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https://www.readbyqxmd.com/read/28110486/spectra-optia-%C3%A2-for-automated-red-blood-cell-exchange-in-patients-with-sickle-cell-disease-a-nice-medical-technology-guidance
#1
REVIEW
Iain Willits, Helen Cole, Roseanne Jones, Kimberley Carter, Mick Arber, Michelle Jenks, Joyce Craig, Andrew Sims
The Spectra Optia(®) automated apheresis system, indicated for red blood cell exchange in people with sickle cell disease, underwent evaluation by the National Institute for Health and Care Excellence, which uses its Medical Technologies Advisory Committee to make recommendations. The company (Terumo Medical Corporation) produced a submission making a case for adoption of its technology, which was critiqued by the Newcastle and York external assessment centre. Thirty retrospective observational studies were identified in their clinical submission...
January 21, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28108913/religion-and-public-health-moral-tradition-as-both-problem-and-solution
#2
Michael Rozier
Despite strong religious influence in the development of medicine and medical ethics, religion has been relatively absent in the rise of preventive medicine and population health. Episodic, clinical medicine has a powerful hold on the religious imagination in health care. Nevertheless, Hebrew Scripture, elements of rabbinical teaching, and modern concepts of social justice all can be used to inspire action in health care that goes beyond clinical medicine. The Christian tradition can call upon the corporal works of mercy, virtue ethics, and Catholic social teaching, as well as the modern history Catholic sisters in the U...
January 20, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28099060/understanding-medicaid-managed-care-investments-in-members-social-determinants-of-health
#3
Laura Gottlieb, Sara Ackerman, Holly Wing, Rishi Manchanda
Despite widespread interest in addressing social determinants of health (SDH) as a means to improve health and to reduce health care spending, little information is available about how to develop, sustain, and scale nonmedical interventions in diverse payer environments, including Medicaid Managed Care. This study aimed to explore how Medicaid Managed Care Organization (MMCO) leaders interpret their roles and responsibilities around SDH, how they garner resources to develop and sustain interventions to address SDH, and how they perceive the influences of external organizations on related activities...
January 18, 2017: Population Health Management
https://www.readbyqxmd.com/read/28071266/biogen-s-portfolio-and-research-efforts-in-multiple-sclerosis-an-interview-with-dr-ralph-kern
#4
Ralph Kern
Ralph Kern speaks to Laura Dormer, Commissioning Editor: Dr Ralph Kern is Senior Vice President and Head of Worldwide Medical at Biogen in Cambridge, MA, USA. In this role, he oversees Biogen's global therapeutic, regional and country medical teams, global medical operations, as well as medical research and scientific communications functions. Prior to joining Biogen, he was head of the Neuroscience Medical Unit at Novartis Pharmaceuticals Corporation and held various medical and commercial leadership roles at Genzyme Corporation...
January 10, 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28068789/pragmatic-trial-of-video-education-in-nursing-homes-the-design-and-rationale-for-a-pragmatic-cluster-randomized-trial-in-the-nursing-home-setting
#5
Vincent Mor, Angelo E Volandes, Roee Gutman, Constantine Gatsonis, Susan L Mitchell
Background/Aims Nursing homes are complex healthcare systems serving an increasingly sick population. Nursing homes must engage patients in advance care planning, but do so inconsistently. Video decision support tools improved advance care planning in small randomized controlled trials. Pragmatic trials are increasingly employed in health services research, although not commonly in the nursing home setting to which they are well-suited. This report presents the design and rationale for a pragmatic cluster randomized controlled trial that evaluated the "real world" application of an Advance Care Planning Video Program in two large US nursing home healthcare systems...
January 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28050981/intricate-evaluation-of-association-between-dental-caries-and-obesity-among-the-children-in-al-kharj-city-saudi-arabia
#6
Mohammed As Abu El Qomsan, Mohammed N Alasqah, Fahad A Alqahtani, Mohammed Aa Alobaydaa, Muteb M Alharbi, Zaheer Kola
INTRODUCTION: Dental caries and obesity are two of the most prevalent health conditions affecting children. Relative decrease in corporeal movements, escalating inactive lifestyles, and changes in dietary factors are strongly linked with the increasing incidence of overweight and obesity. Furthermore, obesity increases the risk of chronic disease and dental caries that significantly affects the quality of life of young children. The present study intends to explore the relationship between dental caries and obesity in children in Al-Kharj city, Kingdom of Saudi Arabia...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28026703/corporate-sponsorship-of-global-health-research-questions-to-promote-critical-thinking-about-potential-funding-relationships
#7
Ben W Brisbois, Donald C Cole, Colleen M Davison, Erica Di Ruggiero, Lori Hanson, Craig R Janes, Charles P Larson, Stephanie Nixon, Katrina Plamondon, Bjorn Stime
Funding options for global health research prominently include grants from corporations, as well as from foundations linked to specific corporations. While such funds can enable urgently-needed research and interventions, they can carry the risk of skewing health research priorities and exacerbating health inequities. With the objective of promoting critical reflection on potential corporate funding options for global health research, we propose a set of three questions developed through an open conference workshop and reflection on experiences of global health researchers and their institutions: 1) Does this funding allow me/us to retain control over research design, methodology and dissemination processes? 2) Does accessing this funding source involve altering my/our research agenda (i...
