anode-material-for-lithium-ion-batteries
#10
Mi-Hee Jung
ZnO has had little consideration as an anode material in lithium-ion batteries compared with other transition-metal oxides due to its inherent poor electrical conductivity and large volume expansion upon cycling and pulverization of ZnO-based electrodes. A logical design and facile synthesis of ZnO with well-controlled particle sizes and a specific morphology is essential to improving the performance of ZnO in lithium-ion batteries. In this paper, a simple approach is reported that uses a cation surfactant and a chelating agent to synthesize three-dimensional hierarchical nanostructured carbon-coated ZnO mats, in which the ZnO mats are composed of stacked individual ZnO nanowires and form well-defined nanoporous structures with high surface areas...
June 20, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28651201/ex-situ-decoration-of-ordered-mesoporous-carbon-with-palladium-nanoparticles-via-polyoxometalates-and-for-sensitive-detection-of-acetaminophen-in-pharmaceutical-products
#11
Xiangyi Kong, Yeyu Wang, Qianqian Zhang, Tongrui Zhang, Qianqian Teng, Lei Wang, Huan Wang, Yufan Zhang
In this study, a facile and green method is described for decoration of ordered mesoporous carbon (OMC) with palladium nanoparticles (Pd NPs) through a polyoxometalates (POMs). Serving as both reducing and stabilizing agent, the Keggin-type POMs are used for synthesis of stable colloidal Pd NPs and then link them to the OMC at mild temperature. Current research focuses on the use of Pd-POMs-OMC as an effective sensing template for the detection of acetaminophen (AP) has been studied. Linear calibration curves in the range of 0...
June 20, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28651193/p-p-methoxyl-diphenyl-diselenideincorporation-into-polymeric-nanocapsules-improves-its-antinociceptive-action-physicochemical-and-behavioral-studies
#12
Marcel Henrique Marcondes Sari, Luana Mota Ferreira, Vanessa AngonesiZborowski, Paulo Cesar Oliveira Araujo, Jessica Mendes Nadal, Paulo Vitor Farago, Letícia Cruz, Cristina Wayne Nogueira
The p,p'-methoxyl-diphenyl diselenide [(OMePhSe)2] is an, organoselenium compound that elicits antinociceptive action in different, animal models of pain. However, the compound has physicochemical, Limitations that delay its clinical studies. Herein, (OMePhSe)2, nanocapsules were developed and their physicochemical properties were, analyzed using different techniques (Scanning electron microscopy with, field emissionguns, wide-angle X-ray diffractometry, fourier-transform, infrared spectroscopy, thermogravimetric analysis and differential, scanning calorimetry)...
June 20, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28651154/new-comprehensive-studies-of-a-gold-iii-dithiocarbamate-complex-with-proven-anticancer-properties-aqueous-dissolution-with-cyclodextrins-pharmacokinetics-and-upstream-inhibition-of-the-ubiquitin-proteasome-pathway
#13
Marianna F Tomasello, Chiara Nardon, Valeria Lanza, Giuseppe Di Natale, Nicolò Pettenuzzo, Stefano Salmaso, Danilo Milardi, Paolo Caliceti, Giuseppe Pappalardo, Dolores Fregona
The gold(III)-dithiocarbamate complex AuL12 (dibromo [ethyl-N-(dithiocarboxy-kS,kS')-N-methylglycinate] gold(III)), is endowed with promising in vitro/in vivo antitumor activity and toxicological profile. Here, we report our recent strategies to improve its water solubility and stability under physiological conditions along with our efforts for unravelling its tangled mechanism of action. We used three types of α-cyclodextrins (CDs), namely β-CD, Me-β-CD and HP-β-CD to prepare aqueous solutions of AuL12...
June 19, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28650975/defective-glucocorticoid-receptor-signaling-and-keratinocyte-autonomous-defects-contribute-to-skin-phenotype-of-mouse-embryos-lacking-the-hsp90-co-chaperone-p23
#14
Marta Madon-Simon, Iwona Grad, Pilar Bayo, Paloma Pérez, Didier Picard
p23 is a small acidic protein with intrinsic molecular chaperone activity. It is best known as a co-chaperone of the major cytosolic molecular chaperone Hsp90. p23 binds the N-terminus of Hsp90 and stabilizes the ATP-bound and N-terminally closed Hsp90 dimer. It is in this configuration that many Hsp90 clients are most stably bound. Considering the important role of p23 in the Hsp90 cycle, it came as a surprise that it is not absolutely essential for viability in the budding yeast or for mouse development. Mice without p23 develop quite normally until birth and then all die perinatally because of immature lungs...