December 27, 2016: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/27993961/support-and-performance-improvement-for-primary-health-care-workers-in-low-and-middle-income-countries-a-scoping-review-of-intervention-design-and-methods
#8
REVIEW
Ashwin Vasan, David C Mabey, Simran Chaudhri, Helen-Ann Brown Epstein, Stephen D Lawn
Primary health care workers (HCWs) in low- and middle-income settings (LMIC) often work in challenging conditions in remote, rural areas, in isolation from the rest of the health system and particularly specialist care. Much attention has been given to implementation of interventions to support quality and performance improvement for workers in such settings. However, little is known about the design of such initiatives and which approaches predominate, let alone those that are most effective. We aimed for a broad understanding of what distinguishes different approaches to primary HCW support and performance improvement and to clarify the existing evidence as well as gaps in evidence in order to inform decision-making and design of programs intended to support and improve the performance of health workers in these settings...
December 19, 2016: Health Policy and Planning
https://www.readbyqxmd.com/read/27884153/performance-evaluation-of-the-touchscreen-based-muse%C3%A2-auto-cd4-cd4-single-platform-system-for-cd4-t-cell-numeration-in-absolute-number-and-in-percentage-using-blood-samples-from-children-and-adult-patients-living-in-the-central-african-republic
#9
Christian Diamant Mossoro-Kpinde, André Kouabosso, Ralph-Sydney Mboumba Bouassa, Jean De Dieu Longo, Edouard Kokanzo, Rosine Féissona, Gérard Grésenguet, Laurent Bélec
BACKGROUND: The new microcapillary and fluorescence-based EC IVD-qualified Muse™ Auto CD4/CD4% single-platform assay (EMD Millipore Corporation, Merck Life Sciences, KGaA, Darmstadt, Germany) for CD4 T cell numeration in absolute number and in percentage was evaluated using Central African patients' samples compared against the reference EC IVD-qualified BD FACSCount (Becton-Dickinson, USA) flow cytometer. METHODS: EDTA-blood samples from 124 adults, 10 adolescents, 13 children and 3 infants were tested in parallel at 2 reference laboratories in Bangui...
November 25, 2016: Journal of Translational Medicine
https://www.readbyqxmd.com/read/27854179/health-applications-for-corporate-health-management
#10
Guido Steigner, Charles R Doarn, Michael Schütte, David Matusiewicz, Christian Thielscher
INTRODUCTION: Many corporate organizations around the world are looking at new ways to improve the health and well-being of their employees. Many have begun to use m-health approaches and unique applications (apps) to provide assistance. In Germany, both m-health and occupational health management (OHM) are growing quickly. Therefore, we hypothesized that the combination-apps usage in OHM-is growing as well. We studied the usage of health apps in large corporations for health management of employed individuals...
November 17, 2016: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/27826203/economic-impact-of-longer-battery-life-of-cardiac-resynchronization-therapy-defibrillators-in-sweden
#11
Fredrik Gadler, Yao Ding, Nathalie Verin, Martin Bergius, Jeffrey D Miller, Gregory M Lenhart, Mason W Russell
OBJECTIVE: The objective of this study was to quantify the impact that longer battery life of cardiac resynchronization therapy defibrillator (CRT-D) devices has on reducing the number of device replacements and associated costs of these replacements from a Swedish health care system perspective. METHODS: An economic model based on real-world published data was developed to estimate cost savings and avoided device replacements for CRT-Ds with longer battery life compared with devices with industry-standard battery life expectancy...
2016: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/27814729/assessment-of-the-scope-and-practice-of-evaluation-among-medical-donation-programs
#12
Alisa M Jenny, Meng Li, Elizabeth Ashbourne, Myron Aldrink, Christine Funk, Andy Stergachis
BACKGROUND: Medical donation programs for drugs, other medical products, training and other supportive services can improve access to essential medicines in low- and middle-income countries (LMICs) and provide emergency and disaster relief. The scope and extent to which medical donation programs evaluate their impact on recipients and health systems is not well documented. METHODS: We conducted a survey of the member organizations of the Partnership for Quality Medical Donations (PQMD), a global alliance of non-profit and corporate organizations, to identify evaluations conducted in conjunction with donation programs...
November 4, 2016: Globalization and Health
https://www.readbyqxmd.com/read/27761683/the-association-of-minority-self-rated-health-with-black-versus-white-gentrification
#13
Joseph Gibbons, Michael S Barton
There exists controversy as to the impact gentrification of cities has on the well-being of minorities. Some accuse gentrification of causing health disparities for disadvantaged minority populations residing in neighborhoods that are changing as a result of these socioeconomic shifts. Past scholarship has suggested that fears of displacement and social isolation associated with gentrification lead to poorer minority health. However, there is a lack of research that directly links gentrification to minority health outcomes...