2017: PloS One
https://www.readbyqxmd.com/read/28650838/adaptive-neural-network-finite-time-output-feedback-control-of-quantized-nonlinear-systems
#15
Fang Wang, Bing Chen, Chong Lin, Jing Zhang, Xinzhu Meng
This paper addresses the finite-time tracking issue for nonlinear quantized systems with unmeasurable states. Compared with the existing researches, the finite-time quantized feedback control is considered for the first time. By proposing a new finite-time stability criterion and designing a state observer, a novel adaptive neural output-feedback control strategy is raised by backstepping technique. Under the presented control scheme, the finite-time quantized feedback control problem is coped with without limiting assumption for nonlinear functions...
June 26, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28650833/exponential-stabilization-of-memristive-neural-networks-via-saturating-sampled-data-control
#16
Sanbo Ding, Zhanshan Wang, Nannan Rong, Huaguang Zhang
This paper is concerned with the exponential stabilization of memristive neural networks (MNNs) by taking into account the sampled-data control and actuator saturation. On the one hand, the MNNs are converted into a tractable model by defining a class of logical switched functions. Based on this model, the connection weights of MNNs are dealt with by a robust analysis method. On the other hand, a saturating sampled-data controller containing an exponentially decaying term is designed. With the help of generalized sector condition and the Lyapunov stability theory, a novel sufficient condition ensuring the local exponential stability of the closed-loop systems is formulated in terms of linear matrix inequalities...
June 22, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28650826/delayed-feedback-control-for-stabilization-of-boolean-control-networks-with-state-delay
#17
Rongjian Liu, Jianquan Lu, Yang Liu, Jinde Cao, Zheng-Guang Wu
In this brief, we study the delayed feedback stabilization problem for Boolean control networks (BCNs) with state delay. Using the semi-tensor product of matrices, some necessary and sufficient conditions are obtained. For the stabilization of BCNs, detailed procedure to construct the feedback controllers is also presented. We further derive the number of different feedback controllers, which can successfully stabilize the BCN in a finite time. Finally, an illustrative example is presented to show the effectiveness of our method...
June 22, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28650796/comparison-of-bovine-bone-autogenic-bone-mixture-versus-platelet-rich-fibrin-for-maxillary-sinus-grafting-histologic-and-histomorphologic-study
#18
Hakan Ocak, Nukhet Kutuk, Umut Demetoglu, Esra Balcıoglu, Saim Ozdamar, Alper Alkan
Numerous grafting materials have been used to augment the maxillary sinus floor for long-term stability and success for implant-supported prosthesis. To enhance bone formation, adjunctive blood-born growth factor sources have gained popularity during the recent years. The present study compared the use of platelet-rich fibrin (PRF) and bovine-autogenous bone mixture for maxillary sinus floor elevation. A split-face model was used to apply 2 different filling materials for maxillary sinus floor elevation in 22 healthy adult sheep...
June 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28650686/the-influence-of-limb-alignment-and-transfemoral-amputation-technique-on-muscle-capacity-during-gait
#19
Ellyn C Ranz, Jason M Wilken, Donald A Gajewski, Richard R Neptune
Many factors influence successful outcomes following transfemoral amputation. One factor is surgical technique. In this study, the influence of limb alignment and surgical technique on a muscle's capacity to generate force was examined using musculoskeletal modeling. Non-amputee and transfemoral amputee models were analyzed while hip adduction, femur length, and reattached muscle wrap position, tension and stabilization technique were systematically varied. With muscle tension preserved, wrap position and femur length had little influence on muscle capacity...
June 26, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28650679/establishing-maximal-medical-improvement-after-arthroscopic-rotator-cuff-repair
#20
William A Zuke, Timothy S Leroux, Bonnie P Gregory, Austin Black, Brian Forsythe, Anthony A Romeo, Nikhil N Verma
BACKGROUND: As health care transitions from a pay-for-service to a pay-for-performance infrastructure, the value of orthopaedic care must be defined accurately. Significant efforts have been made in defining quality and cost in arthroplasty; however, there remains a lag in ambulatory orthopaedic care. PURPOSE: Two-year follow-up has been a general requirement for reporting outcomes after rotator cuff repair. However, this time requirement has not been established scientifically and is of increasing importance in the era of value-based health care...
June 1, 2017: American Journal of Sports Medicine
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