December 2016: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/27747516/psoriatic-arthritis-and-burden-of-disease-patient-perspectives-from-the-population-based-multinational-assessment-of-psoriasis-and-psoriatic-arthritis-mapp-survey
#14
Arthur Kavanaugh, Philip Helliwell, Christopher T Ritchlin
INTRODUCTION: Psoriatic arthritis (PsA) is underdiagnosed and has a substantial impact on quality of life, disability, and work productivity. The population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) survey examined the impact of PsA on patients' activities of daily living and unmet treatment needs. METHODS: This large-scale, random digit dialing, telephone survey of patients self-reporting a diagnosis of psoriasis and/or PsA was conducted in North America and Europe...
June 2016: Rheumatology and Therapy
https://www.readbyqxmd.com/read/27746745/pressure-induced-changes-in-adaptive-immune-function-in-belugas-delphinapterus-leucas-implications-for-dive-physiology-and-health
#15
Laura A Thompson, Tracy A Romano
Increased pressure, associated with diving, can alter cell function through several mechanisms and has been shown to impact immune functions performed by peripheral blood mononuclear cells (PBMC) in humans. While marine mammals possess specific adaptations which protect them from dive related injury, it is unknown how their immune system is adapted to the challenges associated with diving. The purpose of this study was to measure PBMC activation (IL2R expression) and Concanavalin A induced lymphocyte proliferation (BrdU incorporation) in belugas following in vitro pressure exposures during baseline, Out of Water Examination (OWE) and capture/release conditions...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27745783/sponsorship-of-national-health-organizations-by-two-major-soda-companies
#16
Daniel G Aaron, Michael B Siegel
INTRODUCTION: Obesity is a pervasive public health problem in the U.S. Reducing soda consumption is important for stemming the obesity epidemic. However, several articles and one book suggest that soda companies are using their resources to impede public health interventions that might reduce soda consumption. Although corporate sponsorship by tobacco and alcohol companies has been studied extensively, there has been no systematic attempt to catalog sponsorship activities of soda companies...
January 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/27707151/addressing-current-and-future-challenges-for-the-nhs-the-role-of-good-leadership
#17
Lotte Elton
Purpose This paper aims to describe and analyse some of the ways in which good leadership can enable those working within the National Health Service (NHS) to weather the changes and difficulties likely to arise in the coming years, and takes the format of an essay written by the prize-winner of the Faculty of Medical Leadership and Management's Student Prize. The Faculty of Medical Leadership and Management ran its inaugural Student Prize in 2015-2016, which aimed at medical students with an interest in medical leadership...
October 3, 2016: Leadership in Health Services
https://www.readbyqxmd.com/read/27661467/the-marketing-potential-of-corporate-social-responsibility-activities-the-case-of-the-alcohol-industry-in-latin-america-and-the-caribbean
#18
Daniela Pantani, Raquel Peltzer, Mariana Cremonte, Katherine Robaina, Thomas Babor, Ilana Pinsky
BACKGROUND AND AIMS: To 1) identify, monitor and analyze the Corporate Social Responsibility (CSR) practices of the alcohol industry in Latin American and the Caribbean (LAC) and 2) examine whether the alcohol industry is using these actions to market their products and brands. METHODS: Nine health experts from Argentina, Brazil and Uruguay conducted a content analysis of 218 CSR activities using a standardized protocol. A content rating procedure was used to evaluate the marketing potential of CSR activities as well as their likely population reach and effectiveness...
September 23, 2016: Addiction
https://www.readbyqxmd.com/read/27647945/parental-aggression-as-a-predictor-of-boys-hostile-attribution-across-the-transition-to-middle-school
#19
Anna Yaros, John E Lochman, Karen C Wells
Aggression among youth is public health problem that is often studied in the context of how youth interpret social information. Social cognitive factors, especially hostile attribution biases, have been identified as risk factors for the development of youth aggression, particularly across the transition to middle school. Parental behaviors, including parental aggression to children in the form of corporal punishment and other aggressive behavior, have also been linked to aggressive behavior in children at these ages...
September 2016: International Journal of Behavioral Development
https://www.readbyqxmd.com/read/27636883/diageo-s-stop-out-of-control-drinking-campaign-in-ireland-an-analysis
#20
Mark Petticrew, Niamh Fitzgerald, Mary Alison Durand, Cécile Knai, Martin Davoren, Ivan Perry
BACKGROUND: It has been argued that the alcohol industry uses corporate social responsibility activities to influence policy and undermine public health, and that every opportunity should be taken to scrutinise such activities. This study analyses a controversial Diageo-funded 'responsible drinking' campaign ("Stop out of Control Drinking", or SOOCD) in Ireland. The study aims to identify how the campaign and its advisory board members frame and define (i) alcohol-related harms, and their causes, and (ii) possible solutions...
2016: PloS One
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